DRNA


Line plots across dimensions of each concept
Line plots across concepts
Tables

Table of contents



us-gaap:CommonStockValue

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:ComprehensiveIncomeNetOfTax

us-gaap:GeneralAndAdministrativeExpense

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

us-gaap:IncomeTaxExpenseBenefit

us-gaap:InterestExpense

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:NonoperatingIncomeExpense

us-gaap:OperatingExpenses

us-gaap:OperatingIncomeLoss

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:ResearchAndDevelopmentExpense

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:TypeOfArrangement

us-gaap:Revenues

us-gaap:Assets

us-gaap:Liabilities

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents

us-gaap:AssetsCurrent

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:ReceivablesNetCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:AssetsNoncurrent

us-gaap:PropertyPlantAndEquipmentGross
us-gaap:PropertyPlantAndEquipmentByType

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:OperatingLeaseRightOfUseAsset
us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

us-gaap:OtherAssetsNoncurrent

us-gaap:AccountsPayableCurrent

us-gaap:ContractWithCustomerLiabilityCurrent
us-gaap:TypeOfArrangement

us-gaap:LiabilitiesCurrent

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OtherAccruedLiabilitiesCurrent

us-gaap:LiabilitiesNoncurrent

us-gaap:OtherLiabilitiesNoncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:OperatingLeaseLiability
us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents

us-gaap:CommonStockValue

us-gaap:AdditionalPaidInCapital

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
us-gaap:StatementEquityComponents

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:DepreciationDepletionAndAmortization

us-gaap:IncreaseDecreaseInAccountsPayable

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:ShareBasedCompensation
us-gaap:IncomeStatementLocation

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:UnrecognizedTaxBenefits

us-gaap:DeferredTaxAssetsValuationAllowance
us-gaap:TypeOfArrangement
drna:AggregateSalesMilestonesReceivableExpense

drna:ChangeInFairValueOfDerivativeLiability
us-gaap:TypeOfArrangement
drna:CollaborativeArrangementConsideration
us-gaap:SubsequentEventType, us-gaap:TypeOfArrangement
drna:CollaborativeArrangementContingentSalesBasedMilestonePaymentReceivable
us-gaap:TypeOfArrangement
drna:CollaborativeArrangementDevelopmentCandidateNominationMilestoneAmountEarned
us-gaap:TypeOfArrangement
drna:CollaborativeArrangementOptionExerciseFee
us-gaap:SubsequentEventType, us-gaap:TypeOfArrangement
drna:CollaborativeArrangementProceedsFromSaleOfRoyaltyInterest

drna:CollaborativeArrangementRightsAndObligationsMaximumAggregateMilestonePayments
us-gaap:TypeOfArrangement
drna:CollaborativeArrangementTargetsDeliveredMilestoneAmountEarned

drna:IncreaseDecreaseInDeferredChargesAndOtherOperatingAssets

drna:IncreaseDecreaseInLeaseLiabilities
us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty
drna:LesseeOperatingLeaseMonthlyBaseRentIncrease

drna:OperatingLeasesIncreaseInRentExpensePerMonth
us-gaap:AwardType
drna:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodFairValue
us-gaap:Range, us-gaap:AwardType
drna:SharePriceOne

us-gaap:AccretionAmortizationOfDiscountsAndPremiumsInvestments

us-gaap:AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation
us-gaap:StatementEquityComponents

us-gaap:CapitalExpendituresIncurredButNotYetPaid

us-gaap:ContractWithCustomerLiabilityRevenueRecognized

us-gaap:ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod
us-gaap:FairValueByLiabilityClass
us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings

us-gaap:IncreaseDecreaseInContractWithCustomerLiability

us-gaap:IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:IncreaseDecreaseInReceivables

us-gaap:InvestmentIncomeInterest

us-gaap:InvestmentIncomeNet

us-gaap:OperatingLeaseExpense

us-gaap:OtherOperatingActivitiesCashFlowStatement

us-gaap:PaymentsForProceedsFromOtherInvestingActivities

us-gaap:PaymentsOfStockIssuanceCosts

us-gaap:PaymentsRelatedToTaxWithholdingForShareBasedCompensation

us-gaap:PaymentsToAcquireHeldToMaturitySecurities

us-gaap:ProceedsFromIssuanceOfCommonStock

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions

us-gaap:ProceedsFromPaymentsForOtherFinancingActivities

us-gaap:ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities

us-gaap:RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
us-gaap:Range, us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
us-gaap:Range, us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
us-gaap:StatementEquityComponents

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised
us-gaap:StatementEquityComponents

drna:AccruedClinicalContractResearchAndManufacturingCostsCurrent
us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty
drna:AdditionalAreaOfRealEstateProperty
us-gaap:FinancialInstrument
drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedGainCurrent
us-gaap:FinancialInstrument
drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossCurrent
us-gaap:FinancialInstrument
drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossNoncurrent

drna:DeferredTaxAssetsLiabilitiesPropertyPlantAndEquipment

drna:DeferredTaxAssetsOperatingLeaseLiability

drna:DeferredTaxLiabilitiesContractWithCustomerLiability
us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty
drna:LesseeOperatingLeaseLeaseNotYetCommencedLiability
us-gaap:Range, us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty
drna:LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount

drna:OperatingAndFinanceLeaseLiabilityCurrent

drna:OperatingAndFinanceLeaseLiabilityNoncurrent

drna:OperatingLossCarryforwardsEstimatedLimitation

drna:OtherPrepaidExpenseAndOtherAssetsCurrent

drna:PrepaidClinicalContractResearchAndManufacturingCostsCurrent

us-gaap:AccruedEmployeeBenefitsCurrent

us-gaap:AccruedLiabilitiesAndOtherLiabilities

us-gaap:AccruedProfessionalFeesCurrent

us-gaap:AreaOfRealEstateProperty
us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

us-gaap:AssetsFairValueDisclosure
us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:CashAndCashEquivalents
us-gaap:CashAndCashEquivalentsFairValueDisclosure
us-gaap:CashAndCashEquivalents, us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:ContractWithCustomerLiability
us-gaap:TypeOfArrangement

us-gaap:ContractWithCustomerLiabilityNoncurrent
us-gaap:TypeOfArrangement
us-gaap:FinancialInstrument
us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLoss

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossCurrent
us-gaap:FinancialInstrument

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossNoncurrent
us-gaap:FinancialInstrument
us-gaap:FinancialInstrument
us-gaap:DebtSecuritiesHeldToMaturityFairValueCurrent
us-gaap:FinancialInstrument
us-gaap:DebtSecuritiesHeldToMaturityFairValueNoncurrent

us-gaap:DeferredIncome

us-gaap:DeferredIncomeCurrent

us-gaap:DeferredIncomeNoncurrent

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredTaxAssetsDerivativeInstruments

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch

us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets

us-gaap:DeferredTaxLiabilitiesLeasingArrangements

us-gaap:DerivativeLiabilities
us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:DerivativeLiabilitiesNoncurrent
us-gaap:AwardType
us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
us-gaap:FairValueByLiabilityClass
us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount

us-gaap:FinanceLeaseRightOfUseAsset

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent

us-gaap:FinancialLiabilitiesFairValueDisclosure
us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:FinancialInstrument
us-gaap:HeldToMaturitySecurities
us-gaap:FinancialInstrument
us-gaap:HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain
us-gaap:FinancialInstrument
us-gaap:HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss

us-gaap:HeldToMaturitySecuritiesCurrent
us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:FinancialInstrument
us-gaap:HeldToMaturitySecuritiesFairValue
us-gaap:FinancialInstrument

us-gaap:HostingArrangementServiceContractImplementationCostCapitalizedAfterAccumulatedAmortization

us-gaap:InterestReceivable

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent
us-gaap:IncomeTaxAuthority
us-gaap:OperatingLossCarryforwards

us-gaap:PrepaidInsurance

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization
us-gaap:PropertyPlantAndEquipmentByType

us-gaap:RestrictedCashAndCashEquivalents

us-gaap:RestrictedCashAndCashEquivalentsAtCarryingValue

us-gaap:RestrictedCashAndCashEquivalentsNoncurrent
us-gaap:LeaseContractualTerm
us-gaap:RestrictedCashEquivalents
us-gaap:CashAndCashEquivalents
us-gaap:RestrictedInvestmentsAtFairValue
us-gaap:CashAndCashEquivalents, us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:RestrictedCashAndCashEquivalentsCashAndCashEquivalents
us-gaap:RestrictedCashAndCashEquivalentsCashAndCashEquivalents
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
us-gaap:Range, us-gaap:AwardType
us-gaap:SharePrice

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
us-gaap:IncomeTaxAuthority
us-gaap:TaxCreditCarryforwardAmount

us-gaap:UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate

Plots across concepts


IncomeStatement
Net Income Loss
Expenses
Other Nonoperating Income Expense
Balance Sheet
Operating Lease Liability
Assets
Property Plant And Equipment Net
Current Assets
Prepaid Expense And Other Assets Current
NonCurrent Assets
Other Assets Noncurrent
PropertyPlantAndEquipmentNet
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Liabilities
Derivative Liabilities
Current Liabilities
Operating Lease Liability Current
Stockholders Equity
Retained Earnings Accumulated Deficit
CashFlow
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInOperatingActivities
Net Income Loss
NetCashProvidedByUsedInInvestingActivities
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInFinancingActivities
Proceeds From Payments For Other Financing Activities
Shares
Weighted Average Number Of Share Outstanding Basic And Diluted
OperatingLeaseLiability
Operating Lease Liability Current
NonoperatingIncomeExpense
Other Nonoperating Income Expense
LesseeOperatingLeaseLiabilityPaymentsDue
Lessee Operating Lease Liability Undiscounted Excess Amount

Tables

  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:CommonStockValue ███▇▇▇▇▇▇▇▇▆▅▅▅▂▂▂▂▂▂▂▂▃▂▂▂▁0.0080.0080.0080.0070.0070.0070.0070.0070.0070.0070.0070.0060.0050.0050.0050.0020.0020.0020.0020.0020.0020.0020.0020.0030.0020.0020.0020.001NANANA
us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding █▁77.02976376.255532NANA74.00112672.919378NANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:WeightedAverageNumberOfSharesOutstandingBasic █▁77.02976376.255532NANA74.00112672.919378NANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted NANANA74.52331974.00112672.919378NA68.36005168.3238568.259354NA54.79964452.55575151.723349NA20.84172820.79419320.791644NA20.752416NA20.5928418.852814NA17.70664517.68456310.822325NA0.0281030.0280950.027952
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount NA16.645002NANANA15.648982NANANA11.193987NANANA7259.879NANANA6147.247NANANANANANANANANANANANANA
 us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities us-gaap:EmployeeStockOptionNA15.356608NANANA14.943084NANANA11.191789NANANA7171.978NANANA6.049346NANANA4.373594NANA3.323387NANANANANANA
 us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities us-gaap:RestrictedStockNA1.288394NANANA0.7037NANANA0.0NANANANANANANA0.01NANANA0.0636370.072772NA0.1044850.1098590.064163NANANANA
us-gaap:EarningsPerShareBasic ▁█-0.53-0.39NANA-0.43-0.31NANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:EarningsPerShareDiluted ▁█-0.53-0.39NANA-0.43-0.31NANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:EarningsPerShareBasicAndDiluted NANA-0.49-0.29-0.43-0.31-0.58-0.45-0.35-0.38-0.29-0.35-0.68-0.3-0.9-0.92-1.15-0.68-0.68-0.68-0.76-0.82-0.86-0.82-0.63-0.64-1.02-199.91-161.55-171.13-172.8
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:ComprehensiveIncomeNetOfTax NANANA-21.849NANANA-30.793NANANA-19.02NANANANANANANANANANANANANANANANANANANA
us-gaap:GeneralAndAdministrativeExpense █▇▆▆▇▅▅▄▃▃▃▂▂▃▃▃▂▂▂▂▂▂▂▂▂▂▁▁▁▁▁25.46220.67218.58216.96120.56516.02313.62510.6198.8319.6767.2365.3544.767.5197.46.6854.0665.4964.8714.3384.4184.8574.5194.713.7254.3722.8412.2431.3021.1421.136
us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest -40.269NANANA-31.82NANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:IncomeTaxExpenseBenefit 0.546NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:InterestExpense ▄▄0.0040.004NANA0.0060.0040.0030.00.00.00.2040.2230.176NANANANANANANANANANA0.00.00.0420.1570.1920.2410.2490.27
us-gaap:NetIncomeLoss ▁▃▂▅▃▄▁▃▄▄▅▅▂▆▆▆▆▆▆▆▆▆▆▆▇▇▇▇███-40.815-29.965-36.586-21.849-31.82-22.492-39.67-30.79-23.845-26.154-18.61-19.02-35.644-15.579-15.589-15.033-15.225-14.201-14.022-14.176-15.635-16.944-16.176-14.587-11.193-11.355-10.804-6.719-4.194-3.786-3.819
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▁█-40.815-29.965NA-21.849-31.82-22.492NA-30.79-23.845-26.154-18.611-19.02-35.644-15.579NANANANANANANANANANANANANANANANANA
us-gaap:NonoperatingIncomeExpense ▆▅▁▇▇█▇▇█▇▆▆▆-0.025-0.858-4.9371.0511.6732.6741.6931.882.1362.0180.8780.1780.154NA0.1790.1790.143NANANA0.0460.0550.0340.0270.021-0.177-2.712-0.282-0.462-0.131-0.265
us-gaap:OperatingExpenses ██▇▇▇▆▅▄▄▃▃▃▄▂▂▂▂▂▂▂▂▂▂▂▂▂▁▁▁▁▁81.58176.7172.60571.77573.94159.19448.44340.70531.66331.27921.0320.74337.34317.41217.18615.68615.36814.37214.20814.39915.68116.99916.39414.61711.21411.1788.0926.4373.7323.6553.554
us-gaap:OperatingIncomeLoss ▁▄▃▅▃▄▁▃▄▄▆▆▂▆▆▇▆▇▇▇▆▆▆▇▇▇█-40.244-29.107-31.649-22.9-33.493-25.166-41.363-32.67-25.981-28.172-19.489-19.198-35.798-15.867-15.768-15.212-15.368-14.239-14.075-14.237-15.681-16.999-16.21-14.617-11.214-11.178-8.092NANANANA
us-gaap:OtherNonoperatingIncomeExpense █▇▁███-0.132-1.134-5.5460.001-0.050.065NANA0.0NANANANANANANANANANANANANANANANANANANANANANA
us-gaap:ResearchAndDevelopmentExpense █████▆▅▅▄▄▂▂▂▂▂▂▂▂▂▂▂▂▂▂▂▂▁▁▁▁▁56.11956.03854.02354.81453.37643.17134.77930.08622.83221.60313.78411.69510.3399.8939.7869.0019.0688.8769.33710.06111.26312.14211.8759.9077.4896.8065.2514.1942.432.5132.418
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax ▇█▇█▇▆▂▂▂▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁41.33747.60340.95648.87540.44834.0287.088.0355.6823.1071.5411.5451.5451.5451.030.00.2520.1330.1330.1620.00.00.1840.00.00.00.00.00.00.00.0
us-gaap:Revenues ▇█▇█▇▆▂▂▂▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁41.33747.60340.95648.87540.44834.0287.088.0355.6823.1071.5411.5451.5451.5451.4180.4740.2520.1330.1330.1620.00.00.1840.00.00.00.00.00.00.00.0
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:Assets █▇▇▇▇▇▆▄▄▄▄▂▁▂▂▁▁▁▁▁▂▂▂▂▂▂▂▁838.492683.41707.846681.738732.41778.789597.409336.25361.396383.989409.041185.50889.715104.074120.88482.72694.72339.43651.25262.949100.023113.641127.662103.605116.032124.153135.87349.794NANANA
us-gaap:Liabilities █▆▆▆▆▇▅▃▃▃▃▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁727.418557.006570.092528.038570.242600.883445.214201.883201.231204.361208.34829.12825.1416.18819.64610.5229.58310.34710.0449.8179.0019.3618.9815.2655.2123.9586.5438.467NANANA
us-gaap:LiabilitiesAndStockholdersEquity █▇▇▇▇▇▆▄▄▄▄▂▁▂▂▁▁▁▁▁▂▂▂▂▂▂▂▁838.492683.41707.846681.738732.41778.789597.409336.25361.396383.989409.041185.50889.715104.074120.88482.72694.72339.43651.25262.949100.023113.641127.662103.605116.032124.153135.87349.794NANANA
us-gaap:StockholdersEquity ▆▆▆▇▇▇▇▆▇▇█▇▄▅▅▃▃▄▄▄▅▅▆▅▆▆▆▁111.074126.404137.754153.7162.168177.906152.195134.367160.165179.628200.693156.3864.57587.886101.238-3.77913.26829.08941.20853.13291.022104.28118.68198.34110.82120.195129.33-68.919NANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:AssetsCurrent ▇▇▇▇██▆▄▄▄▅▂▂▂▂▁▂▁▁▁▂▂▂▂▂▂▂▁616.492594.5618.703627.651681.762730.496556.169320.398350.248373.364405.514183.48687.612101.81118.55879.83491.69636.20347.82659.38296.14195.70996.74197.31693.746101.274134.69848.653NANANA
us-gaap:CashAndCashEquivalentsAtCarryingValue ▇▆▅▇▇█▅▂▄▆▃▂▂▂▃▂▂▂▂▂▃▂▂▂▂▃▅▂▃▁▁221.21159.111126.023204.281197.801245.479152.81647.226100.321160.14154.23946.39942.42643.04668.78930.9638.77722.87320.86532.54456.05852.94325.90826.06731.81577.732133.79246.59554.7121.8413.73
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents ▇▅▄▇▇█▅▂▄▅▂▂▂▂▂▁▂▁▁226.828164.729132.385210.643203.364251.042156.7150.77103.865163.68554.98347.14343.1743.7969.53332.07639.89323.98921.981NA57.174NANANANANANANANANANA
us-gaap:ReceivablesNetCurrent ▁▂▂▁▁▂█▁▁▁▄3.14731.26734.7135.0280.01215.0200.43.00.00.0100.0NANANA0.0NANANANANANANANANANANANANANANANA
us-gaap:PrepaidExpenseAndOtherAssetsCurrent █▇▆▅▅▄▃▂▂▁▂▂▂▂▂▂▂▂▁▁▁▁▁▁▁▁▁▁20.3818.34914.40312.7112.5418.6066.9344.6884.9582.162.8883.1073.7282.4113.2973.9152.9662.7081.9521.8361.5321.671.7331.1940.8561.0160.9062.058NANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:AssetsNoncurrent █▄▄▃▃▂▂▁▁▁▁▁▁▁▁▁▁▁▁▁▁▂▂▁▂▂▁▁222.088.9189.14354.08750.64848.29341.2415.85211.14810.6253.5272.0222.1032.2642.3262.8923.0273.2333.4263.5673.88217.93230.9216.28922.28622.8791.1751.141NANANA
us-gaap:PropertyPlantAndEquipmentGross NANANA19.867NANA13.63611.691NANA8.025NANANA6.046NANANA5.99NA5.6NANA5.223NANANA3.21NANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType drna:LabEquipmentNANANA9.867NANA9.1478.111NANA4.607NANANA4.41NANANA4.39NA4.161NANA3.209NANANA1.988NANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType drna:OfficeAndComputerEquipmentNANANA2.152NANA2.4251.29NANA1.021NANANA0.9NANANA0.864NA0.705NANA0.503NANANA0.253NANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:ConstructionInProgressNANANA5.917NANA0.2381.554NANA1.661NANANA0.0NANANANANANANANANANANANANANANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:FurnitureAndFixturesNANANA1.674NANA1.5690.479NANA0.479NANANA0.479NANANA0.479NA0.477NANA0.624NANANA0.299NANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:LeaseholdImprovementsNANANA0.257NANA0.2570.257NANA0.257NANANA0.257NANANA0.257NA0.257NANA0.887NANANA0.67NANANA
us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment NANANA7.021NANA6.566.183NANA5.307NANANA4.534NANANA3.756NA2.916NANA3.058NANANA2.333NANANA
us-gaap:PropertyPlantAndEquipmentNet NANANA12.8469.1357.57.0765.5084.9153.9712.7181.2121.2931.4511.5121.7041.8372.0422.2342.3732.6842.7152.5842.1651.8921.4730.9110.877NANANA
us-gaap:OperatingLeaseRightOfUseAsset █▇▇▄▄▄▄▁▁▁74.459.0360.84328.13629.48829.93230.1022.2242.6273.047NANANANANANANANANANANANANANANANANANANANANA
us-gaap:OtherAssetsNoncurrent ▃▇▆██▆▁▆▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁1.795.3895.1366.7436.4625.2980.1684.5760.0620.0630.0650.0660.0660.0690.070.0720.0740.0750.0760.0780.0820.1110.1880.243NANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:AccountsPayableCurrent █▇▅▅▅▄▄▃▄▃▃▃▃▂▃▄▃▃▃▃▂▁▂▁▁▁▁▂12.82911.2767.9017.2497.7646.4976.0773.4075.6364.9585.0133.5953.7572.0264.925.3924.1294.0854.3183.6572.6211.371.6371.2371.2151.0620.7151.7NANANA
us-gaap:ContractWithCustomerLiabilityCurrent ▆▅▅▇███▄▃▃▃▁160.2137.954138.537200.041221.343223.556212.25895.65978.07359.78468.8934.635NANA6.18NANANANANANANANANANANANANANANANA
us-gaap:LiabilitiesCurrent ▇▆▆▇███▄▄▃▃▂▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁207.65182.147177.938239.768258.926252.304241.735119.36195.87274.68894.05529.12816.23614.64316.64610.5229.58310.34710.0449.8179.0019.3618.9815.1595.1063.9586.5437.678NANANA
us-gaap:OperatingLeaseLiabilityCurrent NANANA2.4282.813.1643.358NANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:OtherAccruedLiabilitiesCurrent NANA2.6162.4753.268NA0.8780.929NANA0.312NANANA0.391NANANA0.433NA4.284NANA2.362NANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:LiabilitiesNoncurrent █▆▆▄▅▅▃▁▁▂▂519.768374.859392.154288.27311.316348.579203.47982.522105.359129.673114.293NA8.904NA3.09NANANANANANANANA0.1060.106NANA0.789NANANA
us-gaap:OtherLiabilitiesNoncurrent █▃▂▁▁▁▁3.5011.471.1740.6080.6080.5550.608NANANA0.0NANANANANANANANANANANANANANANANANANANANA
us-gaap:OperatingLeaseLiabilityNoncurrent NANANA19.1619.81920.51820.141NANANANANANANANANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:StockholdersEquity ▆▆▆▇▇▇▇▆▇▇█▇▄▅▅▃▃▄▄▄▅▅▆▅▆▆▆▁111.074126.404137.754153.7162.168177.906152.195134.367160.165179.628200.693156.3864.57587.886101.238-3.77913.26829.08941.20853.13291.022104.28118.68198.34110.82120.195129.33-68.919NANANA
us-gaap:CommonStockValue ███▇▇▇▇▇▇▇▇▆▅▅▅▂▂▂▂▂▂▂▂▃▂▂▂▁0.0080.0080.0080.0070.0070.0070.0070.0070.0070.0070.0070.0060.0050.0050.0050.0020.0020.0020.0020.0020.0020.0020.0020.0030.0020.0020.0020.001NANANA
us-gaap:AdditionalPaidInCapital █▇▇▆▅▅▃▁▁▁▁819.909794.424775.809755.17741.789725.707677.504620.009615.014610.632605.495NANANA417.037NANANANANANANANANANANANANANANANA
us-gaap:RetainedEarningsAccumulatedDeficit ▁▁▂▂▂▃▃▄▄▄▄▅▅▅▅▆▆▆▆▆▇▇▇▇████-708.843-668.028-638.063-601.477-579.628-547.808-525.316-485.646-454.856-431.011-404.809-386.198-367.179-331.535-315.804-300.215-285.182-269.957-255.756-241.734-196.243-180.608-163.663-133.404-118.814-107.814-96.267-85.465NANANA
us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue █▁13.63312.413NA10.5810.2068.527NA4.9953.8934.8272.2152.1481.7781.747NANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:NetCashProvidedByUsedInOperatingActivities ▅▂▁▁▁█▂▁▂▃▃▂▂▂▂▂158.837-26.7-47.303-57.009-41.66321.084-14.924-32.0-26.05572.28761.64-11.069-15.822-16.451-5.954-12.475NANANANANANANANANANA-6.446NANANA1.047
us-gaap:NetCashProvidedByUsedInInvestingActivities ▄█▆█▆▁█▆▆▇▄▅▇▆▇▇-108.60752.886-41.97861.502-11.864-266.5268.764-21.091-34.41136.269-113.787-93.98114.961-9.9240.1344.98NANANANANANANANANANANANANANANA
us-gaap:NetCashProvidedByUsedInFinancingActivities ▂▁▂▁▁▄▄▁▁▁▅█▁▁▄▁11.8696.15811.0232.7865.84639.76852.0960.00.6460.14659.987109.0230.2410.63243.277-0.322NANANANANANANANANANA93.799NANANA-0.987
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect ▆▅▁▄▂▇█▂▂█▄▄▄▃62.09932.344-78.2587.279-47.67894.332105.94-53.095-59.82108.7027.843.973-0.62-25.743NANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:DepreciationDepletionAndAmortization █▄▃▂▃▃▂▂▂▁▁▁▁▁1.6660.8210.6040.50.5310.5350.4240.30.2970.2420.1940.1870.1980.195NANANANANANANANANANANANANANANANANA
us-gaap:IncreaseDecreaseInAccountsPayable ▆█▅▄▆▅▆▂▅▅▄▄▆▁▄▆▄▄▅▅▆▄▄▄▄▅▄▄▅▄▄1.5283.2820.812-0.6391.0780.9571.876-1.6040.7311.0640.172-0.2261.732-2.895-0.4881.713-0.407-0.1920.6610.4031.251-0.267-0.1250.0220.1530.349-0.621-0.2430.8710.045-0.557
us-gaap:NetCashProvidedByUsedInOperatingActivities ▅▂▁▁▁█▂▁▂▃▃▂▂▂▂▂158.837-26.7-47.303-57.009-41.66321.084-14.924-32.0-26.05572.28761.64-11.069-15.822-16.451-5.954-12.475NANANANANANANANANANA-6.446NANANA1.047
us-gaap:NetIncomeLoss ▁▃▂▅▃▄▁▃▄▄▅▅▂▆▆▆▆▆▆▆▆▆▆▆▇▇▇▇███-40.815-29.965-36.586-21.849-31.82-22.492-39.67-30.79-23.845-26.154-18.61-19.02-35.644-15.579-15.589-15.033-15.225-14.201-14.022-14.176-15.635-16.944-16.176-14.587-11.193-11.355-10.804-6.719-4.194-3.786-3.819
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▁█-40.815-29.965NA-21.849-31.82-22.492NA-30.79-23.845-26.154-18.611-19.02-35.644-15.579NANANANANANANANANANANANANANANANANA
us-gaap:ShareBasedCompensation █▇▆▆▆▅▄▄▃▃▂▂▂▂▂▂▂▂▂▂▂▂▂▂▂▂▂▁▁▁▁13.63312.4139.59810.5810.2068.5275.1074.9953.8934.8272.2152.1481.7791.7471.7671.972.0252.0072.0982.2722.3582.3932.6612.0131.6072.4052.2120.3420.0930.0270.033
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:NetCashProvidedByUsedInInvestingActivities ▄█▆█▆▁█▆▆▇▄▅▇▆▇▇-108.60752.886-41.97861.502-11.864-266.5268.764-21.091-34.41136.269-113.787-93.98114.961-9.9240.1344.98NANANANANANANANANANANANANANANA
us-gaap:PaymentsToAcquirePropertyPlantAndEquipment █▆▇▇▄▃▂▃▃▄▁▁▁▁▁▁▁▁▁▁▁▂▁▂▁▂▁▁▁4.8453.3784.2534.1361.9781.381.0351.4581.5762.280.1140.0720.0390.1340.00.0750.00.0580.0740.0960.1390.3560.2051.0030.2020.6520.1560.2210.189NANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
us-gaap:NetCashProvidedByUsedInFinancingActivities ▂▁▂▁▁▄▄▁▁▁▅█▁▁▄▁11.8696.15811.0232.7865.84639.76852.0960.00.6460.14659.987109.0230.2410.63243.277-0.322NANANANANANANANANANA93.799NANANA-0.987
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value8000.08000.08000.07000.07000.07000.07000.07000.07000.07000.07000.06000.05000.05000.05000.02000.02000.02000.02000.02000.02000.02000.02000.02000.02000.03000.03000.02000.02000.02000.01000.0
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Weighted Average Number Of Diluted Shares Outstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding


Weighted
Period End2021-06-302021-03-312020-06-302020-03-31
Value77767472
Percentage of WeightedAverageNumberOfDilutedSharesOutstanding100.0100.0100.0100.0

Weighted Average Number Of Shares Outstanding Basic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic


Weighted
Period End2021-06-302021-03-312020-06-302020-03-31
Value77767472
Percentage of WeightedAverageNumberOfSharesOutstandingBasic100.0100.0100.0100.0

Weighted Average Number Of Share Outstanding Basic And Diluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted


Weighted
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-312015-09-302015-06-302015-03-312014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value7474726868685452512020202020202018171717100.0281030.0280950.027952
Percentage of WeightedAverageNumberOfShareOutstandingBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount


Antidilutive
Period End2021-03-312020-03-312019-03-312018-03-312017-03-31
Value16151172596147
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount100.0100.0100.0100.0100.0

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities

us-gaap:EmployeeStockOption


Antidilutive
Period End2021-03-312020-03-312019-03-312018-03-312017-03-312016-03-312015-09-302014-09-30
Value15141171716.0493464.8885224.3735943.323387
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount92.395.5100.098.80.10.00.00.0

us-gaap:RestrictedStock


Antidilutive
Period End2021-03-312020-03-312019-03-312017-03-312016-03-312015-09-302015-06-302015-03-312014-09-302014-06-302014-03-31
Value1.2883940.70370.00.010.0291560.0636370.0727720.0841620.1044850.1098590.064163
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount7.74.50.00.00.00.00.00.00.00.00.0

Earnings Per Share Basic

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareBasic


Earnings
Period End2021-06-302021-03-312020-06-302020-03-31
Value-0.53-0.39-0.43-0.31
Percentage of EarningsPerShareBasic100.0100.0100.0100.0

Earnings Per Share Diluted

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareDiluted


Earnings
Period End2021-06-302021-03-312020-06-302020-03-31
Value-0.53-0.39-0.43-0.31
Percentage of EarningsPerShareDiluted100.0100.0100.0100.0

Earnings Per Share Basic And Diluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:EarningsPerShareBasicAndDiluted


Earnings
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-0.49-0.29-0.43-0.31-0.58-0.45-0.35-0.38-0.29-0.35-0.68-0.3-0.9-0.92-1.15-0.68-0.68-0.68-0.75-0.76-0.76-0.82-0.86-0.79-0.82-0.63-0.64-1.02-199.91-161.55-171.13-172.8
Percentage of EarningsPerShareBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Comprehensive Income Net Of Tax

us-gaap:ComprehensiveIncomeNetOfTax

us-gaap:ComprehensiveIncomeNetOfTax


Comprehensive
Period End2020-09-302019-09-302018-09-30
Value-21849000.0-30793000.0-19020000.0
Percentage of ComprehensiveIncomeNetOfTax100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-44.7-383.2-1231.1

General And Administrative Expense

us-gaap:GeneralAndAdministrativeExpense

us-gaap:GeneralAndAdministrativeExpense


General
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value25201816201613108.8319.6767.2365.3544.767.5197.46.6854.0665.4964.8714.3384.6564.4844.4184.8574.5195.4454.713.7254.3722.8412.2431.3021.1421.136
Percentage of GeneralAndAdministrativeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax61.643.40.034.750.847.1192.4132.2155.4311.4469.6346.5308.1486.7718.40.01613.54132.33662.42677.80.00.00.00.02456.00.00.00.00.00.00.00.00.00.0

Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest


Income
Period End2021-06-302020-06-30
Value-40269000.0-31820000.0
Percentage of IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-97.4-78.7

Income Tax Expense Benefit

us-gaap:IncomeTaxExpenseBenefit

us-gaap:IncomeTaxExpenseBenefit


Income
Period End2021-06-30
Value546000.0
Percentage of IncomeTaxExpenseBenefit100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.3

Interest Expense

us-gaap:InterestExpense

us-gaap:InterestExpense


Interest
Period End2021-06-302021-03-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value4000.04000.06000.04000.03000.0000204000.0223000.0176000.00042000.0157000.0192000.0241000.0249000.0270000.0
Percentage of InterestExpense100.0100.0100.0100.0100.00.00.00.0100.0100.0100.00.00.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.00.00.00.00.00.00.00.013.214.411.40.00.00.00.00.00.00.00.0

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-40815000.0-29965000.0-36586000.0-21849000.0-31820000.0-22492000.0-39670000.0-30790000.0-23845000.0-26154000.0-18610000.0-19020000.0-35644000.0-15579000.0-15589000.0-15033000.0-15225000.0-14201000.0-14022000.0-14176000.0-15622000.0-15693000.0-15635000.0-16944000.0-16176000.0-14084000.0-14587000.0-11193000.0-11355000.0-10804000.0-6719000.0-4194000.0-3786000.0-3819000.0
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-98.7-62.90.0-44.7-78.7-66.1-560.3-383.2-419.7-841.8-1207.7-1231.1-2307.1-1008.3-1513.50.0-6041.7-10677.4-10542.9-8750.60.00.00.00.0-8791.30.00.00.00.00.00.00.00.00.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-40815000.0-29965000.0-21849000.0-31820000.0-22492000.0-30790000.0-23845000.0-26154000.0-18611000.0-19020000.0-35644000.0-15579000.0
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-98.7-62.9-44.7-78.7-66.1-383.2-419.7-841.8-1207.7-1231.1-2307.1-1008.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.0

Nonoperating Income Expense

us-gaap:NonoperatingIncomeExpense

us-gaap:NonoperatingIncomeExpense


Nonoperating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-312017-09-302017-06-302015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-25000.0-858000.0-4937000.01051000.01673000.02674000.01693000.01880000.02136000.02018000.0878000.0178000.0154000.0179000.0179000.0143000.046000.055000.034000.053000.027000.021000.0-177000.0-2712000.0-282000.0-462000.0-131000.0-265000.0
Percentage of NonoperatingIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-0.1-1.80.02.24.17.923.923.437.665.057.011.510.017.40.056.70.00.018.50.00.00.00.00.00.00.00.00.0

Operating Expenses

us-gaap:OperatingExpenses

us-gaap:OperatingExpenses


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value81767271735948403131212037171715151414141515151616141411118.0926.4373.7323.6553.554
Percentage of OperatingExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax197.4161.10.0146.9182.8174.0684.2506.6557.31006.71364.71342.62417.01127.01668.50.06098.410806.010682.78888.30.00.00.00.08909.80.00.00.00.00.00.00.00.00.0

Operating Income Loss

us-gaap:OperatingIncomeLoss

us-gaap:OperatingIncomeLoss


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-31
Value-40244000.0-29107000.0-31649000.0-22900000.0-33493000.0-25166000.0-41363000.0-32670000.0-25981000.0-28172000.0-19489000.0-19198000.0-35798000.0-15867000.0-15768000.0-15212000.0-15368000.0-14239000.0-14075000.0-14237000.0-15688000.0-15748000.0-15681000.0-16999000.0-16210000.0-14137000.0-14617000.0-11214000.0-11178000.0-8092000.0
Percentage of OperatingIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-97.4-61.10.0-46.9-82.8-74.0-584.2-406.6-457.3-906.7-1264.7-1242.6-2317.0-1027.0-1530.90.0-6098.4-10706.0-10582.7-8788.30.00.00.00.0-8809.80.00.00.00.00.0

Other Nonoperating Income Expense

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:OtherNonoperatingIncomeExpense


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-06-30
Value-132000.0-1134000.0-5546000.01000.0-50000.065000.00
Percentage of OtherNonoperatingIncomeExpense100.0100.0100.0100.0100.0100.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-0.3-2.40.00.0-0.10.20.0

Research And Development Expense

us-gaap:ResearchAndDevelopmentExpense

us-gaap:ResearchAndDevelopmentExpense


Research
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value565654545343343022211311109.8939.7869.0019.0688.8769.3371011111112118.6929.9077.4896.8065.2514.1942.432.5132.418
Percentage of ResearchAndDevelopmentExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax135.8117.70.0112.2132.0126.9491.2374.4401.8695.3894.5757.0669.2640.3950.10.03598.46673.77020.36210.50.00.00.00.06453.80.00.00.00.00.00.00.00.00.0

Revenue From Contract With Customer Excluding Assessed Tax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value4147404840347.088.0355.6823.1071.5411.5451.5451.5451.030.00.2520.1330.1330.1620.00.00.1840.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.00.00.0100.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.00.00.0100.00.00.00.00.00.00.00.00.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:TypeOfArrangement

drna:AlexionCollaborativeResearchAndLicenseAgreement


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2.3167.1897.757117.0632.11.4511.4511.0820.4
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.615.118.923.217.56.220.518.119.012.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.615.118.923.217.56.220.518.119.012.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:AlexionCollaborativeResearchAndLicenseAgreement100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

drna:AlexionCollaborativeResearchAndLicenseAgreementAmendment


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value0.1710.6281.0222.2811.2710.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.41.32.54.73.11.8
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.41.32.54.73.11.8
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:AlexionCollaborativeResearchAndLicenseAgreementAmendment100.0100.0100.0100.0100.0100.0

drna:AlexionCollaborativeResearchAndLicenseAgreementAndAmendment


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-30
Value2.4877.8178.779137.0632.7621.4511.451
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.016.421.427.917.58.120.518.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.016.421.427.917.58.120.518.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:AlexionCollaborativeResearchAndLicenseAgreementAndAmendment100.0100.0100.0100.0100.0100.0100.0100.0

drna:BoehringerIngelheimAgreement


Revenue
Period End2021-06-302020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value3.1810.2630.9250.7740.7720.00.51.31.4
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax7.70.61.91.92.30.06.222.945.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax7.70.61.91.92.30.06.222.945.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:BoehringerIngelheimAgreement100.0100.0100.0100.0100.00.0100.0100.0100.0

drna:LillyCollaborationAndLicenseAgreement


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value147.56310129.4879.64.85.22.60.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax35.615.925.424.723.528.267.864.745.816.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax35.615.925.424.723.528.267.864.745.816.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:LillyCollaborationAndLicenseAgreement100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

drna:NovoCollaborationAgreement


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-06-30
Value6.76.6126.273.5522.4471.60.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax16.213.915.37.36.04.70.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax16.213.915.37.36.04.70.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:NovoCollaborationAgreement100.0100.0100.0100.0100.0100.00.0

drna:RocheCollaborationAgreement


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-06-30
Value1425151820190.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax34.453.837.338.251.156.70.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax34.453.837.338.251.156.70.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax drna:RocheCollaborationAgreement100.0100.0100.0100.0100.0100.00.0

Revenues

us-gaap:Revenues

us-gaap:Revenues


Revenues
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312015-09-302015-06-302014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value4147404840347.088.0355.6823.1071.5411.5451.5451.5451.4180.4740.2520.1330.1330.1620.00.00.1840.00.00.00.00.00.00.00.0
Percentage of Revenues100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.0100.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0137.70.0100.0100.0100.0100.00.00.0100.00.00.00.00.00.00.00.00.0

Assets

us-gaap:Assets

us-gaap:Assets


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value83868370768173277859733636138340918589104120829439516274851001131279210311612413549
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Liabilities

us-gaap:Liabilities

us-gaap:Liabilities


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value72755757052857060044520120120420829251619109.58310109.8179.3657.3649.0019.3618.9816.0175.2655.2123.9586.5438.467
Percentage of Liabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets86.881.580.577.577.977.274.560.055.753.250.915.728.015.616.312.710.126.219.615.612.68.69.08.27.06.55.14.53.24.817.0

Liabilities And Stockholders Equity

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:LiabilitiesAndStockholdersEquity


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value83868370768173277859733636138340918589104120829439516274851001131279210311612413549
Percentage of LiabilitiesAndStockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value1111261371531621771521341601792001566487101-3.779132941536478911041188698110120129-68.919-64.719-50.633
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets13.218.519.522.522.122.825.540.044.346.849.184.372.084.483.7-4.614.073.880.484.487.491.491.091.893.093.594.995.596.895.2-138.40.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value81979477575574172567762061561060554243141941729628723116
Percentage of StockholdersEquity738.2628.5563.2491.3457.4407.9445.2461.4384.0339.9301.7347.0668.6477.2411.9720.6315.6235.7-24.0
Percentage of Assets97.8116.2109.6110.8101.393.2113.4184.4170.2159.0148.0292.5481.2403.0345.0579.4287.2223.733.2
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value0.0080.0080.0080.0070.0070.0070.0070.0070.0070.0070.0070.0060.0050.0050.0050.0020.0020.0030.0010.0010.001
Percentage of StockholdersEquity0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0-0.0-0.0-0.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value-708.843-668.028-638.063-601.477-579.628-547.808-525.316-485.646-454.856-431.011-404.809-386.198-367.179-331.535-315.804-255.756-196.243-133.404-85.465-64.72-50.634
Percentage of StockholdersEquity-638.2-528.5-463.2-391.3-357.4-307.9-345.2-361.4-284.0-239.9-201.7-247.0-568.6-377.2-311.9-620.6-215.6-135.7124.0100.0100.0
Percentage of Assets-84.5-97.7-90.1-88.2-79.1-70.3-87.9-144.4-125.9-112.2-99.0-208.2-409.3-318.6-261.2-499.0-196.2-128.8-171.60.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Assets Current

us-gaap:AssetsCurrent

us-gaap:AssetsCurrent


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value616594618627681730556320350373405183871011187991364759708196959689979310113448
Percentage of AssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets73.587.087.492.193.193.893.195.396.997.299.198.997.797.898.196.596.891.893.394.395.195.696.184.275.896.193.980.881.699.197.7

Cash And Cash Equivalents At Carrying Value

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashAndCashEquivalentsAtCarryingValue


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-31
Value221159126204197245152471001605446424368303822203229275652252226317713346541.8413.733.6722
Percentage of CashAndCashEquivalentsAtCarryingValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets26.423.317.830.027.031.525.614.027.841.713.325.047.341.456.937.440.958.040.751.739.332.356.046.620.324.425.227.462.698.593.60.00.00.00.00.0

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312015-12-31
Value2261641322102032511565010316354474343693239232157
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets27.124.118.730.927.832.226.215.128.742.613.425.448.142.157.538.842.160.842.957.2

Receivables Net Current

us-gaap:ReceivablesNetCurrent

us-gaap:ReceivablesNetCurrent


Receivables
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value3.14731345.0280.012152003.00.00.01000.0
Percentage of ReceivablesNetCurrent100.0100.0100.0100.0100.0100.0100.0100.00.00.0100.00.0
Percentage of Assets0.44.64.90.70.01.933.50.90.00.024.40.0

Prepaid Expense And Other Assets Current

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent


Prepaid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value20181412128.6066.9344.6884.9582.162.8883.1073.7282.4113.2973.9152.9662.7081.9521.8361.4821.1671.5321.671.7331.4161.1940.8561.0160.9062.058
Percentage of PrepaidExpenseAndOtherAssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.42.72.01.91.71.11.21.41.40.60.71.74.22.32.74.73.16.93.82.92.01.41.51.51.41.51.20.70.80.74.1

Assets Noncurrent

us-gaap:AssetsNoncurrent

us-gaap:AssetsNoncurrent


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value2228889545048411511103.5272.0222.1032.2642.3262.8923.0273.2333.4263.5673.6613.7323.88217303.666.28922221.1751.141
Percentage of AssetsNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets26.513.012.67.96.96.26.94.73.12.80.91.12.32.21.93.53.28.26.75.74.94.43.915.824.23.96.119.218.40.92.3

Property Plant And Equipment Gross

us-gaap:PropertyPlantAndEquipmentGross

us-gaap:PropertyPlantAndEquipmentGross


Property
Period End2020-09-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value1913118.0256.0465.995.65.2233.21
Percentage of PropertyPlantAndEquipmentGross100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.92.33.52.05.011.75.65.06.4

us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType

drna:LabEquipment


Property
Period End2020-09-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value9.8679.1478.1114.6074.414.394.1613.2091.988
Percentage of PropertyPlantAndEquipmentGross49.767.169.457.472.973.374.361.461.9
Percentage of Assets1.41.52.41.13.68.64.23.14.0
Percentage of Assets drna:LabEquipment0.00.00.00.00.00.00.00.00.0

drna:OfficeAndComputerEquipment


Property
Period End2020-09-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value2.1522.4251.291.0210.90.8640.7050.5030.253
Percentage of PropertyPlantAndEquipmentGross10.817.811.012.714.914.412.69.67.9
Percentage of Assets0.30.40.40.20.71.70.70.50.5
Percentage of Assets drna:OfficeAndComputerEquipment0.00.00.00.00.00.00.00.00.0

us-gaap:ConstructionInProgress


Property
Period End2020-09-302019-12-312019-09-302018-12-312017-12-31
Value5.9170.2381.5541.6610.0
Percentage of PropertyPlantAndEquipmentGross29.81.713.320.70.0
Percentage of Assets0.90.00.50.40.0
Percentage of Assets us-gaap:ConstructionInProgress0.00.00.00.00.0

us-gaap:FurnitureAndFixtures


Property
Period End2020-09-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value1.6741.5690.4790.4790.4790.4790.4770.6240.299
Percentage of PropertyPlantAndEquipmentGross8.411.54.16.07.98.08.511.99.3
Percentage of Assets0.20.30.10.10.40.90.50.60.6
Percentage of Assets us-gaap:FurnitureAndFixtures0.00.00.00.00.00.00.00.00.0

us-gaap:LeaseholdImprovements


Property
Period End2020-09-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value0.2570.2570.2570.2570.2570.2570.2570.8870.67
Percentage of PropertyPlantAndEquipmentGross1.31.92.23.24.34.34.617.020.9
Percentage of Assets0.00.00.10.10.20.50.30.91.3
Percentage of Assets us-gaap:LeaseholdImprovements0.00.00.00.00.00.00.00.00.0

Accumulated Depreciation Depletion And Amortization Property Plant And Equipment

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment


Accumulated
Period End2020-09-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value7021000.06560000.06183000.05307000.04534000.03756000.02916000.03058000.02333000.0
Percentage of AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.01.11.81.33.87.32.93.04.7

Property Plant And Equipment Net

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:PropertyPlantAndEquipmentNet


Property
Period End2020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value129.1357.57.0765.5084.9153.9712.7181.2121.2931.4511.5121.7041.8372.0422.2342.3732.4662.5362.6842.7152.5842.3272.1651.8921.4730.9110.877
Percentage of PropertyPlantAndEquipmentNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.91.21.01.21.61.41.00.70.71.41.41.32.11.95.24.43.83.33.02.72.42.02.52.11.61.20.71.8

Operating Lease Right Of Use Asset

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:OperatingLeaseRightOfUseAsset


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value745960282929302.2242.6273.047
Percentage of OperatingLeaseRightOfUseAsset100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets8.98.68.64.14.03.85.00.70.70.8

us-gaap:OperatingLeaseRightOfUseAsset us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:SeventyFiveHaydenAvenue


Operating
Period End2021-06-30
Value17
Percentage of OperatingLeaseRightOfUseAsset23.1
Percentage of Assets2.1
Percentage of Assets drna:SeventyFiveHaydenAvenue0.0

Other Assets Noncurrent

us-gaap:OtherAssetsNoncurrent

us-gaap:OtherAssetsNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value1790000.05389000.05136000.06743000.06462000.05298000.0168000.04576000.062000.063000.065000.066000.066000.069000.070000.072000.074000.075000.076000.078000.079000.080000.082000.0111000.0188000.0217000.0243000.0
Percentage of OtherAssetsNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.20.80.71.00.90.70.01.40.00.00.00.00.10.10.10.10.10.20.10.10.10.10.10.10.10.20.2

Accounts Payable Current

us-gaap:AccountsPayableCurrent

us-gaap:AccountsPayableCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value12117.9017.2497.7646.4976.0773.4075.6364.9585.0133.5953.7572.0264.925.3924.1294.0854.3183.6573.2232.4382.6211.371.6371.7621.2371.2151.0620.7151.7
Percentage of AccountsPayableCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.51.61.11.11.10.81.01.01.61.31.21.94.21.94.16.54.410.48.45.84.32.82.61.21.31.91.21.00.90.53.4

Contract With Customer Liability Current

us-gaap:ContractWithCustomerLiabilityCurrent

us-gaap:ContractWithCustomerLiabilityCurrent


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302017-12-31
Value160137138200221223212957859684.6356.18
Percentage of ContractWithCustomerLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets19.120.219.629.330.228.735.528.421.615.616.82.55.1

us-gaap:ContractWithCustomerLiabilityCurrent us-gaap:TypeOfArrangement

drna:AlexionCollaborativeResearchAndLicenseAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value6.9517.7869.21617413627
Percentage of ContractWithCustomerLiabilityCurrent4.35.66.78.918.516.513.1
Percentage of Assets0.81.11.32.65.64.74.7
Percentage of Assets drna:AlexionCollaborativeResearchAndLicenseAgreement0.00.00.00.00.00.00.0

drna:AlexionCollaborativeResearchAndLicenseAgreementAmendment


Contract
Period End2021-06-302020-12-312020-09-302019-12-31
Value1.3039.4647.7471.197
Percentage of ContractWithCustomerLiabilityCurrent0.86.83.90.6
Percentage of Assets0.21.31.10.2
Percentage of Assets drna:AlexionCollaborativeResearchAndLicenseAgreementAmendment0.00.00.00.0

drna:AlexionCollaborativeResearchAndLicenseAgreementAndAmendment


Contract
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value8.2547.786182527
Percentage of ContractWithCustomerLiabilityCurrent5.25.613.512.813.1
Percentage of Assets1.01.12.63.74.7
Percentage of Assets drna:AlexionCollaborativeResearchAndLicenseAgreementAndAmendment0.00.00.00.00.0

drna:BoehringerIngelheimAgreement


Contract
Period End2020-09-302020-06-302019-12-312019-06-302017-10-27
Value0.1061.0312.2730.51.8
Percentage of ContractWithCustomerLiabilityCurrent0.10.51.10.60.0
Percentage of Assets0.00.10.40.10.0
Percentage of Assets drna:BoehringerIngelheimAgreement0.00.00.00.00.0

drna:LillyCollaborationAndLicenseAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value5344405159456369624654
Percentage of ContractWithCustomerLiabilityCurrent33.132.029.025.527.120.329.872.379.577.178.4
Percentage of Assets6.36.55.77.58.25.810.620.617.212.013.2
Percentage of Assets drna:LillyCollaborationAndLicenseAgreement0.00.00.00.00.00.00.00.00.00.00.0

drna:NovoCollaborationAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value3629303939330.8
Percentage of ContractWithCustomerLiabilityCurrent23.021.521.819.818.014.80.4
Percentage of Assets4.44.34.35.85.54.30.1
Percentage of Assets drna:NovoCollaborationAgreement0.00.00.00.00.00.00.0

drna:RocheCollaborationAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value6256498379106118
Percentage of ContractWithCustomerLiabilityCurrent38.740.935.741.835.947.755.6
Percentage of Assets7.48.27.012.310.913.719.8
Percentage of Assets drna:RocheCollaborationAgreement0.00.00.00.00.00.00.0

Liabilities Current

us-gaap:LiabilitiesCurrent

us-gaap:LiabilitiesCurrent


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value20718217723925825224111995749429161416109.58310109.8179.3657.3649.0019.3618.9816.0175.1595.1063.9586.5437.678
Percentage of LiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets24.826.725.135.235.432.440.535.526.519.523.015.718.114.113.812.710.126.219.615.612.68.69.08.27.06.55.04.43.24.815.4

Operating Lease Liability Current

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OperatingLeaseLiabilityCurrent


Operating
Period End2020-09-302020-06-302020-03-312019-12-31
Value2428000.02810000.03164000.03358000.0
Percentage of OperatingLeaseLiabilityCurrent100.0100.0100.0100.0
Percentage of Assets0.40.40.40.6

Other Accrued Liabilities Current

us-gaap:OtherAccruedLiabilitiesCurrent

us-gaap:OtherAccruedLiabilitiesCurrent


Other
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-31
Value2616000.02475000.03268000.0878000.0929000.0312000.0391000.0433000.04284000.02362000.0
Percentage of OtherAccruedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.40.40.40.10.30.10.30.84.32.3

Liabilities Noncurrent

us-gaap:LiabilitiesNoncurrent

us-gaap:LiabilitiesNoncurrent


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-06-302017-12-312014-12-312014-09-302013-12-31
Value519374392288311348203821051291148.9043.090.1060.1060.789
Percentage of LiabilitiesNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets62.054.955.442.342.544.834.124.529.233.827.99.92.60.10.11.6

Other Liabilities Noncurrent

us-gaap:OtherLiabilitiesNoncurrent

us-gaap:OtherLiabilitiesNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-12-31
Value3501000.01470000.01174000.0608000.0608000.0555000.0608000.00
Percentage of OtherLiabilitiesNoncurrent100.0100.0100.0100.0100.0100.0100.00.0
Percentage of Assets0.40.20.20.10.10.10.10.0

Operating Lease Liability Noncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent


Operating
Period End2020-09-302020-06-302020-03-312019-12-31
Value19192020
Percentage of OperatingLeaseLiabilityNoncurrent100.0100.0100.0100.0
Percentage of Assets2.82.72.63.4

Operating Lease Liability

us-gaap:OperatingLeaseLiability

us-gaap:OperatingLeaseLiability


Operating
Period End2020-12-312019-12-312019-09-302019-06-302019-03-31
Value51232.2552.6833.128
Percentage of OperatingLeaseLiability100.0100.0100.0100.0100.0
Percentage of Assets7.34.00.70.70.8

us-gaap:OperatingLeaseLiability us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:SeventyFiveHaydenAvenue


Operating
Period End2021-06-30
Value15
Percentage of OperatingLeaseLiability0.0
Percentage of Assets1.8
Percentage of Assets drna:SeventyFiveHaydenAvenue0.0

Lessee Operating Lease Liability Payments Due

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue


Lessee
Period End2020-12-312019-12-312019-09-302019-06-302019-03-312014-12-01
Value71312.4292.9243.439.6
Percentage of LesseeOperatingLeaseLiabilityPaymentsDue100.0100.0100.0100.0100.0100.0
Percentage of Assets10.15.30.70.80.90.0

Lessee Operating Lease Liability Undiscounted Excess Amount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount


Lessee
Period End2020-12-31
Value19
Percentage of LesseeOperatingLeaseLiabilityUndiscountedExcessAmount100.0
Percentage of Assets2.8

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value1111261371531621771521341601792001566487101-3.779132941536478911041188698110120129-68.919-64.719-50.633
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets13.218.519.522.522.122.825.540.044.346.849.184.372.084.483.7-4.614.073.880.484.487.491.491.091.893.093.594.995.596.895.2-138.40.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value81979477575574172567762061561060554243141941729628723116
Percentage of StockholdersEquity738.2628.5563.2491.3457.4407.9445.2461.4384.0339.9301.7347.0668.6477.2411.9720.6315.6235.7-24.0
Percentage of Assets97.8116.2109.6110.8101.393.2113.4184.4170.2159.0148.0292.5481.2403.0345.0579.4287.2223.733.2
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value0.0080.0080.0080.0070.0070.0070.0070.0070.0070.0070.0070.0060.0050.0050.0050.0020.0020.0030.0010.0010.001
Percentage of StockholdersEquity0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0-0.0-0.0-0.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value-708.843-668.028-638.063-601.477-579.628-547.808-525.316-485.646-454.856-431.011-404.809-386.198-367.179-331.535-315.804-255.756-196.243-133.404-85.465-64.72-50.634
Percentage of StockholdersEquity-638.2-528.5-463.2-391.3-357.4-307.9-345.2-361.4-284.0-239.9-201.7-247.0-568.6-377.2-311.9-620.6-215.6-135.7124.0100.0100.0
Percentage of Assets-84.5-97.7-90.1-88.2-79.1-70.3-87.9-144.4-125.9-112.2-99.0-208.2-409.3-318.6-261.2-499.0-196.2-128.8-171.60.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value8000.08000.08000.07000.07000.07000.07000.07000.07000.07000.07000.06000.05000.05000.05000.02000.02000.02000.02000.02000.02000.02000.02000.02000.02000.03000.03000.02000.02000.02000.01000.0
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Additional Paid In Capital

us-gaap:AdditionalPaidInCapital

us-gaap:AdditionalPaidInCapital


Additional
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value819794775755741725677620615610605417
Percentage of AdditionalPaidInCapital100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets97.8116.2109.6110.8101.393.2113.4184.4170.2159.0148.0345.0

Retained Earnings Accumulated Deficit

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:RetainedEarningsAccumulatedDeficit


Retained
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value-708840000.0-668030000.0-638060000.0-601480000.0-579630000.0-547810000.0-525320000.0-485650000.0-454860000.0-431010000.0-404810000.0-386200000.0-367180000.0-331540000.0-315800000.0-300220000.0-285180000.0-269960000.0-255760000.0-241730000.0-227560000.0-211940000.0-196240000.0-180610000.0-163660000.0-147490000.0-133400000.0-118810000.0-107810000.0-96267000.0-85465000.0
Percentage of RetainedEarningsAccumulatedDeficit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets-84.5-97.7-90.1-88.2-79.1-70.3-87.9-144.4-125.9-112.2-99.0-208.2-409.3-318.6-261.2-362.9-301.1-684.5-499.0-384.0-306.1-247.8-196.2-158.9-128.2-159.0-128.8-102.4-86.8-70.9-171.6

Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue


Adjustments
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value131210108.5274.9953.8934.8272.2152.1481.7781.747
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Adjustments
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value131210108.5274.9953.8934.7842.2152.1481.7781.747
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.099.1100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-03-312013-03-31
Value158-26.7-47.303-57.009-41.66321-14.924-32.0-26.0557261-11.069-15.822-16.451-5.954-12.475-6.4461.047
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax384.2-56.1-115.5-116.6-103.0943.6-210.8-398.3-458.62326.64000.0-716.4-1024.1-1064.8-578.10.00.00.0

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-108.60752-41.97861-11.864-266.5268-21.091-34.41136-113.787-93.98114-9.9240.1344.98
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-262.7111.1-102.5125.8-29.3-783.2971.2-262.5-605.61167.3-7384.0-6082.9968.3-642.313.00.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-03-312013-03-31
Value116.158112.7865.84639520.00.6460.146591090.2410.63243-0.32293-0.987
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax28.712.926.95.714.5116.9735.80.011.44.73892.77056.515.640.94201.70.00.00.0

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value6232-78.2587.279-47.67894105-53.095-59.821087.843.973-0.62-25.743
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax150.267.9-191.114.9-117.9277.21496.3-660.8-1052.83498.6508.8257.2-40.1-1666.2

Depreciation Depletion And Amortization

us-gaap:DepreciationDepletionAndAmortization

us-gaap:DepreciationDepletionAndAmortization


Depreciation
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value1666000.0821000.0604000.0500000.0531000.0535000.0424000.0300000.0297000.0242000.0194000.0187000.0198000.0195000.0
Percentage of DepreciationDepletionAndAmortization100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Increase Decrease In Accounts Payable

us-gaap:IncreaseDecreaseInAccountsPayable

us-gaap:IncreaseDecreaseInAccountsPayable


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value1528000.03282000.0812000.0-639000.01078000.0957000.01876000.0-1604000.0731000.01064000.0172000.0-226000.01732000.0-2895000.0-488000.01713000.0-407000.0-192000.0661000.0403000.0807000.0-227000.01251000.0-267000.0-125000.0525000.022000.0153000.0349000.0-621000.0-243000.0871000.045000.0-557000.0
Percentage of IncreaseDecreaseInAccountsPayable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-03-312013-03-31
Value158-26.7-47.303-57.009-41.66321-14.924-32.0-26.0557261-11.069-15.822-16.451-5.954-12.475-6.4461.047
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax384.2-56.1-115.5-116.6-103.0943.6-210.8-398.3-458.62326.64000.0-716.4-1024.1-1064.8-578.10.00.00.0

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-40815000.0-29965000.0-36586000.0-21849000.0-31820000.0-22492000.0-39670000.0-30790000.0-23845000.0-26154000.0-18610000.0-19020000.0-35644000.0-15579000.0-15589000.0-15033000.0-15225000.0-14201000.0-14022000.0-14176000.0-15622000.0-15693000.0-15635000.0-16944000.0-16176000.0-14084000.0-14587000.0-11193000.0-11355000.0-10804000.0-6719000.0-4194000.0-3786000.0-3819000.0
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-98.7-62.9-89.3-44.7-78.7-66.1-560.3-383.2-419.7-841.8-1207.7-1231.1-2307.1-1008.3-1513.50.0-6041.7-10677.4-10542.9-8750.60.00.00.00.0-8791.30.00.00.00.00.00.00.00.00.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-40815000.0-29965000.0-21849000.0-31820000.0-22492000.0-30790000.0-23845000.0-26154000.0-18611000.0-19020000.0-35644000.0-15579000.0
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-98.7-62.9-44.7-78.7-66.1-383.2-419.7-841.8-1207.7-1231.1-2307.1-1008.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.0

Share Based Compensation

us-gaap:ShareBasedCompensation

us-gaap:ShareBasedCompensation


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value13129.59810108.5275.1074.9953.8934.8272.2152.1481.7791.7471.7671.972.0252.0072.0982.2722.412.3852.3582.3932.6612.322.0131.6072.4052.2120.3420.0930.0270.033
Percentage of ShareBasedCompensation100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ShareBasedCompensation us-gaap:IncomeStatementLocation

us-gaap:GeneralAndAdministrativeExpense


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-31
Value6.495.9794.5924.315.6284.2242.6722.7761.9922.9691.4281.431.0280.941.0471.0711.0531.0631.0951.1091.2841.21
Percentage of ShareBasedCompensation47.648.247.840.755.149.552.355.651.261.564.566.657.853.859.354.452.053.052.248.853.350.7

us-gaap:ResearchAndDevelopmentExpense


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-31
Value7.1436.4345.0066.274.5784.3032.4352.2191.9011.8580.7870.7180.7510.8070.720.8990.9720.9441.0031.1631.1261.175
Percentage of ShareBasedCompensation52.451.852.259.344.950.547.744.448.838.535.533.442.246.240.745.648.047.047.851.246.749.3

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-108.60752-41.97861-11.864-266.5268-21.091-34.41136-113.787-93.98114-9.9240.1344.98
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-262.7111.1-102.5125.8-29.3-783.2971.2-262.5-605.61167.3-7384.0-6082.9968.3-642.313.00.0

Payments To Acquire Property Plant And Equipment

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-30
Value4.8453.3784.2534.1361.9781.381.0351.4581.5762.280.1140.0720.0390.1340.00.0750.00.0580.0740.0960.1520.1270.1390.3560.2050.4341.0030.2020.6520.1560.2210.189
Percentage of PaymentsToAcquirePropertyPlantAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-03-312013-03-31
Value116.158112.7865.84639520.00.6460.146591090.2410.63243-0.32293-0.987
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax28.712.926.95.714.5116.9735.80.011.44.73892.77056.515.640.94201.70.00.00.0

Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice


Share
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312013-09-24
Value14.6611.389.368.5810.812.2411.283.4245.16
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0100.0100.0

Unrecognized Tax Benefits

us-gaap:UnrecognizedTaxBenefits

us-gaap:UnrecognizedTaxBenefits


Unrecognized
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Value5468000.03040000.01631000.01451000.01210000.01430000.01216000.0865000.0563000.0
Percentage of UnrecognizedTaxBenefits100.0100.0100.0100.0100.0100.0100.0100.0100.0

Deferred Tax Assets Valuation Allowance

us-gaap:DeferredTaxAssetsValuationAllowance

us-gaap:DeferredTaxAssetsValuationAllowance


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value12975364247484930
Percentage of DeferredTaxAssetsValuationAllowance100.0100.0100.0100.0100.0100.0100.0100.0

drna:AggregateSalesMilestonesReceivableExpense us-gaap:TypeOfArrangement

drna:AggregateSalesMilestonesReceivableExpense

drna:AlnylamCollaborationAndLicenseAgreement


Aggregate
Period End2020-12-31
Value6000000.0
Percentage of AggregateSalesMilestonesReceivableExpense100.0

drna:ChangeInFairValueOfDerivativeLiability

drna:ChangeInFairValueOfDerivativeLiability


Change
Period End2021-06-302021-03-31
Value250000.01500000.0
Percentage of ChangeInFairValueOfDerivativeLiability100.0100.0

drna:CollaborativeArrangementConsideration us-gaap:TypeOfArrangement

drna:CollaborativeArrangementConsideration

drna:NovoCollaborationAgreement


Collaborative
Period End2021-06-302021-03-312020-12-312020-09-30
Value-6.6236-3.8-3.5
Percentage of CollaborativeArrangementConsideration100.0100.0100.0100.0

drna:RocheCollaborationAgreement


Collaborative
Period End2021-06-302021-03-312020-12-312020-09-302019-10-302018-10-25
Value-14.2136-14.8-16.6206204
Percentage of CollaborativeArrangementConsideration215.257.7389.5474.30.00.0

drna:CollaborativeArrangementContingentSalesBasedMilestonePaymentReceivable us-gaap:SubsequentEventType, us-gaap:TypeOfArrangement

drna:CollaborativeArrangementContingentSalesBasedMilestonePaymentReceivable

us-gaap:SubsequentEvent, drna:Oxlumo


Collaborative
Period End2021-04-30
Value60
Percentage of CollaborativeArrangementContingentSalesBasedMilestonePaymentReceivable100.0

drna:CollaborativeArrangementDevelopmentCandidateNominationMilestoneAmountEarned us-gaap:TypeOfArrangement

drna:CollaborativeArrangementDevelopmentCandidateNominationMilestoneAmountEarned

drna:NovoCollaborationAgreement


Collaborative
Period End2020-12-31
Value2500000.0
Percentage of CollaborativeArrangementDevelopmentCandidateNominationMilestoneAmountEarned100.0

drna:NovoCollaborationAgreementAndNovoShareIssuanceAgreement


Collaborative
Period End2020-12-31
Value2500000.0
Percentage of CollaborativeArrangementDevelopmentCandidateNominationMilestoneAmountEarned100.0

drna:CollaborativeArrangementOptionExerciseFee us-gaap:TypeOfArrangement

drna:CollaborativeArrangementOptionExerciseFee

drna:BoehringerIngelheimAdditionalTargetAgreement


Collaborative
Period End2021-03-312020-12-312020-09-302017-10-27
Value5.00.00.05.0
Percentage of CollaborativeArrangementOptionExerciseFee100.00.00.0100.0

drna:CollaborativeArrangementProceedsFromSaleOfRoyaltyInterest us-gaap:SubsequentEventType, us-gaap:TypeOfArrangement

drna:CollaborativeArrangementProceedsFromSaleOfRoyaltyInterest

us-gaap:SubsequentEvent, drna:Oxlumo


Collaborative
Period End2021-04-30
Value180
Percentage of CollaborativeArrangementProceedsFromSaleOfRoyaltyInterest100.0

drna:CollaborativeArrangementRightsAndObligationsMaximumAggregateMilestonePayments

drna:CollaborativeArrangementRightsAndObligationsMaximumAggregateMilestonePayments


Collaborative
Period End2021-04-30
Value60
Percentage of CollaborativeArrangementRightsAndObligationsMaximumAggregateMilestonePayments100.0

drna:CollaborativeArrangementTargetsDeliveredMilestoneAmountEarned us-gaap:TypeOfArrangement

drna:CollaborativeArrangementTargetsDeliveredMilestoneAmountEarned

drna:NovoCollaborationAgreement


Collaborative
Period End2020-12-31
Value25
Percentage of CollaborativeArrangementTargetsDeliveredMilestoneAmountEarned100.0

drna:IncreaseDecreaseInDeferredChargesAndOtherOperatingAssets

drna:IncreaseDecreaseInDeferredChargesAndOtherOperatingAssets


Increase
Period End2020-12-31
Value-820000.0
Percentage of IncreaseDecreaseInDeferredChargesAndOtherOperatingAssets100.0

drna:IncreaseDecreaseInLeaseLiabilities

drna:IncreaseDecreaseInLeaseLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value-2.558-1.62416-1.568-6.6952.13110-0.496-1.4080.456
Percentage of IncreaseDecreaseInLeaseLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

drna:LesseeOperatingLeaseMonthlyBaseRentIncrease us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:LesseeOperatingLeaseMonthlyBaseRentIncrease

drna:SeventyFiveHaydenAvenue


Lessee
Period End2020-07-01
Value200000.0
Percentage of LesseeOperatingLeaseMonthlyBaseRentIncrease100.0

drna:OperatingLeasesIncreaseInRentExpensePerMonth

drna:OperatingLeasesIncreaseInRentExpensePerMonth


Operating
Period End2020-07-01
Value200000.0
Percentage of OperatingLeasesIncreaseInRentExpensePerMonth100.0

drna:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodFairValue us-gaap:AwardType

drna:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodFairValue

us-gaap:RestrictedStockUnitsRSU


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-31
Value1.9102.33.816
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodFairValue100.0100.0100.0100.0100.0

drna:SharePriceOne us-gaap:Range, us-gaap:AwardType

drna:SharePriceOne

srt:Maximum, us-gaap:EmployeeStockOption


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value30.7128.8826.6221.6122.5815.6115.4414.13015.7414.4112.785.723.993.47
Percentage of SharePriceOne100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0

srt:Minimum, us-gaap:EmployeeStockOption


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value25.7622.0717.8417.3315.6113.4612.1210.31012.749.149.303.242.91
Percentage of SharePriceOne83.976.467.080.269.186.278.573.00.080.963.472.80.081.283.9

us-gaap:AccretionAmortizationOfDiscountsAndPremiumsInvestments

us-gaap:AccretionAmortizationOfDiscountsAndPremiumsInvestments


Accretion
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-1182000.0-783000.0-537000.0-138000.0111000.0191000.0380000.0882000.01072000.01225000.0736000.0195000.0105000.090000.0
Percentage of AccretionAmortizationOfDiscountsAndPremiumsInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation

us-gaap:AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation


Adjustments
Period End2021-06-302021-03-312018-03-31
Value462000.01414000.035000.0
Percentage of AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation100.0100.0100.0

us-gaap:AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Adjustments
Period End2021-06-302021-03-312018-03-31
Value462000.01414000.035000.0
Percentage of AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation100.0100.0100.0

us-gaap:CapitalExpendituresIncurredButNotYetPaid

us-gaap:CapitalExpendituresIncurredButNotYetPaid


Capital
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-03-312016-03-31
Value84000.093000.01044000.0122000.0187000.0259000.0727000.0-527000.0-336000.0863000.01604000.038000.06000.0012000.044000.0
Percentage of CapitalExpendituresIncurredButNotYetPaid100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0

us-gaap:ContractWithCustomerLiabilityRevenueRecognized

us-gaap:ContractWithCustomerLiabilityRevenueRecognized


Contract
Period End2021-06-302021-03-312020-06-302020-03-312018-12-312018-09-302018-06-30
Value313038301.4661.51.5
Percentage of ContractWithCustomerLiabilityRevenueRecognized100.0100.0100.0100.0100.0100.0100.0

us-gaap:ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod

us-gaap:ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod


Contract
Period End2021-06-302021-03-312020-06-302020-03-31
Value6.431121.0110.588
Percentage of ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod100.0100.0100.0100.0

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings us-gaap:FairValueByLiabilityClass

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings

us-gaap:DerivativeFinancialInstrumentsLiabilities


Fair
Period End2021-06-302021-03-31
Value250000.01500000.0
Percentage of FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings100.0100.0

us-gaap:IncreaseDecreaseInContractWithCustomerLiability

us-gaap:IncreaseDecreaseInContractWithCustomerLiability


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-27.466-18.5016.229-43.688-38.831156217-4.761-5.6824.893178-1.545-1.545-1.545
Percentage of IncreaseDecreaseInContractWithCustomerLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities

us-gaap:IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-30
Value0.882.645-3.3662.5688.024-0.4880.6477.9742.601-1.7351.9291.472-0.1390.7120.177-0.312-0.192-0.084-0.4340.0731.185-1.366-1.591.1272.4110.3650.4880.654
Percentage of IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value0.3174.1640.080.4435.1866.802-2.4554.2442.953-0.886-0.22-0.6251.317-1.004-0.6220.950.2580.7550.1140.3530.314-0.367-0.282-0.1050.581-0.0170.579-0.3520.3090.6350.04-0.039-0.056-0.002
Percentage of IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInReceivables

us-gaap:IncreaseDecreaseInReceivables


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-28.12-3.446295.016-14.988-185.3541973.00.0-100.01000.00.00.0
Percentage of IncreaseDecreaseInReceivables100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.00.00.00.0

us-gaap:InvestmentIncomeInterest

us-gaap:InvestmentIncomeInterest


Investment
Period End2021-06-302021-03-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-30
Value111000.0280000.01729000.02613000.01503000.01880000.02136000.02018000.01082000.0401000.0330000.0288000.0179000.0179000.0143000.038000.053000.061000.066000.055000.046000.055000.034000.053000.027000.021000.08000.04000.03000.01000.0
Percentage of InvestmentIncomeInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InvestmentIncomeNet

us-gaap:InvestmentIncomeNet


Investment
Period End2020-09-302019-09-30
Value1050000.01880000.0
Percentage of InvestmentIncomeNet100.0100.0

us-gaap:OperatingLeaseExpense

us-gaap:OperatingLeaseExpense


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2896000.02654000.02562000.01893000.01837000.01803000.01360000.0471000.0471000.0445000.0
Percentage of OperatingLeaseExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherOperatingActivitiesCashFlowStatement

us-gaap:OtherOperatingActivitiesCashFlowStatement


Other
Period End2021-06-302021-03-312020-06-302020-03-312019-06-302019-03-31
Value32000.010000.057000.0-62000.000
Percentage of OtherOperatingActivitiesCashFlowStatement100.0100.0100.0100.00.00.0

us-gaap:PaymentsForProceedsFromOtherInvestingActivities

us-gaap:PaymentsForProceedsFromOtherInvestingActivities


Payments
Period End2020-12-312020-09-302020-06-302020-03-312019-06-302019-03-31
Value000-15000.000
Percentage of PaymentsForProceedsFromOtherInvestingActivities0.00.00.0100.00.00.0

us-gaap:PaymentsOfStockIssuanceCosts

us-gaap:PaymentsOfStockIssuanceCosts


Payments
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-04-112013-12-312013-09-30
Value800000.00104000.0000050000.0703000.0000-727000.0450000.0800000.01226000.075000.0
Percentage of PaymentsOfStockIssuanceCosts100.00.0100.00.00.00.00.0100.0100.00.00.00.0100.0100.0100.0100.0100.0

us-gaap:PaymentsRelatedToTaxWithholdingForShareBasedCompensation

us-gaap:PaymentsRelatedToTaxWithholdingForShareBasedCompensation


Payments
Period End2021-06-302021-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-31
Value462000.01414000.0000000035000.000011000.000027000.01000.00075000.0
Percentage of PaymentsRelatedToTaxWithholdingForShareBasedCompensation100.0100.00.00.00.00.00.00.00.0100.00.00.00.0100.00.00.00.0100.0100.00.00.0100.0

us-gaap:PaymentsToAcquireHeldToMaturitySecurities

us-gaap:PaymentsToAcquireHeldToMaturitySecurities


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302015-12-312015-09-302014-12-312014-09-30
Value2371532721001793494297172491441080.0292414150.0-0.0010.00.01640
Percentage of PaymentsToAcquireHeldToMaturitySecurities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.00.0100.00.0100.0100.0

us-gaap:ProceedsFromIssuanceOfCommonStock

us-gaap:ProceedsFromIssuanceOfCommonStock


Proceeds
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-112017-12-18
Value0.00.00.0390.00.00.00.00.011546
Percentage of ProceedsFromIssuanceOfCommonStock0.00.00.0100.00.00.00.00.00.0100.0100.0

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value127.582112.7965.9620.5886.2680.00.6460.1960.2780.9240.2410.6670.0750.1280.0010.0860.00.0680.00.4930.0240.1510.0280.2240.096
Percentage of ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.00.0100.0100.0100.0100.0100.0100.0

us-gaap:ProceedsFromPaymentsForOtherFinancingActivities

us-gaap:ProceedsFromPaymentsForOtherFinancingActivities


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-06-302019-03-31
Value-12000.0-10000.0-11000.0-10000.0-12000.0-12000.000
Percentage of ProceedsFromPaymentsForOtherFinancingActivities100.0100.0100.0100.0100.0100.00.00.0

us-gaap:ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities

us-gaap:ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value13421023516617084112781408831151520252010.0151515135.516415.07.57.5
Percentage of ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability

us-gaap:RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability


Right
Period End2020-09-302020-06-302020-03-31
Value0048000.0
Percentage of RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability0.00.0100.0

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability


Right
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value310.00.01.101250.00.00.667
Percentage of RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability100.00.00.0100.0100.00.00.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate us-gaap:Range, us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate

srt:Maximum, us-gaap:EmployeeStockOption


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value79.1678.9180.290.80450.795700.79560.8080.7931-0.1260.7790.78330.9090.0030.9080.808
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

srt:Minimum, us-gaap:EmployeeStockOption


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value77.7278.6880.150.78330.7914-0.00030.7940.79120.787900.770.7680.75900.7960.797
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate98.299.799.897.499.50.099.897.999.3-0.098.898.083.50.087.798.6

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate us-gaap:Range, us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate

srt:Maximum, us-gaap:EmployeeStockOption


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value1.150.930.370.00420.0171-0.00020.01840.02350.02620.0010.0290.02840.02640.00130.02040.0189
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

srt:Minimum, us-gaap:EmployeeStockOption


Share
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value0.90.51000.0070.00030.01370.01750.0224-0.00020.02780.02650.02320.00040.01870.0186
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate78.354.80.00.040.9-150.074.574.585.5-20.095.993.387.930.891.798.4

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value5.631-34.46.39.544-31.08.98.528-11.11.73.8
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan


Stock
Period End2021-06-302020-06-302019-06-302019-03-312018-12-312018-09-302018-03-31
Value125.8760.4890.3531.7520.9260.632
Percentage of StockIssuedDuringPeriodValueEmployeeStockPurchasePlan100.0100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stock
Period End2021-06-302020-06-302019-06-302019-03-312018-12-312018-09-302018-03-31
Value125.8760.4890.3531.7520.9260.632
Percentage of StockIssuedDuringPeriodValueEmployeeStockPurchasePlan100.0100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised


Stock
Period End2021-03-312020-09-302020-03-312019-06-302018-12-312018-06-30
Value7616000.02801000.0588000.0489000.0-1395000.0191000.0
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stock
Period End2021-03-312020-09-302020-03-312019-06-302018-12-312018-06-30
Value7616000.02801000.0588000.0489000.0-1395000.0191000.0
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised100.0100.0100.0100.0100.0100.0

drna:AccruedClinicalContractResearchAndManufacturingCostsCurrent

drna:AccruedClinicalContractResearchAndManufacturingCostsCurrent


Accrued
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-31
Value9.2971514108.5933.961.862.3132.82
Percentage of AccruedClinicalContractResearchAndManufacturingCostsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0

drna:AdditionalAreaOfRealEstateProperty us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:AdditionalAreaOfRealEstateProperty

drna:SeventyFiveHaydenAvenue


Additional
Period End2020-07-01
Value30446.0
Percentage of AdditionalAreaOfRealEstateProperty100.0

drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedGainCurrent us-gaap:FinancialInstrument

drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedGainCurrent

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value39000.0
Percentage of DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedGainCurrent100.0

drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossCurrent us-gaap:FinancialInstrument

drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossCurrent

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value13000.0
Percentage of DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossCurrent100.0

drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossNoncurrent us-gaap:FinancialInstrument

drna:DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossNoncurrent

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value34000.0
Percentage of DebtSecuritiesHeldToMaturityAccumulatedUnrecognizedLossNoncurrent100.0

drna:DeferredTaxAssetsLiabilitiesPropertyPlantAndEquipment

drna:DeferredTaxAssetsLiabilitiesPropertyPlantAndEquipment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-31
Value1346000.0408000.075000.042000.0-77000.0
Percentage of DeferredTaxAssetsLiabilitiesPropertyPlantAndEquipment100.0100.0100.0100.0100.0

drna:DeferredTaxAssetsOperatingLeaseLiability

drna:DeferredTaxAssetsOperatingLeaseLiability


Deferred
Period End2020-12-312019-12-312018-12-31
Value156.9050.0
Percentage of DeferredTaxAssetsOperatingLeaseLiability100.0100.00.0

drna:DeferredTaxLiabilitiesContractWithCustomerLiability

drna:DeferredTaxLiabilitiesContractWithCustomerLiability


Deferred
Period End2020-12-312019-12-31
Value1688000.0492000.0
Percentage of DeferredTaxLiabilitiesContractWithCustomerLiability100.0100.0

drna:LesseeOperatingLeaseLeaseNotYetCommencedLiability us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:LesseeOperatingLeaseLeaseNotYetCommencedLiability

drna:SeventyFiveHaydenAvenue


Lessee
Period End2021-06-30
Value21
Percentage of LesseeOperatingLeaseLeaseNotYetCommencedLiability100.0

drna:LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount us-gaap:Range, us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount

srt:Maximum, drna:SeventyFiveHaydenAvenue


Lessee
Period End2021-06-30
Value2600000.0
Percentage of LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount100.0

srt:Minimum, drna:SeventyFiveHaydenAvenue


Lessee
Period End2021-06-30
Value1900000.0
Percentage of LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount73.1

drna:OperatingAndFinanceLeaseLiabilityCurrent

drna:OperatingAndFinanceLeaseLiabilityCurrent


Operating
Period End2021-06-302021-03-312020-12-312019-12-31
Value3946000.04067000.03439000.03358000.0
Percentage of OperatingAndFinanceLeaseLiabilityCurrent100.0100.0100.0100.0

drna:OperatingAndFinanceLeaseLiabilityNoncurrent

drna:OperatingAndFinanceLeaseLiabilityNoncurrent


Operating
Period End2021-06-302021-03-312020-12-312019-12-31
Value61474820
Percentage of OperatingAndFinanceLeaseLiabilityNoncurrent100.0100.0100.0100.0

drna:OperatingLossCarryforwardsEstimatedLimitation

drna:OperatingLossCarryforwardsEstimatedLimitation


Operating
Period End2020-12-31
Value125
Percentage of OperatingLossCarryforwardsEstimatedLimitation100.0

drna:OtherPrepaidExpenseAndOtherAssetsCurrent

drna:OtherPrepaidExpenseAndOtherAssetsCurrent


Other
Period End2021-06-302020-12-312020-09-302020-06-302019-12-31
Value5656000.02590000.01729000.03457000.01145000.0
Percentage of OtherPrepaidExpenseAndOtherAssetsCurrent100.0100.0100.0100.0100.0

drna:PrepaidClinicalContractResearchAndManufacturingCostsCurrent

drna:PrepaidClinicalContractResearchAndManufacturingCostsCurrent


Prepaid
Period End2021-06-302020-12-312020-09-302020-06-302019-12-312018-12-312017-12-312016-12-312015-12-31
Value119.6518.7426.4064.2881.4191.9311.0280.649
Percentage of PrepaidClinicalContractResearchAndManufacturingCostsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccruedEmployeeBenefitsCurrent

us-gaap:AccruedEmployeeBenefitsCurrent


Accrued
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-312014-12-31
Value14108.0297.2984.0593.6841.9872.1132.0921.483
Percentage of AccruedEmployeeBenefitsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccruedLiabilitiesAndOtherLiabilities

us-gaap:AccruedLiabilitiesAndOtherLiabilities


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value2928283027192018108.1969.6498.1016.2996.4375.7265.135.4546.2625.7266.166.094.8986.3767.9917.3444.2553.8453.8122.8081.9471.286
Percentage of AccruedLiabilitiesAndOtherLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccruedProfessionalFeesCurrent

us-gaap:AccruedProfessionalFeesCurrent


Accrued
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302018-12-312017-12-312016-12-312015-12-31
Value2117000.01506000.01071000.01519000.05004000.01693000.01488000.0867000.0965000.0
Percentage of AccruedProfessionalFeesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AreaOfRealEstateProperty

us-gaap:AreaOfRealEstateProperty


Area
Period End2020-07-01
Value91728.0
Percentage of AreaOfRealEstateProperty100.0

us-gaap:AreaOfRealEstateProperty us-gaap:RealEstateAndAccumulatedDepreciationDescriptionOfProperty

drna:SeventyFiveHaydenAvenue


Area
Period End2020-07-012020-01-14
Value91728.061282.0
Percentage of AreaOfRealEstateProperty100.00.0

us-gaap:AssetsFairValueDisclosure

us-gaap:AssetsFairValueDisclosure


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value7145505756166767153533173503752931647878977277263853686885100115849451
Percentage of AssetsFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AssetsFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel1


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value22616413221020325015651104160442938235126261512272714454317172046
Percentage of AssetsFairValueDisclosure31.729.923.034.130.135.144.416.230.042.815.317.948.529.353.036.333.858.833.051.640.321.253.543.915.521.321.689.1

us-gaap:FairValueInputsLevel2


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value4883854424064724641962652452142491344055454651112626415439569766735.111
Percentage of AssetsFairValueDisclosure68.370.177.065.969.964.955.683.870.057.284.782.151.570.747.063.766.241.267.048.459.778.846.556.184.578.778.49.9

us-gaap:CashAndCashEquivalentsFairValueDisclosure us-gaap:CashAndCashEquivalents

us-gaap:CashAndCashEquivalentsFairValueDisclosure

us-gaap:MoneyMarketFunds


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value220159126204197245152471011604429382351262615122727144543171720
Percentage of CashAndCashEquivalentsFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:CashAndCashEquivalentsFairValueDisclosure us-gaap:CashAndCashEquivalents, us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:MoneyMarketFunds, us-gaap:FairValueInputsLevel1


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value220159126204197245152471011604429382351262615122727144543171720
Percentage of CashAndCashEquivalentsFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ContractWithCustomerLiability

us-gaap:ContractWithCustomerLiability


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-312016-12-31
Value4284564744685125513941771821881839.270.0
Percentage of ContractWithCustomerLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

us-gaap:ContractWithCustomerLiability us-gaap:TypeOfArrangement

drna:AlexionCollaborativeResearchAndLicenseAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value101216215852
Percentage of ContractWithCustomerLiability2.42.73.54.611.413.4

drna:AlexionCollaborativeResearchAndLicenseAgreementAmendment


Contract
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value2929292520
Percentage of ContractWithCustomerLiability6.86.46.35.55.1

drna:AlexionCollaborativeResearchAndLicenseAgreementAndAmendment


Contract
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value3941464752
Percentage of ContractWithCustomerLiability9.19.19.810.113.4

drna:AlexionCollaborativeResearchAndLicenseAndShareIssuanceAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-30
Value39414652
Percentage of ContractWithCustomerLiability9.19.19.811.2

drna:BoehringerIngelheimAdditionalTargetAgreement


Contract
Period End2020-09-30
Value0.3
Percentage of ContractWithCustomerLiability0.1

drna:BoehringerIngelheimAgreement


Contract
Period End2020-09-302020-06-302019-12-31
Value0.1061.02.273
Percentage of ContractWithCustomerLiability0.00.20.6

drna:LillyCollaborationAndLicenseAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-03-312018-12-31
Value9398104104116125135148148
Percentage of ContractWithCustomerLiability21.721.522.122.322.822.834.378.781.2

drna:NovoCollaborationAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value1791861921711751774.2
Percentage of ContractWithCustomerLiability41.940.840.636.634.232.21.1

drna:RocheCollaborationAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value117130130144161180200
Percentage of ContractWithCustomerLiability27.328.627.530.931.532.850.6

us-gaap:ContractWithCustomerLiabilityNoncurrent

us-gaap:ContractWithCustomerLiabilityNoncurrent


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value268318336268290327182811041281143.09
Percentage of ContractWithCustomerLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ContractWithCustomerLiabilityNoncurrent us-gaap:TypeOfArrangement

drna:AlexionCollaborativeResearchAndLicenseAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value3.1664.497.5283.753176553
Percentage of ContractWithCustomerLiabilityNoncurrent1.21.42.21.45.919.929.0

drna:AlexionCollaborativeResearchAndLicenseAgreementAmendment


Contract
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value2729201818
Percentage of ContractWithCustomerLiabilityNoncurrent10.39.26.06.710.3

drna:AlexionCollaborativeResearchAndLicenseAgreementAndAmendment


Contract
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value3033272125
Percentage of ContractWithCustomerLiabilityNoncurrent11.510.68.38.113.8

drna:LillyCollaborationAndLicenseAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-312019-09-302019-06-30
Value395364535672140145
Percentage of ContractWithCustomerLiabilityNoncurrent14.916.919.219.919.539.6171.0139.6

drna:NovoCollaborationAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value1421561621311353.359
Percentage of ContractWithCustomerLiabilityNoncurrent53.249.248.449.146.51.8

drna:RocheCollaborationAgreement


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value557481618181
Percentage of ContractWithCustomerLiabilityNoncurrent20.523.324.222.828.144.8

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLoss us-gaap:FinancialInstrument

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLoss

us-gaap:USTreasurySecurities


Debt
Period End2021-06-302020-12-31
Value488442
Percentage of DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLoss100.0100.0

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossCurrent

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossCurrent


Debt
Period End2021-06-302020-12-31
Value371442
Percentage of DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossCurrent100.0100.0

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossCurrent us-gaap:FinancialInstrument

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value371
Percentage of DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossCurrent100.0

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossNoncurrent

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossNoncurrent


Debt
Period End2021-06-30
Value116
Percentage of DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossNoncurrent100.0

us-gaap:DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossNoncurrent us-gaap:FinancialInstrument

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value116
Percentage of DebtSecuritiesHeldToMaturityExcludingAccruedInterestAfterAllowanceForCreditLossNoncurrent100.0

us-gaap:DebtSecuritiesHeldToMaturityFairValueCurrent us-gaap:FinancialInstrument

us-gaap:DebtSecuritiesHeldToMaturityFairValueCurrent

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value371
Percentage of DebtSecuritiesHeldToMaturityFairValueCurrent100.0

us-gaap:DebtSecuritiesHeldToMaturityFairValueNoncurrent us-gaap:FinancialInstrument

us-gaap:DebtSecuritiesHeldToMaturityFairValueNoncurrent

us-gaap:USTreasurySecurities


Debt
Period End2021-06-30
Value116
Percentage of DebtSecuritiesHeldToMaturityFairValueNoncurrent100.0

us-gaap:DeferredIncome

us-gaap:DeferredIncome


Deferred
Period End2021-04-30
Value180
Percentage of DeferredIncome100.0

us-gaap:DeferredIncomeCurrent

us-gaap:DeferredIncomeCurrent


Deferred
Period End2021-06-30
Value1098000.0
Percentage of DeferredIncomeCurrent100.0

us-gaap:DeferredIncomeNoncurrent

us-gaap:DeferredIncomeNoncurrent


Deferred
Period End2021-06-30
Value178
Percentage of DeferredIncomeNoncurrent100.0

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredIncomeTaxLiabilities


Deferred
Period End2020-12-312019-12-312018-12-31
Value199.2640.0
Percentage of DeferredIncomeTaxLiabilities100.0100.00.0

us-gaap:DeferredTaxAssetsDerivativeInstruments

us-gaap:DeferredTaxAssetsDerivativeInstruments


Deferred
Period End2020-12-31
Value1724000.0
Percentage of DeferredTaxAssetsDerivativeInstruments100.0

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsGross


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value14885364247484930
Percentage of DeferredTaxAssetsGross100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value318000.0415000.0516000.0618000.01044000.02431000.02646000.01465000.0
Percentage of DeferredTaxAssetsInProcessResearchAndDevelopment100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value8458243236374127
Percentage of DeferredTaxAssetsOperatingLossCarryforwards100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value307.3863.9883.4812.9823.512.361.806
Percentage of DeferredTaxAssetsTaxCreditCarryforwardsResearch100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits

us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value14117.6446.0667.2985.3692.479
Percentage of DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets


Deferred
Period End2020-12-312019-12-312018-12-31
Value2679000.01939000.00
Percentage of DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets100.0100.00.0

us-gaap:DeferredTaxLiabilitiesLeasingArrangements

us-gaap:DeferredTaxLiabilitiesLeasingArrangements


Deferred
Period End2020-12-312019-12-31
Value146.833
Percentage of DeferredTaxLiabilitiesLeasingArrangements100.0100.0

us-gaap:DerivativeLiabilities

us-gaap:DerivativeLiabilities


Derivative
Period End2021-06-302021-03-312020-12-31
Value7750000.07500000.06000000.0
Percentage of DerivativeLiabilities100.0100.0100.0

us-gaap:DerivativeLiabilities us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel3


Derivative
Period End2021-06-302021-03-312020-12-31
Value7750000.07500000.06000000.0
Percentage of DerivativeLiabilities100.0100.0100.0

us-gaap:DerivativeLiabilitiesNoncurrent

us-gaap:DerivativeLiabilitiesNoncurrent


Derivative
Period End2021-06-302021-03-312020-12-31
Value7750000.07500000.06000000.0
Percentage of DerivativeLiabilitiesNoncurrent100.0100.0100.0

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions us-gaap:AwardType

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions

us-gaap:RestrictedStockUnitsRSU


Employee
Period End2020-12-31
Value17
Percentage of EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions100.0

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions


Employee
Period End2020-12-31
Value76
Percentage of EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions100.0

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue us-gaap:FairValueByLiabilityClass

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue

us-gaap:DerivativeFinancialInstrumentsLiabilities


Fair
Period End2021-06-302021-03-312020-12-31
Value7750000.07500000.06000000.0
Percentage of FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue100.0100.0100.0

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiability


Finance
Period End2020-12-31
Value205000.0
Percentage of FinanceLeaseLiability100.0

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDue


Finance
Period End2020-12-31
Value242000.0
Percentage of FinanceLeaseLiabilityPaymentsDue100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths


Finance
Period End2020-12-31
Value64000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFive


Finance
Period End2020-12-31
Value2000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearFive100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFour


Finance
Period End2020-12-31
Value56000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearFour100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearThree


Finance
Period End2020-12-31
Value60000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearThree100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearTwo


Finance
Period End2020-12-31
Value60000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearTwo100.0

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount


Finance
Period End2020-12-31
Value37000.0
Percentage of FinanceLeaseLiabilityUndiscountedExcessAmount100.0

us-gaap:FinanceLeaseRightOfUseAsset

us-gaap:FinanceLeaseRightOfUseAsset


Finance
Period End2020-12-31
Value187000.0
Percentage of FinanceLeaseRightOfUseAsset100.0

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent


Finance
Period End2020-12-31
Value9.0
Percentage of FinanceLeaseWeightedAverageDiscountRatePercent100.0

us-gaap:FinancialLiabilitiesFairValueDisclosure

us-gaap:FinancialLiabilitiesFairValueDisclosure


Financial
Period End2021-06-302021-03-312020-12-31
Value7750000.07500000.06000000.0
Percentage of FinancialLiabilitiesFairValueDisclosure100.0100.0100.0

us-gaap:FinancialLiabilitiesFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel3


Financial
Period End2021-06-302021-03-312020-12-31
Value7750000.07500000.06000000.0
Percentage of FinancialLiabilitiesFairValueDisclosure100.0100.0100.0

us-gaap:HeldToMaturitySecurities us-gaap:FinancialInstrument

us-gaap:HeldToMaturitySecurities

us-gaap:USTreasurySecurities


Held
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value3854424054714611962652442112481333944
Percentage of HeldToMaturitySecurities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain us-gaap:FinancialInstrument

us-gaap:HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain

us-gaap:USTreasurySecurities


Held
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value39000.070000.0163000.0637000.01453000.03094000.0160000.0202000.0245000.024000.00000
Percentage of HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.00.00.0

us-gaap:HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss us-gaap:FinancialInstrument

us-gaap:HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss

us-gaap:USTreasurySecurities


Held
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value47000.05000.012000.02000.01000.006000.03000.004000.043000.057000.017000.030000.0
Percentage of HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss100.0100.0100.0100.0100.00.0100.0100.00.0100.0100.0100.0100.0100.0

us-gaap:HeldToMaturitySecuritiesCurrent

us-gaap:HeldToMaturitySecuritiesCurrent


Held
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value385442405471461196265244211248133395444444910252540533841696570
Percentage of HeldToMaturitySecuritiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:HeldToMaturitySecuritiesFairValue us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:FinancialInstrument

us-gaap:HeldToMaturitySecuritiesFairValue

us-gaap:FairValueInputsLevel2, us-gaap:USTreasurySecurities


Held
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value4883854424064724641962652452112481333944
Percentage of HeldToMaturitySecuritiesFairValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:HeldToMaturitySecuritiesFairValue us-gaap:FinancialInstrument

us-gaap:USTreasurySecurities


Held
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value4883854424064724641962652452112481333944
Percentage of HeldToMaturitySecuritiesFairValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:HostingArrangementServiceContractImplementationCostCapitalizedAfterAccumulatedAmortization

us-gaap:HostingArrangementServiceContractImplementationCostCapitalizedAfterAccumulatedAmortization


Hosting
Period End2020-12-31
Value2700000.0
Percentage of HostingArrangementServiceContractImplementationCostCapitalizedAfterAccumulatedAmortization100.0

us-gaap:InterestReceivable

us-gaap:InterestReceivable


Interest
Period End2021-06-302020-12-312020-09-302020-06-302019-12-31
Value1868000.01345000.0953000.01327000.0918000.0
Percentage of InterestReceivable100.0100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive


Lessee
Period End2020-12-31
Value28
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive


Lessee
Period End2020-12-31
Value9267000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour


Lessee
Period End2020-12-31
Value8997000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree


Lessee
Period End2020-12-31
Value8735000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo


Lessee
Period End2020-12-31
Value8480000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths


Lessee
Period End2020-12-31
Value7351000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths100.0

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent


Operating
Period End2020-12-31
Value8.0
Percentage of OperatingLeaseWeightedAverageDiscountRatePercent100.0

us-gaap:OperatingLossCarryforwards us-gaap:IncomeTaxAuthority

us-gaap:OperatingLossCarryforwards

us-gaap:DomesticCountry


Operating
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value279202158113899257
Percentage of OperatingLossCarryforwards100.0100.0100.0100.0100.0100.0100.0

us-gaap:StateAndLocalJurisdiction


Operating
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value324196148102777753
Percentage of OperatingLossCarryforwards115.996.993.490.086.883.992.3

us-gaap:PrepaidInsurance

us-gaap:PrepaidInsurance


Prepaid
Period End2021-06-302020-12-312020-09-302020-06-302019-12-312018-12-312017-12-312016-12-312015-12-31
Value1749000.0817000.01286000.01351000.0583000.0341000.0318000.0352000.0390000.0
Percentage of PrepaidInsurance100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization


Property
Period End2020-12-312019-12-31
Value5432000.06560000.0
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization


Property
Period End2021-06-302021-03-312020-12-312019-12-31
Value2318177.076
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization100.0100.0100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization


Property
Period End2020-12-312019-12-31
Value2213
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization us-gaap:PropertyPlantAndEquipmentByType

drna:LabEquipment


Property
Period End2020-12-312019-12-31
Value8.6379.147
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization37.667.1

drna:OfficeAndComputerEquipment


Property
Period End2020-12-312019-12-31
Value2.0492.425
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization8.917.8

us-gaap:ConstructionInProgress


Property
Period End2020-12-312019-12-31
Value100.238
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization43.71.7

us-gaap:FurnitureAndFixtures


Property
Period End2020-12-312019-12-31
Value1.2511.569
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization5.411.5

us-gaap:LeaseholdImprovements


Property
Period End2020-12-312019-12-31
Value1.0030.257
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization4.41.9

us-gaap:RestrictedCashAndCashEquivalents

us-gaap:RestrictedCashAndCashEquivalents


Restricted
Period End2021-06-302021-03-312020-06-302020-03-312014-03-312013-12-31
Value5618000.05618000.05563000.05563000.0264000.0264000.0
Percentage of RestrictedCashAndCashEquivalents100.0100.0100.0100.0100.0100.0

us-gaap:RestrictedCashAndCashEquivalentsAtCarryingValue

us-gaap:RestrictedCashAndCashEquivalentsAtCarryingValue


Restricted
Period End2020-12-31
Value744000.0
Percentage of RestrictedCashAndCashEquivalentsAtCarryingValue100.0

us-gaap:RestrictedCashAndCashEquivalentsNoncurrent

us-gaap:RestrictedCashAndCashEquivalentsNoncurrent


Restricted
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312015-12-31
Value5618000.05618000.05618000.06362000.05563000.05563000.03894000.03544000.03544000.03544000.0744000.0744000.0744000.0744000.0744000.01116000.01116000.01116000.01116000.01116000.0
Percentage of RestrictedCashAndCashEquivalentsNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RestrictedCashEquivalents us-gaap:LeaseContractualTerm

us-gaap:RestrictedCashEquivalents

drna:HaydenAvenueLetterOfCredit


Restricted
Period End2020-07-01
Value800000.0
Percentage of RestrictedCashEquivalents100.0

us-gaap:RestrictedInvestmentsAtFairValue us-gaap:CashAndCashEquivalents

us-gaap:RestrictedInvestmentsAtFairValue

us-gaap:MoneyMarketFunds


Restricted
Period End2021-06-302021-03-312020-12-312020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-31
Value5618000.05618000.06362000.05563000.03894000.03544000.03544000.03544000.0744000.0744000.0744000.0744000.0744000.01116000.01116000.01116000.01116000.01116000.01116000.01116000.01116000.01116000.01116000.01116000.0
Percentage of RestrictedInvestmentsAtFairValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RestrictedInvestmentsAtFairValue us-gaap:CashAndCashEquivalents, us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:MoneyMarketFunds, us-gaap:FairValueInputsLevel1


Restricted
Period End2021-06-302021-03-312020-12-312020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value5618000.05618000.06362000.05563000.03894000.03544000.03544000.0000
Percentage of RestrictedInvestmentsAtFairValue100.0100.0100.0100.0100.0100.0100.00.00.00.0

us-gaap:RestrictedInvestmentsAtFairValue us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:RestrictedCashAndCashEquivalentsCashAndCashEquivalents

us-gaap:FairValueInputsLevel1, us-gaap:MoneyMarketFunds


Restricted
Period End2020-09-302020-06-302019-12-31
Value6362000.05563000.03894000.0
Percentage of RestrictedInvestmentsAtFairValue0.00.0100.0

us-gaap:RestrictedInvestmentsAtFairValue us-gaap:RestrictedCashAndCashEquivalentsCashAndCashEquivalents

us-gaap:MoneyMarketFunds


Restricted
Period End2020-09-302020-06-302019-12-31
Value6362000.05563000.03894000.0
Percentage of RestrictedInvestmentsAtFairValue0.00.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue

us-gaap:RestrictedStockUnitsRSU


Share
Period End2020-12-312019-12-31
Value21.70
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue100.00.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice


Share
Period End2020-12-31
Value12.13
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue


Share
Period End2020-12-312019-03-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Value108289.40.10.20.43.2410.00.007
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue100.0100.0100.0100.0100.0100.0100.00.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue


Share
Period End2020-12-31
Value106
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice


Share
Period End2020-12-31
Value14.49
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice100.0

us-gaap:SharePrice us-gaap:Range, us-gaap:AwardType

us-gaap:SharePrice

srt:Maximum, us-gaap:EmployeeStockOption


Share
Period End2020-12-312019-12-312018-12-312017-12-31
Value26.6226.4815.749.71
Percentage of SharePrice100.0100.0100.0100.0

srt:Minimum, us-gaap:EmployeeStockOption


Share
Period End2020-12-312019-12-312018-12-312017-12-31
Value15.6110.319.142.94
Percentage of SharePrice58.638.958.130.3

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1


Sharebased
Period End2020-12-31
Value72
Percentage of SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1100.0

us-gaap:TaxCreditCarryforwardAmount us-gaap:IncomeTaxAuthority

us-gaap:TaxCreditCarryforwardAmount

stpr:MA


Tax
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-31
Value6.13.31.41.31.61.4
Percentage of TaxCreditCarryforwardAmount100.0100.0100.0100.0100.0100.0

us-gaap:DomesticCountry


Tax
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-31
Value297.12.62.12.42.1
Percentage of TaxCreditCarryforwardAmount490.2215.2185.7161.5150.0150.0

us-gaap:UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate

us-gaap:UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate


Unrecognized
Period End2020-12-312019-12-31
Value5500000.03000000.0
Percentage of UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate100.0100.0

Line plots across dimensions of each concept


us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities
(None,)
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amountus-gaap: Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities
TTM Greenblatt ROC
_
(None,)
T T M  Greenblatt  R O C_
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:TypeOfArrangement
(None,)
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Type Of Arrangement
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components
us-gaap:PropertyPlantAndEquipmentGross
us-gaap:PropertyPlantAndEquipmentByType
(None,)
Property Plant And Equipment Grossus-gaap: Property Plant And Equipment By Type
us-gaap:ContractWithCustomerLiabilityCurrent
us-gaap:TypeOfArrangement
(None,)
Contract With Customer Liability Currentus-gaap: Type Of Arrangement
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components
us-gaap:ShareBasedCompensation
us-gaap:IncomeStatementLocation
(None,)
Share Based Compensationus-gaap: Income Statement Location