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Earnings Per Share Basic 0.56-9.53-3.620.203.852.675.559.0912.068.276.933.05-0.70-0.59-0.31-0.35NANANANANANANANANANANANA
Earnings Per Share Diluted 0.56-9.53-3.620.193.662.535.248.5811.297.706.462.84-0.70-0.59-0.31-0.35NANANANANANANANANANANANA

    2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31
Revenue From Contract With Customer Excluding Assessed Tax 2811.001831.00344.001862.005084.003364.004749.006066.007211.004969.004354.001937.00570.75157.9166.358.3914.0517.0513.0816.0235.4241.7628.8529.0491.9042.4741.1230.33
Revenues 2811.001831.00344.001862.005084.003364.004749.006066.007211.004969.004354.001937.00570.75157.9166.358.3914.0517.0513.0816.0235.4241.7628.8529.0491.9042.4741.1230.33
Cost Of Goods And Services Sold 929.002241.00731.00792.001918.001100.001381.001017.00952.00722.00750.00193.00NANANANANANANANANANANANANANANANA
Costs And Expenses 2805.003843.002211.002228.003504.002198.002302.001839.001801.001411.001292.00671.00846.54392.00189.00139.00NANANANANANANANANANANANA
Research And Development Expense 1406.001160.001148.001131.001211.00820.00710.00554.00648.00521.00421.00401.00758.86344.49151.86115.14117.52119.72128.50130.57150.43109.05104.4890.12NANANANA
General And Administrative Expense 470.00442.00332.00305.00375.00278.00211.00268.00201.00168.00121.0077.0078.9948.5436.6224.1125.6328.1928.5227.2838.0218.5221.3916.32NANANANA
Operating Income Loss 6.00-2012.00-1867.00-366.001580.001166.002447.004227.005410.003558.003062.001266.00-275.04-235.12-122.13-130.86-130.56-130.86-143.94-141.83-153.03-85.82-97.02-77.40-41.83-67.87-94.19-65.46
Allocated Share Based Compensation Expense 79.0077.0074.0075.0062.0070.0050.0044.0037.0040.0035.0030.0025.4823.2123.9220.4120.3320.8021.5018.5031.6414.7214.3511.85NANANANA
Income Tax Expense Benefit -147.001672.00-369.00-384.00190.00174.00277.00572.00542.00219.00283.0039.001.470.860.150.07-0.17-0.18-0.32-0.020.170.000.160.00NANANANA
Net Income Loss 217.00-3630.00-1380.0079.001465.001043.002197.003657.004868.003333.002780.001221.00-272.49-233.64-116.71-124.23-123.12-123.19-135.05-132.66-141.43-80.33-90.60-72.38NANANANA
Comprehensive Income Net Of Tax 305.00-3578.00-1376.00182.001446.00932.002141.003497.004813.003348.002795.001219.00-274.26-237.11-102.33-132.16-124.14-123.11-132.90-130.75-141.82-79.24-89.46-74.37NANANANA

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Assets 18426.0019450.0021884.0024125.0025858.0026056.0026043.0027609.0024669.0020923.0016153.0012694.007336.754650.873486.012067.541589.421590.901685.281806.211962.15NANANA1084.49NANANA
Liabilities 4572.005995.004935.005262.006735.008064.008058.0010534.0010524.0010799.009449.008856.004775.381891.08539.12426.67414.61339.09346.73360.17431.91NANANA459.19NANANA
Liabilities And Stockholders Equity 18426.0019450.0021884.0024125.0025858.0026056.0026043.0027609.0024669.0020923.0016153.0012694.007336.754650.873486.012067.541589.421590.901685.281806.211962.15NANANA1084.49NANANA
Stockholders Equity 13854.0013455.0016949.0018863.0019123.0017992.0017985.0017075.0014145.0010124.006704.003838.002561.382759.802946.891640.871174.811251.811338.551446.031530.24-757.13-688.77-613.71-551.37NANANA

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Assets Current 10325.0010799.0010599.0012122.0013431.0014297.0013563.0016350.0016071.0013425.0010969.0011703.006297.883577.212796.741249.941128.801094.471097.421140.831563.01NANANA783.22NANANA
Cash And Cash Equivalents At Carrying Value 2907.002932.003801.003441.003205.003027.002873.005048.006848.005550.005603.005442.002623.851505.581761.63391.72235.88173.71151.62502.93658.36167.06140.6290.48134.86NANANA
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents 2928.002953.003822.003461.003217.003041.002885.005060.006860.005561.005614.005453.002635.931517.671773.45403.54247.70185.53163.45514.76670.49179.42152.98102.51147.61NANANA
Accounts Receivable Net Current 892.001866.00232.001113.001385.002695.002691.003173.003175.003142.002020.003210.001390.56190.5033.365.625.032.803.505.6511.69NANANA11.88NANANA
Inventory Net 202.00487.00715.00732.00949.002077.001921.001942.001441.00965.00643.00494.0046.53NANANANANANANANANANANANANANANA
Other Assets Current 88.0096.0053.0064.0065.0085.0076.0036.0055.0043.0038.00NA21.00NANANANANANANANANANANANANANANA
Prepaid Expense And Other Assets Current 627.00873.001193.001354.001195.001177.001054.001120.00728.00412.00316.00264.00252.15109.3845.3423.9019.4026.6822.4925.2928.40NANANA12.83NANANA

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Finite Lived Intangible Assets Net 44.0045.0046.0048.00NANANANANANANANANANANANANANANANANANANANANANANANA
Other Assets Noncurrent 685.00661.001290.001164.00988.0038.0075.0082.0034.004.002.001.001.882.051.571.741.932.092.562.442.64NANANA4.59NANANA
Available For Sale Debt Securities Amortized Cost Basis 10519.0010182.0011098.0013265.0015479.0014525.0015564.0014509.0010774.009806.006599.002759.002618.342456.721300.861333.431024.111160.681279.871042.521037.37NANA1037.37768.18NANANA

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Liabilities Current 3015.004385.003123.003499.004923.006807.006812.009238.009128.009957.008840.008441.004388.811473.56161.65134.58143.12147.84161.99159.16222.80NANANA191.46NANANA
Accounts Payable Current 520.00494.00310.00389.00487.00330.00181.00199.00302.0087.0077.008.0018.3620.5218.8211.037.0911.7429.6138.5131.21NANANA20.73NANANA
Taxes Payable Current 63.0056.0047.0066.0048.0066.00349.001592.00876.00565.00377.00NANANANANANANANANANANANANANANANANA
Accrued Liabilities Current 1798.002224.001490.001613.002101.001856.001780.001608.001472.001076.00848.00753.00469.59208.8389.2055.0267.6560.0844.5942.1879.07NANANA72.72NANANA
Other Liabilities Current 66.00239.00236.00212.00249.00553.00409.00240.00225.00252.00613.00149.0033.669.708.389.695.065.834.394.513.46NANANA1.28NANANA
Contract With Customer Liability Current 568.001372.001040.001219.002038.004002.004093.005599.006253.007977.007302.007531.003867.191234.5145.2458.8463.3170.1983.4073.96109.06NANANANANANANA

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Other Liabilities Noncurrent 256.00172.00173.00163.00135.0081.00113.0091.0076.001.001.002.001.852.181.221.250.140.160.190.210.26NANANA1.53NANANA
Operating Lease Liability Noncurrent 643.00697.00104.0096.0092.0079.0087.0095.00106.00105.00105.0096.0097.4298.9599.64108.9293.67NANANANANANANANANANANA

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Stockholders Equity 13854.0013455.0016949.0018863.0019123.0017992.0017985.0017075.0014145.0010124.006704.003838.002561.382759.802946.891640.871174.811251.811338.551446.031530.24-757.13-688.77-613.71-551.37NANANA
Additional Paid In Capital 371.00277.00193.00731.001173.001488.002413.003644.004211.005003.004931.004860.004801.854726.014675.993267.652669.432618.492582.132556.712538.16NANANA71.68NANANA
Retained Earnings Accumulated Deficit 13606.0013389.0017019.0018399.0018320.0016855.0015812.0013615.009958.005090.001757.00-1023.00-2243.52-1971.03-1737.40-1620.68-1500.00-1369.55-1246.35-1111.30-1006.63NANANA-621.89NANANA
Accumulated Other Comprehensive Income Loss Net Of Tax -123.00-211.00-263.00-267.00-370.00-351.00-240.00-184.00-24.0031.0016.001.003.004.788.26-6.131.802.832.740.59-1.32NANANA-1.16NANANA
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value 79.0077.0074.0075.0062.0070.0050.0044.0037.0040.0035.0030.0025.4823.2123.9220.4120.3320.8021.5018.5031.6414.7214.3511.85NANANANA

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Net Cash Provided By Used In Operating Activities 622.00-1600.00-915.00-1225.001662.00252.00304.002763.003310.003276.004063.002971.001264.29892.75-23.88-106.19-95.77-107.05-112.22-143.93-91.02-80.21-48.25-111.39NANANANA
Net Cash Provided By Used In Investing Activities -538.00789.001944.002011.00-1048.00945.00-1152.00-3921.00-1138.00-3327.00-3878.00-180.00-190.13-1178.2612.48-316.02130.35113.37-246.90-11.766.79116.08-11.64-483.70NANANANA
Net Cash Provided By Used In Financing Activities -109.00-58.00-668.00-542.00-438.00-1041.00-1327.00-642.00NANA-24.0026.0044.1129.731381.31578.0527.5915.777.81-0.05575.91-9.43110.36550.00NANANANA

    2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31
Net Cash Provided By Used In Operating Activities 622.00-1600.00-915.00-1225.001662.00252.00304.002763.003310.003276.004063.002971.001264.29892.75-23.88-106.19-95.77-107.05-112.22-143.93-91.02-80.21-48.25-111.39NANANANA
Net Income Loss 217.00-3630.00-1380.0079.001465.001043.002197.003657.004868.003333.002780.001221.00-272.49-233.64-116.71-124.23-123.12-123.19-135.05-132.66-141.43-80.33-90.60-72.38NANANANA
Depreciation Depletion And Amortization 203.00246.0090.0078.0080.00113.0076.0079.0078.0070.0069.0015.007.718.507.607.458.907.307.507.307.396.505.905.15NANANANA
Increase Decrease In Accounts Receivable -974.001634.00-881.00-272.00-1310.004.00-483.00-1.0033.001122.00-1190.001819.001200.06157.1427.410.582.23-0.70-2.15-6.041.84-1.553.39-3.88NANANANA
Increase Decrease In Inventories -285.00-228.00-18.00-216.00-1128.00156.00-21.00501.00476.00322.00148.00448.00NANANANANANANANANANANANANANANANA
Increase Decrease In Accounts Payable 21.00179.00-70.00-117.00151.00145.00-21.00-35.00178.00-18.0059.00-15.00-1.762.169.142.33-4.78-17.71-3.201.7314.302.06-2.811.47NANANANA
Share Based Compensation 79.0077.0074.0075.0062.0070.0050.0044.0037.0040.0035.0030.0025.4823.2123.9220.4120.3320.8021.5018.5031.6414.7214.3511.85NANANANA

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Net Cash Provided By Used In Investing Activities -538.00789.001944.002011.00-1048.00945.00-1152.00-3921.00-1138.00-3327.00-3878.00-180.00-190.13-1178.2612.48-316.02130.35113.37-246.90-11.766.79116.08-11.64-483.70NANANANA
Payments To Acquire Property Plant And Equipment 220.00140.00234.00113.0092.0089.0087.00132.00120.0099.0030.0035.0023.3019.2918.636.226.666.7110.597.5913.6426.1434.0831.91NANANANA

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Net Cash Provided By Used In Financing Activities -109.00-58.00-668.00-542.00-438.00-1041.00-1327.00-642.00NANA-24.0026.0044.1129.731381.31578.0527.5915.777.81-0.05575.91-9.43110.36550.00NANANANA
Payments For Repurchase Of Common Stock 0.00-1.00628.00526.00402.001006.001298.00623.00NANANANANANANANANANANANANANANANANANANANA

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Revenues 2811.001831.00344.001862.005084.003364.004749.006066.007211.004969.004354.001937.00570.75157.9166.358.3914.0517.0513.0816.0235.4241.7628.8529.0491.9042.4741.1230.33
Other Collaborative Parties, Collaboration Arrangement Including Arrangements With Affiliate 0.000.001.00NA1.000.001.001.00-1.004.001.001.00NANANANANANANANANANANANANANANANA
Other Grant Revenue, Grant -2.000.004.004.005.003.004.004.003.0012.005.002.002.852.380.861.000.392.571.18NANANANANANANANANA
Revenue From Contract With Customer Excluding Assessed Tax 2811.001831.00344.001862.005084.003364.004749.006066.007211.004969.004354.001937.00570.75157.9166.358.3914.0517.0513.0816.0235.4241.7628.8529.0491.9042.4741.1230.33
Other Collaborative Parties, Collaboration Arrangement Including Arrangements With Affiliate 0.00NANANA1.000.001.001.00-1.004.001.001.00NANANANANANANANANANANANANANANANA
Vertex, Collaboration Arrangement Including Arrangements With Affiliate 20.0030.0022.0010.0015.004.0025.004.003.005.009.009.005.815.452.002.001.890.50NANANANANANANANANANA
Biomedical Advanced Research And Development Authority, Grant 0.0044.0024.0020.00-70.00141.00179.00122.00259.00128.00134.00192.00338.52143.3237.052.803.101.101.901.502.202.001.601.00NANANANA
Other Grant Revenue, Grant -2.00NANANA5.003.00NANANANANANANANANANANANANANANANANANANANANANA
Collaboration Arrangement Including Arrangements With Affiliate 20.0030.0023.0010.00290.00100.0035.0015.0014.0019.0018.0010.0029.5012.2229.004.0010.5513.34NANANANANANANANANANA
Product Sales 2793.001757.00293.001828.004859.003120.004531.005925.006935.004810.004197.001733.00NANANANANANANANANANANANANANANANA
Grant -2.0044.0028.0024.00-65.00144.00183.00126.00262.00140.00139.00194.00341.37145.6937.913.933.503.713.051.912.605.093.021.58NANANANA
Product And Service Other 18.0074.00NANA225.00244.00NANANANANANANANANANANANANANANANANANANANANANA
Product Sales, 614.00103.0060.00576.002221.001045.001390.002076.003806.001688.001056.00284.00NANANANANANANANANANANANANANANANA
Product Sales,US 804.00913.002.001.001025.00985.001450.00945.00745.001197.002093.001358.00NANANANANANANANANANANANANANANANA
Product Sales, Rest Of The World 1375.00741.00231.001251.001613.001090.001691.002904.002384.001925.001048.0091.00NANANANANANANANANANANANANANANANA

Plots across concepts


IncomeStatement
Operating Income Loss
Expenses
Income Tax Expense Benefit
Balance Sheet
Finite Lived Intangible Assets Net
Assets
Goodwill
Current Assets
Other Assets Current
NonCurrent Assets
Finite Lived Intangible Assets Net
Liabilities
Operating Lease Liability
Current Liabilities
Operating Lease Liability Current
Stockholders Equity
Accumulated Other Comprehensive Income Loss Net Of Tax
CashFlow
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInOperatingActivities
Increase Decrease In Accounts Receivable
NetCashProvidedByUsedInInvestingActivities
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInFinancingActivities
Net Cash Provided By Used In Financing Activities
Shares
Common Stock Shares Issued
OperatingLeaseLiability
Operating Lease Liability Current
LesseeOperatingLeaseLiabilityPaymentsDue
Lessee Operating Lease Liability Undiscounted Excess Amount
InventoryNet
Inventory Work In Process Net Of Reserves

Line plots across dimensions of each concept