OPK


Line plots across dimensions of each concept
Line plots across concepts
Tables

Table of contents



us-gaap:CommonStockValue

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:AllocatedShareBasedCompensationExpense

us-gaap:ComprehensiveIncomeNetOfTax

us-gaap:ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest
us-gaap:ProductOrService
us-gaap:CostOfGoodsAndServicesSold
us-gaap:DisposalGroupClassification, us-gaap:IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperations, us-gaap:SubsequentEventType
us-gaap:DisposalGroupNotDiscontinuedOperationGainLossOnDisposal

us-gaap:GainLossOnInvestments
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments

us-gaap:IncomeTaxExpenseBenefit

us-gaap:IncomeTaxesPaidNet

us-gaap:InterestPaidNet

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:NonoperatingIncomeExpense

us-gaap:OperatingExpenses

us-gaap:OperatingIncomeLoss
us-gaap:ConsolidationItems
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:ProfitLoss
us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:ResearchAndDevelopmentExpense

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ConsolidationItems, us-gaap:ProductOrService, us-gaap:StatementBusinessSegments
us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement
us-gaap:ProductOrService
us-gaap:ProductOrService, us-gaap:DebtInstrument
us-gaap:StatementGeographical

us-gaap:SellingGeneralAndAdministrativeExpense

us-gaap:Assets
us-gaap:ConsolidationItems
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments
us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:Liabilities
us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:StockholdersEquity
us-gaap:BusinessAcquisition
us-gaap:StatementEquityComponents

us-gaap:AssetsCurrent

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:AccountsReceivableNetCurrent

us-gaap:InventoryNet

us-gaap:InventoryFinishedGoods

us-gaap:OtherAssetsCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:AmortizationOfIntangibleAssets

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:LongTermInvestments

us-gaap:Goodwill
us-gaap:BusinessAcquisition
us-gaap:BusinessAcquisition, us-gaap:StatementBusinessSegments
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill
us-gaap:IndefiniteLivedIntangibleAssetsByMajorClass

us-gaap:FiniteLivedIntangibleAssetsNet

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:OtherAssetsNoncurrent

us-gaap:EquitySecuritiesFvNi
us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:AccountsPayableCurrent

us-gaap:AccruedLiabilitiesCurrent

us-gaap:ContractWithCustomerLiabilityCurrent

us-gaap:LiabilitiesCurrent
us-gaap:LongtermDebtType
us-gaap:LongTermDebtCurrent

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OtherAccruedLiabilitiesCurrent

us-gaap:LiabilitiesNoncurrent

us-gaap:LongTermDebt
us-gaap:BalanceSheetLocation
us-gaap:CreditFacility, us-gaap:DebtInstrument, us-gaap:LongtermDebtType
us-gaap:DebtInstrument, us-gaap:LongtermDebtType
us-gaap:LongtermDebtType

us-gaap:LongTermDebtNoncurrent
us-gaap:LongtermDebtType

us-gaap:DeferredIncomeTaxLiabilitiesNet

us-gaap:OtherLiabilitiesNoncurrent
us-gaap:LongtermDebtType

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive

us-gaap:OperatingLeaseLiability

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:StockholdersEquity
us-gaap:BusinessAcquisition
us-gaap:StatementEquityComponents

us-gaap:StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
us-gaap:StatementEquityComponents

us-gaap:CommonStockValue

us-gaap:AdditionalPaidInCapital

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax

us-gaap:TreasuryStockValue

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
us-gaap:StatementEquityComponents

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:AmortizationOfFinancingCosts
us-gaap:LongtermDebtType

us-gaap:DeferredIncomeTaxExpenseBenefit

us-gaap:DepreciationDepletionAndAmortization
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:IncreaseDecreaseInAccountsPayable

us-gaap:IncreaseDecreaseInAccountsReceivable

us-gaap:IncreaseDecreaseInInventories

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:ProfitLoss
us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:ShareBasedCompensation

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:PaymentsToAcquireProductiveAssets

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:DeferredTaxLiabilities
us-gaap:BalanceSheetLocation

us-gaap:UnrecognizedTaxBenefits

us-gaap:DeferredTaxAssetsValuationAllowance
us-gaap:ProductOrService
opk:AllowanceForDoubtfulAccountsProvisionForAllowanceAsPercentOfGrossSales
us-gaap:ProductOrService
opk:AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments
us-gaap:ProductOrService, us-gaap:ValuationAllowancesAndReservesType
opk:COVID19TestType
opk:COVID19NumberOfTestsPerformed

opk:COVID19PercentOfTotalTestVolume
opk:TestingType
opk:ChangeInTestingVolumePercent
us-gaap:StatementBusinessSegments
us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:SubsequentEventType
opk:CollaborativeArrangementDevelopmentMilestonePayment
us-gaap:CounterpartyName, us-gaap:SubsequentEventType
opk:CollaborativeArrangementPercentOfOutstandingShares
us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:SubsequentEventType
opk:CollaborativeArrangementSalesMilestonePayment
us-gaap:CounterpartyName, us-gaap:SubsequentEventType
opk:CollaborativeArrangementUpfrontPayment
us-gaap:DebtInstrument, us-gaap:LongtermDebtType
opk:GainLossOnConversionOfDebt

opk:IncomeLossfromContinuingOperationsBeforeInvestmentsinInvesteesExtraordinaryItemsNoncontrollingInterestNetofTax

opk:IncreaseDecreaseInEquitySecuritiesFVNIAndDerivativeInstruments
us-gaap:ProductOrService
opk:IncreaseDecreaseInRevenueFromContractWithCustomerExcludingAssessedTax

opk:IncreaseDecreaseinForeignCurrencyMeasurement

opk:InterestExpenseNonoperating

opk:InterestIncomeNonoperating

opk:NumberofSalesEmployees

opk:PaymentsForLeases
us-gaap:DebtInstrument, us-gaap:LongtermDebtType
opk:ProceedsFromConvertibleDebtConversionFee
opk:Milestone, us-gaap:CounterpartyName
opk:ProceedsFromDevelopmentAndLicenseAgreementMilestonePayment
opk:Milestone, us-gaap:CounterpartyName
opk:ProceedsFromDevelopmentAndLicenseAgreementUpfrontPayment
us-gaap:CounterpartyName
us-gaap:LongtermDebtType
us-gaap:AmortizationOfDebtDiscountPremium
us-gaap:LongtermDebtType
us-gaap:AmortizationOfFinancingCostsAndDiscounts

us-gaap:BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1
us-gaap:ConcentrationRiskByBenchmark, us-gaap:ConcentrationRiskByType
us-gaap:ConcentrationRiskPercentage1
us-gaap:MajorCustomers, us-gaap:ConcentrationRiskByBenchmark, us-gaap:ConcentrationRiskByType

us-gaap:ContractWithCustomerLiabilityRevenueRecognized
us-gaap:ProductOrService

us-gaap:ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod
us-gaap:DebtInstrument, us-gaap:LongtermDebtType
us-gaap:DebtConversionConvertedInstrumentAmount1

us-gaap:Depreciation
us-gaap:DerivativeInstrumentRisk, us-gaap:HedgingDesignation
us-gaap:DerivativeGainLossOnDerivativeNet
us-gaap:HedgingDesignation

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:EquitySecuritiesFvNiRealizedGainLoss

us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
us-gaap:FairValueByLiabilityClass
us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings
us-gaap:FairValueByLiabilityClass
us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases

us-gaap:FinanceLeaseInterestExpense

us-gaap:FinanceLeaseInterestPaymentOnLiability

us-gaap:FinanceLeasePrincipalPayments

us-gaap:GainLossOnDerivativeInstrumentsNetPretax

us-gaap:GainLossOnDispositionOfAssets1

us-gaap:GainLossOnSaleOfInvestments

us-gaap:GoodwillForeignCurrencyTranslationGainLoss
us-gaap:BusinessAcquisition, us-gaap:StatementBusinessSegments

us-gaap:IncomeLossFromEquityMethodInvestments

us-gaap:IncreaseDecreaseInAccruedLiabilities

us-gaap:IncreaseDecreaseInContractWithCustomerLiability

us-gaap:IncreaseDecreaseInOtherOperatingAssets

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:InventoryWriteDown
us-gaap:LitigationStatus
us-gaap:LitigationSettlementAmountAwardedToOtherParty
us-gaap:LitigationStatus, us-gaap:SubsequentEventType

us-gaap:OperatingLeaseCost

us-gaap:OperatingLeasePayments

us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent

us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
us-gaap:StatementEquityComponents

us-gaap:PaidInKindInterest
us-gaap:DebtInstrument
us-gaap:ProceedsFromIssuanceOfDebt

us-gaap:ProceedsFromIssuanceOrSaleOfEquity

us-gaap:ProceedsFromLinesOfCredit

us-gaap:ProceedsFromSaleMaturityAndCollectionsOfInvestments

us-gaap:ProceedsFromSaleOfPropertyPlantAndEquipment

us-gaap:ProvisionForDoubtfulAccounts
us-gaap:ProductOrService
us-gaap:ProductOrService, us-gaap:ValuationAllowancesAndReservesType

us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty

us-gaap:RepaymentsOfLinesOfCredit

us-gaap:StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
us-gaap:StatementEquityComponents

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised
us-gaap:StatementEquityComponents
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
us-gaap:VariableInterestEntityOwnershipPercentage

us-gaap:VariableLeaseCost

opk:AccruedClinicalTrialsCurrent

opk:AccruedCommitmentsandContingenciesCurrent

opk:AccruedExpensePayorOverpaymentReimbursementLiability

opk:BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
opk:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsVested

opk:DeferredTaxAssetsOperatingLeaseAsset

opk:DeferredTaxLiabilitiesConvertibleDebt

opk:DeferredTaxLiabilitiesNetBeforeValuationAllowance

opk:EquityMethodInvestmentExcludingVariableInterestEntity

opk:EquityMethodInvestmentExcludingVariableInterestEntityUnderlyingEquityinNetAssets

opk:EquityMethodInvestmentVariableInterestEntity

opk:EquityMethodInvestmentVariableInterestEntityUnderlyingEquityInNetAssets

opk:EquityMethodInvestmentVariableInterestEntityUnderlyingEquityinNetAssets
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
opk:EquitySecurityFVNIOwnershipPercent

opk:FinanceLeaseLiabilityPaymentsDueAfterYearFour

opk:InProcessResearchandDevelopment

opk:InventoryReceivedNotInvoicedCurrent

opk:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour

opk:LineofCreditandNotesandLoansPayableCurrent

opk:MortgagesAndOtherDebtsPayable

opk:StockOptionandWarrantInvestments

opk:TaxesRecoverableCurrent

us-gaap:AccountsAndOtherReceivablesNetCurrent

us-gaap:AccountsReceivableGrossCurrent

us-gaap:AccruedEmployeeBenefitsCurrent

us-gaap:AccruedProfessionalFeesCurrent
us-gaap:ProductOrService
us-gaap:AllowanceForDoubtfulAccountsReceivable
us-gaap:ProductOrService, us-gaap:ValuationAllowancesAndReservesType

us-gaap:AllowanceForDoubtfulAccountsReceivableCurrent

us-gaap:AssetsFairValueDisclosure
us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:AssetsHeldForSaleNotPartOfDisposalGroup

us-gaap:BusinessCombinationContingentConsiderationLiability
us-gaap:BalanceSheetLocation
us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:BusinessCombinationContingentConsiderationLiabilityCurrent

us-gaap:BusinessCombinationContingentConsiderationLiabilityNoncurrent
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights

us-gaap:ContractWithCustomerLiability

us-gaap:ContractWithCustomerLiabilityNoncurrent

us-gaap:ConvertibleLongTermNotesPayable
us-gaap:LongtermDebtType
us-gaap:DebtInstrumentCarryingAmount
us-gaap:LongtermDebtType
us-gaap:DebtInstrumentUnamortizedDiscount
us-gaap:BusinessAcquisition
us-gaap:DebtWeightedAverageInterestRate
us-gaap:LongtermDebtType
us-gaap:LongtermDebtType
us-gaap:DeferredFinanceCostsNet

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredTaxAssetIntraEntityTransferAssetOtherThanInventory

us-gaap:DeferredTaxAssetsEquityMethodInvestments

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsDomestic

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsForeign

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal

us-gaap:DeferredTaxAssetsOtherTaxCarryforwards

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsForeign

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch

us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsDeferredRent

us-gaap:DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets

us-gaap:DeferredTaxLiabilitiesLeasingArrangements

us-gaap:DeferredTaxLiabilitiesOther

us-gaap:DeferredTaxLiabilitiesPropertyPlantAndEquipment

us-gaap:DerivativeAssets
us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:FinancialInstrument
us-gaap:FinancialInstrument

us-gaap:DerivativeFairValueOfDerivativeAsset
us-gaap:BalanceSheetLocation, us-gaap:DerivativeInstrumentRisk, us-gaap:HedgingDesignation
us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:BalanceSheetLocation, us-gaap:DerivativeInstrumentRisk, us-gaap:HedgingDesignation
us-gaap:DerivativeFairValueOfDerivativeLiability
us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:FinancialInstrument
us-gaap:DerivativeLiabilities
us-gaap:FinancialInstrument

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
us-gaap:EquityMethodInvestmentOwnershipPercentage
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName, us-gaap:InvestmentsByConsolidatedAndNonconsolidatedEntities

us-gaap:EquityMethodInvestmentQuotedMarketValue

us-gaap:EquityMethodInvestmentUnderlyingEquityInNetAssets

us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount
us-gaap:FairValueByLiabilityClass
us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiabilityCurrent

us-gaap:FinanceLeaseLiabilityNoncurrent

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueYearFive

us-gaap:FinanceLeaseLiabilityPaymentsDueYearFour

us-gaap:FinanceLeaseLiabilityPaymentsDueYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueYearTwo

us-gaap:FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount

us-gaap:FinanceLeaseRightOfUseAsset

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent

us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
us-gaap:FiniteLivedIntangibleAssetsByMajorClass
us-gaap:FiniteLivedIntangibleAssetsGross

us-gaap:GoodwillImpairedAccumulatedImpairmentLoss

us-gaap:InventoryRawMaterials

us-gaap:InventoryValuationReserves

us-gaap:InventoryWorkInProcess

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear

us-gaap:LiabilitiesFairValueDisclosure
us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent

us-gaap:LineOfCredit
us-gaap:LineOfCreditFacility
us-gaap:CreditFacility, us-gaap:DebtInstrument, us-gaap:LongtermDebtType
us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity

us-gaap:LinesOfCreditCurrent
us-gaap:Range, us-gaap:BusinessAcquisition
us-gaap:LongTermDebtPercentageBearingVariableInterestRate
us-gaap:CreditFacility, us-gaap:DebtInstrument, us-gaap:LongtermDebtType
us-gaap:LongTermLineOfCredit
us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:LongtermDebtType
us-gaap:NotesPayableFairValueDisclosure
us-gaap:FairValueByMeasurementBasis, us-gaap:LongtermDebtType
us-gaap:LongtermDebtType

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent
us-gaap:IncomeTaxAuthority
us-gaap:OperatingLossCarryforwards

us-gaap:OperatingLossCarryforwardsValuationAllowance

us-gaap:OtherInventorySupplies

us-gaap:OtherLiabilitiesAndDeferredRevenueNoncurrent

us-gaap:PrepaidInsurance

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization
us-gaap:StatementGeographical
us-gaap:PropertyPlantAndEquipmentByType
us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization

us-gaap:PurchaseObligation

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1

us-gaap:SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit

us-gaap:Supplies
us-gaap:TaxCreditCarryforward
us-gaap:TaxCreditCarryforwardAmount

us-gaap:UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued

us-gaap:UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
us-gaap:ValuationAllowancesAndReservesType
us-gaap:ValuationAllowancesAndReservesBalance

Plots across concepts


IncomeStatement
Net Income Loss
Expenses
Other Nonoperating Income Expense
Balance Sheet
Operating Lease Right Of Use Asset
Assets
Derivative Assets
Current Assets
Other Assets Current
NonCurrent Assets
Long Term Investments
Liabilities
Operating Lease Liability
Current Liabilities
Contract With Customer Liability Current
Noncurrent Liabilities
Long Term Debt Noncurrent
Stockholders Equity
Retained Earnings Accumulated Deficit
CashFlow
Net Income Loss
NetCashProvidedByUsedInOperatingActivities
Increase Decrease In Accounts Payable
NetCashProvidedByUsedInInvestingActivities
Net Cash Provided By Used In Investing Activities
Shares
Weighted Average Number Of Share Outstanding Basic And Diluted
OperatingLeaseLiability
Operating Lease Liability Current
NonoperatingIncomeExpense
Nonoperating Income Expense
LesseeOperatingLeaseLiabilityPaymentsDue
Lessee Operating Lease Liability Payments Due Year Four
FiniteLivedIntangibleAssets
Finite Lived Intangible Assets Accumulated Amortization
InventoryNet
Inventory Finished Goods
AccountsReceivable
Allowance For Doubtful Accounts Receivable Current

Tables

  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:CommonStockValue ███████▇▇▇▆▆▆▆▆▆▆▆▆▆▅▅▅▅▄▄▃▃▃▃▃▃▂▂▁▁6.8986.7076.7066.7066.7046.7046.7046.1626.1626.1625.8695.6045.6025.65.65.65.65.5965.5865.5815.4835.485.4625.4594.6464.5934.3344.3294.2714.1544.1484.0893.3913.3883.0562.982
us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding 646.996891NANANA640.578794NANANANANANANA559.541NANANA564.164NANA552.229557.040435NANA514.32057462.253161NANA427.577102NANANANANANANANA
us-gaap:WeightedAverageNumberOfSharesOutstandingBasic 646.996891NANANA640.578794NANANANANANANA559.541253NANANA559.34754NANA552.229266547.559NANA500.562254462.253NANA427.577102NANANANANANANANA
us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted NA640.8532NA640.699982640.578794640.578794NA586.351045586.351045586.344207NA559.786382559.541253559.473838NA559.405309NA558.434153NA552.229266NA545.823434NANA462.253161446.480884NA427.577102413.339679412.909809NA360.638527336.732215312.932561NA298.103882
 us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities us-gaap:CommonStock▁█64.29288274.62327NA73.412869.50551369.339603NA69.0724368.93340249.702266NA0.29212316.52031416.570675NA1.016091.2710262.623001NA9.175105NA6.052199NANA11.26158217.489421NA29.87411229.13252729.874112NA35.15796629.70183830.119145NA26.022072
us-gaap:EarningsPerShareBasic -0.03NANANA0.05NANANANANANANA-0.01NA-0.38-0.08-0.03-0.06-0.02-0.030.03-0.020.00.26-0.09-0.26-0.12-0.11-0.06-0.11NANANANANANA
us-gaap:EarningsPerShareDiluted -0.03NANANA0.05NANANANANANANA-0.01NA-0.38-0.08-0.04-0.06-0.04-0.030.02-0.020.00.25-0.09-0.26-0.12-0.11-0.08-0.11NANANANANANA
us-gaap:EarningsPerShareBasicAndDiluted NA0.050.050.040.05-0.09-0.18-0.11-0.1-0.14-0.13-0.05-0.01-0.08-0.38-0.08NA-0.06-0.030000000000000002-0.03NA-0.02NANA-0.09-0.26-0.12-0.11-0.06-0.11-0.04-0.17-0.01-0.110.0-0.03
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
 COGS Ratio us-gaap:ProductOrService us-gaap:Product█▇▅▄▅▆▆▃▄▂▂▂▄▄▇▁▄35.66333.94530.81928.70229.35631.07432.04126.16128.6825.30125.34325.39528.52327.85133.76722.79528.966NANANANANANANANANANANANANANANANANANANA
 COGS Ratio us-gaap:ProductOrService us-gaap:Service▆█▇▆▃▂▂▂▂▂▂▃▃▃▁▂▃397.197506.951457.933382.498250.971170.839177.946181.139178.458178.891183.068202.811216.055211.315119.377200.876233.912NANANANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
 TTM Greenblatt ROC _ _▆██▇▇▅▂▅▅▄▃▅▆▅▁▄▅▅▅▅▇▅▆▆▅▄▅▅▅▅▅▆▆▆▆▆5.57138.43749.35621.93927.179-40.762-112.464-39.011-47.26-75.318-90.013-33.464-5.108-42.611-153.622-58.29-26.443-41.707-50.4-23.62328.266-27.518-7.934-8.223-25.409-56.914-32.454-48.201-34.885-30.277-35.866-19.01-17.983-6.773-1.064-9.369
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:AllocatedShareBasedCompensationExpense █▁3.52.6NA2.81.62.5NA3.43.14.5NA5.15.65.9NA6.56.19.7NANANANANANANANANANANANANANA1.85.21.81.1
us-gaap:ComprehensiveIncomeNetOfTax ▁█-12.82322.008NANA38.138-67.249NANANANANANANANANANANA-28.939NA-7.839.212-6.5510.058126.134-44.142-122.223-56.666-57.672-26.575-46.57-16.619-59.591-8.657-33.898-2.756-7.924
us-gaap:ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest NANANA32.01838.138-67.249NA-70.43-56.928-83.86-83.064-27.789-18.666-43.125-209.011-37.795-6.645-32.447-24.385-7.839.212-6.5510.058126.134-44.617-123.148-57.157-59.017-27.172-47.11NANANANANANA
 us-gaap:CostOfGoodsAndServicesSold us-gaap:ProductOrService us-gaap:Product█▇▄▃▄▃▃▂▁▁▁▁▂▂▃▃▁25.10124.07817.79917.48117.85717.37117.40415.57314.14514.15614.07313.60915.65214.64816.73616.10713.505NANANANANANANANANANANANANANANANANANANA
 us-gaap:CostOfGoodsAndServicesSold us-gaap:ProductOrService us-gaap:Service▆█▇▅▂▁▁▁▁▁▁▁▁▂▂▁▂267.807339.429300.926255.292144.794122.887124.877126.348130.078129.903135.458137.347134.408139.441139.883135.203143.901NANANANANANANANANANANANANANANANANANANA
 us-gaap:DisposalGroupNotDiscontinuedOperationGainLossOnDisposal us-gaap:DisposalGroupClassification,us-gaap:IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperations,us-gaap:SubsequentEventType us-gaap:DisposalGroupDisposedOfBySaleNotDiscontinuedOperations,opk:WaterfordIrelandFacility,us-gaap:SubsequentEventNANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:GainLossOnInvestments █████████▆▅▆▁▆▅▄▃▆▆▇▆▆▇▅▇▆▇██▆-0.067-0.043-0.047-0.11-0.189-0.134-0.481-0.294-0.271-1.854-2.955-1.874-7.213-2.456-2.7-4.013-5.628-2.131-2.505-0.814-1.988-2.345-1.038-3.502-0.804-1.761-1.101-0.06-0.37-2.056NANA-2.371-3.89-0.598-0.468
 us-gaap:GainLossOnInvestments us-gaap:ConsolidationItems,us-gaap:StatementBusinessSegments us-gaap:OperatingSegments,opk:Pharmaceutical████▇▇▇▇▇▆█▆▁▆▆▄▃▆▆██▆▇▄▇▆▇█▇▆-0.067-0.043-0.047-0.11-0.189-0.134-0.481-0.294-0.271-1.854-0.107-1.603-6.942-2.172-1.862-3.661-5.309-1.814-2.0220.3990.391-2.05-1.038-3.502-0.804-1.761-1.101-0.06-0.37-2.056NANANANANANA
us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments ▆▇█▇█▄▂▄▄▄▃▅▆▅▁▄▆▅▅▅█▅▆█▅▂▄▅▅▅▆▄▆▅▆▆-11.36531.68145.94120.64939.92-57.827-108.445-59.944-58.451-78.125-101.405-37.3443.029-41.55-150.041-66.834-22.86-35.808-42.644-34.15133.389-30.139-23.81638.771-42.186-110.767-53.346-49.66-25.606-42.421-14.421-57.911-1.057-30.829-10.083-9.489
us-gaap:IncomeTaxExpenseBenefit ▅▅▆▅▅▅▅▅▅▅▄▅▅▅█▄▅▅▄▄▆▄▄▁▅▅▅▅▅▅▅▅▅▅▅▅4.7540.5613.596-3.1786.0281.1713.4241.7691.0840.783-28.289-11.5632.017-0.89261.164-24.405-10.96-6.944-31.489-19.98815.868-20.506-26.457-92.9780.2515.509-0.9850.2940.1010.614-0.5861.290.9250.043-9.715-0.128
us-gaap:IncomeTaxesPaidNet ▇▇▇▇▇▇▇▇▇▇▆▇█▇▇▇█▇▁▇█▇█▇▇▇▇▇▇▇▇▇▇▇▇▇2.221.47-1.0510.356-1.0070.799-0.4360.9711.111.022-5.293-1.3682.9592.292-0.4831.5783.4730.848-35.1670.8735.6671.5053.4960.6260.530.2270.388-0.230.4190.3771.0050.0740.36-0.1180.060.318
us-gaap:InterestPaidNet ▁▇▁▇▁▇▂█▇▁▁▂0.1944.6890.2515.0790.5665.0120.7895.6734.90.5110.4450.846NANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:NetIncomeLoss ▆████▄▁▃▄▃▃▅▆▄-16.18631.07832.29823.71733.703-59.132-112.35-62.007-59.806-80.762-76.07-27.655-6.201-43.114NANANANANANANANANANANANA-52.971-48.669-25.48-44.551-16.8-59.998-3.394-34.215-0.548-9.646
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▆████▄▁▃▄▃▃▅▆▄-16.18631.07832.29823.71733.703-59.132-112.35-62.007-59.806-80.762-76.071-27.655-6.201-43.114NANANANANANANANANANANANANANANANA-16.8-59.998-3.394-34.215NANA
us-gaap:NonoperatingIncomeExpense ▄▄▅▅▆▄▅▃▄▅▄▄▅▅▅▄▅▅▅▄▅▅▄█▄▁▃▅▅▄▆▂▆▃▅▅-16.936-6.756-3.415-1.2912.741-17.0654.019-20.933-11.191-2.807-11.392-3.888.1371.0613.581-8.5443.5835.8997.756-10.5285.123-2.621-15.88246.994-16.777-53.853-20.892-1.4599.279-12.14421.445-38.90116.926-24.056-0.371-0.12
us-gaap:OperatingExpenses ▇█▇▇▅▄▆▅▅▅▅▅▅▅▆▅▆▆▅▅▅▅▅▃▂▂▂▂▂▂▂▁▁▁▁▁436.837506.728445.318406.125274.028252.228336.807267.783273.628297.769311.866283.279268.793297.525347.321321.785340.656337.803325.889321.658328.834318.555284.126151.25767.83886.99857.98767.97458.4352.55156.55839.65141.80426.39217.12313.677
us-gaap:OperatingIncomeLoss ▆██▇▇▅▂▅▅▄▃▅▆▅▁▄▅▅▅▅▇▅▆▆▅▄▅▅▅▅▅▆▆▆▆▆5.57138.43749.35621.93927.179-40.762-112.464-39.011-47.26-75.318-90.013-33.464-5.108-42.611-153.622-58.29-26.443-41.707-50.4-23.62328.266-27.518-7.934-8.223-25.409-56.914-32.454-48.201-34.885-30.277-35.866-19.01-17.983-6.773-1.064-9.369
us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax NANA13.2268.3014.435-8.1176.704-8.4232.878-3.098-6.993-0.134-12.4654.8651.0788.55710.4952.592-10.2612.796-4.4326.943-9.076-1.452-0.694-3.852-3.307-3.1690.188-1.801-0.430.367-2.0850.323-0.2811.96
us-gaap:OtherNonoperatingIncomeExpense ▂▄▄▅▇▂▅▁▃▄▂▄▅▄▅▄▄▄▄▃▅▄▂▇▄▄▃▃▄▄█▂▅▄▄▄-11.783-0.9272.0644.74918.223-12.3329.086-15.47-5.8740.977-8.118-0.8248.5841.8937.3520.597-0.5333.0420.36-2.9725.970.546-9.00417.4820.76-1.508-5.132-2.7642.991.81722.758-7.7878.0272.331-0.371-0.12
us-gaap:ProfitLoss NANANA23.71733.703-59.132NA-62.007-59.806-80.762-76.07-27.655-6.201-43.114-213.905-46.442-17.528-30.995-13.661-14.97715.533-11.9781.603128.247-43.241-118.037-53.461-50.014-26.075-45.091-17.429-60.801-4.353-34.762-1.04-9.646
 us-gaap:ProfitLoss us-gaap:EquityMethodInvestmentNonconsolidatedInvestee us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees█▅▁▁4.2-10.1-24.2-24.6NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:ResearchAndDevelopmentExpense ▄▄▄▄▄▅▅▇▆█▇▇▆▇█▇▇▆▆▅▇▆▆▄▇▆▆▅▄▅▅▃▂▂▂▁18.22219.31517.45418.49317.60821.7623.03830.01728.28636.52933.32830.1629.21132.88734.24232.32932.59326.02227.61124.42431.34827.82225.47818.93729.5725.50325.82720.51716.23420.99423.3511.0859.5579.916.5783.621
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax ▇█▇▆▅▄▄▄▄▄▄▄▄▄▃▄▅▄▅▄▄▄▄▂▁▁▁▁▁▁▁▁▁▁▁▁442.408545.165494.676428.064301.207211.466224.344228.772226.368222.451221.852249.815263.685211.315160.983246.04292.601228.545339.935259.025266.012252.522221.81103.9191.9082.0692.062.4822.1531.972.6082.773.1883.0921.4170.1
us-gaap:SellingGeneralAndAdministrativeExpense ▇▇▆▆▅▅▅▅▅▆▆▅▅▆▇███▇▇▇█▆▄▂▂▁▁▁▁▁▁▁▁▁▁113.236112.286101.82499.89777.72176.13279.1380.54288.47595.15895.10484.07187.65391.519124.635131.336128.338136.685120.53124.845117.511128.001102.94755.24620.93717.44615.24314.0114.87413.81215.44513.57213.87912.42410.3677.322
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:Assets ▆▇▇▆▆▆▆▆▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇█▄▄▄▄▄▄▄▄▂▂▁▁2421.652519.5752473.0632371.2912323.7342232.5422309.2722369.5182456.2282575.3012451.0722480.9942530.952578.8942584.5562721.992768.6942760.0682766.6192800.0272774.0212793.2062799.6143015.8531525.4911512.2491267.6641295.2421327.0821355.6921391.5161382.982641.08653.935289.83250.022
us-gaap:Liabilities ▅▆▆▆▆▅▅▆▆▆▅▅▆▆▅▅▅▅▅▅▆▆▆█▅▅▄▃▃▄▄▄▃▃▁▁679.065823.061801.512747.521735.391683.923694.513727.589747.297812.564659.781692.351720.454755.63699.178632.954661.865653.098674.811694.635758.381795.332819.821046.485698.505699.676431.923407.898414.257524.443518.537515.056328.596334.15786.5579.371
us-gaap:LiabilitiesAndStockholdersEquity ▆▇▇▆▆▆▆▆▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇█▄▄▄▄▄▄▄▄▂▂▁▁2421.652519.5752473.0632371.2912323.7342232.5422309.2722369.5182456.2282575.3012451.0722480.9942530.952578.8942584.5562721.992768.6942760.0682766.6192800.0272774.0212793.2062799.6143015.8531525.4911512.2491267.6641295.2421327.0821355.6921391.5161382.982641.08653.935289.83250.022
us-gaap:StockholdersEquity NANA1671.551NANANA1614.759NANANA1791.291NANANA1843.623NANANA2046.433NANANA1979.7941970.768834.789819.902842.144893.257917.392835.22876.41870.727314.482320.817179.386146.265
 us-gaap:StockholdersEquity us-gaap:BusinessAcquisition opk:BioReference█▇▃▁1095.71077.11000.0968.0NANA885.2NANANANANANANANANANANANANANANA1000.0NANANANANANANANANANANANANA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:AccumulatedOtherComprehensiveIncomeNANA-4.225NANANA-22.07NANANA-20.131NANANA-0.528NANANA-27.009NANANANANANANANANANANANANANANANANA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:AdditionalPaidInCapitalNANA3152.694NANANA3142.993NANANA3004.422NANANA2889.256NANANA2845.096NANANANANANANANANANANANANANANA565.201NA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:CommonStockNANA6.706NANANA6.704NANANA5.869NANANA5.6NANANA5.586NANANANANANANANANANANANANANANA3.056NA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:RetainedEarningsNANA-1481.833NANANA-1511.077NANANA-1197.078NANANA-1048.914NANANA-775.329NANANANANANANANANANANANANANANA-388.77NA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:TreasuryStockNANA-1.791NANANA-1.791NANANA-1.791NANANA-1.791NANANA-1.911NANANANANANANANANANANANANANANA-7.457NA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:AssetsCurrent ▇█▇▆▅▄▄▄▅▆▄▄▄▅▅▆▆▆▆▇▇▆▆▇▄▅▂▂▂▃▃▃▃▃▁▁547.029599.049523.179428.109360.054274.457324.045292.842344.228435.237317.731289.817321.562349.346343.461430.556472.516459.932483.601502.067505.573453.532454.058517.416278.339394.025142.869163.148183.01205.272242.728241.277230.116237.68378.65787.985
us-gaap:CashAndCashEquivalentsAtCarryingValue ▂▂▂▁▁▁▂▂▃▅▃▁▂▃▂▃▃▃▄▄▄▄▅▅▅█▃▃▃▄▅▄▃▄▁▁65.75789.50372.21136.29421.61234.5385.45264.667111.115207.2596.47343.71880.38199.94391.499100.362130.53131.052168.733144.646156.015174.973193.598212.144221.217348.19296.907118.258134.01156.396185.798155.834119.061181.59627.36123.428
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents ▃▄▃▂▁▁▃▃▄█▄▂▃▄▄65.75789.50372.21136.29421.61234.5385.45264.667111.115207.2596.47343.71880.38199.94391.499NANANA168.733NANANANANANANANANANANANANANANANANA
us-gaap:AccountsReceivableNetCurrent ▇█▇▆▆▄▄▄▄▄▄▄▄▄▄▆▆▆▆▆▆▅▅▅▁▁▁▁▁▁▁▁▁▁▁▁265.856320.462286.314241.544214.352132.476134.617140.765148.287144.383143.907157.374152.777158.642165.516233.916251.747238.893220.284223.827213.372204.479193.875189.72526.9819.06419.96921.2123.11319.66419.76721.37222.22721.1721.16219.142
us-gaap:InventoryNet ▇█▇▆▄▃▃▃▃▂▂▂▂▃▃▂▃▃▃▂▂▂▂▂▁▁▁▁▁▁▁▁▁▁▁▁134.722159.104132.341111.87372.96558.69753.43450.10948.29344.6142.29943.37946.75349.81549.33346.95448.29347.49247.22843.18642.04640.57539.68140.69320.51918.32416.60416.66218.33418.86518.07919.51619.77823.02222.26121.488
us-gaap:InventoryFinishedGoods ██▇▆▄▄▄▄▄▃▂▂▂▄▃▄▄▃▂▂▂▂▂▂▂▂▁▁▁▁▂▂▂▃▃▃38.8739.28736.83130.26824.25923.72925.14222.13721.48118.89115.25914.92516.78322.13721.01222.88221.82219.73316.14314.0313.94414.7913.40413.85113.8314.34912.11611.35512.45512.8813.37414.77515.16919.17717.96317.75
us-gaap:OtherAssetsCurrent ▇▃▃▄█▇▇▂▂▃▂▂▃▃▂▂▂▂▄▁▁▁▁▂▂▂▂▂▂▃▃▂15.8775.0635.3097.54219.05615.78615.8393.3273.2344.5113.8474.2434.7644.373.8383.883.2873.8487.5080.8740.7760.3060.9032.3573.3883.3844.2122.5912.6135.6555.6534.304NANA4.75NA
us-gaap:PrepaidExpenseAndOtherAssetsCurrent ▄▃▃▄▅▅▅▄▄▄▃▄▄▄▄▅▄▄▄█▇▃▃▇▁▁▁▁▁▁▂▂▂▂▁▁47.62729.9832.31338.39851.12548.75450.54237.30136.53338.99435.05245.34641.65140.94637.11349.32441.94642.49547.35690.40878.50633.50526.90474.8549.6238.4459.3897.0187.55310.34719.08419.55119.02311.8957.8735.004
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:AmortizationOfIntangibleAssets ▄▄▄▄▄▄▄▅▅▅▅▅▅▅█▅▅▅▅▅▄▄▄▂▁▁▁▁▁▁▁▁▁▁▁▁12.57412.57712.63813.87914.93714.93815.3916.41216.41916.56216.53316.89917.22717.330.77818.02317.95317.917.0718.11615.77813.44313.9668.113.2362.6652.6152.7352.8262.7442.9412.792.6882.7142.0232.178
us-gaap:PropertyPlantAndEquipmentNet NA139.069140.554134.102130.54127.304127.111128.519137.106139.965144.674147.386150.156148.718146.557142.437133.355126.256122.831125.486128.274133.948131.798126.82223.40515.1216.41117.03617.34816.88117.02717.02716.57716.7516.52612.845
us-gaap:LongTermInvestments ▁▁▂▂▄▁▃▂▄▅▅▇█▇▇▅▆▆▇▇▆▆▆▆▃▄▄▄▆▆▅▄▄▅▂▂8.94510.4115.73114.32526.2610.66920.74611.69524.76732.29731.22842.73745.49741.28940.64232.19634.49537.28541.13938.78334.24935.21234.71634.69521.43422.3822.45326.84933.42835.69730.65324.6926.6928.54615.63614.998
us-gaap:Goodwill ▇▇▇▇▇▇▇▇▇▇▇██████▇▇▇▇███▃▃▃▃▃▃▃▃▁▁▁▁677.36676.162680.602675.795671.599669.582671.94695.798699.842698.522700.193713.629714.234719.891717.099715.573712.075705.99704.603700.526691.06746.961743.348761.234289.607223.219224.292224.769226.001226.062226.373222.3482.08682.70980.4549.738
us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill ▇▇█████▁▁▁▁▂▂▂▂▂▂▂▂▂▁▄▄▄▄▄▄▄▄▄▄▄1000.01000.01100.01100.01100.01100.01100.0635.0635.569635.561635.572646.339645.714646.386647.347648.377645.957645.058644.713646.97606.035793.626792.275812.723812.446793.0793.152793.214793.326793.339793.341793.312NANA11.546NA
us-gaap:FiniteLivedIntangibleAssetsNet ▅▅▅▅▅▅▅▆▆▆▆▆▇▇▇▇▇▇███▆▆▇▁▁▁▁▁▁▁▁▁▁▁▁445.515456.309475.002486.418499.125513.511528.962564.31581.306597.316614.452631.434648.541667.637683.835714.552731.134746.654763.976781.89804.445625.405638.152660.28794.24759.43262.64965.55369.05971.92174.53377.33379.77582.35495.78482.586
us-gaap:OperatingLeaseRightOfUseAsset ▆▇▇▆▇██▅▁▄36.34938.63137.73536.48538.46939.79339.3835.82629.6433.277NANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:OtherAssetsNoncurrent ▂▂▂▁▁▁▁▁▁▁▁▂▁▁▁▄▄▄▁▁▁▁▁█▁▁▁▁▁▁▁▁▁▁▁▁9.69.74510.065.8577.4877.0266.8885.5283.773.1267.2229.6525.2465.6275.61538.29939.16238.8935.7564.3054.3854.5225.267102.6766.0135.0735.8384.6734.916.526.8617.0032.7842.8632.7771.87
us-gaap:EquitySecuritiesFvNi ▁▁▃▃▇▂▅▂▆██▆▆7.4668.83714.13612.7224.7778.9918.879.12920.85627.72326.31322.18322.35NANANANANANANANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:AccountsPayableCurrent ▅█▅▄▃▃▃▄▃▃▃▄▄▄▄▄▃▄▃▃▃▄▄▄▁▁▁▁▁▁▁▁▁▁▁▁88.512162.69100.88365.68544.67155.86662.53777.29660.37651.08547.39565.61369.06164.22974.30766.53662.15374.55853.3658.54461.06273.43672.53577.96916.03910.4728.7448.84110.04114.69613.41413.63111.64611.28710.27.238
us-gaap:AccruedLiabilitiesCurrent ▆▇██▇▅▅▆▆▇▇▇▇▇▇▆▇▆▆▆▇▆▆▇▅▅▂▂▂▂▂▂▁▁▁▁187.172213.119240.869248.422210.111164.939164.925172.734198.382217.534203.513214.907200.992217.133215.102176.3206.403178.866197.955186.076209.848182.342167.899201.113149.843158.76360.91255.55454.96458.77265.87443.26931.04526.67324.65621.794
us-gaap:ContractWithCustomerLiabilityCurrent ▁▂▂▂▂▁▂▄▆██████8.415.03115.78314.09916.5710.45519.19630.95150.38865.28863.50361.73461.84661.37861.388NANANANANANANANANANANANANANANANANANANANANA
us-gaap:LiabilitiesCurrent ▆█▇▇▆▅▅▅▆█▆▆▆▆▆▅▆▅▅▅▆▅▅▇▄▄▂▂▂▂▂▁▁▁▁▁303.98403.93375.483335.889279.543245.087249.119270.138283.374396.058288.321317.83306.861318.077301.335258.948283.052264.951263.296254.511281.237267.232251.902357.59180.481182.83883.11176.84179.40284.591.8571.37759.46958.22452.38246.441
 us-gaap:LongTermDebtCurrent us-gaap:LongtermDebtType opk:NotesPayableAndOtherLongTermLiabilities▁▁▁▂▆▃▇▂█▇▇1.7641.7241.7491.9142.4151.9272.4941.9032.6492.522.56NANANANANANANANANANANANANANANANANANANANANANANANANA
 us-gaap:LongTermDebtCurrent us-gaap:LongtermDebtType us-gaap:NotesPayableOtherPayables█▁▅1.7641.7241.749NANANA2.292NANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:OperatingLeaseLiabilityCurrent ▂▂▁▁▂▄▄▅▆█10.10210.3059.0289.0810.29811.4812.03812.92113.37615.123NANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:OtherAccruedLiabilitiesCurrent ▇▇▇▇▆▇▆███▆▇▆▇█▅▅▄▆▄▄▃▃▂▂▁▂▂▂▂▂▁69.269.47778.43473.24656.88468.09658.8584.43581.90280.83662.29477.01165.42175.93179.36447.56750.18538.69558.1837.62236.31423.22423.74919.86415.23210.38914.65312.32114.20612.70515.8785.887NANA6.182NA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:LiabilitiesNoncurrent ▅▅▅▅▆▅▅▆▆▅▅▅▅▅▅▅▅▅▅▅▆▆▇█▆▆▄▄▄▅▅▅▄▄▁375.085419.131426.029411.632455.848438.836445.394457.451463.923416.506371.46374.521413.593437.553397.843374.006378.813388.147411.515440.124477.144528.1567.918688.895518.024516.838348.812331.057334.855439.943426.687443.679269.127275.93334.168NA
us-gaap:LongTermDebt ▁▇█205.676246.517251.205NANANA270.3NANANANANANANANANANANANANANANANANANANANANANANANANANANANA3.954
us-gaap:LongTermDebtNoncurrent ▇▆▆▇▇▆▇▇█▇█▂▃▂▂▂▂▂▁▄▃▄▄█▃▄▄▄▅▅▅▆3.973.3253.8374.014.2013.5383.9064.0914.54.3224.6541.1421.7041.4321.5671.1621.561.4620.7172.2431.8072.3662.5234.7352.1482.1852.4342.6272.9483.1013.273.35NANA5.15NA
us-gaap:DeferredIncomeTaxLiabilitiesNet ▄▄▄▂▂▂▂▁▁▁▁▄▆▆▆▂▅▇█136.416135.244137.208119.182118.979118.6118.717113.479113.334116.009115.193134.112148.255148.732148.729118.799142.212159.286165.331NANANA226.036NANANANANANANANANANANANANA
us-gaap:OtherLiabilitiesNoncurrent ▁▁▁▁▂▂▂▃▃▂▄▄▄▅▅▅▄▄▄▄▅▆▆▅██▄▄▅▄▄▅▂▂▁▁24.86626.71137.07245.03191.65377.76287.804111.959127.75178.165198.968183.812209.444233.622219.954226.617201.843189.576202.483204.094224.316275.812292.47236.476408.821410.165217.358216.174218.49215.142214.775234.76280.60379.51234.16832.93
us-gaap:OperatingLeaseLiabilityNoncurrent ▇█▇▆▆▆▆▄▁▂30.60532.39429.7628.22528.75928.66927.66523.31816.67318.621NANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo ▆▄█▁7.7227.4718.2326.777NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree ▂▁█▃5.75.5876.945.996NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour ▁▁█▇3.7263.7145.0034.788NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive NANA3.145NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive NANA14.768NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:StockholdersEquity NANA1671.551NANANA1614.759NANANA1791.291NANANA1843.623NANANA2046.433NANANA1979.7941970.768834.789819.902842.144893.257917.392835.22876.41870.727314.482320.817179.386146.265
 us-gaap:StockholdersEquity us-gaap:BusinessAcquisition opk:BioReference█▇▃▁1095.71077.11000.0968.0NANA885.2NANANANANANANANANANANANANANANA1000.0NANANANANANANANANANANANANA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:AccumulatedOtherComprehensiveIncomeNANA-4.225NANANA-22.07NANANA-20.131NANANA-0.528NANANA-27.009NANANANANANANANANANANANANANANANANA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:AdditionalPaidInCapitalNANA3152.694NANANA3142.993NANANA3004.422NANANA2889.256NANANA2845.096NANANANANANANANANANANANANANANA565.201NA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:CommonStockNANA6.706NANANA6.704NANANA5.869NANANA5.6NANANA5.586NANANANANANANANANANANANANANANA3.056NA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:RetainedEarningsNANA-1481.833NANANA-1511.077NANANA-1197.078NANANA-1048.914NANANA-775.329NANANANANANANANANANANANANANANA-388.77NA
 us-gaap:StockholdersEquity us-gaap:StatementEquityComponents us-gaap:TreasuryStockNANA-1.791NANANA-1.791NANANA-1.791NANANA-1.791NANANA-1.911NANANANANANANANANANANANANANANA-7.457NA
us-gaap:StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest ▇▇▆▆▆▆▆▆▇▇▇▇▇▇▇█████████▃▃▃▄▄▃▄▄▁▂▁1742.5851696.5141671.5511623.771588.3431548.6191614.7591641.9291708.9311762.7371791.2911788.6431810.4961823.2641885.3782089.0362106.8292106.972091.8082105.3922015.641997.8741979.7941969.368826.986812.573835.741887.344912.825831.249872.979867.926312.484319.778178.894NA
us-gaap:CommonStockValue ███████▇▇▇▆▆▆▆▆▆▆▆▆▆▅▅▅▅▄▄▃▃▃▃▃▃▂▂▁▁6.8986.7076.7066.7066.7046.7046.7046.1626.1626.1625.8695.6045.6025.65.65.65.65.5965.5865.5815.4835.485.4625.4594.6464.5934.3344.3294.2714.1544.1484.0893.3913.3883.0562.982
us-gaap:AdditionalPaidInCapital ██████████▇▇▇▇▇▇▇▇▇▇▇▇▇▇▄▄▄▄▄▃▃▃▂▂▁▁3214.3513155.6483152.6943150.4373147.033145.4443142.9933065.0593061.6313058.5093004.4222907.0172901.0862895.1912889.2562883.0262863.0252856.6452845.0962834.32736.8162728.2642705.3852696.421687.3891628.8181529.0961523.5481490.0711384.6941379.3831357.235742.097739.778565.201529.958
us-gaap:RetainedEarningsAccumulatedDeficit ▂▂▂▁▁▁▁▂▂▃▃▄▄▄▄▆▆▆▆▆▆▆▆▆▅▆▆▇▇▇▇▇████-1466.941-1450.755-1481.833-1514.131-1537.848-1571.551-1511.077-1398.727-1336.72-1276.914-1197.078-1109.049-1081.397-1075.197-1007.159-792.377-745.935-728.407-729.954-716.294-701.317-716.849-704.871-706.474-834.721-791.955-674.843-621.872-573.203-547.727-503.177-486.377-426.379-422.985-388.77-388.222
us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax ▅▄▆▃▂▁▂▁▃▂▃▄▄▆▆▅▄▂▂▃▂▃▂▃▃▃▄▅▆▇▇▇▇███-9.932-13.295-4.225-17.451-25.752-30.187-22.07-28.774-20.351-23.229-20.131-13.138-13.004-0.539-0.528-5.422-14.07-24.953-27.009-16.284-23.431-17.11-22.537-20.992-18.88-17.503-12.392-8.6970.3041.3993.4183.2372.838.0937.3569.004
us-gaap:TreasuryStockValue ▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▃▃▃▄▄▄▄███████1.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.9111.9111.9111.9111.9113.6453.6453.6454.0514.0514.0514.0517.37.3627.4577.4577.4577.4577.457
us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue ▄▃▂▃▁▂▂▄▃▆▇▇▇█3.462.6472.172.741.5862.4512.4143.4283.1224.4575.175.0775.5785.936NANANANANANANANANANANANANANANANA3.5720.4081.7985.205NANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:NetCashProvidedByUsedInOperatingActivities ▂▃▃▄▂▁▁▂▁▁▁▂▂▁▂▁▂▁▃▂▃▂▂▂▁█▂▂▂▂▂▂▂▂▂▂-15.45326.03734.25863.011-14.423-43.37-46.037-23.866-53.631-48.988-34.659-21.883-17.079-35.522.11-37.607-22.664-33.91930.306-31.89642.842-9.206-9.351-31.363-34.055238.793-24.761-21.077-15.495-29.046-26.05-11.472-5.925-14.745-5.728-1.927
us-gaap:NetCashProvidedByUsedInInvestingActivities ▅▆▅▆▅▆▆▆▆▆▆▅▅▆▅▅▅▅▅▇▅▅▅▆▁▆▆▆▆▆██▃▆▆▅-8.842-1.106-6.7445.501-11.465-5.619-3.756-2.191-3.191-4.132-2.882-11.571-6.52-5.146-13.954-16.301-9.97-6.442-6.47919.486-23.647-10.062-7.9377.174-98.095-0.363-0.799-1.545-3.067-0.26438.87345.292-53.199-0.6498.43-10.801
us-gaap:NetCashProvidedByUsedInFinancingActivities ▃▂▃▁▃▃▅▂▁█▆▃▃▄▃▃▄▃▃▃▂▃▃▃▃▃▃▃▃▃▃▃▃█▃▃0.265-7.1928.108-54.46112.888-1.61170.644-19.995-39.276163.87590.703-3.0054.0249.1914.22622.90231.7412.1741.7780.96-37.9860.053-0.17114.6944.6713.8124.1297.135-3.905-0.09617.0372.813-3.317169.6411.048-1.774
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect ▃▅▅▅▄▃▅▃▁█▆▃▄▅-23.74617.29235.91714.682-12.918-50.92220.785-46.448-96.135110.77752.755-36.663-19.5628.444NANANANANANANANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:AmortizationOfFinancingCosts ▂▂▂▂▂▂▃▂▁▃▂▂▂▂▂▂▂▂▂▂▂▂▂▃▂▄▂▂█▂▂▄▂▂▁▁0.2020.2220.2210.2150.2080.2030.4890.198-0.0970.4050.0320.0560.0560.0430.0560.0560.0560.0560.0620.1010.0370.0370.0370.280.1440.7510.10.11.630.1770.1770.650.1980.1450.00.0
us-gaap:DeferredIncomeTaxExpenseBenefit ▅▅▆▅▅▅▅▅▅▅▄▅▅▅█▄▅▅▄▄▆▄▄▁▅▅▅▅▅▅▅▅▅▅▅▅3.512-1.03313.6660.9460.4150.6132.2591.8970.52-0.352-20.605-12.5150.683-2.70962.458-23.327-13.803-9.236-30.502-21.98313.245-22.244-26.823-96.7130.00.0-1.0180.00.00.00.7960.405-0.70.098-9.9580.0
us-gaap:DepreciationDepletionAndAmortization ▆▆▆▇▇▇▇▇▇▇▇▇██████▇██▇▇▄▁▁▁▁▁▁▂▁▁▁▁▁20.57319.98920.06721.03622.26622.05222.52623.80523.66123.81623.90423.92124.76224.75725.41625.39425.55125.7323.96425.83224.5822.19922.17512.3994.1523.5253.6583.6784.0273.5644.5683.7683.4513.4292.7132.662
us-gaap:IncreaseDecreaseInAccountsPayable ▁█▇▆▄▅▄▆▅▅▄▅▅▄▅▅▄▆▅▅▄▅▆▃▅▅▅▅▅▅▅▅▅▅▅▅-73.88262.23133.89820.014-11.888-4.865-14.96117.719.1743.713-16.754-1.2372.114-10.2068.1582.574-10.119.539-3.678-2.936-12.856-0.34917.382-42.6054.9942.107-0.002-0.542-4.7871.479-0.4741.970.436-0.1031.5780.465
us-gaap:IncreaseDecreaseInAccountsReceivable ▂▆▆▅█▄▄▄▄▄▄▅▄▄▁▃▅▅▄▅▅▅▅▅▅▄▄▄▄▄▄▄▄▄▄▄-55.5935.23843.18225.71680.7760.763-4.119-7.6553.9590.439-12.6964.739-5.683-6.757-71.605-17.27113.09417.771-3.33710.5868.4649.92415.3819.24.7090.103-0.221-0.1813.7640.557-1.478-0.9281.0940.558-0.947-2.497
us-gaap:IncreaseDecreaseInInventories ▁▇▆█▅▅▄▄▄▄▄▃▄▄▄▃▄▄▄▄▄▄▄▄▄▄▄▄▄▄▄▄▃▄▄▄-24.09527.91217.07738.6613.0748.8312.593.3183.752.475-0.533-3.163-0.69-0.2045.268-2.1720.3930.053.8810.9631.6110.152-0.5283.150.6472.610.653-0.314-0.2631.676-0.940.261-2.6521.4391.3641.122
us-gaap:NetCashProvidedByUsedInOperatingActivities ▂▃▃▄▂▁▁▂▁▁▁▂▂▁▂▁▂▁▃▂▃▂▂▂▁█▂▂▂▂▂▂▂▂▂▂-15.45326.03734.25863.011-14.423-43.37-46.037-23.866-53.631-48.988-34.659-21.883-17.079-35.522.11-37.607-22.664-33.91930.306-31.89642.842-9.206-9.351-31.363-34.055238.793-24.761-21.077-15.495-29.046-26.05-11.472-5.925-14.745-5.728-1.927
us-gaap:NetIncomeLoss ▆████▄▁▃▄▃▃▅▆▄-16.18631.07832.29823.71733.703-59.132-112.35-62.007-59.806-80.762-76.07-27.655-6.201-43.114NANANANANANANANANANANANA-52.971-48.669-25.48-44.551-16.8-59.998-3.394-34.215-0.548-9.646
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▆████▄▁▃▄▃▃▅▆▄-16.18631.07832.29823.71733.703-59.132-112.35-62.007-59.806-80.762-76.071-27.655-6.201-43.114NANANANANANANANANANANANANANANANA-16.8-59.998-3.394-34.215NANA
us-gaap:ProfitLoss NANANA23.71733.703-59.132NA-62.007-59.806-80.762-76.07-27.655-6.201-43.114-213.905-46.442-17.528-30.995-13.661-14.97715.533-11.9781.603128.247-43.241-118.037-53.461-50.014-26.075-45.091-17.429-60.801-4.353-34.762-1.04-9.646
 us-gaap:ProfitLoss us-gaap:EquityMethodInvestmentNonconsolidatedInvestee us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees█▅▁▁4.2-10.1-24.2-24.6NANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANANA
us-gaap:ShareBasedCompensation ▂▂▂▂▁▂▂▂▂▃▃▃▃▃▃▄▃▅▄▄▄█▄▂▄▄▃▂▂▂▂▁▂▃▂▁3.462.6472.172.741.5862.4512.4143.4283.1224.4575.175.0775.5785.9366.0156.4926.1079.6937.7618.8348.79817.3078.3093.6756.7087.3824.6913.13.43.5793.5720.41.85.2051.851.1
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:NetCashProvidedByUsedInInvestingActivities ▅▆▅▆▅▆▆▆▆▆▆▅▅▆▅▅▅▅▅▇▅▅▅▆▁▆▆▆▆▆██▃▆▆▅-8.842-1.106-6.7445.501-11.465-5.619-3.756-2.191-3.191-4.132-2.882-11.571-6.52-5.146-13.954-16.301-9.97-6.442-6.47919.486-23.647-10.062-7.9377.174-98.095-0.363-0.799-1.545-3.067-0.26438.87345.292-53.199-0.6498.43-10.801
us-gaap:PaymentsToAcquireProductiveAssets ▅▅▄▅▆▃▃▂▂▂▂▆▄▄██▄▅▂▃▂▅▄▂▁▁▁▂▂▁▁▁▁▁▁▁8.9479.2456.7979.73611.5235.6263.8752.4343.52.9323.03512.0316.8195.97314.46315.2567.2689.5371.5324.1493.0549.8126.4242.9831.0760.3630.7991.4681.6060.8610.9710.9371.2990.7550.4080.656
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
us-gaap:NetCashProvidedByUsedInFinancingActivities ▃▂▃▁▃▃▅▂▁█▆▃▃▄▃▃▄▃▃▃▂▃▃▃▃▃▃▃▃▃▃▃▃█▃▃0.265-7.1928.108-54.46112.888-1.61170.644-19.995-39.276163.87590.703-3.0054.0249.1914.22622.90231.7412.1741.7780.96-37.9860.053-0.17114.6944.6713.8124.1297.135-3.905-0.09617.0372.813-3.317169.6411.048-1.774
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value6898000.06707000.06706000.06706000.06704000.06704000.06704000.06162000.06162000.06162000.05869000.05604000.05602000.05600000.05600000.05600000.05600000.05596000.05586000.05581000.05483000.05480000.05462000.05459000.04646000.04593000.04334000.04329000.04271000.04154000.04148000.04089000.03391000.03388000.03056000.02982000.02980000.02976000.02975000.02881000.02879000.02554000.0
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.30.30.30.30.30.30.30.30.30.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.30.30.30.30.30.30.30.30.50.51.11.21.31.31.31.91.83.3

Weighted Average Number Of Diluted Shares Outstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding


Weighted
Period End2021-06-302020-06-302018-06-302017-06-302016-09-302016-06-302015-09-302015-06-302014-09-302012-03-312011-03-31
Value646640559564552557514462427297261
Percentage of WeightedAverageNumberOfDilutedSharesOutstanding100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Weighted Average Number Of Shares Outstanding Basic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic


Weighted
Period End2021-06-302020-06-302018-06-302017-06-302016-09-302016-06-302015-09-302015-06-302014-09-30
Value646640559559552547500462427
Percentage of WeightedAverageNumberOfSharesOutstandingBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0

Weighted Average Number Of Share Outstanding Basic And Diluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted


Weighted
Period End2021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-03-312016-09-302016-03-312015-06-302015-03-312014-09-302014-06-302014-03-312013-09-302013-06-302013-03-312012-09-30
Value640640640640586586586559559559559558552545462446427413412360336312298
Percentage of WeightedAverageNumberOfShareOutstandingBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount

us-gaap:CommonStock


Antidilutive
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-03-312015-06-302015-03-312014-09-302014-06-302014-03-312013-09-302013-06-302013-03-312012-09-30
Value64747369696968490.29212316161.016091.2710262.6230019.1751056.052199111729292935293026
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Basic

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareBasic


Earnings
Period End2021-06-302020-06-302018-06-302017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312012-03-312011-12-312011-09-302011-06-302011-03-31
Value-0.030.05-0.01-0.38-0.08-0.03-0.06-0.02-0.030.03-0.0200.26-0.09-0.26-0.12-0.11-0.06-0.11-0.030.06-0.03-0.02-0.02
Percentage of EarningsPerShareBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Diluted

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareDiluted


Earnings
Period End2021-06-302020-06-302018-06-302017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312011-12-312011-09-302011-06-302011-03-31
Value-0.030.05-0.01-0.38-0.08-0.04-0.06-0.04-0.030.02-0.0200.25-0.09-0.26-0.12-0.11-0.08-0.110.06-0.03-0.02-0.02
Percentage of EarningsPerShareDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Basic And Diluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:EarningsPerShareBasicAndDiluted


Earnings
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-03-312016-12-312016-09-302016-03-312015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-312010-09-302010-06-30
Value0.050.050.040.05-0.09-0.18-0.11-0.1-0.14-0.13-0.05-0.01-0.08-0.38-0.08-0.06-0.03-0.03-0.02-0.09-0.26-0.12-0.11-0.06-0.11-0.04-0.17-0.01-0.110-0.03-0.04-0.030.07-0.03-0.020-0.03-0.03
Percentage of EarningsPerShareBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.00.0100.0100.0

Allocated Share Based Compensation Expense

us-gaap:AllocatedShareBasedCompensationExpense

us-gaap:AllocatedShareBasedCompensationExpense


Allocated
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-30
Value3.52.62.81.62.53.43.14.55.15.65.96.56.19.71.85.21.81.11.01.21.61.81.9
Percentage of AllocatedShareBasedCompensationExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.80.50.70.51.21.51.42.02.02.12.82.62.14.256.5168.2127.01100.00.00.00.00.00.0

Comprehensive Income Net Of Tax

us-gaap:ComprehensiveIncomeNetOfTax

us-gaap:ComprehensiveIncomeNetOfTax


Comprehensive
Period End2021-06-302021-03-312020-06-302020-03-312017-03-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-31
Value-12.8232238-67.249-28.939-7.839.212-6.5510.058126-44.142-122.223-56.666-57.672-26.575-46.57-16.619-59.591-8.657-33.898-2.756-7.9246.489-7.67218-11.559-5.628-6.846
Percentage of ComprehensiveIncomeNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2.94.012.7-31.8-12.7-3.03.5-2.60.0121.4-2313.5-5907.3-2750.8-2323.6-1234.3-2364.0-637.2-2151.3-271.5-1096.3-194.5-7924.00.00.00.00.00.00.0

Comprehensive Income Net Of Tax Including Portion Attributable To Noncontrolling Interest

us-gaap:ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest

us-gaap:ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest


Comprehensive
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-31
Value3238-67.249-70.43-56.928-83.86-83.064-27.789-18.666-43.125-209.011-37.795-6.645-32.447-24.385-7.839.212-6.5510.058126-44.617-123.148-57.157-59.017-27.172-47.11
Percentage of ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax7.512.7-31.8-30.8-25.1-37.7-37.4-11.1-7.1-20.4-129.8-15.4-2.3-14.2-7.2-3.03.5-2.60.0121.4-2338.4-5952.1-2774.6-2377.8-1262.1-2391.4

Cost Of Goods And Services Sold

us-gaap:CostOfGoodsAndServicesSold us-gaap:ProductOrService

us-gaap:CostOfGoodsAndServicesSold

us-gaap:Product


Cost
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value2524171717171715141414131514161613
Percentage of CostOfGoodsAndServicesSold100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.74.43.64.15.98.27.86.86.26.46.35.45.96.910.46.54.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product70.470.90.060.960.855.90.059.549.356.00.053.654.952.60.070.746.6

us-gaap:Service


Cost
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value267339300255144122124126130129135137134139139135143
Percentage of CostOfGoodsAndServicesSold1066.91409.71690.71460.4810.9707.4717.5811.3919.6917.7962.51009.2858.7951.9835.8839.41065.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax60.562.360.859.648.158.155.755.257.558.461.155.051.066.086.955.049.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Service67.467.00.066.757.771.90.069.872.972.60.067.762.266.00.067.361.5

Disposal Group Not Discontinued Operation Gain Loss On Disposal

us-gaap:DisposalGroupNotDiscontinuedOperationGainLossOnDisposal us-gaap:DisposalGroupClassification, us-gaap:IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperations, us-gaap:SubsequentEventType

us-gaap:DisposalGroupNotDiscontinuedOperationGainLossOnDisposal

us-gaap:DisposalGroupDisposedOfBySaleNotDiscontinuedOperations, opk:WaterfordIrelandFacility, us-gaap:SubsequentEvent


Disposal
Period End2021-09-30
Value32
Percentage of DisposalGroupNotDiscontinuedOperationGainLossOnDisposal100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:DisposalGroupDisposedOfBySaleNotDiscontinuedOperations opk:WaterfordIrelandFacility us-gaap:SubsequentEvent0.0

Gain Loss On Investments

us-gaap:GainLossOnInvestments

us-gaap:GainLossOnInvestments


Gain
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value-67000.0-43000.0-47000.0-110000.0-189000.0-134000.0-481000.0-294000.0-271000.0-1854000.0-2955000.0-1874000.0-7213000.0-2456000.0-2700000.0-4013000.0-5628000.0-2131000.0-2505000.0-814000.0-1988000.0-2345000.0-1038000.0-3502000.0-804000.0-1761000.0-1101000.0-60000.0-370000.0-2056000.0-2371000.0-3890000.0-598000.0-468000.0-475000.0-523000.0-414000.0-301000.0-451000.0-423000.0-31000.0-208000.0-244000.0
Percentage of GainLossOnInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-0.0-0.0-0.0-0.0-0.1-0.1-0.2-0.1-0.1-0.8-1.3-0.8-2.7-1.2-1.7-1.6-1.9-0.9-0.7-0.3-0.7-0.9-0.5-3.4-42.1-85.1-53.4-2.4-17.2-104.4-74.4-125.8-42.2-468.00.00.00.00.00.00.00.00.00.0

us-gaap:GainLossOnInvestments us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:OperatingSegments, opk:Pharmaceutical


Gain
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-31
Value-67000.0-43000.0-47000.0-110000.0-189000.0-134000.0-481000.0-294000.0-271000.0-1854000.0-107000.0-1603000.0-6942000.0-2172000.0-1862000.0-3661000.0-5309000.0-1814000.0-2022000.0399000.0391000.0-2050000.0-1038000.0-3502000.0-804000.0-1761000.0-1101000.0-60000.0-370000.0-2056000.0
Percentage of GainLossOnInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.03.685.596.288.469.091.294.385.180.7-49.0-19.787.4100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-0.0-0.0-0.0-0.0-0.1-0.1-0.2-0.1-0.1-0.8-0.0-0.6-2.6-1.0-1.2-1.5-1.8-0.8-0.60.20.1-0.8-0.5-3.4-42.1-85.1-53.4-2.4-17.2-104.4
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value-11.36531452039-57.827-108.445-59.944-58.451-78.125-101.405-37.3443.029-41.55-150.041-66.834-22.86-35.808-42.644-34.15133-30.139-23.81638-42.186-110.767-53.346-49.66-25.606-42.421-14.421-57.911-1.057-30.829-10.083-9.489-9.768-7.873-8.762-6.475-5.301-4.0930.944-4.541-5.917
Percentage of IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2.65.89.34.813.3-27.3-48.3-26.2-25.8-35.1-45.7-14.91.1-19.7-93.2-27.2-7.8-15.7-12.5-13.212.6-11.9-10.737.3-2211.0-5353.6-2589.6-2000.8-1189.3-2153.4-553.0-2090.6-33.2-997.1-711.6-9489.00.00.00.00.00.00.00.00.00.0

Income Tax Expense Benefit

us-gaap:IncomeTaxExpenseBenefit

us-gaap:IncomeTaxExpenseBenefit


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value4.7540.5613-3.1786.0281.1713.4241.7691.0840.783-28.289-11.5632.017-0.89261-24.405-10.96-6.944-31.489-19.98815-20.506-26.457-92.9780.2515.509-0.9850.2940.1010.614-0.5861.290.9250.043-9.715-0.1280.0020.215-19.557-0.027-0.0060.233-0.2020.0830.054
Percentage of IncomeTaxExpenseBenefit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.10.12.7-0.72.00.61.50.80.50.4-12.8-4.60.8-0.438.0-9.9-3.7-3.0-9.3-7.76.0-8.1-11.9-89.513.2266.3-47.811.84.731.2-22.546.629.01.4-685.6-128.00.00.00.00.00.00.00.00.00.0

Income Taxes Paid Net

us-gaap:IncomeTaxesPaidNet

us-gaap:IncomeTaxesPaidNet


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302010-12-312010-09-30
Value2220000.01470000.0-1051000.0356000.0-1007000.0799000.0-436000.0971000.01110000.01022000.0-5293000.0-1368000.02959000.02292000.0-483000.01578000.03473000.0848000.0-35167000.0873000.05667000.01505000.03496000.0626000.0530000.0227000.0388000.0-230000.0419000.0377000.01005000.074000.0360000.0-118000.060000.0318000.0203000.0-6000.0-17000.08000.0395000.0-228000.0
Percentage of IncomeTaxesPaidNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.50.3-0.20.1-0.30.4-0.20.40.50.5-2.4-0.51.11.1-0.30.61.20.4-10.30.32.10.61.60.627.811.018.8-9.319.519.138.52.711.3-3.84.2318.00.00.00.00.00.00.0

Interest Paid Net

us-gaap:InterestPaidNet

us-gaap:InterestPaidNet


Interest
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value0.1944.6890.2515.0790.5665.0120.7895.6734.90.5110.4450.846
Percentage of InterestPaidNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.00.90.11.20.22.40.42.52.20.20.20.3

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value-16.18631322333-59.132-112.35-62.007-59.806-80.762-76.07-27.655-6.201-43.114-52.971-48.669-25.48-44.551-16.8-59.998-3.394-34.215-0.548-9.646-10.245-8.61118-8.236-5.746-5.704-0.673-7.354-6.215
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.75.76.55.511.2-28.0-50.1-27.1-26.4-36.3-34.3-11.1-2.4-20.4-2571.4-1960.9-1183.5-2261.5-644.2-2166.0-106.5-1106.6-38.7-9646.00.00.00.00.00.00.00.00.00.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312013-12-312013-09-302013-06-302013-03-31
Value-16.18631322333-59.132-112.35-62.007-59.806-80.762-76.071-27.655-6.201-43.114-16.8-59.998-3.394-34.215
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.75.76.55.511.2-28.0-50.1-27.1-26.4-36.3-34.3-11.1-2.4-20.4-644.2-2166.0-106.5-1106.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Nonoperating Income Expense

us-gaap:NonoperatingIncomeExpense

us-gaap:NonoperatingIncomeExpense


Nonoperating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-16.936-6.756-3.415-1.2912-17.0654.019-20.933-11.191-2.807-11.392-3.888.1371.0613.581-8.5443.5835.8997.756-10.5285.123-2.621-15.88246-16.777-53.853-20.892-1.4599.279-12.14421-38.90116-24.056-0.371-0.12
Percentage of NonoperatingIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.8-1.2-0.7-0.34.2-8.11.8-9.2-4.9-1.3-5.1-1.63.10.52.2-3.51.22.62.3-4.11.9-1.0-7.245.2-879.3-2602.9-1014.2-58.8431.0-616.4822.3-1404.4530.9-778.0-26.2-120.0

Operating Expenses

us-gaap:OperatingExpenses

us-gaap:OperatingExpenses


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value4365064454062742523362672732973112832682973473213403373253213283182841516786576758525639412617131212108.5949.0936.9088.1416.5518.132
Percentage of OperatingExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax98.792.990.094.991.0119.3150.1117.1120.9133.9140.6113.4101.9140.8215.8130.8116.4147.895.9124.2123.6126.1128.1145.63555.54204.82814.92738.72713.92667.62168.61431.41311.3853.61208.413677.00.00.00.00.00.00.00.00.00.0

Operating Income Loss

us-gaap:OperatingIncomeLoss

us-gaap:OperatingIncomeLoss


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value5.57138492127-40.762-112.464-39.011-47.26-75.318-90.013-33.464-5.108-42.611-153.622-58.29-26.443-41.707-50.4-23.62328-27.518-7.934-8.223-25.409-56.914-32.454-48.201-34.885-30.277-35.866-19.01-17.983-6.773-1.064-9.369-9.341-8.84710-5.804-5.162-4.1360.741-4.221-5.527
Percentage of OperatingIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.37.110.05.19.0-19.3-50.1-17.1-20.9-33.9-40.6-13.4-1.9-20.2-95.4-23.7-9.0-18.2-14.8-9.110.6-10.9-3.6-7.9-1331.7-2750.8-1575.4-1942.0-1620.3-1536.9-1375.2-686.3-564.1-219.0-75.1-9369.00.00.00.00.00.00.00.00.00.0

us-gaap:OperatingIncomeLoss us-gaap:ConsolidationItems

us-gaap:CorporateNonSegment


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-10.719-9.42-11.618-9.808-7.76-8.503-10.253-8.416-10.691-12.272-17.775-5.445-8.748-11.645-14.548-12.219-12.878-15.969-10.627-8.128-17.453-23.833-12.068-11.562-12.905-9.979-8.168-6.384-7.038-6.137-7.08-6.606-5.762-5.025-5.978-3.804
Percentage of OperatingIncomeLoss-192.4-24.5-23.5-44.7-28.620.99.121.622.616.319.716.3171.327.39.521.048.738.321.134.4-61.786.6152.1140.650.817.525.213.220.220.319.734.832.074.2561.840.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2.4-1.7-2.3-2.3-2.6-4.0-4.6-3.7-4.7-5.5-8.0-2.2-3.3-5.5-9.0-5.0-4.4-7.0-3.1-3.1-6.6-9.4-5.4-11.1-676.4-482.3-396.5-257.2-326.9-311.5-271.5-238.5-180.7-162.5-421.9-3804.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:CorporateNonSegment0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:OperatingIncomeLoss us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:OperatingSegments, opk:Diagnostics


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value3067694640-18.133-45.414-16.363-28.013-33.569-27.318-11.0821.475-8.018-100.876-27.619-4.944-3.101-14.513.09810-2.3557.667-1.961-7.098-8.477-1.026-6.738-6.805-7.078-5.416-0.399-6.75-9.634-1.424-3.81
Percentage of OperatingIncomeLoss538.5174.3141.7210.5150.644.540.441.959.344.630.333.1-28.918.865.747.418.77.428.8-13.136.78.6-96.623.827.914.93.214.019.523.415.12.137.5142.2133.840.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.812.314.110.813.6-8.6-20.2-7.2-12.4-15.1-12.3-4.40.6-3.8-62.7-11.2-1.7-1.4-4.31.23.9-0.93.5-1.9-372.0-409.7-49.8-271.5-316.1-359.3-207.7-14.4-211.7-311.6-100.5-3810.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments opk:Diagnostics0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:OperatingSegments, opk:Pharmaceutical


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-13.71-19.157-8.973-14.425-5.996-14.126-56.797-14.232-8.556-29.477-44.92-16.9372.165-22.948-38.198-18.452-8.621-22.637-25.263-18.59335-1.33-3.5345.3-4.66-37.924-22.98-34.48-20.368-16.573-22.638-11.126-4.5288.483-1.725-1.755
Percentage of OperatingIncomeLoss-246.1-49.8-18.2-65.8-22.134.750.536.518.139.149.950.6-42.453.924.931.732.654.350.178.7125.04.844.5-64.518.366.670.871.558.454.763.158.525.2-125.2162.118.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.1-3.5-1.8-3.4-2.0-6.7-25.3-6.2-3.8-13.3-20.2-6.80.8-10.9-23.7-7.5-2.9-9.9-7.4-7.213.3-0.5-1.65.1-244.2-1833.0-1115.5-1389.2-946.0-841.3-868.0-401.7-142.0274.4-121.7-1755.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Other Comprehensive Income Loss Foreign Currency Transaction And Translation Adjustment Net Of Tax

us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax

us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax


Other
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-30
Value138.3014.435-8.1176.704-8.4232.878-3.098-6.993-0.134-12.4654.8651.0788.557102.592-10.2612.796-4.4326.943-9.076-1.452-0.694-3.852-3.307-3.1690.188-1.801-0.430.367-2.0850.323-0.2811.96-0.781.39-0.086-2.5480.733
Percentage of OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.71.91.5-3.83.0-3.71.3-1.4-3.2-0.1-4.72.30.73.53.61.1-3.01.1-1.72.7-4.1-1.4-36.4-186.2-160.5-127.78.7-91.4-16.513.2-65.410.4-19.81960.00.00.00.00.00.0

Other Nonoperating Income Expense

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:OtherNonoperatingIncomeExpense


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value-11.783-0.9272.0644.74918-12.3329.086-15.47-5.8740.977-8.118-0.8248.5841.8937.3520.597-0.5333.0420.36-2.9725.970.546-9.004170.76-1.508-5.132-2.7642.991.81722-7.7878.0272.331-0.371-0.12-0.4270.974-0.287-0.671-0.1390.0430.203-0.32-0.39
Percentage of OtherNonoperatingIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2.7-0.20.41.16.0-5.84.1-6.8-2.60.4-3.7-0.33.30.94.60.2-0.21.30.1-1.12.20.2-4.116.839.8-72.9-249.1-111.4138.992.2872.6-281.1251.875.4-26.2-120.00.00.00.00.00.00.00.00.00.0

Profit Loss

us-gaap:ProfitLoss

us-gaap:ProfitLoss


Profit
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-31
Value2333-59.132-62.007-59.806-80.762-76.07-27.655-6.201-43.114-213.905-46.442-17.528-30.995-13.661-14.97715-11.9781.603128-43.241-118.037-53.461-50.014-26.075-45.091-17.429-60.801-4.353-34.762-1.04-9.646-10.245-8.611
Percentage of ProfitLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.511.2-28.0-27.1-26.4-36.3-34.3-11.1-2.4-20.4-132.9-18.9-6.0-13.6-4.0-5.85.8-4.70.7123.4-2266.3-5705.0-2595.2-2015.1-1211.1-2288.9-668.3-2195.0-136.5-1124.3-73.4-9646.00.00.0

us-gaap:ProfitLoss us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees


Profit
Period End2021-06-302021-03-312020-12-312020-09-30
Value4.2-10.1-24.2-24.6
Percentage of ProfitLoss0.00.00.0-103.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.9-1.9-4.9-5.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees0.00.00.00.0

Research And Development Expense

us-gaap:ResearchAndDevelopmentExpense

us-gaap:ResearchAndDevelopmentExpense


Research
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value18191718172123302836333029323432322627243127251829252520162023119.5579.916.5783.6214.494.8314.2553.3013.1541.0882.3151.5431.575
Percentage of ResearchAndDevelopmentExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax4.13.53.54.35.810.310.313.112.516.415.012.111.115.621.313.111.111.48.19.411.811.011.518.21549.81232.61253.7826.6754.01065.7895.3400.2299.8320.5464.23621.00.00.00.00.00.00.00.00.00.0

Revenue From Contract With Customer Excluding Assessed Tax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value4425454944283012112242282262222212492632111602462922283392592662522211031.9082.0692.062.4822.1531.972.6082.773.1883.0921.4170.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ConsolidationItems, us-gaap:ProductOrService, us-gaap:StatementBusinessSegments

us-gaap:OperatingSegments, opk:TransferOfIntellectualPropertyAndOther, opk:Diagnostics


Revenue
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value0.0106.1940.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.02.32.10.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.02.32.10.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments opk:TransferOfIntellectualPropertyAndOther opk:Diagnostics0.0100.0100.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:OperatingSegments, opk:TransferOfIntellectualPropertyAndOther, opk:Pharmaceutical


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value9.5484.2695.9226.819149.55314211918132119157.842229
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.20.81.21.64.94.56.49.48.58.26.18.77.27.54.99.110.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.20.81.21.64.94.56.49.48.58.26.18.77.27.54.99.110.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments opk:TransferOfIntellectualPropertyAndOther opk:Pharmaceutical100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingSegments, us-gaap:Product, opk:Pharmaceutical


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value3533302829313226282525252827332228
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax8.16.26.26.79.714.714.311.412.711.411.410.210.813.221.09.39.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax8.16.26.26.79.714.714.311.412.711.411.410.210.813.221.09.39.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments us-gaap:Product opk:Pharmaceutical100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingSegments, us-gaap:Service, opk:Diagnostics


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value397506457382250170177181178178183202216211119200233
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax89.893.092.689.483.380.879.379.278.880.482.581.281.9100.074.281.679.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax89.893.092.689.483.380.879.379.278.880.482.581.281.9100.074.281.679.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:OperatingSegments us-gaap:Service opk:Diagnostics100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement

opk:BioReference, opk:TransferOfIntellectualPropertyAndOther, us-gaap:Product


Revenue
Period End2020-12-312020-09-302020-06-30
Value0.010.06.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.02.32.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.02.32.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:BioReference opk:TransferOfIntellectualPropertyAndOther us-gaap:Product0.0100.0100.0

opk:Nicoya, opk:TransferOfIntellectualPropertyAndOther, us-gaap:Product


Revenue
Period End2021-06-30
Value5.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:Nicoya opk:TransferOfIntellectualPropertyAndOther us-gaap:Product100.0

opk:Pfizer, opk:TransferOfIntellectualPropertyAndOther, us-gaap:Product


Revenue
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-30
Value2.82.83.1138.71918171816
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.60.50.74.64.18.58.07.87.66.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.60.50.74.64.18.58.07.87.66.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:Pfizer opk:TransferOfIntellectualPropertyAndOther us-gaap:Product100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService

opk:ClientPayers


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value22526224920714139394338383437453722344233
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax51.148.250.548.646.818.517.719.116.817.315.415.117.417.813.914.114.714.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax51.148.250.548.646.818.517.719.116.817.315.415.117.417.813.914.114.714.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:ClientPayers100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:GovernmentPayers


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value577325211526292828296267726738678077
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax13.013.55.25.05.312.713.112.312.613.328.127.227.531.823.627.427.433.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax13.013.55.25.05.312.713.112.312.613.328.127.227.531.823.627.427.433.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:GovernmentPayers100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:HealthInsurers


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value10916416313684991031041061058292921005592104112
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax24.730.233.131.927.946.946.345.546.947.637.036.934.947.834.537.835.749.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax24.730.233.131.927.946.946.345.546.947.637.036.934.947.834.537.835.749.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:HealthInsurers100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:Patients


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value4.5665.55718169.9135.6964.995.1635.4455.0814.6335.0675.7355.6973.4455.8276.5484.857
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.01.03.73.93.32.72.22.32.42.32.12.02.22.72.12.42.22.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.01.03.73.93.32.72.22.32.42.32.12.02.22.72.12.42.22.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:Patients100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:Rayaldee


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value161520222222261914121210
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.62.94.25.17.610.711.98.66.65.75.74.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.62.94.25.17.610.711.98.66.65.75.74.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:Rayaldee100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:TransferOfIntellectualPropertyAndOther


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value9.5484.2695.92216209.55314211918132119157.842229
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.20.81.23.96.94.56.49.48.58.26.18.77.27.54.99.110.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.20.81.23.96.94.56.49.48.58.26.18.77.27.54.99.110.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:TransferOfIntellectualPropertyAndOther100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Product


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value3533302829313226282525252827332228
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax8.16.26.26.79.714.714.311.412.711.411.410.210.813.221.09.39.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax8.16.26.26.79.714.714.311.412.711.411.410.210.813.221.09.39.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Service


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value397506457382250170177181178178183202216211119200233
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax89.893.092.689.483.380.879.379.278.880.482.581.281.9100.074.281.679.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax89.893.092.689.483.380.879.379.278.880.482.581.281.9100.074.281.679.9
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Service100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService, us-gaap:DebtInstrument

opk:TransferOfIntellectualPropertyAndOther, opk:DistributionToHealthcareProvidersCOVID19


Revenue
Period End2021-03-312020-12-312020-09-302020-06-30
Value160.010.06.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.00.02.32.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.00.02.32.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:TransferOfIntellectualPropertyAndOther opk:DistributionToHealthcareProvidersCOVID19100.00.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:StatementGeographical

country:CL


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-30
Value1814111111108.298.4369.0517.8658.628.9261111101111108.8489.9369.5976.9836.9567.7798.6986.4526.3967.6227.8527.2857.4347.9938.4827.7416.8456.7817.1875.7013.9215.35612
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax4.22.62.22.63.75.13.73.74.03.53.93.64.55.66.74.74.14.42.63.83.62.83.17.5455.9311.8310.5307.1364.7369.8285.0288.6266.1250.4483.16781.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax4.22.62.22.63.75.13.73.74.03.53.93.64.55.66.74.74.14.42.63.83.62.83.17.5455.9311.8310.5307.1364.7369.8285.0288.6266.1250.4483.16781.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax country:CL100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

country:ES


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-30
Value5.4375.9194.9273.7134.1364.1565.2814.1724.8764.4183.9264.1444.5925.5324.5394.1235.1184.5053.5553.914.3244.0234.3193.4474.923.9375.0934.4145.6666.155.2974.0265.1534.3244.1271.9970.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.21.11.00.91.42.02.41.82.22.01.81.71.72.62.81.71.72.01.01.51.61.61.93.3257.9190.3247.2177.8263.2312.2203.1145.3161.6139.8291.21997.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1.21.11.00.91.42.02.41.82.22.01.81.71.72.62.81.71.72.01.01.51.61.61.93.3257.9190.3247.2177.8263.2312.2203.1145.3161.6139.8291.21997.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax country:ES100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

country:IE


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-31
Value127.1296.1848.9881611152222201524201714252220-0.017207122252219120.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.71.31.32.15.65.66.910.09.89.27.09.87.98.28.810.57.79.1-0.08.027.08.811.421.51015.5585.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2.71.31.32.15.65.66.910.09.89.27.09.87.98.28.810.57.79.1-0.08.027.08.811.421.51015.5585.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax country:IE100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.00.00.0

country:IL


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-31
Value0.7242.5120.2411.1191.1831.707-0.0531.9383.7683.1161.0552.2832.5263.6140.1441.9357.6544.2172.4553.6994.424.7433.7984.1545.9424.2136.0753.716.3074.5463.5863.0993.9952.5722.9941.5161.5181.627
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.20.50.00.30.40.8-0.00.81.71.40.50.91.01.70.10.82.61.80.71.41.71.91.74.0311.4203.6294.9149.5292.9230.8137.5111.9125.383.2211.31516.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.20.50.00.30.40.8-0.00.81.71.40.50.91.01.70.10.82.61.80.71.41.71.91.74.0311.4203.6294.9149.5292.9230.8137.5111.9125.383.2211.31516.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax country:IL100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

country:MX


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-30
Value3.0392.4181.8782.281.8661.8412.8011.6422.0581.5311.4931.3821.3021.421.5331.4830.7240.8650.680.6750.9260.7060.8310.9880.9680.8850.9021.5281.5461.8311.1361.4450.9880.891.2781.2011.2121.3111.811.4043.164
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.70.40.40.50.60.91.20.70.90.70.70.60.50.71.00.60.20.40.20.30.30.30.41.050.742.843.861.671.892.943.652.231.028.890.21201.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.70.40.40.50.60.91.20.70.90.70.70.60.50.71.00.60.20.40.20.30.30.30.41.050.742.843.861.671.892.943.652.231.028.890.21201.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax country:MX100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

country:US


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-31
Value4025124704002651801921891841841912082222151292012442551552592662522351042.5252.4937.062.4822.1532.4463.2394.0785.203151.0170.30.2940.138
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax90.994.195.193.688.385.585.882.881.483.186.183.584.4101.980.681.783.6111.945.8100.1100.0100.0106.0100.4132.3120.5342.7100.0100.0124.2124.2147.2163.2512.671.8300.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax90.994.195.193.688.385.585.882.881.483.186.183.584.4101.980.681.783.6111.945.8100.1100.0100.0106.0100.4132.3120.5342.7100.0100.0124.2124.2147.2163.2512.671.8300.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax country:US100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:OtherCountries


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-31
Value0.1720.1640.1280.1240.1330.1390.1180.1310.1310.0930.1090.0270.0150.0220.0210.040.0310.030.0060.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.00.00.00.00.00.10.10.10.10.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.00.00.00.00.00.10.10.10.10.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax opk:OtherCountries100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.00.0

Selling General And Administrative Expense

us-gaap:SellingGeneralAndAdministrativeExpense

us-gaap:SellingGeneralAndAdministrativeExpense


Selling
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value11311210199777679808895958487911241311281361201241171281025520171514141315131312107.3225.4354.6715.0674.3484.9195.0555.3314.445.644
Percentage of SellingGeneralAndAdministrativeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax25.620.620.623.325.836.035.335.239.142.842.933.733.243.377.453.443.959.835.548.244.250.746.453.21097.3843.2740.0564.5690.8701.1592.2490.0435.4401.8731.67322.00.00.00.00.00.00.00.00.00.0

Assets

us-gaap:Assets

us-gaap:Assets


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value2421251924732371232322322309236924562575245124802530257825842721276827602766280027742793279930151525151212671295132713551391138264165328925023023122915116077
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Assets us-gaap:ConsolidationItems

us-gaap:CorporateNonSegment


Assetsus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value36372844544899197817852475558607293127636882111614651303089512515617420918035
Percentage of Assets1.51.51.11.92.32.24.30.83.26.92.11.92.22.32.32.73.44.62.32.53.04.02.215.48.620.47.59.711.812.915.113.112.1
Percentage of Assets1.51.51.11.92.32.24.30.83.26.92.11.92.22.32.32.73.44.62.32.53.04.02.215.48.620.47.59.711.812.915.113.112.1
Percentage of Assets us-gaap:CorporateNonSegment100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Assets us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:OperatingSegments, opk:Diagnostics


Assetsus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value122713301268117611211026103511141138116511621176121712261241133913801345140814121408143514791287104105108109110113116114112
Percentage of Assets50.752.851.349.648.346.044.847.046.445.347.447.448.147.548.049.249.948.850.950.550.851.452.942.76.87.08.58.48.38.48.48.338.8
Percentage of Assets50.752.851.349.648.346.044.847.046.445.347.447.448.147.548.049.249.948.850.950.550.851.452.942.76.87.08.58.48.38.48.48.338.8
Percentage of Assets us-gaap:OperatingSegments opk:Diagnostics100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingSegments, opk:Pharmaceutical


Assetsus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value11581151117611511148115711741235123912301236125712581294128213091294128612941318128312461258126212901098106410611059106710651087142
Percentage of Assets47.845.747.648.549.451.850.952.150.547.850.450.749.750.249.648.146.846.646.847.146.344.644.941.984.672.684.081.979.878.876.578.749.1
Percentage of Assets47.845.747.648.549.451.850.952.150.547.850.450.749.750.249.648.146.846.646.847.146.344.644.941.984.672.684.081.979.878.876.578.749.1
Percentage of Assets us-gaap:OperatingSegments opk:Pharmaceutical100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Assets us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees


Assetsus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value179109908979191
Percentage of Assets7.44.33.73.83.48.3
Percentage of Assets7.44.33.73.83.48.3
Percentage of Assets us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees100.0100.0100.0100.0100.0100.0

Liabilities

us-gaap:Liabilities

us-gaap:Liabilities


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value67982380174773568369472774781265969272075569963266165367469475879581910466986994314074145245185153283348679545244222328
Percentage of Liabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets28.032.732.431.531.630.630.130.730.431.626.927.928.529.327.123.323.923.724.424.827.328.529.334.745.846.334.131.531.238.737.337.251.351.129.931.723.722.519.314.814.436.8

us-gaap:Liabilities us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees


Liabilitiesus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value262328373258
Percentage of Liabilities3.92.93.54.94.48.4
Percentage of Assets1.10.91.11.61.42.5
Percentage of Assets us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees14.921.831.241.540.730.5

Liabilities And Stockholders Equity

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:LiabilitiesAndStockholdersEquity


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value2421251924732371232322322309236924562575245124802530257825842721276827602766280027742793279930151525151212671295132713551391138264165328925023023122915116077
Percentage of LiabilitiesAndStockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-312009-12-312008-12-31
Value167116141791184320461979197083481984289391783587687031432017914615115416010211123310.359
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets67.669.973.171.374.070.765.354.754.266.469.069.161.663.063.049.149.161.958.565.766.970.167.969.329.60.00.0

us-gaap:StockholdersEquity us-gaap:BusinessAcquisition

opk:BioReference


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312015-12-31
Value1095107710009688851000
Percentage of StockholdersEquity0.00.059.80.054.850.5
Percentage of Assets45.242.740.440.838.335.7
Percentage of Assets opk:BioReference0.00.00.00.00.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-31
Value-4.225-22.07-20.131-0.528-27.009
Percentage of StockholdersEquity-0.3-1.4-1.1-0.0-1.3
Percentage of Assets-0.2-1.0-0.8-0.0-1.0
Percentage of Assets us-gaap:AccumulatedOtherComprehensiveIncome0.00.00.00.00.0

us-gaap:AccumulatedTranslationAdjustment


Stockholders
Period End2021-06-302021-03-312020-12-312019-12-312018-12-312017-12-31
Value-9.932-13.295-4.225-22.07-20.131-5.404
Percentage of StockholdersEquity0.00.0-0.3-1.4-1.1-0.3
Percentage of Assets-0.4-0.5-0.2-1.0-0.8-0.2
Percentage of Assets us-gaap:AccumulatedTranslationAdjustment0.00.00.00.00.00.0

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value31523142300428892845565524376367307
Percentage of StockholdersEquity188.6194.6167.7156.7139.0315.1326.21631.11161.585654.0
Percentage of Assets127.5136.1122.6111.8102.8195.0228.7483.00.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value6.7066.7045.8695.65.5863.0562.9752.5542.5381.991
Percentage of StockholdersEquity0.40.40.30.30.31.71.811.18.0554.6
Percentage of Assets0.30.30.20.20.21.11.33.30.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value-1481.833-1511.077-1197.078-1048.914-775.329-388.77-359.722-358.379-339.229-309.116
Percentage of StockholdersEquity-88.7-93.6-66.8-56.9-37.9-216.7-223.6-1554.7-1073.5-86104.7
Percentage of Assets-59.9-65.4-48.8-40.6-28.0-134.1-156.7-460.40.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.0

us-gaap:TreasuryStock


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value-1.791-1.791-1.791-1.791-1.911-7.457-8.092-0.061-0.061-0.024
Percentage of StockholdersEquity-0.1-0.1-0.1-0.1-0.1-4.2-5.0-0.3-0.2-6.7
Percentage of Assets-0.1-0.1-0.1-0.1-0.1-2.6-3.5-0.10.00.0
Percentage of Assets us-gaap:TreasuryStock0.00.00.00.00.00.00.00.00.00.0

Assets Current

us-gaap:AssetsCurrent

us-gaap:AssetsCurrent


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value547599523428360274324292344435317289321349343430472459483502505453454517278394142163183205242241230237788792999911712754
Percentage of AssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets22.623.821.218.115.512.314.012.414.016.913.011.712.713.513.315.817.116.717.517.918.216.216.217.218.226.111.312.613.815.117.417.435.936.327.135.240.142.943.477.979.669.5

Cash And Cash Equivalents At Carrying Value

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashAndCashEquivalentsAtCarryingValue


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-302009-12-312008-12-31
Value6589723621348564111207964380999110013013116814415617419321222134896118134156185155119181272338477147384718159.686426.678
Percentage of CashAndCashEquivalentsAtCarryingValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.73.62.91.50.91.53.72.74.58.03.91.83.23.93.53.74.74.76.15.25.66.36.97.014.523.07.69.110.111.513.411.318.627.89.49.416.620.331.231.324.20.023.10.00.00.00.0

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value65897236213485641112079643809991168
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.73.62.91.50.91.53.72.74.58.03.91.83.23.93.56.1

Accounts Receivable Net Current

us-gaap:AccountsReceivableNetCurrent

us-gaap:AccountsReceivableNetCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value265320286241214132134140148144143157152158165233251238220223213204193189261919212319192122212119151612121513
Percentage of AccountsReceivableNetCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets11.012.711.610.29.25.95.85.96.05.65.96.36.06.26.48.69.18.78.08.07.77.36.96.31.81.31.61.61.71.51.41.53.53.27.37.76.97.05.58.49.717.1

Inventory Net

us-gaap:InventoryNet

us-gaap:InventoryNet


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value1341591321117258535048444243464949464847474342403940201816161818181919232221171813101619
Percentage of InventoryNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets5.66.35.44.73.12.62.32.12.01.71.71.71.81.91.91.71.71.71.71.51.51.51.41.31.31.21.31.31.41.41.31.43.13.57.78.67.47.95.87.010.225.6

Inventory Finished Goods

us-gaap:InventoryFinishedGoods

us-gaap:InventoryFinishedGoods


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value3839363024232522211815141622212221191614131413131314121112121314151917171411
Percentage of InventoryFinishedGoods100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.61.61.51.31.01.11.10.90.90.70.60.60.70.90.80.80.80.70.60.50.50.50.50.50.90.91.00.90.91.01.01.12.42.96.27.16.44.8

Other Assets Current

us-gaap:OtherAssetsCurrent

us-gaap:OtherAssetsCurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value155.0635.3097.5421915153.3273.2344.5113.8474.2434.7644.373.8383.883.2873.8487.5080.8740.7760.3060.9032.3573.3883.3844.2122.5912.6135.6555.6534.3044.75
Percentage of OtherAssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.70.20.20.30.80.70.70.10.10.20.20.20.20.20.10.10.10.10.30.00.00.00.00.10.20.20.30.20.20.40.40.31.6

Prepaid Expense And Other Assets Current

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent


Prepaid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value4729323851485037363835454140374941424790783326749.6238.4459.3897.0187.55310191919117.8735.0044.072.6542.1791.7291.9272.782
Percentage of PrepaidExpenseAndOtherAssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.01.21.31.62.22.22.21.61.51.51.41.81.61.61.41.81.51.51.73.22.81.21.02.50.60.60.70.50.60.81.41.43.01.82.72.01.81.10.91.11.23.6

Amortization Of Intangible Assets

us-gaap:AmortizationOfIntangibleAssets

us-gaap:AmortizationOfIntangibleAssets


Amortization
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value12121213141415161616161617173018171717181513138.113.2362.6652.6152.7352.8262.7442.9412.792.6882.7142.0232.178
Percentage of AmortizationOfIntangibleAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Property Plant And Equipment Net

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:PropertyPlantAndEquipmentNet


Property
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value1391401341301271271281371391441471501481461421331261221251281331311262315161717161717161616125.2325.3435.3583.2713.0932.729
Percentage of PropertyPlantAndEquipmentNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets5.55.75.75.65.75.55.45.65.45.95.95.95.85.75.24.84.64.44.54.64.84.74.21.51.01.31.31.31.21.21.22.62.65.75.12.32.32.32.21.93.5

Long Term Investments

us-gaap:LongTermInvestments

us-gaap:LongTermInvestments


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value8.945101514261020112432314245414032343741383435343421222226333530242628151414106.7175.8624.245.114
Percentage of LongTermInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.40.40.60.61.10.50.90.51.01.31.31.71.81.61.61.21.21.41.51.41.21.31.21.21.41.51.82.12.52.62.21.84.24.45.46.06.44.42.93.92.66.6

Goodwill

us-gaap:Goodwill

us-gaap:Goodwill


Goodwill
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value677676680675671669671695699698700713714719717715712705704700691746743761289223224224226226226222828280494040396.2346.8535.856
Percentage of Goodwill100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets28.026.827.528.528.930.029.129.428.527.128.628.828.227.927.726.325.725.625.525.024.926.726.625.219.014.817.717.417.016.716.316.112.812.627.819.917.817.417.34.14.37.5

us-gaap:Goodwill us-gaap:BusinessAcquisition

opk:BioReference


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-08-312015-08-20
Value434434434434434434434401401401401401401401401401401401401392386440441441472
Percentage of Goodwill64.264.363.964.364.764.964.757.757.457.557.456.356.355.856.056.256.456.957.056.056.059.059.30.00.0
Percentage of Assets18.017.317.618.318.719.518.817.016.415.616.416.215.915.615.514.814.514.614.514.013.915.815.80.00.0
Percentage of Assets opk:BioReference0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:Goodwill us-gaap:BusinessAcquisition, us-gaap:StatementBusinessSegments

opk:BioReference, opk:Diagnostics


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302014-12-312013-12-31
Value4344344344344344344344014014014014014014014014014014014013913864404414720.00.0
Percentage of Goodwill64.264.363.964.364.764.964.757.757.457.557.456.356.355.856.056.256.456.957.056.056.059.059.362.10.00.0
Percentage of Assets18.017.317.618.318.719.518.817.016.415.616.416.215.915.615.514.814.514.614.514.013.915.815.815.70.00.0
Percentage of Assets opk:BioReference opk:Diagnostics0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:CURNA, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-01-012020-01-012019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value4.8274.8270.04.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.8274.827
Percentage of Goodwill0.00.00.00.70.70.70.70.70.70.70.70.70.70.70.70.70.70.60.60.61.72.22.22.12.12.12.16.012.1
Percentage of Assets0.00.00.00.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.30.30.40.40.40.40.31.72.1
Percentage of Assets opk:CURNA opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:EirGenPharmaLimited, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302014-12-312013-12-31
Value908993898584858184838586879189878579788382848167660.00.0
Percentage of Goodwill13.413.213.713.212.812.512.711.712.112.012.212.112.212.812.412.311.911.311.111.912.011.310.98.822.90.00.0
Percentage of Assets3.73.53.83.83.73.83.73.43.43.23.53.53.43.63.53.23.12.92.83.03.03.02.92.24.30.00.0
Percentage of Assets opk:EirGenPharmaLimited opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:FineTech, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-01-012020-01-012019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value11110.00.00.00.00.011111111111111111111111111111111111111111111
Percentage of Goodwill0.00.00.00.00.00.00.01.61.61.61.61.61.61.71.71.71.71.61.61.54.05.25.25.25.25.25.214.529.2
Percentage of Assets0.00.00.00.00.00.00.00.50.50.50.50.40.40.40.40.40.40.40.40.40.80.80.90.90.90.90.84.05.1
Percentage of Assets opk:FineTech opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:OPKOHealthEurope, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302013-12-312012-12-31
Value7.8327.7328.0867.737.4037.2527.3947.1987.4967.3967.5467.6517.7018.1257.8987.7897.5317.0436.9367.3927.3217.4877.1917.4137.3147.1548.0138.3639.0758.712
Percentage of Goodwill1.21.11.21.11.11.11.11.01.11.11.11.11.11.11.11.11.11.01.01.11.11.01.01.02.53.23.63.74.010.8
Percentage of Assets0.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.30.20.50.50.60.60.73.0
Percentage of Assets opk:OPKOHealthEurope opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:OPKOMexico, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-01-012020-01-012019-01-012015-09-302015-06-302015-03-312014-12-312014-09-302013-12-31
Value0.10.10.10.0870.0950.0970.10.110.113
Percentage of Goodwill0.00.00.00.00.00.00.00.00.0
Percentage of Assets0.00.00.00.00.00.00.00.00.0
Percentage of Assets opk:OPKOMexico opk:Pharmaceutical0.00.00.00.00.00.00.00.00.0

opk:OpkoChile, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-31
Value4.3924.4174.5054.0763.8983.7344.3484.4024.7264.7054.6144.8674.8965.3015.2035.0024.8174.8314.7854.864.8264.7124.5174.5445.045.1085.2835.3185.7925.8086.1026.697
Percentage of Goodwill0.60.70.70.60.60.60.60.60.70.70.70.70.70.70.70.70.70.70.70.70.70.60.60.61.72.32.42.42.62.62.78.3
Percentage of Assets0.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.30.30.40.40.40.40.42.3
Percentage of Assets opk:OpkoChile opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:OpkoDiagnostics, opk:Diagnostics


Goodwillus-gaap:
Period End2021-01-012020-01-012019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value17170.0171717173232321732323217323232173232323232323232290.0
Percentage of Goodwill0.00.00.02.62.62.62.64.64.64.62.54.64.64.72.64.74.84.42.44.311.414.814.714.714.614.614.636.80.0
Percentage of Assets0.00.00.00.80.70.70.71.31.31.30.71.21.21.20.61.21.21.20.61.12.22.22.62.52.52.42.410.20.0
Percentage of Assets opk:OpkoDiagnostics opk:Diagnostics0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:PROLOR, opk:Pharmaceutical


Goodwillus-gaap:
Period End2020-12-312020-01-012019-12-312019-01-012018-12-312017-12-312016-12-312015-12-312014-12-312014-06-302014-03-312013-12-312012-12-312011-12-31
Value1391391391391391391391391391391391390.00.0
Percentage of Goodwill20.50.020.80.020.019.519.818.862.361.961.861.70.00.0
Percentage of Assets5.70.06.10.05.75.45.15.011.010.510.310.00.00.0
Percentage of Assets opk:PROLOR opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.0

opk:TransitionTherapeuticsInc., opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-01-012020-01-012019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-312014-12-31
Value3.4213.4210.03.423.463.3933.3223.513.4483.5113.6083.6213.483.3883.363.4370.00.0
Percentage of Goodwill0.00.00.00.50.50.50.50.50.50.50.50.50.50.50.50.50.00.0
Percentage of Assets0.00.00.00.10.10.10.10.10.10.10.10.10.10.10.10.10.00.0
Percentage of Assets opk:TransitionTherapeuticsInc. opk:Pharmaceutical0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:Goodwill us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:OperatingSegments, opk:Diagnostics


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value434434434434434434434452452452452452452452452452452452452442437491492523505050505050504747
Percentage of Goodwill64.264.363.964.364.764.964.765.164.764.864.763.463.462.963.163.363.664.164.363.263.465.866.268.817.622.822.722.722.622.522.521.459.2
Percentage of Assets18.017.317.618.318.719.518.819.118.417.618.518.317.917.617.516.616.416.416.415.815.817.617.617.43.33.44.03.93.83.83.73.416.4
Percentage of Assets us-gaap:OperatingSegments opk:Diagnostics35.432.734.337.038.842.342.040.639.838.839.038.537.236.936.533.832.833.632.131.431.134.333.340.748.848.247.246.746.144.943.641.642.3

us-gaap:OperatingSegments, opk:Pharmaceutical


Goodwillus-gaap:
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value24224124524023623423724324724524726026126726426225925325125725325525123723817217317317517517517432
Percentage of Goodwill35.835.736.135.735.335.135.334.935.335.235.336.636.637.136.936.736.435.935.736.836.634.233.831.282.477.277.377.377.477.577.578.640.8
Percentage of Assets10.09.69.910.210.210.510.310.310.19.510.110.510.310.410.29.79.49.29.19.29.19.19.07.915.611.413.713.413.212.912.612.611.3
Percentage of Assets us-gaap:OperatingSegments opk:Pharmaceutical20.921.020.920.920.620.320.219.719.920.020.020.820.820.620.620.120.019.719.419.519.720.520.018.818.515.716.316.416.516.416.516.123.1

Indefinite Lived Intangible Assets Excluding Goodwill

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill


Indefinite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value100010001100110011001100110063563563563564664564664764864564564464660679379281281279379379379379379379311
Percentage of IndefiniteLivedIntangibleAssetsExcludingGoodwill100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets41.339.744.546.447.349.347.626.825.924.725.926.125.525.125.023.823.323.423.323.121.828.428.326.953.352.462.661.259.858.557.057.44.0

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill us-gaap:IndefiniteLivedIntangibleAssetsByMajorClass

us-gaap:InProcessResearchAndDevelopment


Indefinite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-12-31
Value590590590590590590590635
Percentage of IndefiniteLivedIntangibleAssetsExcludingGoodwill59.059.053.753.753.753.753.7100.0
Percentage of Assets24.423.423.924.925.426.425.625.9
Percentage of Assets us-gaap:InProcessResearchAndDevelopment0.00.00.00.00.00.00.00.0

Finite Lived Intangible Assets Net

us-gaap:FiniteLivedIntangibleAssetsNet

us-gaap:FiniteLivedIntangibleAssetsNet


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value44545647548649951352856458159761463164866768371473174676378180462563866094596265697174777982958275757614189.964
Percentage of FiniteLivedIntangibleAssetsNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets18.418.119.220.521.523.022.923.823.723.225.125.525.625.926.526.326.427.127.627.929.022.422.821.96.23.94.95.15.25.35.45.612.412.633.033.032.932.433.49.411.612.8

Operating Lease Right Of Use Asset

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:OperatingLeaseRightOfUseAsset


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value36383736383939352933
Percentage of OperatingLeaseRightOfUseAsset100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.51.51.51.51.71.81.71.51.21.3

Other Assets Noncurrent

us-gaap:OtherAssetsNoncurrent

us-gaap:OtherAssetsNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value9.69.745105.8577.4877.0266.8885.5283.773.1267.2229.6525.2465.6275.6153839385.7564.3054.3854.5225.2671026.0135.0735.8384.6734.916.526.8617.0032.7842.8632.7771.871.2441.2671.2870.8240.060.111
Percentage of OtherAssetsNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.40.40.40.20.30.30.30.20.20.10.30.40.20.20.21.41.41.40.20.20.20.20.23.40.40.30.50.40.40.50.50.50.40.41.00.70.50.50.60.50.00.1

Equity Securities Fv Ni

us-gaap:EquitySecuritiesFvNi

us-gaap:EquitySecuritiesFvNi


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value7.4668.8371412248.99189.1292027262222
Percentage of EquitySecuritiesFvNi100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.30.40.60.51.10.40.80.40.81.11.10.90.9

us-gaap:EquitySecuritiesFvNi us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel1


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value7.4668.8371412248.99189.129202726
Percentage of EquitySecuritiesFvNi100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.30.40.60.51.10.40.80.40.81.11.1
Percentage of Assets us-gaap:FairValueInputsLevel10.00.00.00.00.00.00.00.00.00.00.0

Accounts Payable Current

us-gaap:AccountsPayableCurrent

us-gaap:AccountsPayableCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value8816210065445562776051476569647466627453586173727716108.7448.841101413131111107.2384.4024.8774.8912.5562.897.17
Percentage of AccountsPayableCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets3.76.54.12.81.92.52.73.32.52.01.92.62.72.52.92.42.22.71.92.12.22.62.62.61.10.70.70.70.81.11.01.01.81.73.52.91.92.12.11.71.89.2

Accrued Liabilities Current

us-gaap:AccruedLiabilitiesCurrent

us-gaap:AccruedLiabilitiesCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value1872132402482101641641721982172032142002172151762061781971862091821672011491586055545865433126242112104.9563.6784.0335.739
Percentage of AccruedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets7.78.59.710.59.07.47.17.38.18.48.38.77.98.48.36.57.56.57.26.67.66.56.06.79.810.54.84.34.14.34.73.14.84.18.58.75.54.52.22.42.57.4

Contract With Customer Liability Current

us-gaap:ContractWithCustomerLiabilityCurrent

us-gaap:ContractWithCustomerLiabilityCurrent


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value8.41515141610193050656361616161
Percentage of ContractWithCustomerLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.30.60.60.60.70.50.81.32.12.52.62.52.42.42.4

Liabilities Current

us-gaap:LiabilitiesCurrent

us-gaap:LiabilitiesCurrent


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value30340337533527924524927028339628831730631830125828326426325428126725135718018283767984917159585246312918202127
Percentage of LiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets12.616.015.214.212.011.010.811.411.515.411.812.812.112.311.79.510.29.69.59.110.19.69.011.911.812.16.65.96.06.26.65.29.38.918.118.613.812.88.213.413.435.5

Long Term Debt Current

us-gaap:LongTermDebtCurrent us-gaap:LongtermDebtType

us-gaap:LongTermDebtCurrent

opk:NotesPayableAndOtherLongTermLiabilities


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value1.7641.7241.7491.9142.4151.9272.4941.9032.6492.522.56
Percentage of LongTermDebtCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.10.10.10.10.10.10.10.10.10.10.1
Percentage of Assets opk:NotesPayableAndOtherLongTermLiabilities0.00.00.00.00.00.00.00.00.00.00.0

us-gaap:NotesPayableOtherPayables


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value1.7641.7241.7492.292
Percentage of LongTermDebtCurrent100.0100.0100.091.9
Percentage of Assets0.10.10.10.1
Percentage of Assets us-gaap:NotesPayableOtherPayables0.00.00.00.0

Operating Lease Liability Current

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OperatingLeaseLiabilityCurrent


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value10109.0289.08101112121315
Percentage of OperatingLeaseLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.40.40.40.40.40.50.50.50.50.6

Other Accrued Liabilities Current

us-gaap:OtherAccruedLiabilitiesCurrent

us-gaap:OtherAccruedLiabilitiesCurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value696978735668588481806277657579475038583736232319151014121412155.8876.182
Percentage of OtherAccruedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.92.83.23.12.43.12.53.63.33.12.53.12.62.93.11.71.81.42.11.31.30.80.80.71.00.71.21.01.10.91.10.42.1

Liabilities Noncurrent

us-gaap:LiabilitiesNoncurrent

us-gaap:LiabilitiesNoncurrent


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312011-09-302011-06-302010-12-31
Value375419426411455438445457463416371374413437397374378388411440477528567688518516348331334439426443269275342.1541.61.067
Percentage of LiabilitiesNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets15.516.617.217.419.619.719.319.318.916.215.215.116.317.015.413.713.714.114.915.717.218.920.322.834.034.227.525.625.232.530.732.142.042.211.81.41.01.4

Long Term Debt

us-gaap:LongTermDebt

us-gaap:LongTermDebt


Long
Period End2021-06-302021-03-312020-12-312019-12-312012-09-30
Value2052462512703.954
Percentage of LongTermDebt100.0100.0100.0100.0100.0
Percentage of Assets8.59.810.211.71.6

us-gaap:LongTermDebt us-gaap:BalanceSheetLocation

opk:ConvertibleNotes


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value183224221211
Percentage of LongTermDebt89.191.288.478.1
Percentage of Assets7.68.99.09.1
Percentage of Assets opk:ConvertibleNotes0.00.00.00.0

opk:LineOfCreditAndNotesAndLoansPayableCurrent


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value1717249.619
Percentage of LongTermDebt8.77.29.83.6
Percentage of Assets0.70.71.00.4
Percentage of Assets opk:LineOfCreditAndNotesAndLoansPayableCurrent0.00.00.00.0

us-gaap:OtherNoncurrentLiabilities


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value4.5173.9194.51349
Percentage of LongTermDebt2.21.61.818.3
Percentage of Assets0.20.20.22.1
Percentage of Assets us-gaap:OtherNoncurrentLiabilities0.00.00.00.0

us-gaap:LongTermDebt us-gaap:CreditFacility, us-gaap:DebtInstrument, us-gaap:LongtermDebtType

us-gaap:RevolvingCreditFacility, opk:NewCreditAgreement, us-gaap:LineOfCredit


Long
Period End2020-12-312019-12-312019-03-31
Value7.05744105
Percentage of LongTermDebt2.816.60.0
Percentage of Assets0.31.94.1
Percentage of Assets us-gaap:RevolvingCreditFacility opk:NewCreditAgreement us-gaap:LineOfCredit0.00.00.0

us-gaap:LongTermDebt us-gaap:DebtInstrument, us-gaap:LongtermDebtType

opk:A5ConvertibleNotes, us-gaap:ConvertibleDebt


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value64636260
Percentage of LongTermDebt31.225.725.022.2
Percentage of Assets2.62.52.52.6
Percentage of Assets opk:A5ConvertibleNotes us-gaap:ConvertibleDebt0.00.00.00.0

opk:ConvertibleSeniorNotesDue2025, us-gaap:ConvertibleDebt


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value116158156148
Percentage of LongTermDebt56.464.262.254.8
Percentage of Assets4.86.36.36.4
Percentage of Assets opk:ConvertibleSeniorNotesDue2025 us-gaap:ConvertibleDebt0.00.00.00.0

opk:NotesDueFebruary12033, us-gaap:ConvertibleNotesPayable


Long
Period End2021-06-302021-03-312020-12-312019-12-312019-02-012017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-01-30
Value3.053.053.053.053.031313132323232324651878787158158158175
Percentage of LongTermDebt1.51.21.21.10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets0.10.10.10.10.01.21.21.21.11.21.21.21.13.03.46.96.86.611.711.411.40.0
Percentage of Assets opk:NotesDueFebruary12033 us-gaap:ConvertibleNotesPayable0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:LongTermDebt us-gaap:LongtermDebtType

opk:NotesPayableAndOtherLongTermLiabilities


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value6.2815.6436.2626.6227.3516.2187.2176.8358.0747.8088.253
Percentage of LongTermDebt3.12.32.50.00.00.02.70.00.00.00.0
Percentage of Assets0.30.20.30.30.30.30.30.30.30.30.3
Percentage of Assets opk:NotesPayableAndOtherLongTermLiabilities0.00.00.00.00.00.00.00.00.00.00.0

us-gaap:LineOfCredit


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value1616157.327
Percentage of LongTermDebt7.96.56.32.7
Percentage of Assets0.70.60.60.3
Percentage of Assets us-gaap:LineOfCredit0.00.00.00.0

us-gaap:SeniorNotes


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312015-12-31
Value1161581561541521501481461441423130302929284348
Percentage of LongTermDebt56.464.262.20.00.00.054.80.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets4.86.36.36.56.56.76.46.25.95.51.31.21.21.21.11.11.61.7
Percentage of Assets us-gaap:SeniorNotes0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Long Term Debt Noncurrent

us-gaap:LongTermDebtNoncurrent

us-gaap:LongTermDebtNoncurrent


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value3970000.03325000.03837000.04010000.04201000.03538000.03906000.04091000.04500000.04322000.04654000.01142000.01704000.01432000.01567000.01162000.01560000.01462000.0717000.02243000.01807000.02366000.02523000.04735000.02148000.02185000.02434000.02627000.02948000.03101000.03270000.03350000.05150000.0
Percentage of LongTermDebtNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.20.10.20.20.20.20.20.20.20.20.20.00.10.10.10.00.10.10.00.10.10.10.10.20.10.10.20.20.20.20.20.21.8

us-gaap:LongTermDebtNoncurrent us-gaap:LongtermDebtType

opk:NotesPayableAndOtherLongTermLiabilities


Long
Period End2020-12-312019-12-312018-12-31
Value4513000.04723000.05693000.0
Percentage of LongTermDebtNoncurrent117.6120.9122.3
Percentage of Assets0.20.20.2
Percentage of Assets opk:NotesPayableAndOtherLongTermLiabilities0.00.00.0

us-gaap:NotesPayableOtherPayables


Long
Period End2021-06-302021-03-312020-12-312019-12-31
Value4517000.03919000.04513000.04723000.0
Percentage of LongTermDebtNoncurrent113.8117.9117.6120.9
Percentage of Assets0.20.20.20.2
Percentage of Assets us-gaap:NotesPayableOtherPayables0.00.00.00.0

Deferred Income Tax Liabilities Net

us-gaap:DeferredIncomeTaxLiabilitiesNet

us-gaap:DeferredIncomeTaxLiabilitiesNet


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312015-12-31
Value136135137119118118118113113116115134148148148118142159165226
Percentage of DeferredIncomeTaxLiabilitiesNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets5.65.45.55.05.15.35.14.84.64.54.75.45.95.85.84.45.15.86.08.1

Other Liabilities Noncurrent

us-gaap:OtherLiabilitiesNoncurrent

us-gaap:OtherLiabilitiesNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312010-12-31
Value2426374591778711112778198183209233219226201189202204224275292236408410217216218215214234807934322222251.067
Percentage of OtherLiabilitiesNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.01.11.51.93.93.53.84.75.23.08.17.48.39.18.58.37.36.97.37.38.19.910.47.826.827.117.116.716.515.915.417.012.612.211.813.29.99.711.11.4

us-gaap:OtherLiabilitiesNoncurrent us-gaap:LongtermDebtType

opk:NotesPayableAndOtherLongTermLiabilities


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value4.5173.9194.5134.7084.9364.2914.7234.9325.4255.2885.693
Percentage of OtherLiabilitiesNoncurrent18.214.712.210.55.45.55.44.44.26.82.9
Percentage of Assets0.20.20.20.20.20.20.20.20.20.20.2
Percentage of Assets opk:NotesPayableAndOtherLongTermLiabilities0.00.00.00.00.00.00.00.00.00.00.0

Operating Lease Liability Noncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value30322928282827231618
Percentage of OperatingLeaseLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.31.31.21.21.21.31.21.00.70.7

Lessee Operating Lease Liability Payments Due Year Two

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value7722000.07471000.08232000.06777000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearTwo100.0100.0100.0100.0
Percentage of Assets0.30.30.30.3

Lessee Operating Lease Liability Payments Due Year Three

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value5700000.05587000.06940000.05996000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearThree100.0100.0100.0100.0
Percentage of Assets0.20.20.30.3

Lessee Operating Lease Liability Payments Due Year Four

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value3726000.03714000.05003000.04788000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearFour100.0100.0100.0100.0
Percentage of Assets0.20.10.20.2

Lessee Operating Lease Liability Payments Due Year Five

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive


Lessee
Period End2020-12-31
Value3145000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearFive100.0
Percentage of Assets0.1

Lessee Operating Lease Liability Payments Due After Year Five

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive


Lessee
Period End2020-12-31
Value14
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive100.0
Percentage of Assets0.6

Operating Lease Liability

us-gaap:OperatingLeaseLiability

us-gaap:OperatingLeaseLiability


Operating
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312019-09-302019-06-302019-03-31
Value4042383739363033
Percentage of OperatingLeaseLiability100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.71.71.61.61.71.51.21.3

Lessee Operating Lease Liability Payments Due

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value49514745
Percentage of LesseeOperatingLeaseLiabilityPaymentsDue100.0100.0100.0100.0
Percentage of Assets2.02.01.91.9

Lessee Operating Lease Liability Undiscounted Excess Amount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value8338000.08595000.08476000.08531000.0
Percentage of LesseeOperatingLeaseLiabilityUndiscountedExcessAmount100.0100.0100.0100.0
Percentage of Assets0.30.30.30.4

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-312009-12-312008-12-31
Value167116141791184320461979197083481984289391783587687031432017914615115416010211123310.359
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets67.669.973.171.374.070.765.354.754.266.469.069.161.663.063.049.149.161.958.565.766.970.167.969.329.60.00.0

us-gaap:StockholdersEquity us-gaap:BusinessAcquisition

opk:BioReference


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312015-12-31
Value1095107710009688851000
Percentage of StockholdersEquity0.00.059.80.054.850.5
Percentage of Assets45.242.740.440.838.335.7
Percentage of Assets opk:BioReference0.00.00.00.00.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-31
Value-4.225-22.07-20.131-0.528-27.009
Percentage of StockholdersEquity-0.3-1.4-1.1-0.0-1.3
Percentage of Assets-0.2-1.0-0.8-0.0-1.0
Percentage of Assets us-gaap:AccumulatedOtherComprehensiveIncome0.00.00.00.00.0

us-gaap:AccumulatedTranslationAdjustment


Stockholders
Period End2021-06-302021-03-312020-12-312019-12-312018-12-312017-12-31
Value-9.932-13.295-4.225-22.07-20.131-5.404
Percentage of StockholdersEquity0.00.0-0.3-1.4-1.1-0.3
Percentage of Assets-0.4-0.5-0.2-1.0-0.8-0.2
Percentage of Assets us-gaap:AccumulatedTranslationAdjustment0.00.00.00.00.00.0

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value31523142300428892845565524376367307
Percentage of StockholdersEquity188.6194.6167.7156.7139.0315.1326.21631.11161.585654.0
Percentage of Assets127.5136.1122.6111.8102.8195.0228.7483.00.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value6.7066.7045.8695.65.5863.0562.9752.5542.5381.991
Percentage of StockholdersEquity0.40.40.30.30.31.71.811.18.0554.6
Percentage of Assets0.30.30.20.20.21.11.33.30.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value-1481.833-1511.077-1197.078-1048.914-775.329-388.77-359.722-358.379-339.229-309.116
Percentage of StockholdersEquity-88.7-93.6-66.8-56.9-37.9-216.7-223.6-1554.7-1073.5-86104.7
Percentage of Assets-59.9-65.4-48.8-40.6-28.0-134.1-156.7-460.40.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.0

us-gaap:TreasuryStock


Stockholders
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312012-12-312011-12-312010-12-312009-12-312008-12-31
Value-1.791-1.791-1.791-1.791-1.911-7.457-8.092-0.061-0.061-0.024
Percentage of StockholdersEquity-0.1-0.1-0.1-0.1-0.1-4.2-5.0-0.3-0.2-6.7
Percentage of Assets-0.1-0.1-0.1-0.1-0.1-2.6-3.5-0.10.00.0
Percentage of Assets us-gaap:TreasuryStock0.00.00.00.00.00.00.00.00.00.0

Stockholders Equity Including Portion Attributable To Noncontrolling Interest

us-gaap:StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest

us-gaap:StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-312010-12-31
Value17421696167116231588154816141641170817621791178818101823188520892106210620912105201519971979196982681283588791283187286731231917816023
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets72.067.367.668.568.469.469.969.369.668.473.172.171.570.772.976.776.176.375.675.272.771.570.765.354.253.765.968.568.861.362.762.848.748.961.770.129.6

us-gaap:StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312015-12-312014-12-312013-12-312013-09-302012-12-312011-12-312010-12-31
Value-9.932-13.295-4.225-17.451-25.752-30.187-22.07-28.774-20.351-23.229-20.131-13.138-13.004-0.539-0.528-5.422-14.07-24.953-27.009-22.537-12.3923.4183.2377.3560.9072.921
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest-0.6-0.8-0.3-1.1-1.6-1.9-1.4-1.8-1.2-1.3-1.1-0.7-0.7-0.0-0.0-0.3-0.7-1.2-1.3-1.1-1.50.40.44.10.612.7
Percentage of Assets-0.4-0.5-0.2-0.7-1.1-1.4-1.0-1.2-0.8-0.9-0.8-0.5-0.5-0.0-0.0-0.2-0.5-0.9-1.0-0.8-1.00.20.22.50.43.8
Percentage of Assets us-gaap:AccumulatedOtherComprehensiveIncome0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AccumulatedTranslationAdjustment


Stockholders
Period End2020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312014-12-31
Value-17.451-25.752-30.187-22.07-28.774-20.351-23.229-20.131-13.138-13.004-0.539-5.404-6.482-15.04-25.536-26.746-16.485-19.281-14.848-21.791-6.717
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest-1.1-1.6-1.9-1.4-1.8-1.2-1.3-1.1-0.7-0.7-0.0-0.3-0.3-0.7-1.2-1.3-0.8-1.0-0.7-1.1-0.8
Percentage of Assets-0.7-1.1-1.4-1.0-1.2-0.8-0.9-0.8-0.5-0.5-0.0-0.2-0.2-0.5-0.9-1.0-0.6-0.7-0.5-0.8-0.5
Percentage of Assets us-gaap:AccumulatedTranslationAdjustment0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-312010-12-31
Value32143155315231503147314531423065306130583004290729012895288928452705152913791357742739565524376
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest184.5186.0188.6194.0198.1203.1194.6186.7179.2173.5167.7162.5160.2158.8153.2136.0136.6183.0158.0156.4237.5231.3315.9326.21631.1
Percentage of Assets132.7125.2127.5132.9135.4140.9136.1129.4124.6118.8122.6117.2114.6112.3111.8102.896.6120.699.198.1115.8113.1195.0228.7483.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-312010-12-31
Value6.8986.7076.7066.7066.7046.7046.7046.1626.1626.1625.8695.6045.6025.65.65.5865.4624.3344.1484.0893.3913.3883.0562.9752.554
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest0.40.40.40.40.40.40.40.40.40.30.30.30.30.30.30.30.30.50.50.51.11.11.71.811.1
Percentage of Assets0.30.30.30.30.30.30.30.30.30.20.20.20.20.20.20.20.20.30.30.30.50.51.11.33.3
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-312010-12-31
Value-1466.941-1450.755-1481.833-1514.131-1537.848-1571.551-1511.077-1398.727-1336.72-1276.914-1197.078-1121.007-1093.353-1087.152-1007.159-729.954-704.871-674.843-503.177-486.377-426.379-422.985-388.77-359.722-358.379
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest-84.2-85.5-88.7-93.2-96.8-101.5-93.6-85.2-78.2-72.4-66.8-62.7-60.4-59.6-53.4-34.9-35.6-80.7-57.6-56.0-136.4-132.3-217.3-223.6-1554.7
Percentage of Assets-60.6-57.6-59.9-63.9-66.2-70.4-65.4-59.0-54.4-49.6-48.8-45.2-43.2-42.2-39.0-26.4-25.2-53.2-36.2-35.2-66.5-64.7-134.1-156.7-460.4
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:TreasuryStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-312010-12-31
Value-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.791-1.911-3.645-4.051-7.362-7.457-7.457-7.457-7.457-8.092-0.061
Percentage of StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.5-0.8-0.9-2.4-2.3-4.2-5.0-0.3
Percentage of Assets-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.3-0.5-0.5-1.2-1.1-2.6-3.5-0.1
Percentage of Assets us-gaap:TreasuryStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value6898000.06707000.06706000.06706000.06704000.06704000.06704000.06162000.06162000.06162000.05869000.05604000.05602000.05600000.05600000.05600000.05600000.05596000.05586000.05581000.05483000.05480000.05462000.05459000.04646000.04593000.04334000.04329000.04271000.04154000.04148000.04089000.03391000.03388000.03056000.02982000.02980000.02976000.02975000.02881000.02879000.02554000.0
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.30.30.30.30.30.30.30.30.30.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.30.30.30.30.30.30.30.30.50.51.11.21.31.31.31.91.83.3

Additional Paid In Capital

us-gaap:AdditionalPaidInCapital

us-gaap:AdditionalPaidInCapital


Additional
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value32143155315231503147314531423065306130583004290729012895288928832863285628452834273627282705269616871628152915231490138413791357742739565529528526524485482376
Percentage of AdditionalPaidInCapital100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets132.7125.2127.5132.9135.4140.9136.1129.4124.6118.8122.6117.2114.6112.3111.8105.9103.4103.5102.8101.298.797.796.689.4110.6107.7120.6117.6112.3102.199.198.1115.8113.1195.0212.0229.3227.2228.7321.3301.0483.0

Retained Earnings Accumulated Deficit

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:RetainedEarningsAccumulatedDeficit


Retained
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value-1466900000.0-1450800000.0-1481800000.0-1514100000.0-1537800000.0-1571600000.0-1511100000.0-1398700000.0-1336700000.0-1276900000.0-1197100000.0-1109000000.0-1081400000.0-1075200000.0-1007200000.0-792380000.0-745940000.0-728410000.0-729950000.0-716290000.0-701320000.0-716850000.0-704870000.0-706470000.0-834720000.0-791960000.0-674840000.0-621870000.0-573200000.0-547730000.0-503180000.0-486380000.0-426380000.0-422980000.0-388770000.0-388220000.0-378580000.0-368330000.0-359720000.0-378120000.0-369890000.0-358380000.0
Percentage of RetainedEarningsAccumulatedDeficit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets-60.6-57.6-59.9-63.9-66.2-70.4-65.4-59.0-54.4-49.6-48.8-44.7-42.7-41.7-39.0-29.1-26.9-26.4-26.4-25.6-25.3-25.7-25.2-23.4-54.7-52.4-53.2-48.0-43.2-40.4-36.2-35.2-66.5-64.7-134.1-155.3-164.3-159.1-156.7-250.4-230.6-460.4

Accumulated Other Comprehensive Income Loss Net Of Tax

us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax

us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax


Accumulated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value-9932000.0-13295000.0-4225000.0-17451000.0-25752000.0-30187000.0-22070000.0-28774000.0-20351000.0-23229000.0-20131000.0-13138000.0-13004000.0-539000.0-528000.0-5422000.0-14070000.0-24953000.0-27009000.0-16284000.0-23431000.0-17110000.0-22537000.0-20992000.0-18880000.0-17503000.0-12392000.0-8697000.0304000.01399000.03418000.03237000.02830000.08093000.07356000.09004000.06722000.02406000.0907000.0434000.03157000.02921000.0
Percentage of AccumulatedOtherComprehensiveIncomeLossNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets-0.4-0.5-0.2-0.7-1.1-1.4-1.0-1.2-0.8-0.9-0.8-0.5-0.5-0.0-0.0-0.2-0.5-0.9-1.0-0.6-0.8-0.6-0.8-0.7-1.2-1.2-1.0-0.70.00.10.20.20.41.22.53.62.91.00.40.32.03.8

Treasury Stock Value

us-gaap:TreasuryStockValue

us-gaap:TreasuryStockValue


Treasury
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302010-12-31
Value1.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.7911.9111.9111.9111.9111.9113.6453.6453.6454.0514.0514.0514.0517.37.3627.4577.4577.4577.4577.4578.0928.0928.0927.8937.8930.061
Percentage of TreasuryStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.10.20.30.30.30.30.50.50.51.21.12.63.03.53.53.55.24.90.1

Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue


Adjustments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312013-12-312013-09-302013-06-302013-03-31
Value3.462.6472.172.741.5862.4512.4143.4283.1224.4575.175.0775.5785.9363.5720.4081.7985.205
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Adjustments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312013-12-312013-09-302013-06-302013-03-31
Value3.462.6472.172.741.5862.4512.4143.4283.1224.4575.175.0775.5785.9363.5720.4081.7985.205
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-15.453263463-14.423-43.37-46.037-23.866-53.631-48.988-34.659-21.883-17.079-35.522.11-37.607-22.664-33.91930-31.89642-9.206-9.351-31.363-34.055238-24.761-21.077-15.495-29.046-26.05-11.472-5.925-14.745-5.728-1.927-6.261-11.499-6.588-3.346-3.881-4.685-1.456-5.97
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.54.86.914.7-4.8-20.5-20.5-10.4-23.7-22.0-15.6-8.8-6.5-16.81.3-15.3-7.7-14.88.9-12.316.1-3.6-4.2-30.2-1784.911541.5-1202.0-849.2-719.7-1474.4-998.8-414.2-185.9-476.9-404.2-1927.00.00.00.00.00.00.00.00.0

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-8.842-1.106-6.7445.501-11.465-5.619-3.756-2.191-3.191-4.132-2.882-11.571-6.52-5.146-13.954-16.301-9.97-6.442-6.47919-23.647-10.062-7.9377.174-98.095-0.363-0.799-1.545-3.067-0.2643845-53.199-0.6498.43-10.801-4.526-17.87239124.55-70.629-0.82710
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2.0-0.2-1.41.3-3.8-2.7-1.7-1.0-1.4-1.9-1.3-4.6-2.5-2.4-8.7-6.6-3.4-2.8-1.97.5-8.9-4.0-3.66.9-5141.2-17.5-38.8-62.2-142.5-13.41490.51635.1-1668.7-21.0594.9-10801.00.00.00.00.00.00.00.00.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value0.265-7.1928.108-54.46112-1.61170-19.995-39.27616390-3.0054.02494.22622312.1741.7780.96-37.9860.053-0.171144.67134.1297.135-3.905-0.096172.813-3.3171691.048-1.7741.8794.878-8.356-0.146-9.7441055.6041.373
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.1-1.31.6-12.74.3-0.831.5-8.7-17.473.740.9-1.21.523.32.69.310.81.00.50.4-14.30.0-0.114.1244.8667.6200.4287.5-181.4-4.9653.3101.6-104.05486.474.0-1774.00.00.00.00.00.00.00.00.0

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-23.746173514-12.918-50.92220-46.448-96.13511052-36.663-19.5628.444
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-5.43.27.33.4-4.3-24.19.3-20.3-42.549.823.8-14.7-7.44.0

Amortization Of Financing Costs

us-gaap:AmortizationOfFinancingCosts

us-gaap:AmortizationOfFinancingCosts


Amortization
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value202000.0222000.0221000.0215000.0208000.0203000.0489000.0198000.0-97000.0405000.032000.056000.056000.043000.056000.056000.056000.056000.062000.0101000.037000.037000.037000.0280000.0144000.0751000.0100000.0100000.01630000.0177000.0177000.0650000.0198000.0145000.000
Percentage of AmortizationOfFinancingCosts100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.0

us-gaap:AmortizationOfFinancingCosts us-gaap:LongtermDebtType

us-gaap:SeniorNotes


Amortization
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value186000.0208000.0206000.0199000.0193000.0188000.0185000.0180000.0172000.097000.014000.037000.037000.037000.037000.0
Percentage of AmortizationOfFinancingCosts92.193.793.292.692.892.637.890.9-177.324.043.866.166.186.066.1

Deferred Income Tax Expense Benefit

us-gaap:DeferredIncomeTaxExpenseBenefit

us-gaap:DeferredIncomeTaxExpenseBenefit


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value3.512-1.033130.9460.4150.6132.2591.8970.52-0.352-20.605-12.5150.683-2.70962-23.327-13.803-9.236-30.502-21.98313-22.244-26.823-96.7130.00.0-1.0180.00.00.00.7960.405-0.70.098-9.9580.0
Percentage of DeferredIncomeTaxExpenseBenefit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.0100.00.00.00.0100.0100.0100.0100.0100.00.0

Depreciation Depletion And Amortization

us-gaap:DepreciationDepletionAndAmortization

us-gaap:DepreciationDepletionAndAmortization


Depreciation
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value2019202122222223232323232424252525252325242222124.1523.5253.6583.6784.0273.5644.5683.7683.4513.4292.7132.6622.3662.3280.9721.040.9360.8690.495-0.252
Percentage of DepreciationDepletionAndAmortization100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DepreciationDepletionAndAmortization us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments

us-gaap:OperatingSegments, opk:Diagnostics


Depreciation
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value13121213151415161616161617171818181818182119189.6021.7541.7471.7581.7291.7161.6911.7231.7171.7041.6891.1040.841
Percentage of DepreciationDepletionAndAmortization65.962.962.965.268.067.466.767.768.768.368.670.672.672.771.872.673.773.677.372.887.887.084.877.442.249.648.147.042.647.437.745.649.449.340.731.6

us-gaap:OperatingSegments, opk:Pharmaceutical


Depreciation
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value7.0077.4137.4457.3167.1197.1217.4937.6737.3827.5267.4937.0216.7526.747.1096.9356.6946.7755.4136.9942.9872.8613.3432.7752.3711.7561.8751.9252.2871.8492.8172.021.7021.6951.5621.78
Percentage of DepreciationDepletionAndAmortization34.137.137.134.832.032.333.332.231.231.631.329.427.327.228.027.326.226.322.627.112.212.915.122.457.149.851.352.356.851.961.753.649.349.457.666.9

Increase Decrease In Accounts Payable

us-gaap:IncreaseDecreaseInAccountsPayable

us-gaap:IncreaseDecreaseInAccountsPayable


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-73.882623320-11.888-4.865-14.961179.1743.713-16.754-1.2372.114-10.2068.1582.574-10.119-3.678-2.936-12.856-0.34917-42.6054.9942.107-0.002-0.542-4.7871.479-0.4741.970.436-0.1031.5780.465-0.525-0.2711.8680.596-2.099-2.1490.1260.041
Percentage of IncreaseDecreaseInAccountsPayable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Increase Decrease In Accounts Receivable

us-gaap:IncreaseDecreaseInAccountsReceivable

us-gaap:IncreaseDecreaseInAccountsReceivable


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-55.59354325800.763-4.119-7.6553.9590.439-12.6964.739-5.683-6.757-71.605-17.2711317-3.337108.4649.924159.24.7090.103-0.221-0.1813.7640.557-1.478-0.9281.0940.558-0.947-2.497-0.012.691-0.8040.4491.5510.5230.0410.237
Percentage of IncreaseDecreaseInAccountsReceivable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Increase Decrease In Inventories

us-gaap:IncreaseDecreaseInInventories

us-gaap:IncreaseDecreaseInInventories


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-24.095271738138.8312.593.3183.752.475-0.533-3.163-0.69-0.2045.268-2.1720.3930.053.8810.9631.6110.152-0.5283.150.6472.610.653-0.314-0.2631.676-0.940.261-2.6521.4391.3641.122-1.1124.4331.91-0.863-1.535-1.6824.6012.385
Percentage of IncreaseDecreaseInInventories100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-15.453263463-14.423-43.37-46.037-23.866-53.631-48.988-34.659-21.883-17.079-35.522.11-37.607-22.664-33.91930-31.89642-9.206-9.351-31.363-34.055238-24.761-21.077-15.495-29.046-26.05-11.472-5.925-14.745-5.728-1.927-6.261-11.499-6.588-3.346-3.881-4.685-1.456-5.97
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.54.86.914.7-4.8-20.5-20.5-10.4-23.7-22.0-15.6-8.8-6.5-16.81.3-15.3-7.7-14.88.9-12.316.1-3.6-4.2-30.2-1784.911541.5-1202.0-849.2-719.7-1474.4-998.8-414.2-185.9-476.9-404.2-1927.00.00.00.00.00.00.00.00.0

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-302010-06-30
Value-16.18631322333-59.132-112.35-62.007-59.806-80.762-76.07-27.655-6.201-43.114-52.971-48.669-25.48-44.551-16.8-59.998-3.394-34.215-0.548-9.646-10.245-8.61118-8.236-5.746-5.704-0.673-7.354-6.215
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.75.76.55.511.2-28.0-50.1-27.1-26.4-36.3-34.3-11.1-2.4-20.4-2571.4-1960.9-1183.5-2261.5-644.2-2166.0-106.5-1106.6-38.7-9646.00.00.00.00.00.00.00.00.00.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312013-12-312013-09-302013-06-302013-03-31
Value-16.18631322333-59.132-112.35-62.007-59.806-80.762-76.071-27.655-6.201-43.114-16.8-59.998-3.394-34.215
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3.75.76.55.511.2-28.0-50.1-27.1-26.4-36.3-34.3-11.1-2.4-20.4-644.2-2166.0-106.5-1106.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Profit Loss

us-gaap:ProfitLoss

us-gaap:ProfitLoss


Profit
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-31
Value2333-59.132-62.007-59.806-80.762-76.07-27.655-6.201-43.114-213.905-46.442-17.528-30.995-13.661-14.97715-11.9781.603128-43.241-118.037-53.461-50.014-26.075-45.091-17.429-60.801-4.353-34.762-1.04-9.646-10.245-8.611
Percentage of ProfitLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.511.2-28.0-27.1-26.4-36.3-34.3-11.1-2.4-20.4-132.9-18.9-6.0-13.6-4.0-5.85.8-4.70.7123.4-2266.3-5705.0-2595.2-2015.1-1211.1-2288.9-668.3-2195.0-136.5-1124.3-73.4-9646.00.00.0

us-gaap:ProfitLoss us-gaap:EquityMethodInvestmentNonconsolidatedInvestee

us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees


Profit
Period End2021-06-302021-03-312020-12-312020-09-30
Value4.2-10.1-24.2-24.6
Percentage of ProfitLoss0.00.00.0-103.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.9-1.9-4.9-5.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:EquityMethodInvestmentNonconsolidatedInvesteeOrGroupOfInvestees0.00.00.00.0

Share Based Compensation

us-gaap:ShareBasedCompensation

us-gaap:ShareBasedCompensation


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value3.462.6472.172.741.5862.4512.4143.4283.1224.4575.175.0775.5785.9366.0156.4926.1079.6937.7618.8348.798178.3093.6756.7087.3824.6913.13.43.5793.5720.41.85.2051.851.10.9891.181.6031.8521.8521.6462.7111.066
Percentage of ShareBasedCompensation100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-8.842-1.106-6.7445.501-11.465-5.619-3.756-2.191-3.191-4.132-2.882-11.571-6.52-5.146-13.954-16.301-9.97-6.442-6.47919-23.647-10.062-7.9377.174-98.095-0.363-0.799-1.545-3.067-0.2643845-53.199-0.6498.43-10.801-4.526-17.87239124.55-70.629-0.82710
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2.0-0.2-1.41.3-3.8-2.7-1.7-1.0-1.4-1.9-1.3-4.6-2.5-2.4-8.7-6.6-3.4-2.8-1.97.5-8.9-4.0-3.66.9-5141.2-17.5-38.8-62.2-142.5-13.41490.51635.1-1668.7-21.0594.9-10801.00.00.00.00.00.00.00.00.0

Payments To Acquire Productive Assets

us-gaap:PaymentsToAcquireProductiveAssets

us-gaap:PaymentsToAcquireProductiveAssets


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value8.9479.2456.7979.736115.6263.8752.4343.52.9323.035126.8195.97314157.2689.5371.5324.1493.0549.8126.4242.9831.0760.3630.7991.4681.6060.8610.9710.9371.2990.7550.4080.6560.2330.1750.7040.7070.4340.1080.1730.091
Percentage of PaymentsToAcquireProductiveAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value0.265-7.1928.108-54.46112-1.61170-19.995-39.27616390-3.0054.02494.22622312.1741.7780.96-37.9860.053-0.171144.67134.1297.135-3.905-0.096172.813-3.3171691.048-1.7741.8794.878-8.356-0.146-9.7441055.6041.373
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.1-1.31.6-12.74.3-0.831.5-8.7-17.473.740.9-1.21.523.32.69.310.81.00.50.4-14.30.0-0.114.1244.8667.6200.4287.5-181.4-4.9653.3101.6-104.05486.474.0-1774.00.00.00.00.00.00.00.00.0

Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice


Share
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value6.458.019.3110.0810.189.555.54.472.92.64
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Deferred Tax Liabilities

us-gaap:DeferredTaxLiabilities

us-gaap:DeferredTaxLiabilities


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value1311171151481632261641659.4436.863
Percentage of DeferredTaxLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxLiabilities us-gaap:BalanceSheetLocation

us-gaap:OtherAssets


Deferred
Period End2020-12-312016-12-31
Value5.32.312
Percentage of DeferredTaxLiabilities4.01.4

Unrecognized Tax Benefits

us-gaap:UnrecognizedTaxBenefits

us-gaap:UnrecognizedTaxBenefits


Unrecognized
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-312010-12-312009-12-31
Value14171721278.5955.899.2319.2455.255.4136.818
Percentage of UnrecognizedTaxBenefits100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Deferred Tax Assets Valuation Allowance

us-gaap:DeferredTaxAssetsValuationAllowance

us-gaap:DeferredTaxAssetsValuationAllowance


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value3031941541425542131855953
Percentage of DeferredTaxAssetsValuationAllowance100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:AllowanceForDoubtfulAccountsProvisionForAllowanceAsPercentOfGrossSales us-gaap:ProductOrService

opk:AllowanceForDoubtfulAccountsProvisionForAllowanceAsPercentOfGrossSales

opk:Rayaldee


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-312019-09-30
Value69.063.0-2.063.00.62-0.030.63
Percentage of AllowanceForDoubtfulAccountsProvisionForAllowanceAsPercentOfGrossSales100.0100.0100.0100.0100.0100.0100.0

opk:AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments us-gaap:ProductOrService

opk:AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments

opk:Rayaldee


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value9.8851015111212128.234-7.941-6.103-5.106-3.749-2.62-1.945
Percentage of AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments us-gaap:ProductOrService, us-gaap:ValuationAllowancesAndReservesType

opk:Rayaldee, opk:ChargebacksDiscountsRebatesAndFees


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value3.7164.4543.9044.9654.4415.1563.8993.335-2.549-2.062-1.591-1.333-0.892-0.805
Percentage of AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments37.643.824.842.634.442.531.240.532.133.831.235.634.041.4

opk:Rayaldee, opk:Governmental


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value5.6845.297116.5228.2736.858.474.622-5.009-3.255-3.412-2.35-1.602-0.955
Percentage of AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments57.552.170.556.064.156.567.756.163.153.366.862.761.149.1

opk:Rayaldee, opk:SalesReturns


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value0.4850.4190.7540.1590.1880.1220.1390.277-0.383-0.786-0.103-0.066
Percentage of AllowanceForDoubtfulAccountsReceivableDecreaseCreditsOrPayments4.94.14.81.41.51.01.13.44.812.92.01.8

opk:COVID19NumberOfTestsPerformed opk:COVID19TestType

opk:COVID19NumberOfTestsPerformed

opk:DiagnosticMolecularTest


C
Period End2020-09-302020-06-30
Value3500000.02200000.0
Percentage of COVID19NumberOfTestsPerformed100.0100.0

opk:SerologyAntibodyTest


C
Period End2020-09-302020-06-30
Value300000.0331600.0
Percentage of COVID19NumberOfTestsPerformed8.615.1

opk:COVID19PercentOfTotalTestVolume

opk:COVID19PercentOfTotalTestVolume


C
Period End2020-09-30
Value63.0
Percentage of COVID19PercentOfTotalTestVolume100.0

opk:ChangeInTestingVolumePercent opk:TestingType

opk:ChangeInTestingVolumePercent

opk:GenomicTest


Change
Period End2021-06-302021-03-31
Value28.710.3
Percentage of ChangeInTestingVolumePercent100.0100.0

opk:RoutineClinicalTest


Change
Period End2021-06-302021-03-31
Value20.2-6.8
Percentage of ChangeInTestingVolumePercent70.4-66.0

opk:ChangeInTestingVolumePercent us-gaap:StatementBusinessSegments

opk:Diagnostics


Change
Period End2020-09-30
Value-9.1
Percentage of ChangeInTestingVolumePercent0.0

opk:CollaborativeArrangementDevelopmentMilestonePayment us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:SubsequentEventType

opk:CollaborativeArrangementDevelopmentMilestonePayment

opk:CAMP4, opk:DravetSyndromeProducts, us-gaap:SubsequentEvent


Collaborative
Period End2021-07-06
Value3500000.0
Percentage of CollaborativeArrangementDevelopmentMilestonePayment100.0

opk:CAMP4, opk:NonDravetSyndromeProducts, us-gaap:SubsequentEvent


Collaborative
Period End2021-07-06
Value4000000.0
Percentage of CollaborativeArrangementDevelopmentMilestonePayment114.3

opk:CollaborativeArrangementPercentOfOutstandingShares us-gaap:CounterpartyName, us-gaap:SubsequentEventType

opk:CollaborativeArrangementPercentOfOutstandingShares

opk:CAMP4, us-gaap:SubsequentEvent


Collaborative
Period End2021-07-06
Value5.0
Percentage of CollaborativeArrangementPercentOfOutstandingShares100.0

opk:CollaborativeArrangementSalesMilestonePayment us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:SubsequentEventType

opk:CollaborativeArrangementSalesMilestonePayment

opk:CAMP4, opk:DravetSyndromeProducts, us-gaap:SubsequentEvent


Collaborative
Period End2021-07-06
Value90
Percentage of CollaborativeArrangementSalesMilestonePayment100.0

opk:CAMP4, opk:NonDravetSyndromeProducts, us-gaap:SubsequentEvent


Collaborative
Period End2021-07-06
Value90
Percentage of CollaborativeArrangementSalesMilestonePayment100.0

opk:CollaborativeArrangementUpfrontPayment us-gaap:CounterpartyName, us-gaap:SubsequentEventType

opk:CollaborativeArrangementUpfrontPayment

opk:CAMP4, us-gaap:SubsequentEvent


Collaborative
Period End2021-07-06
Value1.5
Percentage of CollaborativeArrangementUpfrontPayment100.0

opk:GainLossOnConversionOfDebt us-gaap:DebtInstrument, us-gaap:LongtermDebtType

opk:GainLossOnConversionOfDebt

opk:ConvertibleSeniorNotesDue2025, us-gaap:ConvertibleDebt


Gain
Period End2021-05-31
Value-11100000.0
Percentage of GainLossOnConversionOfDebt100.0

opk:IncomeLossfromContinuingOperationsBeforeInvestmentsinInvesteesExtraordinaryItemsNoncontrollingInterestNetofTax

opk:IncomeLossfromContinuingOperationsBeforeInvestmentsinInvesteesExtraordinaryItemsNoncontrollingInterestNetofTax


Income
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-16.119312333-58.998-61.713-59.535-78.908-73.116-25.7811.012-40.658-211.205-42.429-11.9-28.864-11.155-14.16317-9.6332.641131-42.437-116.276-52.361-49.954-25.707-43.035-13.835-59.201-1.982-30.872-0.368-9.361
Percentage of IncomeLossfromContinuingOperationsBeforeInvestmentsinInvesteesExtraordinaryItemsNoncontrollingInterestNetofTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:IncreaseDecreaseInEquitySecuritiesFVNIAndDerivativeInstruments

opk:IncreaseDecreaseInEquitySecuritiesFVNIAndDerivativeInstruments


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-1.1520.2791.354-7.76815-9.2598.43-11.747-7.2561.825-7.822-0.473113.101-1.917-7.555.4824.037
Percentage of IncreaseDecreaseInEquitySecuritiesFVNIAndDerivativeInstruments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:IncreaseDecreaseInRevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService

opk:IncreaseDecreaseInRevenueFromContractWithCustomerExcludingAssessedTax

us-gaap:Service


Increase
Period End2021-06-302021-03-31
Value146336
Percentage of IncreaseDecreaseInRevenueFromContractWithCustomerExcludingAssessedTax100.0100.0

opk:IncreaseDecreaseinForeignCurrencyMeasurement

opk:IncreaseDecreaseinForeignCurrencyMeasurement


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-31
Value-3478000.0946000.0-2403000.01295000.0-2133000.056000.0-218000.016000.0154000.0-23000.0237000.0134000.0-66000.0-11000.0-863000.0378000.0299000.0-69000.057000.0-28000.0-152000.0-253000.0203000.0476000.0-173000.0473000.0
Percentage of IncreaseDecreaseinForeignCurrencyMeasurement100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:InterestExpenseNonoperating

opk:InterestExpenseNonoperating


Interest
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value4.8875.3955.425.5445.4745.4965.4685.7925.5014.7553.9572.9442.7222.2671.831.841.5021.4291.4082.0182.2171.7872.1232.7450.9862.5651.6912.4024.6853.4863.6543.4093.8422.8970.430.393
Percentage of InterestExpenseNonoperating100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:InterestIncomeNonoperating

opk:InterestIncomeNonoperating


Interest
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value6000.05000.03000.01000.05000.0142000.0233000.0350000.0572000.0556000.01129000.043000.027000.039000.0-24000.0249000.0136000.0249000.0137000.0163000.0135000.043000.0228000.013000.05000.08000.0321000.0402000.07000.040000.0139000.088000.090000.059000.065000.049000.0
Percentage of InterestIncomeNonoperating100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:NumberofSalesEmployees

opk:NumberofSalesEmployees


Numberof
Period End2021-06-302021-03-312020-12-31
Value0300.00
Percentage of NumberofSalesEmployees0.0100.00.0

opk:PaymentsForLeases

opk:PaymentsForLeases


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2.4954.8034.7544.8385.685.2365.7845.5076.0356.593
Percentage of PaymentsForLeases100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:ProceedsFromConvertibleDebtConversionFee us-gaap:DebtInstrument, us-gaap:LongtermDebtType

opk:ProceedsFromConvertibleDebtConversionFee

opk:ConvertibleSeniorNotesDue2025, us-gaap:ConvertibleDebt


Proceeds
Period End2021-06-302021-03-312020-12-31
Value0300000.00
Percentage of ProceedsFromConvertibleDebtConversionFee0.0100.00.0

opk:ProceedsFromDevelopmentAndLicenseAgreementMilestonePayment opk:Milestone, us-gaap:CounterpartyName

opk:ProceedsFromDevelopmentAndLicenseAgreementMilestonePayment

opk:RegulatoryAndDevelopment, opk:Nicoya


Proceeds
Period End2021-06-18
Value115
Percentage of ProceedsFromDevelopmentAndLicenseAgreementMilestonePayment100.0

opk:ProceedsFromDevelopmentAndLicenseAgreementUpfrontPayment opk:Milestone, us-gaap:CounterpartyName

opk:ProceedsFromDevelopmentAndLicenseAgreementUpfrontPayment

opk:PhaseThreeInitiation, opk:Nicoya


Proceeds
Period End2021-06-18
Value5000000.0
Percentage of ProceedsFromDevelopmentAndLicenseAgreementUpfrontPayment100.0

opk:ProceedsFromDevelopmentAndLicenseAgreementUpfrontPayment us-gaap:CounterpartyName

opk:Nicoya


Proceeds
Period End2021-06-18
Value5000000.0
Percentage of ProceedsFromDevelopmentAndLicenseAgreementUpfrontPayment100.0

us-gaap:AmortizationOfDebtDiscountPremium us-gaap:LongtermDebtType

us-gaap:AmortizationOfDebtDiscountPremium

us-gaap:SeniorNotes


Amortization
Period End2021-06-302021-03-312020-12-31
Value1710000.01907000.01896000.0
Percentage of AmortizationOfDebtDiscountPremium100.0100.0100.0

us-gaap:AmortizationOfFinancingCostsAndDiscounts us-gaap:LongtermDebtType

us-gaap:AmortizationOfFinancingCostsAndDiscounts

us-gaap:SeniorNotes


Amortization
Period End2021-06-302021-03-312020-12-31
Value1896000.02115000.02102000.0
Percentage of AmortizationOfFinancingCostsAndDiscounts100.0100.0100.0

us-gaap:BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1

us-gaap:BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-0.103-0.957-5.3231.0831.111-0.86-14.776-1.109-3.7754.806-4.411.193-15.3581.7591.052-11.2134.3662.3711.353.093101.753-1.4211.636-0.3395.1750.368191.8762.612.7740.2522.5771.344-1.880.556
Percentage of BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ConcentrationRiskPercentage1 us-gaap:ConcentrationRiskByBenchmark, us-gaap:ConcentrationRiskByType

us-gaap:ConcentrationRiskPercentage1

us-gaap:AccountsReceivable, us-gaap:CustomerConcentrationRisk


Concentration
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-312015-03-312014-03-31
Value0.70.71.00.020.0190.0250.0230.020.0210.0310.0320.0260.0320.10.1
Percentage of ConcentrationRiskPercentage1100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccountsReceivable, us-gaap:GeographicConcentrationRisk


Concentration
Period End2021-03-312020-12-312020-09-302020-06-302020-03-31
Value10.36.38.10.3760.036
Percentage of ConcentrationRiskPercentage11471.4900.0810.01880.0189.5

us-gaap:AccountsReceivable, us-gaap:GovernmentContractsConcentrationRisk


Concentration
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value5.06.07.00.110.040.060.1010.0960.170.1740.1520.1740.1510.158
Percentage of ConcentrationRiskPercentage1714.3857.1700.0550.0210.5240.0439.1480.0809.5561.3475.0669.20.0493.8

us-gaap:ConcentrationRiskPercentage1 us-gaap:MajorCustomers, us-gaap:ConcentrationRiskByBenchmark, us-gaap:ConcentrationRiskByType

opk:FederalAndStateGovernments, us-gaap:AccountsReceivable, us-gaap:CreditConcentrationRisk


Concentration
Period End2021-06-302020-12-31
Value5.06.0
Percentage of ConcentrationRiskPercentage10.0857.1

opk:IndividualPatients, us-gaap:AccountsReceivable, us-gaap:CustomerConcentrationRisk


Concentration
Period End2021-06-302020-12-31
Value1.00.7
Percentage of ConcentrationRiskPercentage10.0100.0

opk:StatesCitiesAndOtherMunicipalities, us-gaap:AccountsReceivable, us-gaap:GeographicConcentrationRisk


Concentration
Period End2021-06-302020-12-31
Value7.16.3
Percentage of ConcentrationRiskPercentage10.0900.0

us-gaap:ContractWithCustomerLiabilityRevenueRecognized

us-gaap:ContractWithCustomerLiabilityRevenueRecognized


Contract
Period End2021-06-302021-03-312020-12-312020-06-302020-03-312019-12-312019-03-312018-12-312018-09-302018-06-30
Value6.6350.790.6720.00.00.00.00.05.84.8
Percentage of ContractWithCustomerLiabilityRevenueRecognized100.0100.0100.00.00.00.00.00.0100.0100.0

us-gaap:ContractWithCustomerLiabilityRevenueRecognized us-gaap:ProductOrService

opk:Rayaldee


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value5.05.8108.18.69.9127.45.75.86.05.84.83.7
Percentage of ContractWithCustomerLiabilityRevenueRecognized75.4734.21503.00.00.00.00.00.00.00.00.0100.0100.00.0

us-gaap:ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod

us-gaap:ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value0.528-1.31.4-8.78.9-1.0115.98.4-0.67.70.01535
Percentage of ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0

us-gaap:DebtConversionConvertedInstrumentAmount1 us-gaap:DebtInstrument, us-gaap:LongtermDebtType

us-gaap:DebtConversionConvertedInstrumentAmount1

opk:ConvertibleSeniorNotesDue2025, us-gaap:ConvertibleDebt


Debt
Period End2021-05-31
Value55
Percentage of DebtConversionConvertedInstrumentAmount1100.0

us-gaap:Depreciation

us-gaap:Depreciation


Depreciation
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-31
Value8.07.47.57.17.37.17.17.47.27.37.47.07.57.57.97.37.67.88.07.78.98.78.14.30.90.9
Percentage of Depreciation100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DerivativeGainLossOnDerivativeNet us-gaap:DerivativeInstrumentRisk, us-gaap:HedgingDesignation

us-gaap:DerivativeGainLossOnDerivativeNet

us-gaap:ForwardContracts, us-gaap:Nondesignated


Derivative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-0.246-0.46-0.098-0.483-0.0060.6830.3770.3470.0040.0470.210.1330.332-0.275-0.238-0.379-0.0310.0470.1390.1060.093-0.299-0.0040.1820.110.0710.3090.133-0.0550.0010.074-0.1580.154-0.0210.049-0.032
Percentage of DerivativeGainLossOnDerivativeNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:StockOption, us-gaap:Nondesignated


Derivative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-0.0260.0210.036-0.013-0.007-0.062-0.209-0.368-0.3920.368-0.656-0.2881.9161.671-1.679-0.3420.444-0.9550.466-0.012-3.73-0.986-0.209-4.07-2.4463.8710.8050.651-0.860.5963.392-0.6922.5841.26
Percentage of DerivativeGainLossOnDerivativeNet10.6-4.6-36.72.7116.7-9.1-55.4-106.1-9800.0783.0-312.4-216.5577.1-607.6705.590.2-1432.3-2031.9335.3-11.3-4010.8329.85225.0-2236.3-2223.65452.1260.5489.51563.659600.04583.8438.01677.9-6000.0

us-gaap:DerivativeGainLossOnDerivativeNet us-gaap:HedgingDesignation

us-gaap:Nondesignated


Derivative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-0.272-0.439-0.062-0.496-0.0130.6210.168-0.021-0.3880.415-0.446-0.1552.2481.396-1.917-7.555.4824.0378.667-5.7011.235-1.423-4.98332-16.556-49.788-14.393.30510-10.5152.202-27.79312-23.5490.0310.169
Percentage of DerivativeGainLossOnDerivativeNet110.695.463.3102.7216.790.944.6-6.1-9700.0883.0-212.4-116.5677.1-507.6805.51992.1-17683.98589.46235.3-5378.31328.0475.9124575.017716.5-15050.9-70123.9-4657.02485.0-19940.0-1051500.02975.717590.58214.9112138.163.3-528.1

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents


Effect
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value284000.0-447000.0295000.0631000.082000.0-322000.0-66000.0-396000.0-37000.022000.0-407000.0-204000.0
Percentage of EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:EquitySecuritiesFvNiRealizedGainLoss

us-gaap:EquitySecuritiesFvNiRealizedGainLoss


Equity
Period End2021-06-302021-03-312020-12-31
Value0.02.9811.365
Percentage of EquitySecuritiesFvNiRealizedGainLoss0.0100.0100.0

us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss

us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value-1372000.0-201000.01417000.0-7272000.015787000.0-9880000.0
Percentage of EquitySecuritiesFvNiUnrealizedGainLoss100.0100.0100.0100.0100.0100.0

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings us-gaap:FairValueByLiabilityClass

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings

opk:ContingentConsideration


Fair
Period End2021-06-302021-03-312020-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value-0.102-0.9572.6557.8982.263-4.367-2.371-1.35-3.093-10.758-1.7531.421-1.6350.339-5.175-0.368-19.592-1.876-2.61-2.743
Percentage of FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases us-gaap:FairValueByLiabilityClass

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases

opk:ContingentConsideration


Fair
Period End2021-06-302021-03-312013-12-31
Value-0.0111.1730.0
Percentage of FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases100.0100.00.0

us-gaap:FinanceLeaseInterestExpense

us-gaap:FinanceLeaseInterestExpense


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value500000.0600000.0700000.01100000.0500000.0700000.0800000.0300000.0300000.01700000.0
Percentage of FinanceLeaseInterestExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseInterestPaymentOnLiability

us-gaap:FinanceLeaseInterestPaymentOnLiability


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value12000.033000.047000.063000.041000.045000.068000.072000.043000.0191000.0
Percentage of FinanceLeaseInterestPaymentOnLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeasePrincipalPayments

us-gaap:FinanceLeasePrincipalPayments


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value244000.0525000.0863000.0983000.0533000.0493000.0668000.0575000.0930000.0660000.0
Percentage of FinanceLeasePrincipalPayments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:GainLossOnDerivativeInstrumentsNetPretax

us-gaap:GainLossOnDerivativeInstrumentsNetPretax


Gain
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-0.272-0.439-0.062-0.496-0.0130.6210.168-0.021-0.3880.415-0.446-0.1552.2481.396-1.917-7.555.4824.0378.667-5.7011.235-1.423-4.98332-16.556-49.788-14.393.30510-10.5152.202-27.79312-23.5490.0310.169
Percentage of GainLossOnDerivativeInstrumentsNetPretax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:GainLossOnDispositionOfAssets1

us-gaap:GainLossOnDispositionOfAssets1


Gain
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value0.1073.0390.50910-0.054-0.1020.716-1.2350.064-0.284-0.012
Percentage of GainLossOnDispositionOfAssets1100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:GainLossOnSaleOfInvestments

us-gaap:GainLossOnSaleOfInvestments


Gain
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-31
Value-1.3722.784.41715-9.885.980.21-0.5242.997-1.378-3.4372.4940.0-7.3070.00.00.216-1.44-0.0010.0011.273180.1328.4742.3470.0
Percentage of GainLossOnSaleOfInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.00.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

us-gaap:GoodwillForeignCurrencyTranslationGainLoss

us-gaap:GoodwillForeignCurrencyTranslationGainLoss


Goodwill
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-31
Value1.198-4.444.8074.1962.017-2.3582.367-4.0441.32-1.671-1.738-0.605-5.6572.7921.5263.4986.0851.3870.88-1.9223.934
Percentage of GoodwillForeignCurrencyTranslationGainLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:GoodwillForeignCurrencyTranslationGainLoss us-gaap:BusinessAcquisition, us-gaap:StatementBusinessSegments

opk:EirGenPharmaLimited, opk:Pharmaceutical


Goodwill
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-31
Value1.123-3.9984.0223.6911.702-1.6022.224-3.3821.132-1.683-1.192-0.588-4.7652.5641.2292.9145.5191.2060.791-1.873.443
Percentage of GoodwillForeignCurrencyTranslationGainLoss93.790.083.788.084.467.994.083.685.8100.768.697.284.291.880.583.390.787.089.997.387.5

opk:OPKOHealthEurope, opk:Pharmaceutical


Goodwill
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-31
Value0.1-0.3540.3560.3270.151-0.1420.196-0.2990.1-0.149-0.105-0.05-0.4240.2270.1090.2580.4880.1070.071-0.1660.296
Percentage of GoodwillForeignCurrencyTranslationGainLoss8.38.07.47.87.56.08.37.47.68.96.08.37.58.17.17.48.07.78.18.67.5

opk:OpkoChile, opk:Pharmaceutical


Goodwill
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-31
Value-0.025-0.0880.4290.1780.164-0.614-0.054-0.3240.0210.091-0.253-0.029-0.4050.0980.2010.185-0.0140.0460.0340.1140.195
Percentage of GoodwillForeignCurrencyTranslationGainLoss-2.12.08.94.28.126.0-2.38.01.6-5.414.64.87.23.513.25.3-0.23.33.9-5.95.0

us-gaap:IncomeLossFromEquityMethodInvestments

us-gaap:IncomeLossFromEquityMethodInvestments


Income
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value-67000.0-43000.0-110000.0-189000.0-134000.0-294000.0-271000.0-1854000.0-2955000.0-1874000.0-7213000.0-2456000.0-2700000.0-4013000.0-5628000.0-2131000.0-2505000.0-814000.0-1988000.0-2345000.0-1038000.0-3502000.0-804000.0-1761000.0-1101000.0-60000.0-370000.0-2056000.0-3595000.0-1600000.0-2371000.0-3890000.0-598000.0-468000.0
Percentage of IncomeLossFromEquityMethodInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInAccruedLiabilities

us-gaap:IncreaseDecreaseInAccruedLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-22.034-27.126-7.1641433.8481.002-2.333-10.155126.27411-6.991-8.82942-8.05512-16.024322.5632013-27.28634-1.6724.4136.61.9974.344-8.007-6.1492.3375.031-0.441.9020.546-1.341.253-1.2641.755-0.563-0.34-0.127-0.771
Percentage of IncreaseDecreaseInAccruedLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInContractWithCustomerLiability

us-gaap:IncreaseDecreaseInContractWithCustomerLiability


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-6.635-0.79-0.672-0.6915.425-9.451-12.442-19.845-18.942-18.073-10.733-19.719-15.454-15.358-9.105-18.649
Percentage of IncreaseDecreaseInContractWithCustomerLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInOtherOperatingAssets

us-gaap:IncreaseDecreaseInOtherOperatingAssets


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value-133000.0-1255000.0177000.0209000.0121000.0-60000.0-169000.0-104000.0-379000.0243000.0-4564000.04487000.015000.0131000.01923000.0195000.019000.0235000.01497000.01134000.0715000.0-1447000.01567000.0-1774000.03000.0509000.07843000.0-554000.0-2482000.0-1429000.01069000.0-428000.0-26000.0-71000.0438000.0-66000.0-4000.0-7000.037000.0-35000.062000.0-80000.05000.087000.0
Percentage of IncreaseDecreaseInOtherOperatingAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value15-1.415-7.393-15.731.890.7298.935.032-2.5220.046-6.580.5749.175-5.445-13.0286.5491.0-4.692-41.572107.4266.8830.1665.367-0.198-0.9440.305-0.163-2.179-1.145-0.95-0.4910.0022.571.565-0.0060.8370.4810.167-0.317-0.0160.109-0.533-0.253
Percentage of IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InventoryWriteDown

us-gaap:InventoryWriteDown


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-31
Value900000.03100000.01000000.01700000.01100000.0600000.0900000.0100000.0800000.0500000.0400000.0300000.01200000.00400000.0200000.0200000.04600000.0-200000.00200000.00243000.0-27000.0490000.0220000.0309000.0190000.0246000.0337000.0486000.0256000.0334000.0939000.01168000.0
Percentage of InventoryWriteDown100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.00.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:LitigationSettlementAmountAwardedToOtherParty us-gaap:LitigationStatus

us-gaap:LitigationSettlementAmountAwardedToOtherParty

us-gaap:PendingLitigation


Litigation
Period End2020-08-14
Value3.1
Percentage of LitigationSettlementAmountAwardedToOtherParty100.0

us-gaap:SettledLitigation


Litigation
Period End2021-01-312020-09-222020-05-31
Value1.21116
Percentage of LitigationSettlementAmountAwardedToOtherParty0.00.00.0

us-gaap:LitigationSettlementAmountAwardedToOtherParty us-gaap:LitigationStatus, us-gaap:SubsequentEventType

us-gaap:SettledLitigation, us-gaap:SubsequentEvent


Litigation
Period End2021-04-282021-01-31
Value161.2
Percentage of LitigationSettlementAmountAwardedToOtherParty0.00.0

us-gaap:OperatingLeaseCost

us-gaap:OperatingLeaseCost


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value4.64.54.14.05.14.64.95.54.15.7
Percentage of OperatingLeaseCost100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingLeasePayments

us-gaap:OperatingLeasePayments


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2.2394.2453.8443.7925.1064.6985.0484.865.0625.742
Percentage of OperatingLeasePayments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent

us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent


Other
Period End2021-06-302021-03-312020-06-302020-03-31
Value3363000.0-9070000.04435000.0-8117000.0
Percentage of OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent100.0100.0100.0100.0

us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent

us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent


Other
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312013-12-312013-09-302013-06-302013-03-31
Value3.363-9.078.3014.435-8.1176.704-8.4232.878-3.098-6.993-0.134-12.4654.8650.1810.407-5.2630.737
Percentage of OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Other
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312013-12-31
Value3.363-9.078.3014.435-8.1176.704-8.4232.878-3.098-6.993-0.134-12.4654.8650.181
Percentage of OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccumulatedTranslationAdjustment


Other
Period End2021-06-302021-03-31
Value3.363-9.07
Percentage of OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent100.0100.0

us-gaap:PaidInKindInterest

us-gaap:PaidInKindInterest


Paid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value2396000.02585000.02355000.02617000.02539000.02483000.04173000.01690000.0-142000.03010000.01344000.01361000.01355000.0843000.0631000.0650000.0654000.0640000.0636000.0655000.0659000.0749000.0436000.0495000.0625000.01056000.01066000.01039000.01780000.01777000.01730000.01130000.01817000.01303000.000
Percentage of PaidInKindInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.0

us-gaap:ProceedsFromIssuanceOfDebt us-gaap:DebtInstrument

us-gaap:ProceedsFromIssuanceOfDebt

opk:DistributionToHealthcareProvidersCOVID19


Proceeds
Period End2021-03-312020-12-312020-09-302020-06-30
Value160.010.06.2
Percentage of ProceedsFromIssuanceOfDebt100.00.0100.0100.0

us-gaap:ProceedsFromIssuanceOrSaleOfEquity

us-gaap:ProceedsFromIssuanceOrSaleOfEquity


Proceeds
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302012-03-312011-12-312011-09-302011-06-302011-03-312010-12-312010-09-30
Value0.1580.3080.6690.00.00.00.0-0.0030.00.8550.3180.00.2160.00.051.8662.4644.2-0.2422.1540.7417.8144.654120.8629.3191.1081.639183.5420.5240.9950.5770.211.4610.0310.470.4660.1730.1350.0480.0
Percentage of ProceedsFromIssuanceOrSaleOfEquity100.0100.0100.00.00.00.00.0100.00.0100.0100.00.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

us-gaap:ProceedsFromLinesOfCredit

us-gaap:ProceedsFromLinesOfCredit


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-31
Value510472408305207186195594.235354.4493.651126.6111630377.8256.5916.324.2485.2481491005.885.1587.1175.068104.259.9649.2596.9268.4287.117
Percentage of ProceedsFromLinesOfCredit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ProceedsFromSaleMaturityAndCollectionsOfInvestments

us-gaap:ProceedsFromSaleMaturityAndCollectionsOfInvestments


Proceeds
Period End2021-06-302021-03-312020-12-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value0.08.0790.00.00.00.00.00.00.230.01.2862.2110.00.00.0
Percentage of ProceedsFromSaleMaturityAndCollectionsOfInvestments0.0100.00.00.00.00.00.00.0100.00.0100.0100.00.00.00.0

us-gaap:ProceedsFromSaleOfPropertyPlantAndEquipment

us-gaap:ProceedsFromSaleOfPropertyPlantAndEquipment


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302014-12-312013-12-312012-12-31
Value105000.060000.053000.0127000.058000.07000.0119000.0243000.0309000.00153000.0230000.0299000.0541000.03292000.0581000.0303000.03095000.0319000.0374000.0708000.005000000.0-5000000.005000.00
Percentage of ProceedsFromSaleOfPropertyPlantAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.00.0100.00.0

us-gaap:ProvisionForDoubtfulAccounts

us-gaap:ProvisionForDoubtfulAccounts


Provision
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-30
Value0.30.3-0.10.10.10.10.20.10.00.20.10.40.10.12928232721222019167.6820.4520.1740.6660.0480.006-0.0740.1690.481-0.3710.70.4890.3
Percentage of ProvisionForDoubtfulAccounts100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ProvisionForDoubtfulAccounts us-gaap:ProductOrService

opk:Rayaldee


Provision
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value119.8221113141214119.0866.8016.6814.642.8942.23
Percentage of ProvisionForDoubtfulAccounts3702.33274.0-11560.013868.014227.012736.07117.011995.00.03400.56681.01160.02894.02230.0

us-gaap:ProvisionForDoubtfulAccounts us-gaap:ProductOrService, us-gaap:ValuationAllowancesAndReservesType

opk:Rayaldee, opk:ChargebacksDiscountsRebatesAndFees


Provision
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value3.7243.8154.0424.2694.4684.8254.8013.9022.4632.2531.8691.6471.2270.961
Percentage of ProvisionForDoubtfulAccounts1241.31271.7-4042.04269.04468.04825.02400.53902.00.01126.51869.0411.81227.0961.0

opk:Rayaldee, opk:Governmental


Provision
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value7.0615.6947.1069.3359.0737.2088.0977.115.883.9114.1322.9931.5971.339
Percentage of ProvisionForDoubtfulAccounts2353.71898.0-7106.09335.09073.07208.04048.57110.00.01955.54132.0748.21597.01339.0

opk:Rayaldee, opk:SalesReturns


Provision
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value0.3220.3130.4120.2640.6860.7031.3360.9830.7430.6370.680.0
Percentage of ProvisionForDoubtfulAccounts107.3104.3-412.0264.0686.0703.0668.0983.00.0318.5680.00.0

us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty

us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty


Related
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-30
Value43000.0062000.0094000.00122000.037000.034000.061000.0
Percentage of RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty100.00.0100.00.0100.00.0100.0100.0100.0100.0

us-gaap:RepaymentsOfLinesOfCredit

us-gaap:RepaymentsOfLinesOfCredit


Repayments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-31
Value5104794003601941882007943356.2467.5118.50412127.1186.0087.5177.2779.56417.349150935.1734.8496.5467.2528.5865.985119.988106.9516.646
Percentage of RepaymentsOfLinesOfCredit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueConversionOfConvertibleSecurities

us-gaap:StockIssuedDuringPeriodValueConversionOfConvertibleSecurities


Stock
Period End2021-06-30
Value55
Percentage of StockIssuedDuringPeriodValueConversionOfConvertibleSecurities100.0

us-gaap:StockIssuedDuringPeriodValueConversionOfConvertibleSecurities us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stock
Period End2021-06-30
Value55
Percentage of StockIssuedDuringPeriodValueConversionOfConvertibleSecurities99.7

us-gaap:CommonStock


Stock
Period End2021-06-30
Value0.19
Percentage of StockIssuedDuringPeriodValueConversionOfConvertibleSecurities0.3

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised


Stock
Period End2021-06-302021-03-312020-12-312020-09-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302013-12-312013-09-302013-06-302013-03-31
Value0.1590.3080.0870.6690.00.00.00.0-0.0030.00.8560.318183.5070.0230.905
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised100.0100.0100.0100.00.00.00.00.0100.00.0100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stock
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302013-12-312013-09-302013-06-302013-03-31
Value0.1580.3070.0870.6670.00.00.0-0.0030.00.8540.316183.4750.0230.901
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised99.499.7100.099.70.00.00.0100.00.099.899.499.799.1100.099.6

us-gaap:CommonStock


Stock
Period End2021-06-302021-03-312020-12-312020-09-302018-12-312018-09-302018-06-302013-12-312013-09-302013-06-302013-03-31
Value0.0010.0010.00.0020.00.0020.0020.0560.0320.00.004
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised0.60.30.00.30.00.20.60.30.90.00.4

us-gaap:VariableInterestEntityOwnershipPercentage us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

us-gaap:VariableInterestEntityOwnershipPercentage

opk:Zebra


Variable
Period End2021-06-302021-03-31
Value029.0
Percentage of VariableInterestEntityOwnershipPercentage0.0100.0

us-gaap:VariableLeaseCost

us-gaap:VariableLeaseCost


Variable
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value700000.0700000.0700000.0700000.0800000.0800000.0800000.0900000.001700000.0
Percentage of VariableLeaseCost100.0100.0100.0100.0100.0100.0100.0100.00.0100.0

opk:AccruedClinicalTrialsCurrent

opk:AccruedClinicalTrialsCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value6.1166.5977.1125.9126.0797.548.1229.9759.9361110121114127.6069.1766.925.93510105.852.5054.3518.5349.628.6435.5242.6164.713.3423.5430.05
Percentage of AccruedClinicalTrialsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:AccruedCommitmentsandContingenciesCurrent

opk:AccruedCommitmentsandContingenciesCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-12-31
Value2317152238373815
Percentage of AccruedCommitmentsandContingenciesCurrent100.0100.0100.0100.0100.0100.0100.0100.0

opk:AccruedExpensePayorOverpaymentReimbursementLiability

opk:AccruedExpensePayorOverpaymentReimbursementLiability


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302017-12-31
Value9.5111421212327253035353230
Percentage of AccruedExpensePayorOverpaymentReimbursementLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets

opk:BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value17001700170018001800180018001900190019002000200020002000200021002100210021002100210022002200220012001100110011001100110011001100200
Percentage of BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsVested us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

opk:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsVested

opk:BioCardiaInc.


Class
Period End2020-09-30
Value37000.0
Percentage of ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsVested100.0

opk:DeferredTaxAssetsOperatingLeaseAsset

opk:DeferredTaxAssetsOperatingLeaseAsset


Deferred
Period End2020-12-312019-12-31
Value9.84210
Percentage of DeferredTaxAssetsOperatingLeaseAsset100.0100.0

opk:DeferredTaxLiabilitiesConvertibleDebt

opk:DeferredTaxLiabilitiesConvertibleDebt


Deferred
Period End2020-12-312019-12-312018-12-31
Value10120.0
Percentage of DeferredTaxLiabilitiesConvertibleDebt100.0100.00.0

opk:DeferredTaxLiabilitiesNetBeforeValuationAllowance

opk:DeferredTaxLiabilitiesNetBeforeValuationAllowance


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value-171.393-77.138-39.7236.66710718332
Percentage of DeferredTaxLiabilitiesNetBeforeValuationAllowance100.0100.0100.0100.0100.0100.0100.0

opk:EquityMethodInvestmentExcludingVariableInterestEntity

opk:EquityMethodInvestmentExcludingVariableInterestEntity


Equity
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value346000.0385000.0426000.0496000.0826000.0
Percentage of EquityMethodInvestmentExcludingVariableInterestEntity100.0100.0100.0100.0100.0

opk:EquityMethodInvestmentExcludingVariableInterestEntityUnderlyingEquityinNetAssets

opk:EquityMethodInvestmentExcludingVariableInterestEntityUnderlyingEquityinNetAssets


Equity
Period End2020-12-312019-12-31
Value2252000.09931000.0
Percentage of EquityMethodInvestmentExcludingVariableInterestEntityUnderlyingEquityinNetAssets100.0100.0

opk:EquityMethodInvestmentVariableInterestEntity

opk:EquityMethodInvestmentVariableInterestEntity


Equity
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value1030000.01057000.01060000.01036000.0894000.0
Percentage of EquityMethodInvestmentVariableInterestEntity100.0100.0100.0100.0100.0

opk:EquityMethodInvestmentVariableInterestEntityUnderlyingEquityInNetAssets

opk:EquityMethodInvestmentVariableInterestEntityUnderlyingEquityInNetAssets


Equity
Period End2021-03-312020-12-31
Value12000.09000.0
Percentage of EquityMethodInvestmentVariableInterestEntityUnderlyingEquityInNetAssets100.0100.0

opk:EquityMethodInvestmentVariableInterestEntityUnderlyingEquityinNetAssets

opk:EquityMethodInvestmentVariableInterestEntityUnderlyingEquityinNetAssets


Equity
Period End2020-12-31
Value9000.0
Percentage of EquityMethodInvestmentVariableInterestEntityUnderlyingEquityinNetAssets100.0

opk:EquitySecurityFVNIOwnershipPercent us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

opk:EquitySecurityFVNIOwnershipPercent

opk:BioCardiaInc.


Equity
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-31
Value1.01.02.00.020.030.050.050.050.050.050.05
Percentage of EquitySecurityFVNIOwnershipPercent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:ChromaDex


Equity
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-31
Value0.10.10.10.0010.0010.0010.0010.0010.00100
Percentage of EquitySecurityFVNIOwnershipPercent10.010.05.05.03.32.02.02.02.00.00.0

opk:ChromadexCorporation


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value0.10.10.10.10.0010.0010.0010.0010.0010.00100.00100
Percentage of EquitySecurityFVNIOwnershipPercent10.010.00.05.05.03.30.02.02.02.00.02.00.00.0

opk:EloxxPharmaceuticals


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value2.03.03.03.00.030.030.030.030.040.040.040.040.040.05
Percentage of EquitySecurityFVNIOwnershipPercent200.0300.00.0150.0150.0100.00.060.080.080.00.080.080.0100.0

opk:MabVaxTherapeuticsHoldingsInc.


Equity
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value1.01.01.00.010.010.010.010.010.010.020.020.020.02
Percentage of EquitySecurityFVNIOwnershipPercent100.00.050.050.033.30.020.020.020.00.040.040.040.0

opk:NIMS


Equity
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-31
Value1.01.01.00.010.010.010.010.010.010.010.01
Percentage of EquitySecurityFVNIOwnershipPercent100.0100.050.050.033.320.020.020.020.020.020.0

opk:PhioPharmaceuticals


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value0.010.010.010.010.00020.00030.0010.0020.0020.0020
Percentage of EquitySecurityFVNIOwnershipPercent1.01.00.00.51.01.00.04.04.04.00.0

opk:VBIVaccinesInc


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value1.01.01.01.00.030.040.040.040.070.070.07
Percentage of EquitySecurityFVNIOwnershipPercent100.0100.00.050.0150.0133.30.080.0140.0140.00.0

opk:FinanceLeaseLiabilityPaymentsDueAfterYearFour

opk:FinanceLeaseLiabilityPaymentsDueAfterYearFour


Finance
Period End2020-09-30
Value1000.0
Percentage of FinanceLeaseLiabilityPaymentsDueAfterYearFour100.0

opk:InProcessResearchandDevelopment

opk:InProcessResearchandDevelopment


In
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-12-31
Value590590590590590590590635
Percentage of InProcessResearchandDevelopment100.0100.0100.0100.0100.0100.0100.0100.0

opk:InventoryReceivedNotInvoicedCurrent

opk:InventoryReceivedNotInvoicedCurrent


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value335072844913
Percentage of InventoryReceivedNotInvoicedCurrent100.0100.0100.0100.0100.0100.0

opk:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour

opk:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour


Lessee
Period End2021-06-302021-03-312020-09-30
Value161617
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour100.0100.0100.0

opk:LineofCreditandNotesandLoansPayableCurrent

opk:LineofCreditandNotesandLoansPayableCurrent


Lineof
Period End2020-12-312019-12-312018-12-31
Value249.6195.851
Percentage of LineofCreditandNotesandLoansPayableCurrent100.0100.0100.0

opk:MortgagesAndOtherDebtsPayable

opk:MortgagesAndOtherDebtsPayable


Mortgages
Period End2020-12-312019-12-312013-06-302013-03-312012-12-31
Value3837000.03906000.03636000.03706000.05150000.0
Percentage of MortgagesAndOtherDebtsPayable100.0100.0100.0100.0100.0

opk:StockOptionandWarrantInvestments

opk:StockOptionandWarrantInvestments


Stock
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value68000.096000.074000.038000.0120000.0
Percentage of StockOptionandWarrantInvestments100.0100.0100.0100.0100.0

opk:TaxesRecoverableCurrent

opk:TaxesRecoverableCurrent


Taxes
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value9.2919.48131412131919181915202117181715161656526.0763.0763.0833.0741.9682.4171.2921.2981.2663.4582.9921.493
Percentage of TaxesRecoverableCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccountsAndOtherReceivablesNetCurrent

us-gaap:AccountsAndOtherReceivablesNetCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-312011-12-31
Value0.4920.3512.5020.7140.6610.6463.2620.1940.661-0.4572.3684.0142.0317.983.39812121213161315113.9951.1070.7330.6690.5650.6190.6051.9853.8180.8860.288
Percentage of AccountsAndOtherReceivablesNetCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccountsReceivableGrossCurrent

us-gaap:AccountsReceivableGrossCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value2683222882432151341361421501461451591541602312913062832562642622482191982920212224212122232121191612
Percentage of AccountsReceivableGrossCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccruedEmployeeBenefitsCurrent

us-gaap:AccruedEmployeeBenefitsCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value4046433734353334394245394646504648434333374029315.4566.4954.1275.6145.4055.4514.3996.4163.319
Percentage of AccruedEmployeeBenefitsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccruedProfessionalFeesCurrent

us-gaap:AccruedProfessionalFeesCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value3347000.04790000.04985000.05340000.04009000.0903000.01333000.02877000.03317000.06689000.07935000.03705000.01727000.02856000.02355000.02584000.04067000.04418000.04035000.02259000.01967000.0707000.01506000.01375000.01724000.01624000.01860000.0766000.01320000.01108000.0402000.07203000.0675000.0
Percentage of AccruedProfessionalFeesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AllowanceForDoubtfulAccountsReceivable us-gaap:ProductOrService

us-gaap:AllowanceForDoubtfulAccountsReceivable

opk:Rayaldee


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value12111115131211106.0884.8414.0432.4681.5771.3031.0180.0
Percentage of AllowanceForDoubtfulAccountsReceivable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

us-gaap:AllowanceForDoubtfulAccountsReceivable us-gaap:ProductOrService, us-gaap:ValuationAllowancesAndReservesType

opk:Rayaldee, opk:ChargebacksDiscountsRebatesAndFees


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value1.7011.6932.3322.1942.892.8633.1942.2921.4121.5071.3161.0380.7240.3890.2330.0
Percentage of AllowanceForDoubtfulAccountsReceivable13.514.919.913.821.123.127.122.623.231.132.642.145.929.922.90.0

opk:Rayaldee, opk:Governmental


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value7.5866.2095.8129.8126.9996.1995.8416.3133.8282.8462.091.370.7270.7320.3480.0
Percentage of AllowanceForDoubtfulAccountsReceivable60.254.549.561.651.050.049.662.162.958.851.755.546.156.234.20.0

opk:Rayaldee, opk:SalesReturns


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value3.3243.4873.5933.9353.833.3322.7511.5540.8480.4880.6370.060.1260.437
Percentage of AllowanceForDoubtfulAccountsReceivable26.430.630.624.727.926.923.315.313.910.115.82.48.042.9

us-gaap:AllowanceForDoubtfulAccountsReceivableCurrent

us-gaap:AllowanceForDoubtfulAccountsReceivableCurrent


Allowance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value2.52.52.12.01.61.71.91.82.12.01.81.71.4921.5276657554436414843259.1152.0651.6911.9061.4321.5471.5661.8851.1340.9080.6690.4740.3480.2840.44
Percentage of AllowanceForDoubtfulAccountsReceivableCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AssetsFairValueDisclosure

us-gaap:AssetsFairValueDisclosure


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value7.8928.9331412259.529199.39521282715
Percentage of AssetsFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AssetsFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel1


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value7.4668.8371412248.99189.12920272612
Percentage of AssetsFairValueDisclosure94.698.999.598.498.994.398.797.297.496.596.879.0

us-gaap:FairValueInputsLevel2


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value0.4260.0960.0740.2090.2660.5390.2530.2660.5521.0110.8763.333
Percentage of AssetsFairValueDisclosure5.41.10.51.61.15.71.32.82.63.53.221.0

us-gaap:AssetsHeldForSaleNotPartOfDisposalGroup

us-gaap:AssetsHeldForSaleNotPartOfDisposalGroup


Assets
Period End2021-06-30
Value33
Percentage of AssetsHeldForSaleNotPartOfDisposalGroup100.0

us-gaap:BusinessCombinationContingentConsiderationLiability

us-gaap:BusinessCombinationContingentConsiderationLiability


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value3.4743.5645.7119.9348.8239.72425292428274341405147454366555455747671717271716920
Percentage of BusinessCombinationContingentConsiderationLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:BusinessCombinationContingentConsiderationLiability us-gaap:BalanceSheetLocation

us-gaap:AccruedLiabilities


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value0.50.01.22.42.42.42.42.45.42.42.42.12.05.3112.05.10.30.35.230212228415227252425283.75.1
Percentage of BusinessCombinationContingentConsiderationLiability14.40.021.121.824.227.224.79.821.18.29.87.37.212.328.55.09.90.60.711.945.537.940.850.655.369.038.336.433.736.239.15.325.5

us-gaap:OtherNoncurrentLiabilities


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value3.03.64.58.67.66.47.32220272226253729384647443836343227332344454845436514
Percentage of BusinessCombinationContingentConsiderationLiability86.4101.078.978.176.572.575.390.279.092.090.293.192.887.971.595.090.199.299.388.154.562.159.449.444.731.061.763.866.363.860.994.774.5

us-gaap:BusinessCombinationContingentConsiderationLiability us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel3


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-06-302019-03-312018-12-31
Value3.4743.5645.695119.9348.8239.683252924
Percentage of BusinessCombinationContingentConsiderationLiability100.0100.099.9100.0100.0100.099.8100.0100.099.7

us-gaap:BusinessCombinationContingentConsiderationLiabilityCurrent

us-gaap:BusinessCombinationContingentConsiderationLiabilityCurrent


Business
Period End2021-06-302020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value0.4871.1882.3742.3752.3752.3752.3755.3872.3752.3752.0922.0425.254112.0115.0810.3030.2595.21130212228415227
Percentage of BusinessCombinationContingentConsiderationLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:BusinessCombinationContingentConsiderationLiabilityNoncurrent

us-gaap:BusinessCombinationContingentConsiderationLiabilityNoncurrent


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312014-12-31
Value2.9873.5644.5078.6437.5596.4487.3082220262226253729384647443836343244
Percentage of BusinessCombinationContingentConsiderationLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights

opk:BioCardiaInc.


Class
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-31
Value47000.047000.047000.047000.047000.047000.047000.047000.047000.0400000.0400000.0400000.0400000.0400000.0400000.05000000.05000000.05000000.05000000.0
Percentage of ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:Cocrystal


Class
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312014-12-31
Value33000.033000.033000.033000.033000.033000.033000.033000.033000.033000.033000.033000.033000.01000000.01000000.01000000.01000000.01000000.01000000.01000000.01000000.01000000.01000000.01000000.0
Percentage of ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights70.270.270.270.270.270.270.270.270.28.28.28.28.2250.0250.020.020.020.020.00.00.00.00.00.0

opk:XeneticBiosciencesInc.


Class
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-31
Value40000.040000.040000.040000.040000.040000.040000.040000.040000.0500000.0500000.0500000.0500000.0500000.0500000.0500000.0500000.0500000.0500000.0
Percentage of ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights85.185.185.185.185.185.185.185.185.1125.0125.0125.0125.0125.0125.010.010.010.010.0

us-gaap:ContractWithCustomerLiability

us-gaap:ContractWithCustomerLiability


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value8.9521516171712213454739189109125140
Percentage of ContractWithCustomerLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ContractWithCustomerLiabilityNoncurrent

us-gaap:ContractWithCustomerLiabilityNoncurrent


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value0.5520.5570.5952.9511.172.5713.2573.6657.7082728476378
Percentage of ContractWithCustomerLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ConvertibleLongTermNotesPayable

us-gaap:ConvertibleLongTermNotesPayable


Convertible
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302012-12-31
Value18322422121921621321120820620357565555292834394351454949441091061311141162242112081880.0
Percentage of ConvertibleLongTermNotesPayable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

us-gaap:DebtInstrumentCarryingAmount us-gaap:LongtermDebtType

us-gaap:DebtInstrumentCarryingAmount

us-gaap:SeniorNotes


Debt
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312015-12-31
Value1442002002002002002002002002003131313131313132
Percentage of DebtInstrumentCarryingAmount100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DebtInstrumentUnamortizedDiscount us-gaap:LongtermDebtType

us-gaap:DebtInstrumentUnamortizedDiscount

us-gaap:SeniorNotes


Debt
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312015-12-31
Value253739414345464850510.2880.8791.4562.0182.5653.0984.6126.525
Percentage of DebtInstrumentUnamortizedDiscount100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DebtWeightedAverageInterestRate us-gaap:BusinessAcquisition

us-gaap:DebtWeightedAverageInterestRate

opk:OPKOHealthEurope


Debt
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value2.72.82.92.80.0260.0270.0270.0270.0270.0320.0210.0280.030.0250.030.0290.0310.030.0320.0290.0340.0340.0430.0330.0320.0320.0340.039
Percentage of DebtWeightedAverageInterestRate100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DebtWeightedAverageInterestRate us-gaap:LongtermDebtType

us-gaap:LineOfCredit


Debt
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-31
Value5.45.54.95.30.0420.0410.040.0440.0450.0430.0470.0470.0470.0410.0420.0450.0420.0420.0470.0480.0460.0460.0430.0460.0570.0590.0610.060.0580.0590.0770.0740.0640.0650.065
Percentage of DebtWeightedAverageInterestRate200.0196.4169.0189.3161.5151.9148.1163.0166.7134.4223.8167.9156.7164.0140.0155.2135.5140.0146.9165.5135.3135.3100.0139.4178.1184.4179.40.00.00.0197.40.00.00.00.0

us-gaap:DeferredFinanceCostsNet us-gaap:LongtermDebtType

us-gaap:DeferredFinanceCostsNet

us-gaap:SeniorNotes


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312015-12-31
Value2802000.04092000.04300000.04506000.04705000.04898000.05086000.05271000.05451000.05623000.0014000.051000.088000.0125000.0162000.0273000.0426000.0
Percentage of DeferredFinanceCostsNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredIncomeTaxLiabilities


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value982592562883694051811842918
Percentage of DeferredIncomeTaxLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetIntraEntityTransferAssetOtherThanInventory

us-gaap:DeferredTaxAssetIntraEntityTransferAssetOtherThanInventory


Deferred
Period End2020-12-31
Value148
Percentage of DeferredTaxAssetIntraEntityTransferAssetOtherThanInventory100.0

us-gaap:DeferredTaxAssetsEquityMethodInvestments

us-gaap:DeferredTaxAssetsEquityMethodInvestments


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Value1313128.4547.0114.428.0384.7561.234
Percentage of DeferredTaxAssetsEquityMethodInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsGross


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value269336296282262221149
Percentage of DeferredTaxAssetsGross100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value301000.01560000.02893000.04038000.03246000.05138000.09244000.04746000.02162000.02884000.0
Percentage of DeferredTaxAssetsInProcessResearchAndDevelopment100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsDomestic

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsDomestic


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value9012110179767163435040
Percentage of DeferredTaxAssetsOperatingLossCarryforwardsDomestic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsForeign

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsForeign


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value17323435323325203.4272.142
Percentage of DeferredTaxAssetsOperatingLossCarryforwardsForeign100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value546459463614126.9876.7747.254
Percentage of DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOtherTaxCarryforwards

us-gaap:DeferredTaxAssetsOtherTaxCarryforwards


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value6.3938.39511177.7957.1044.7022.9044.0942.991
Percentage of DeferredTaxAssetsOtherTaxCarryforwards100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsForeign

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsForeign


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-31
Value9.8199.9091011100.0
Percentage of DeferredTaxAssetsTaxCreditCarryforwardsForeign100.0100.0100.0100.0100.00.0

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value22222120207.3886.0774.8764.2043.688
Percentage of DeferredTaxAssetsTaxCreditCarryforwardsResearch100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost

us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value26303028362418136.3265.283
Percentage of DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value14176.2945.7198.3067.0861.764
Percentage of DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value0.310.4450.4142014380.0
Percentage of DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts100.0100.0100.0100.0100.0100.00.0

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsDeferredRent

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsDeferredRent


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value861000.01064000.01370000.02205000.03233000.07022000.01764000.01936000.0
Percentage of DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsDeferredRent100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross

us-gaap:DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-31
Value2473000.02478000.02447000.02406000.04792000.00
Percentage of DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross100.0100.0100.0100.0100.00.0

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value732302502803543861771792518
Percentage of DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxLiabilitiesLeasingArrangements

us-gaap:DeferredTaxLiabilitiesLeasingArrangements


Deferred
Period End2020-12-312019-12-31
Value9.84210
Percentage of DeferredTaxLiabilitiesLeasingArrangements100.0100.0

us-gaap:DeferredTaxLiabilitiesOther

us-gaap:DeferredTaxLiabilitiesOther


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value2082000.02130000.02272000.02325000.02121000.01538000.04305000.04996000.03277000.0106000.0
Percentage of DeferredTaxLiabilitiesOther100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxLiabilitiesPropertyPlantAndEquipment

us-gaap:DeferredTaxLiabilitiesPropertyPlantAndEquipment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value2.7363.9763.4865.57213170.0
Percentage of DeferredTaxLiabilitiesPropertyPlantAndEquipment100.0100.0100.0100.0100.0100.00.0

us-gaap:DerivativeAssets

us-gaap:DerivativeAssets


Derivative
Period End2020-12-31
Value74000.0
Percentage of DerivativeAssets100.0

us-gaap:DerivativeAssets us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel2


Derivative
Period End2020-12-31
Value74000.0
Percentage of DerivativeAssets100.0

us-gaap:DerivativeAssets us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:FinancialInstrument

us-gaap:FairValueInputsLevel2, us-gaap:EquitySecurities


Derivative
Period End2021-06-30
Value68000.0
Percentage of DerivativeAssets0.0

us-gaap:FairValueInputsLevel2, us-gaap:ForwardContracts


Derivative
Period End2021-06-302020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value358000.0171000.0215000.0481000.0133000.0146000.064000.021000.0
Percentage of DerivativeAssets0.00.00.00.00.00.00.00.0

us-gaap:DerivativeAssets us-gaap:FinancialInstrument

us-gaap:EquitySecurities


Derivative
Period End2021-06-30
Value68000.0
Percentage of DerivativeAssets0.0

us-gaap:ForwardContracts


Derivative
Period End2021-06-302020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value358000.0171000.0215000.0481000.0133000.0146000.064000.021000.0
Percentage of DerivativeAssets0.00.00.00.00.00.00.00.0

us-gaap:DerivativeFairValueOfDerivativeAsset

us-gaap:DerivativeFairValueOfDerivativeAsset


Derivative
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value96000.074000.038000.051000.058000.0120000.0120000.0488000.0880000.0855000.0
Percentage of DerivativeFairValueOfDerivativeAsset100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DerivativeFairValueOfDerivativeAsset us-gaap:BalanceSheetLocation, us-gaap:DerivativeInstrumentRisk, us-gaap:HedgingDesignation

opk:PrepaidExpensesandOtherCurrentAssetsAccruedExpenses, us-gaap:ForwardContracts, us-gaap:Nondesignated


Derivative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value358000.0206000.0-1040000.0171000.0215000.0481000.0133000.0146000.064000.0131000.021000.0
Percentage of DerivativeFairValueOfDerivativeAsset0.0214.6-1405.4450.0421.6829.3110.8121.713.114.92.5

us-gaap:Investments, us-gaap:StockOption, us-gaap:Nondesignated


Derivative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value68000.096000.074000.038000.051000.058000.0120000.0120000.0488000.0880000.0855000.01511000.01799000.05004000.03333000.02020000.03537000.03072000.04017000.02113000.0888000.04615000.05338000.05543000.09969000.09723000.06314000.05703000.05980000.06797000.05988000.01618000.01872000.0
Percentage of DerivativeFairValueOfDerivativeAsset0.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:DerivativeFairValueOfDerivativeAsset us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel2


Derivative
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value96000.074000.038000.051000.058000.0120000.0120000.0488000.0880000.0855000.0
Percentage of DerivativeFairValueOfDerivativeAsset100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DerivativeFairValueOfDerivativeLiability us-gaap:BalanceSheetLocation, us-gaap:DerivativeInstrumentRisk, us-gaap:HedgingDesignation

us-gaap:DerivativeFairValueOfDerivativeLiability

opk:LongtermDebtCurrentMaturities, us-gaap:ForwardContracts, us-gaap:Nondesignated


Derivative
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value-1.040.1330.021-0.3170.0390.0090.0650.1150.0140.0362.9143.6242.4361.5853.8991.294
Percentage of DerivativeFairValueOfDerivativeLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DerivativeLiabilities us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:FinancialInstrument

us-gaap:DerivativeLiabilities

us-gaap:FairValueInputsLevel2, us-gaap:ForwardContracts


Derivative
Period End2021-03-312020-12-31
Value206000.01040000.0
Percentage of DerivativeLiabilities100.0100.0

us-gaap:DerivativeLiabilities us-gaap:FinancialInstrument

us-gaap:ForwardContracts


Derivative
Period End2021-03-312020-12-31
Value206000.01040000.0
Percentage of DerivativeLiabilities100.0100.0

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized


Employee
Period End2020-12-31
Value18
Percentage of EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized100.0

us-gaap:EquityMethodInvestmentOwnershipPercentage us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

us-gaap:EquityMethodInvestmentOwnershipPercentage

opk:BioCardiaInc.


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value1.01.02.02.00.020.030.030.050.050.050.050.050.050.050.050.050.050.05
Percentage of EquityMethodInvestmentOwnershipPercentage100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

opk:Cocrystal


Equity
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-312015-09-302015-06-302015-03-31
Value3.04.05.00.050.050.080.080.080.090.090.090.090.090.080.080.080.080.080.080.08
Percentage of EquityMethodInvestmentOwnershipPercentage300.0400.0250.0250.0166.7160.0160.0160.0180.0180.0180.0180.0180.0160.00.00.00.00.00.00.0

opk:CocrystalPharmaInc.


Equity
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-31
Value4.00.070.090.090.080.08
Percentage of EquityMethodInvestmentOwnershipPercentage200.0233.3180.0180.00.00.0

opk:InCellDxInc


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-31
Value29.029.029.029.00.290.290.290.290.290.290.290.290.290.290.280.270.270.270.270.27
Percentage of EquityMethodInvestmentOwnershipPercentage2900.02900.01450.01450.01450.0966.7966.7580.0580.0580.0580.0580.0580.0580.0560.0540.0540.00.00.00.0

opk:NIMS


Equity
Period End2020-12-312019-12-312018-12-312017-12-31
Value1.00.010.010.01
Percentage of EquityMethodInvestmentOwnershipPercentage50.033.320.020.0

opk:Neovasc


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-31
Value1.01.01.02.00.020.030.040.040.050.050.040.060.060.010.050.040.040.040.040.040.040.040.040.050.050.05
Percentage of EquityMethodInvestmentOwnershipPercentage100.0100.050.0100.0100.0100.0133.380.0100.0100.080.0120.0120.020.0100.080.080.080.00.00.00.00.00.00.00.00.0

opk:NonInvasiveMonitoringSystemsInc.


Equity
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-31
Value1.01.01.00.010.010.010.010.010.010.010.010.010.010.010.010.010.01
Percentage of EquityMethodInvestmentOwnershipPercentage100.0100.050.050.033.320.020.020.020.020.020.020.020.020.00.00.00.0

opk:Pharmsynthez


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-312013-04-30
Value9.09.09.09.00.090.090.090.090.090.090.090.090.090.090.090.090.090.170.170.179.0
Percentage of EquityMethodInvestmentOwnershipPercentage900.0900.0450.0450.0450.0300.0300.0180.0180.0180.0180.0180.0180.0180.0180.0180.0180.00.00.00.00.0

opk:XeneticBiosciencesInc.


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-09-30
Value2.02.03.03.00.030.030.030.050.040.040.040.040.050.040.04
Percentage of EquityMethodInvestmentOwnershipPercentage200.0200.0150.0150.0150.0100.0100.0100.080.080.080.080.0100.080.080.0

opk:Zebra


Equity
Period End2020-12-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-31
Value29.00.290.290.290.290.290.290.290.290.290.290.290.290.290.290.280.290.290.290.290.280.280.27
Percentage of EquityMethodInvestmentOwnershipPercentage1450.01450.0966.7966.7580.0580.0580.0580.0580.0580.0580.0580.0580.0580.0580.00.00.00.00.00.00.00.00.0

us-gaap:EquityMethodInvestmentOwnershipPercentage us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName, us-gaap:InvestmentsByConsolidatedAndNonconsolidatedEntities

opk:DetectGenomix, us-gaap:VariableInterestEntityNotPrimaryBeneficiary


Equity
Period End2020-09-30
Value49.0
Percentage of EquityMethodInvestmentOwnershipPercentage2450.0

opk:Zebra, us-gaap:VariableInterestEntityNotPrimaryBeneficiary


Equity
Period End2020-09-30
Value29.0
Percentage of EquityMethodInvestmentOwnershipPercentage1450.0

us-gaap:EquityMethodInvestmentQuotedMarketValue

us-gaap:EquityMethodInvestmentQuotedMarketValue


Equity
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value7100000.07600000.07500000.06200000.06000000.0
Percentage of EquityMethodInvestmentQuotedMarketValue100.0100.0100.0100.0100.0

us-gaap:EquityMethodInvestmentUnderlyingEquityInNetAssets

us-gaap:EquityMethodInvestmentUnderlyingEquityInNetAssets


Equity
Period End2021-06-302021-03-312020-12-312020-09-30
Value2242000.02479000.02252000.02374000.0
Percentage of EquityMethodInvestmentUnderlyingEquityInNetAssets100.0100.0100.0100.0

us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount

us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount


Equity
Period End2021-06-302021-03-312020-12-312020-09-302019-12-31
Value35000.035000.035000.035000.036000.0
Percentage of EquitySecuritiesWithoutReadilyDeterminableFairValueAmount100.0100.0100.0100.0100.0

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue us-gaap:FairValueByLiabilityClass

us-gaap:FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue

opk:ContingentConsideration


Fair
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-312011-12-31
Value3.4743.5645.694119.9348.8239.683242529242827434140514745436655545574767171727171692018
Percentage of FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiability


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value4643000.04793000.05258000.04881000.0
Percentage of FinanceLeaseLiability100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityCurrent

us-gaap:FinanceLeaseLiabilityCurrent


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2084000.02287000.02453000.02343000.02435000.02598000.02743000.02983000.03031000.03077000.0
Percentage of FinanceLeaseLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityNoncurrent

us-gaap:FinanceLeaseLiabilityNoncurrent


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2559000.02506000.02805000.02538000.02960000.03489000.04046000.04325000.04650000.04981000.0
Percentage of FinanceLeaseLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDue


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value4891000.04999000.05445000.05089000.0
Percentage of FinanceLeaseLiabilityPaymentsDue100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueNextTwelveMonths


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value1648000.01525000.02527000.02242000.0
Percentage of FinanceLeaseLiabilityPaymentsDueNextTwelveMonths100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueYearFive

us-gaap:FinanceLeaseLiabilityPaymentsDueYearFive


Finance
Period End2020-12-31
Value72000.0
Percentage of FinanceLeaseLiabilityPaymentsDueYearFive100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueYearFour

us-gaap:FinanceLeaseLiabilityPaymentsDueYearFour


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value215000.0113000.0511000.0277000.0
Percentage of FinanceLeaseLiabilityPaymentsDueYearFour100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueYearThree


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value697000.0571000.0860000.0620000.0
Percentage of FinanceLeaseLiabilityPaymentsDueYearThree100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueYearTwo

us-gaap:FinanceLeaseLiabilityPaymentsDueYearTwo


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value1038000.0921000.01475000.01218000.0
Percentage of FinanceLeaseLiabilityPaymentsDueYearTwo100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear

us-gaap:FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear


Finance
Period End2021-06-302021-03-312020-09-30
Value1293000.01869000.0731000.0
Percentage of FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear100.0100.0100.0

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount


Finance
Period End2021-06-302021-03-312020-12-312020-09-30
Value248000.0206000.0187000.0208000.0
Percentage of FinanceLeaseLiabilityUndiscountedExcessAmount100.0100.0100.0100.0

us-gaap:FinanceLeaseRightOfUseAsset

us-gaap:FinanceLeaseRightOfUseAsset


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value4643000.04793000.05258000.04880000.05395000.06087000.06789000.0
Percentage of FinanceLeaseRightOfUseAsset100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value5.34.33.64.30.0390.0360.03
Percentage of FinanceLeaseWeightedAverageDiscountRatePercent100.0100.0100.0100.0100.0100.0100.0

us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization

us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value378365356342327311298306291274258248231216198181160141123105887259453835333129262421191614119.4125.335
Percentage of FiniteLivedIntangibleAssetsAccumulatedAmortization100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths


Finite
Period End2020-12-31
Value50
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive


Finite
Period End2020-12-31
Value42
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearFive100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour


Finite
Period End2020-12-31
Value44
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearFour100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree


Finite
Period End2020-12-31
Value47
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearThree100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo


Finite
Period End2020-12-31
Value50
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo100.0

us-gaap:FiniteLivedIntangibleAssetsGross us-gaap:FiniteLivedIntangibleAssetsByMajorClass

us-gaap:FiniteLivedIntangibleAssetsGross

opk:ProductRegistrations


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value7.8037.8818.0257.437.1096.8767.5787.5548.0167.9547.8619.5699.6941010108.2338.047.6417.9117.8367.7977.5127.6428.0888.2248.7638.9419.6879.7319.6929.8619.637
Percentage of FiniteLivedIntangibleAssetsGross100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:CustomerRelationships


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value447447448446445444445444446445446446447449448447446444443445450451449451552122222222222223
Percentage of FiniteLivedIntangibleAssetsGross5734.85673.15591.96013.46261.76462.05877.65884.65565.75603.05677.34670.94613.44245.94280.14123.65421.75523.55805.05634.55752.85790.55990.05902.0689.3266.8252.3247.8232.4231.5234.5232.1239.6

us-gaap:LicensingAgreements


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302014-12-31
Value5.7665.7665.7665.7665.7665.7665.7665.7665.7665.7665.766101010102323232323232323250.572
Percentage of FiniteLivedIntangibleAssetsGross73.973.271.977.681.183.976.176.371.972.573.3106.9105.797.498.4216.6285.4292.5307.6297.1300.0301.0311.9332.46.5

us-gaap:NoncompeteAgreements


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value1616161616161616161616161616161616161616168.6198.6128.6188.628.6188.6398.6528.6698.678.6718.6678.662
Percentage of FiniteLivedIntangibleAssetsGross209.3207.2203.5219.7229.5237.3215.3216.0203.6205.2207.6171.1168.8154.7156.3150.8198.8203.4214.0206.8208.8110.5114.6112.8106.6104.898.696.889.589.189.587.989.9

us-gaap:OtherIntangibleAssets


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value6.3516.2886.5136.2966.16.0076.0945.9745.5865.5335.6135.6685.6965.925.7995.7425.6045.3455.2894.434.3944.4815.6114.8890.9911.0791.1311.191.1732.5191.1770.367
Percentage of FiniteLivedIntangibleAssetsGross81.479.881.284.785.887.480.479.169.769.671.459.258.855.955.452.968.166.569.256.056.157.574.5148.460.412.112.312.612.312.126.011.93.8

us-gaap:TechnologyBasedIntangibleAssets


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value290288296296296296296340340340340340340341340340340340340339339151151151525252525353515252
Percentage of FiniteLivedIntangibleAssetsGross3724.03657.23696.23989.64167.34307.33909.34508.14250.34282.74334.43561.43515.73221.73254.63139.64138.54234.54454.94289.44330.11947.12019.61986.3646.5634.3599.2589.4547.2544.9533.0536.9548.0

us-gaap:TradeNames


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-31
Value4949494949494949505050505050505050505050505050503.4113.4173.4833.5093.6153.6213.6693.7023.746
Percentage of FiniteLivedIntangibleAssetsGross638.3632.0620.8670.1700.1723.7657.0659.0629.0633.8641.2527.6520.9477.8482.6465.3613.1627.6660.1638.0644.1647.2671.1659.942.241.539.739.237.337.237.937.538.9

us-gaap:GoodwillImpairedAccumulatedImpairmentLoss

us-gaap:GoodwillImpairedAccumulatedImpairmentLoss


Goodwill
Period End2021-01-012020-01-012019-01-01
Value383811
Percentage of GoodwillImpairedAccumulatedImpairmentLoss100.0100.0100.0

us-gaap:InventoryRawMaterials

us-gaap:InventoryRawMaterials


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value6409000.05966000.05784000.06343000.05826000.04591000.04586000.04264000.04741000.04729000.04259000.05106000.05800000.06892000.07467000.06984000.06352000.05500000.04686000.06014000.05453000.05051000.03848000.05472000.05782000.03638000.04116000.04859000.04948000.05355000.04132000.04426000.04721000.05152000.04923000.04513000.02598000.02287000.0
Percentage of InventoryRawMaterials100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InventoryValuationReserves

us-gaap:InventoryValuationReserves


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value4844000.04897000.02321000.03681000.03129000.01893000.02537000.02553000.03033000.03460000.02956000.02398000.04726000.05857000.06565000.06445000.05977000.06029000.0945000.01147000.01313000.01230000.01051000.0794000.0712000.0554000.0639000.0592000.0579000.0482000.0777000.01135000.01365000.02277000.01313000.01408000.0599000.0325000.0
Percentage of InventoryValuationReserves100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InventoryWorkInProcess

us-gaap:InventoryWorkInProcess


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value3449000.04706000.05268000.06425000.04711000.04260000.03238000.03239000.03096000.02851000.02473000.03018000.03910000.04505000.05873000.04087000.04983000.04368000.03896000.01596000.01137000.01205000.01215000.01045000.01619000.0891000.01011000.01040000.01510000.01112000.01350000.01450000.01253000.0970000.0688000.0633000.0401000.0277000.0
Percentage of InventoryWorkInProcess100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value10109.1767.737
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear

us-gaap:LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear


Lessee
Period End2021-06-302021-03-312020-09-30
Value4535000.07492000.03154000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear100.0100.0100.0

us-gaap:LiabilitiesFairValueDisclosure

us-gaap:LiabilitiesFairValueDisclosure


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value3.4743.776.735119.9348.8239.6832425292441
Percentage of LiabilitiesFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:LiabilitiesFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel2


Liabilities
Period End2021-03-312020-12-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value0.2061.040.00.00.00.00.00.00.00.317
Percentage of LiabilitiesFairValueDisclosure5.515.40.00.00.00.00.00.00.00.8

us-gaap:FairValueInputsLevel3


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value3.4743.5645.695119.9348.8239.6832425292441
Percentage of LiabilitiesFairValueDisclosure100.094.584.6100.0100.0100.0100.0100.0100.0100.0100.099.2

us-gaap:LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent

us-gaap:LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent


Liabilities
Period End2021-06-302012-09-302012-06-302012-03-312011-12-312011-09-302010-12-31
Value233000.01000.087000.0245000.0174000.01460000.03060000.0
Percentage of LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent100.0100.0100.0100.0100.0100.0100.0

us-gaap:LineOfCredit

us-gaap:LineOfCredit


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value16162210635052567411010810910911011410580474747478282778.3587.8937.658
Percentage of LineOfCredit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:LineOfCredit us-gaap:LineOfCreditFacility

opk:BCIBank


Line
Period End2021-06-30
Value2.645
Percentage of LineOfCredit16.3

opk:BankOfChile


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value0.861.7321.4940.0760.8650.950.8511.0591.3470.8440.4320.4890.5021.091.5982.6872.4861.5661.6191.9352.4931.8532.3132.1011.5720.8051.41
Percentage of LineOfCredit5.310.86.50.71.41.91.61.91.80.80.40.40.51.01.42.53.13.33.44.15.22.22.82.718.810.218.4

opk:BiceBank


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value0.9190.311.1662.0191.0190.8961.4290.8540.2210.7470.8180.5430.7980.8631.8191.721.1510.5921.5381.1150.3141.5661.5021.5911.0881.341.249
Percentage of LineOfCredit5.71.95.118.41.61.82.71.50.30.70.80.50.70.81.61.61.41.23.32.40.71.91.82.113.017.016.3

opk:Corpbanca


Line
Period End2020-12-31
Value3.641
Percentage of LineOfCredit15.9

opk:Corpbanca1


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-31
Value3.2653.6833.6413.293.9171.0170.00.00.00.00.00.00.0180.1820.3180.160.0
Percentage of LineOfCredit20.222.915.929.96.22.00.00.00.00.00.00.00.00.40.70.20.0

opk:EstadoBank


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value2.1612.4252.1271.451.9742.1091.3650.8881.1640.7640.3081.020.7570.932.1112.5591.8522.011.871.4311.3531.6132.212.1122.0391.8111.87
Percentage of LineOfCredit13.315.19.313.23.14.22.61.61.60.70.30.90.70.81.82.42.34.24.03.02.81.92.72.724.422.924.4

opk:ItauBank


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value2.8872.542.3530.5490.530.5650.4721.0271.2870.5940.2321.2021.1790.2750.4460.3740.280.3950.4191.021.00.5380.2820.981.1710.9180.965
Percentage of LineOfCredit17.815.810.35.00.81.10.91.81.70.50.21.11.10.20.40.40.30.80.92.22.10.60.31.314.011.612.6

opk:JPMorganChase


Line
Period End2020-12-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312014-12-31
Value7.057513944506810510510510510510493693938383872720.0
Percentage of LineOfCredit30.781.078.385.990.292.695.796.895.796.494.790.888.186.382.482.081.480.087.487.20.0

opk:SabadellBank


Line
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value3.0251.9430.8521.9881.1961.3450.0
Percentage of LineOfCredit13.23.70.81.72.51.60.0

opk:SantanderBank


Line
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302014-12-31
Value0.6632.9513.0251.7832.6483.1860.01.0440.5610.5240.010.7080.2621.2430.02.1332.6912.2661.1961.3081.3251.6261.3450.750.0
Percentage of LineOfCredit4.118.313.216.24.26.30.01.90.80.50.00.60.21.10.02.03.34.82.52.82.82.01.61.00.0

opk:Scotiabank


Line
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312014-12-31
Value1.8911.8291.8261.0951.6640.6680.3070.0080.0810.0020.00.0090.3780.3840.9861.040.8640.7890.8021.2871.1140.9390.0
Percentage of LineOfCredit11.88.016.61.73.31.30.50.00.10.00.00.00.30.30.91.31.81.71.72.71.31.10.0

opk:Security


Line
Period End2021-06-302021-03-312020-12-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value2.7970.5610.2620.00.4890.5880.2940.2960.00.00.0270.0980.5730.5010.00.00.00.00.00.1450.3460.3050.3340.361
Percentage of LineOfCredit17.33.51.10.01.01.10.50.40.00.00.00.10.50.40.00.00.00.00.00.20.43.64.24.7

us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity us-gaap:CreditFacility, us-gaap:DebtInstrument, us-gaap:LongtermDebtType

us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity

us-gaap:RevolvingCreditFacility, opk:NewCreditAgreement, us-gaap:LineOfCredit


Line
Period End2021-06-302021-03-312020-12-312020-09-30
Value64645764
Percentage of LineOfCreditFacilityRemainingBorrowingCapacity100.0100.0100.0100.0

us-gaap:LinesOfCreditCurrent

us-gaap:LinesOfCreditCurrent


Lines
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312013-06-302013-03-312012-12-312012-09-302012-06-302011-12-312011-09-302011-06-302010-12-31
Value1717241214129.6197.187111125.8516.3536.4656.9711113161717148.757121414
Percentage of LinesOfCreditCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:LongTermDebtPercentageBearingVariableInterestRate us-gaap:Range, us-gaap:BusinessAcquisition

us-gaap:LongTermDebtPercentageBearingVariableInterestRate

srt:Maximum, opk:OPKOHealthEurope


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value3.83.83.83.80.0380.0380.0380.0380.0380.0550.0630.0630.063
Percentage of LongTermDebtPercentageBearingVariableInterestRate100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

srt:Minimum, opk:OPKOHealthEurope


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value0.70.70.70.70.0070.0070.010.0130.0130.0130.010.0180.018
Percentage of LongTermDebtPercentageBearingVariableInterestRate18.418.418.418.418.418.426.334.234.223.615.928.628.6

us-gaap:LongTermLineOfCredit us-gaap:CreditFacility, us-gaap:DebtInstrument, us-gaap:LongtermDebtType

us-gaap:LongTermLineOfCredit

us-gaap:RevolvingCreditFacility, opk:NewCreditAgreement, us-gaap:LineOfCredit


Long
Period End2020-12-312020-06-302020-03-312019-12-312019-09-302019-06-30
Value7.15139445065
Percentage of LongTermLineOfCredit100.0100.0100.0100.0100.0100.0

us-gaap:NotesPayableFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:LongtermDebtType

us-gaap:NotesPayableFairValueDisclosure

us-gaap:FairValueInputsLevel2, us-gaap:ConvertibleNotesPayable


Notes
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312017-09-30
Value1882682542470.00.0
Percentage of NotesPayableFairValueDisclosure100.0100.0100.0100.00.00.0

us-gaap:NotesPayableFairValueDisclosure us-gaap:FairValueByMeasurementBasis, us-gaap:LongtermDebtType

us-gaap:CarryingReportedAmountFairValueDisclosure, us-gaap:ConvertibleNotesPayable


Notes
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-30
Value116158156154148292828272727262625253538656463112110109
Percentage of NotesPayableFairValueDisclosure61.458.961.562.30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:NotesPayableFairValueDisclosure us-gaap:LongtermDebtType

us-gaap:ConvertibleNotesPayable


Notes
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value18826825424715832372929282726252422343863
Percentage of NotesPayableFairValueDisclosure100.0100.0100.0100.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value5.75.75.86.40.0640.0630.063
Percentage of OperatingLeaseWeightedAverageDiscountRatePercent100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingLossCarryforwards us-gaap:IncomeTaxAuthority

us-gaap:OperatingLossCarryforwards

us-gaap:DomesticCountry


Operating
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value538698606488409362294223
Percentage of OperatingLossCarryforwards100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ForeignCountry


Operating
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Value78139152146186126977613
Percentage of OperatingLossCarryforwards14.620.025.130.145.634.932.934.30.0

us-gaap:StateAndLocalJurisdiction


Operating
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Value729873801602406199262200179
Percentage of OperatingLossCarryforwards135.5125.1132.2123.499.355.289.089.50.0

us-gaap:OperatingLossCarryforwardsValuationAllowance

us-gaap:OperatingLossCarryforwardsValuationAllowance


Operating
Period End2020-12-31
Value47
Percentage of OperatingLossCarryforwardsValuationAllowance100.0

us-gaap:OtherInventorySupplies

us-gaap:OtherInventorySupplies


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302014-12-31
Value90114867241282323222123222422211921232322222022210.279
Percentage of OtherInventorySupplies100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherLiabilitiesAndDeferredRevenueNoncurrent

us-gaap:OtherLiabilitiesAndDeferredRevenueNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312012-09-302012-06-302011-12-31
Value141625262423252729343317221817172221219.531141413183.7533.3683.5563.6582.020.6791.5091.0062.1911.5750.380.4530.4510.578
Percentage of OtherLiabilitiesAndDeferredRevenueNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PrepaidInsurance

us-gaap:PrepaidInsurance


Prepaid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-312011-12-31
Value7374000.01458000.03803000.06635000.06274000.06143000.03486000.05160000.03878000.02847000.03436000.04695000.03259000.02179000.03532000.03276000.02162000.02117000.03688000.05520000.02144000.01736000.02206000.0594000.0613000.01041000.0968000.0944000.01113000.0902000.0892000.0843000.0301000.0176000.0
Percentage of PrepaidInsurance100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization


Property
Period End2020-12-312019-12-31
Value164136
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization


Property
Period End2021-06-302020-12-312019-12-31
Value106140127
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization100.0100.0100.0

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization us-gaap:StatementGeographical

country:US


Property
Period End2020-12-312019-12-31
Value7362
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization52.348.9

us-gaap:NonUs


Property
Period End2020-12-312019-12-31
Value6664
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization47.751.1

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization us-gaap:PropertyPlantAndEquipmentByType

us-gaap:PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization

opk:AutomobilesandAircraft


Property
Period End2020-12-312019-12-31
Value1010
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization100.0100.0

opk:MachineryMedicalandOtherEquipment


Property
Period End2020-12-312019-12-31
Value193165
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization1833.11650.2

us-gaap:Building


Property
Period End2020-12-312019-12-31
Value2118
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization207.3184.1

us-gaap:ConstructionInProgress


Property
Period End2020-12-312019-12-31
Value8.1697.044
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization77.570.2

us-gaap:FurnitureAndFixtures


Property
Period End2020-12-312019-12-31
Value1312
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization128.6125.9

us-gaap:Land


Property
Period End2020-12-312019-12-31
Value2.6022.422
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization24.724.1

us-gaap:LeaseholdImprovements


Property
Period End2020-12-312019-12-31
Value4033
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization386.7335.1

us-gaap:SoftwareAndSoftwareDevelopmentCosts


Property
Period End2020-12-312019-12-31
Value1413
Percentage of PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization139.8138.2

us-gaap:PurchaseObligation

us-gaap:PurchaseObligation


Purchase
Period End2021-06-302021-03-312020-12-312020-09-30
Value135301342196
Percentage of PurchaseObligation100.0100.0100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice


Share
Period End2020-12-31
Value9.15
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue


Share
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value260.00.2321.8863263104853438
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue100.00.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue


Share
Period End2020-12-31
Value26
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice


Share
Period End2020-12-31
Value6.45
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice100.0

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1


Sharebased
Period End2020-12-31
Value4407000.0
Percentage of SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1100.0

us-gaap:SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit

us-gaap:SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit


Significant
Period End2020-12-31
Value1500000.0
Percentage of SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit100.0

us-gaap:Supplies

us-gaap:Supplies


Supplies
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302012-12-312011-12-31
Value14137.2599.43512128.1478.91510129.69312109.0588.207128.5657.636.952119.534108.7739.2981.4411.3191.1231.6261.911.9190.9450.8390.4430.256
Percentage of Supplies100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:TaxCreditCarryforwardAmount us-gaap:TaxCreditCarryforward

us-gaap:TaxCreditCarryforwardAmount

us-gaap:Research


Tax
Period End2020-12-31
Value23
Percentage of TaxCreditCarryforwardAmount100.0

us-gaap:UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued

us-gaap:UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued


Unrecognized
Period End2020-12-312012-12-312011-12-312010-12-31
Value2900000.0000
Percentage of UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued100.00.00.00.0

us-gaap:UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate

us-gaap:UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate


Unrecognized
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value10.013-14.2-12.46.10.70.90.2
Percentage of UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ValuationAllowancesAndReservesBalance us-gaap:ValuationAllowancesAndReservesType

us-gaap:ValuationAllowancesAndReservesBalance

us-gaap:AllowanceForCreditLoss


Valuation
Period End2020-12-312019-12-312018-12-312017-12-312016-12-31
Value2.0551.9341.7581.4461.671
Percentage of ValuationAllowancesAndReservesBalance100.0100.0100.0100.0100.0

us-gaap:InventoryValuationReserve


Valuation
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-312010-12-31
Value2.3212.5372.9566.5650.9451.0510.6390.7771.3130.3250.264
Percentage of ValuationAllowancesAndReservesBalance112.9131.2168.1454.056.60.00.00.00.00.00.0

us-gaap:ValuationAllowanceOfDeferredTaxAssets


Valuation
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-312010-12-31
Value303193154142554213185595347
Percentage of ValuationAllowancesAndReservesBalance14760.49992.68812.19824.53316.30.00.00.00.00.00.0

Line plots across dimensions of each concept


COGS Ratio
us-gaap:ProductOrService
(None,)
C O G S  Ratious-gaap: Product Or Service
TTM Greenblatt ROC
_
(None,)
T T M  Greenblatt  R O C_
us-gaap:CostOfGoodsAndServicesSold
us-gaap:ProductOrService
(None,)
Cost Of Goods And Services Soldus-gaap: Product Or Service
us-gaap:OperatingIncomeLoss
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments
('us-gaap:OperatingSegments', None)
Operating Income Lossus-gaap: Consolidation Items, us-gaap: Statement Business Segments
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ProductOrService
(None,)
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Product Or Service
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ConsolidationItems, us-gaap:ProductOrService, us-gaap:StatementBusinessSegments
('us-gaap:OperatingSegments', None, 'opk:Pharmaceutical')
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Consolidation Items, us-gaap: Product Or Service, us-gaap: Statement Business Segments
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement
(None, 'opk:TransferOfIntellectualPropertyAndOther', 'us-gaap:Product')
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Counterparty Name, us-gaap: Product Or Service, us-gaap: Type Of Arrangement
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:StatementGeographical
(None,)
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Statement Geographical
us-gaap:Assets
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments
('us-gaap:OperatingSegments', None)
Assetsus-gaap: Consolidation Items, us-gaap: Statement Business Segments
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components
us-gaap:Goodwill
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments
('us-gaap:OperatingSegments', None)
Goodwillus-gaap: Consolidation Items, us-gaap: Statement Business Segments
us-gaap:Goodwill
us-gaap:BusinessAcquisition, us-gaap:StatementBusinessSegments
(None, 'opk:Diagnostics')
Goodwillus-gaap: Business Acquisition, us-gaap: Statement Business Segments
us-gaap:Goodwill
us-gaap:BusinessAcquisition, us-gaap:StatementBusinessSegments
(None, 'opk:Pharmaceutical')
Goodwillus-gaap: Business Acquisition, us-gaap: Statement Business Segments
us-gaap:LongTermDebtCurrent
us-gaap:LongtermDebtType
(None,)
Long Term Debt Currentus-gaap: Longterm Debt Type
us-gaap:LongTermDebt
us-gaap:DebtInstrument, us-gaap:LongtermDebtType
(None, 'us-gaap:ConvertibleDebt')
Long Term Debtus-gaap: Debt Instrument, us-gaap: Longterm Debt Type
us-gaap:LongTermDebt
us-gaap:LongtermDebtType
(None,)
Long Term Debtus-gaap: Longterm Debt Type
us-gaap:LongTermDebt
us-gaap:BalanceSheetLocation
(None,)
Long Term Debtus-gaap: Balance Sheet Location
us-gaap:LongTermDebtNoncurrent
us-gaap:LongtermDebtType
(None,)
Long Term Debt Noncurrentus-gaap: Longterm Debt Type
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components
us-gaap:StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
us-gaap:StatementEquityComponents
(None,)
Stockholders Equity Including Portion Attributable To Noncontrolling Interestus-gaap: Statement Equity Components
us-gaap:DepreciationDepletionAndAmortization
us-gaap:ConsolidationItems, us-gaap:StatementBusinessSegments
('us-gaap:OperatingSegments', None)
Depreciation Depletion And Amortizationus-gaap: Consolidation Items, us-gaap: Statement Business Segments