RARE


Line plots across dimensions of each concept
Line plots across concepts
Tables

Table of contents



us-gaap:CommonStockValue
us-gaap:CounterpartyName

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities
us-gaap:SubsidiarySaleOfStock

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:AllocatedShareBasedCompensationExpense
us-gaap:IncomeStatementLocation

us-gaap:ComprehensiveIncomeNetOfTax

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

us-gaap:IncomeTaxExpenseBenefit

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:OperatingExpenses

us-gaap:OperatingIncomeLoss

us-gaap:OtherComprehensiveIncomeLossNetOfTax
us-gaap:StatementEquityComponents

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:ProfitLoss

us-gaap:ResearchAndDevelopmentExpense
dei:LegalEntity, us-gaap:TypeOfArrangement

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:CounterpartyName, us-gaap:ProductOrService
us-gaap:ProductOrService
us-gaap:ProductOrService, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
us-gaap:ProductOrService, us-gaap:StatementGeographical, us-gaap:TypeOfArrangement
us-gaap:ProductOrService, us-gaap:TypeOfArrangement
us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
us-gaap:StatementGeographical
us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement
us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax

us-gaap:SellingGeneralAndAdministrativeExpense

us-gaap:Assets

us-gaap:Liabilities

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents

us-gaap:AssetsCurrent

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:ShortTermInvestments

us-gaap:AccountsReceivableNetCurrent

us-gaap:InventoryNet

us-gaap:InventoryFinishedGoods

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:PropertyPlantAndEquipmentGross
us-gaap:PropertyPlantAndEquipmentByType

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:IntangibleAssetsNetExcludingGoodwill

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:OtherAssetsNoncurrent

us-gaap:AccountsPayableCurrent

us-gaap:AccruedLiabilitiesCurrent

us-gaap:ContractWithCustomerLiabilityCurrent

us-gaap:LiabilitiesCurrent

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OtherAccruedLiabilitiesCurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive

us-gaap:OperatingLeaseLiability

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents

us-gaap:CommonStockValue
us-gaap:CounterpartyName

us-gaap:AdditionalPaidInCapital

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
us-gaap:StatementEquityComponents

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:DepreciationDepletionAndAmortization

us-gaap:IncreaseDecreaseInAccountsReceivable

us-gaap:IncreaseDecreaseInInventories

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:ProfitLoss

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:DeferredTaxAssetsNet

us-gaap:UnrecognizedTaxBenefits

us-gaap:DeferredTaxAssetsValuationAllowance
us-gaap:CounterpartyName, us-gaap:StatementEquityComponents
rare:AcquisitionOfInvestmentInCommonStock

rare:AllocatedShareBasedCompensationExpenseNetOfCapitalizedInventoryCost
dei:LegalEntity, us-gaap:TypeOfArrangement
rare:AnnualFeesPayable
us-gaap:TypeOfArrangement
rare:ChangeInFairValueOfAdditionalCommonStock
us-gaap:TypeOfArrangement
rare:CollaborativeArrangementsEffectiveReductionOfExpense
us-gaap:TypeOfArrangement
rare:CollaborativeArrangementsEffectiveReductionOfExpenseInResearchAndDevelopmentExpenses
us-gaap:TypeOfArrangement
rare:CollaborativeArrangementsEffectiveReductionOfExpenseInSellingGeneralAndAdministrativeExpenses

rare:ContractWithCustomerLiabilityAdditionsDuringPeriod

rare:ContractWithCustomerLiabilityDeductionsDuringPeriod

rare:CostOfSales
us-gaap:LeaseArrangementType, us-gaap:StatementScenario
rare:DiscountOnLetterOfCreditOnSuccessfulPaymentOfLeaseAmount
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
rare:EstimatedReimbursementOfDeliveringLicenseAndTechnologyServices

rare:IncreaseDecreaseInAccountsPayableAccruedLiabilitiesAndOtherOperatingLiabilities

rare:IncreaseDecreaseInContractLiabilities

rare:IncreaseDecreaseInLeaseLiabilities

rare:IncreaseDecreaseInRightOFUseAssets

rare:IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax
us-gaap:StatementEquityComponents

rare:IssuanceOfCommonStockUponExerciseOfWarrantsAndUnderEquityPlanAwardsNetOfTax
us-gaap:StatementEquityComponents

rare:IssuanceOfCommonStockValueInConnectionWithLicenseAgreement
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
us-gaap:StatementEquityComponents
dei:LegalEntity, us-gaap:TypeOfArrangement
rare:MilestonePaymentsReceived

rare:NonCashCollaborationRoyaltyRevenue

rare:NonCashInterestExpenseOnLiabilityRelatedToSaleOfFutureRoyalties
us-gaap:SubsidiarySaleOfStock
rare:OptionToSellCommonStockAggregateOfferingPrice
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
rare:PaymentForPurchaseOfCommonStock
us-gaap:SubsequentEventType, us-gaap:TypeOfArrangement
us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType
rare:PaymentsMadeUnderAgreement
us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:SubsequentEventType
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
rare:PremiumFromStockPurchaseAgreement

rare:ProceedsFromIssuanceOfCommonStockAtMarketOffering

rare:ProceedsFromIssuanceOfCommonStockInConnectionWithLicenseAgreement
us-gaap:StatementGeographical, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
rare:ProfitLossSharingPercentageOnCommercializingProducts
us-gaap:StatementScenario, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
rare:ProfitLossSharingPercentageOnNetSales

rare:StockIssuedDuringPeriodValueAtMarketOffering
us-gaap:StatementEquityComponents
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
rare:TransactionPriceOfLicenseAgreement
us-gaap:TypeOfArrangement
rare:TransferOfFairValueOnAdditionalExerciseOfOptions
us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType
rare:UpfrontPaymentForInProcessResearchAndDevelopmentExpense

us-gaap:AccretionAmortizationOfDiscountsAndPremiumsInvestments
us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement
us-gaap:ContractWithCustomerLiabilityRevenueRecognized
us-gaap:CounterpartyName
us-gaap:DeferredRevenueRevenueRecognized1

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations

us-gaap:EquitySecuritiesFvNiGainLoss
us-gaap:ShortTermDebtType
us-gaap:FairValueAdjustmentOfWarrants
us-gaap:CounterpartyName, us-gaap:StatementEquityComponents
us-gaap:FairValueOptionChangesInFairValueGainLoss1
us-gaap:StatementEquityComponents, us-gaap:TypeOfArrangement
us-gaap:TypeOfArrangement

us-gaap:ForeignCurrencyTransactionGainLossBeforeTax

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:InvestmentIncomeInterest

us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax

us-gaap:OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax

us-gaap:OtherNoncashIncomeExpense

us-gaap:PaymentsToAcquireAvailableForSaleSecurities

us-gaap:PaymentsToAcquireAvailableForSaleSecuritiesDebt

us-gaap:PaymentsToAcquireEquityMethodInvestments
us-gaap:SubsidiarySaleOfStock
us-gaap:ProceedsFromIssuanceOfCommonStock
us-gaap:TypeOfArrangement

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions

us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities

us-gaap:ProceedsFromPaymentsForOtherFinancingActivities

us-gaap:ProceedsFromSaleOfAvailableForSaleSecurities

us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
us-gaap:RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
us-gaap:CounterpartyName, us-gaap:StatementEquityComponents
us-gaap:UnrealizedGainLossOnInvestments
us-gaap:StatementEquityComponents, us-gaap:TypeOfArrangement

rare:ContractLiabilitiesCurrent

rare:ContractLiabilitiesNoncurrent

rare:DeferredTaxAssetFixedAssetsAndIntangibles

rare:DeferredTaxAssetsLiabilityRelatedToSaleOfFutureRoyalties

rare:DeferredTaxAssetsStockOption

rare:EquityInvestmentsNoncurrent
us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:SubsequentEventType
rare:FutureContingentMilestonePayments

rare:InvestmentInEquitySecurities

rare:LiabilityRelatedToSaleOfFutureRoyalties

rare:OperatingAndFinanceLeaseLiability

rare:OperatingAndFinanceLeaseLiabilityCurrent

rare:OperatingAndFinanceLeaseLiabilityDueAfterYearFive

rare:OperatingAndFinanceLeaseLiabilityNoncurrent

rare:OperatingAndFinanceLeaseLiabilityPaymentsDue

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueNextTwelveMonths

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearFive

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearFour

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearThree

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearTwo

rare:OperatingAndFinanceLeaseLiabilityUndiscountedExcessAmount

rare:PercentageOfGrossAccountsReceivableBalance
us-gaap:CounterpartyName
rare:ReceivableRelatedToLicenseAgreementCurrent
us-gaap:CounterpartyName, us-gaap:BalanceSheetLocation

rare:ResearchClinicalStudyAndManufacturingExpenses
us-gaap:ProductOrService
rare:SalesReserves
us-gaap:ProductOrService, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
us-gaap:AccountsReceivableNet
us-gaap:ProductOrService, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
us-gaap:AccruedLiabilitiesCurrentAndNoncurrent

us-gaap:AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax

us-gaap:AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax

us-gaap:AvailableForSaleSecurities
us-gaap:FairValueByAssetClass
us-gaap:InvestmentType

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
us-gaap:FairValueByAssetClass
us-gaap:InvestmentType

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
us-gaap:FairValueByAssetClass
us-gaap:InvestmentType

us-gaap:AvailableForSaleSecuritiesAmortizedCost
us-gaap:FairValueByAssetClass
us-gaap:InvestmentType

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
us-gaap:CounterpartyName
us-gaap:ContractWithCustomerLiability

us-gaap:ContractualObligationDueInNextTwelveMonths
us-gaap:OtherCommitments

us-gaap:ContractualObligationDueInSecondYear
us-gaap:OtherCommitments
us-gaap:CounterpartyName, us-gaap:ShortTermDebtType
us-gaap:DebtInstrumentFaceAmount
us-gaap:ShortTermDebtType
us-gaap:CounterpartyName, us-gaap:TypeOfArrangement
us-gaap:DebtInstrumentInterestRateEffectivePercentage

us-gaap:DeferredIncomeTaxLiabilities
us-gaap:FairValueByAssetClass
us-gaap:FiniteLivedIntangibleAssetsByMajorClass
us-gaap:PropertyPlantAndEquipmentByType

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards
us-gaap:IncomeTaxAuthority
us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration
us-gaap:IncomeTaxAuthority, us-gaap:TaxCreditCarryforward

us-gaap:DeferredTaxAssetsOther

us-gaap:DeferredTaxAssetsTaxCreditCarryforwards
us-gaap:IncomeTaxAuthority
us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals

us-gaap:EmployeeRelatedLiabilitiesCurrent

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiabilityCurrent

us-gaap:FinanceLeaseLiabilityNoncurrent

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueYearTwo

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent
us-gaap:CounterpartyName, us-gaap:ShortTermDebtType
us-gaap:InterestReceivable
us-gaap:ShortTermDebtType

us-gaap:InventoryWorkInProcess
us-gaap:CounterpartyName, us-gaap:ShortTermDebtType
us-gaap:InvestmentOwnedAtFairValue
us-gaap:ShortTermDebtType

us-gaap:InvestmentsFairValueDisclosure
us-gaap:CounterpartyName, us-gaap:StatementEquityComponents
us-gaap:FairValueByAssetClass
us-gaap:FairValueByAssetClass, us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:InvestmentType
us-gaap:InvestmentType
us-gaap:StatementEquityComponents, us-gaap:TypeOfArrangement
us-gaap:TypeOfArrangement

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent
us-gaap:BalanceSheetLocation, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement
us-gaap:OtherReceivables

us-gaap:RestrictedCashCurrent

us-gaap:RestrictedCashNoncurrent
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice

us-gaap:UndistributedEarningsOfForeignSubsidiaries

Plots across concepts


IncomeStatement
Net Income Loss
Expenses
Other Nonoperating Income Expense
Balance Sheet
Operating Lease Right Of Use Asset
Assets
Inventory Net
Current Assets
Inventory Net
NonCurrent Assets
Other Assets Noncurrent
PropertyPlantAndEquipmentNet
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Liabilities
Operating Lease Liability
Current Liabilities
Contract With Customer Liability Current
Stockholders Equity
Retained Earnings Accumulated Deficit
CashFlow
Net Income Loss
NetCashProvidedByUsedInOperatingActivities
Net Income Loss
NetCashProvidedByUsedInInvestingActivities
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInFinancingActivities
Proceeds From Payments For Other Financing Activities
Shares
Weighted Average Number Of Share Outstanding Basic And Diluted
OperatingLeaseLiability
Operating Lease Liability Current
LesseeOperatingLeaseLiabilityPaymentsDue
Lessee Operating Lease Liability Undiscounted Excess Amount
InventoryNet
Inventory Finished Goods

Tables

  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:CommonStockValue ███▆▆▆▆▆▆▅▄▄▄▄▂▂▁▁▁0.0680.0670.0670.0610.060.0590.0580.0580.0580.0570.0510.0510.050.050.0440.0420.0410.040.039
us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding 67.607752NANANA61.146231NANANA57.51930853.209215NANANA49.077742NANANANANA
us-gaap:WeightedAverageNumberOfSharesOutstandingBasic 67.607752NANANA59.995617NANANA57.51930853.209215NANANA48.190511NANANANANA
us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted NA67.102342NA60.687177NA57.995999NA57.70769457.51930853.209215NA50.31977249.819528NANA42.471606NA39.55192339.028701
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount █▁8.5000688.118221NA8.6627015.2149888.585289NA8.33828.378297.618311NA7.4239747.89435.150737NA6.016985NA5.3458974.639575
us-gaap:EarningsPerShareBasic -1.81NA-0.37-1.130.42-2.05NANA-1.72-1.82-1.73-1.74-1.060.63NANANANANA
us-gaap:EarningsPerShareDiluted -1.81NA-0.37-1.130.41-2.05NANA-1.72-1.82-1.73-1.74-1.060.62NANANANANA
us-gaap:EarningsPerShareBasicAndDiluted NA-2.03-0.33999999999999986-1.13NA-2.05-1.62-1.96-1.72-1.82-1.75-1.74-1.06NA-1.89-1.87-1.75-1.64-1.46
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:AllocatedShareBasedCompensationExpense █▇▆▅▆▅▅▅▆▅▅▅▅▄▅▄▂▂▁27.14224.29822.81320.34122.40920.17219.6619.90722.20720.22121.0820.66719.56318.79719.54117.1813.53813.69410.86
us-gaap:ComprehensiveIncomeNetOfTax ▂▁▆▄█▂▃▂▃▃▃▃▄█▃▃▄▄▄-122.252-136.774-24.335-69.11628.144-120.423-93.881-113.32-98.769-96.271-88.049-87.066-52.43634.987-80.007-82.408-70.394-65.147-56.763
us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest ▂▁▆▄█▂▃▂▃▃▃▃▅█▃▃▄▄▄-121.965-135.762-23.941-68.53225.73-118.616-91.244-112.701-98.959-96.54-87.7-87.063-52.62630.292-97.948-79.223-71.252-64.907-56.923
us-gaap:IncomeTaxExpenseBenefit ▇▇▇▇▇▇█▇▇▇▇▇▇▇▁▇0.4630.3790.070.3130.4150.4092.5610.2930.2130.2160.1260.2470.1020.039-16.2170.004NANANA
us-gaap:NetIncomeLoss ▂▁▆▄█▂▃▂▃▃▃▃▅█▃▃▄▄▄-122.428-136.141-24.011-68.84525.315-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830.253-81.731-79.227-71.287-64.907-56.923
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▂▁▆▄█▂▃▂▃▃▃▃▅█-122.428-136.141-24.011-68.84525.315-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830.253NANANANANA
us-gaap:OperatingExpenses ▆█▇▄▄▆▄▅▅▄▃▃▃▃▃▂▂▁▁169.751205.964187.623131.785124.764156.974130.045143.833136.623117.386106.601101.409107.694107.16499.24883.91170.55465.89458.07
us-gaap:OperatingIncomeLoss ▅▂▃█▇▁▄▁▂▃▄▄▄▃▃▅▆▆▇-82.776-106.569-96.081-50.315-63.055-120.665-94.452-118.033-112.474-99.214-90.34-89.646-94.9-96.487-96.834-83.713-70.549-65.783-58.053
us-gaap:OtherComprehensiveIncomeLossNetOfTax ▄▃▄▄▆▃▄▄▄▄▄▄▄█▅▁▅▄▄0.176-0.633-0.324-0.2712.829-1.398-0.076-0.3260.4030.485-0.2230.2440.2924.7341.724-3.1810.893-0.240.16
us-gaap:OtherNonoperatingIncomeExpense ▅▄▅▆▅▅▅▅▅▅▅▅▅▁▄█▄▅▅-0.067-0.7950.2990.5470.217-0.4560.154-0.153-0.376-0.4120.013-0.147-0.496-4.958-1.8383.373-1.615-0.0460.159
us-gaap:ProfitLoss ▂▁▆▄█▂▃▂▃▃▃▃▅█-122.428-136.141-24.011-68.84525.315-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830.253NANANANANA
us-gaap:ResearchAndDevelopmentExpense ▆█▇▄▄▆▄▅▅▃▃▃▃▃▂▂▁▁▁113.205147.518131.187.31480.709112.96183.061100.14496.04578.10571.61870.04176.83575.50461.52760.41250.74648.71143.332
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax ▇█▇▇▅▄▄▃▃▂▂▂▂▂▁▁▁▁▁86.97599.39591.54281.4761.70936.30935.59325.824.14918.17216.26111.76312.79410.6772.4140.1980.0050.1110.017
 us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax us-gaap:CounterpartyName,us-gaap:ProductOrService,us-gaap:TypeOfArrangement rare:DaiichiSankyoCoLtd,rare:SublicenseAgreement,rare:LicenseAndTechnologyAccessAgreement▁█▁0.08.00.0NANANANANANANANANANANANANANANANA
us-gaap:SellingGeneralAndAdministrativeExpense ██▇▅▅▇▅▅▅▅▄▃▃▃▄▁53.4153.25851.04242.12342.25247.51641.87741.00639.81238.82934.47631.09530.71831.43537.7223.499NANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:Assets ▇▇█▅▆▅▅▃▄▄▃▃▃▃▁▁▂▁▁1512.4441597.7631759.5551268.3851314.0411233.141135.496879.944958.9271007.759719.558765.145806.022817.35490.753435.047540.626515.166481.951
us-gaap:Liabilities ▇▇████▆▂▂▂▂▂▂▂▂▁▁▁▁540.273543.181605.18602.194618.454623.994481.732152.679139.14121.03110.65102.549102.05193.693107.29969.48966.65259.27638.056
us-gaap:LiabilitiesAndStockholdersEquity ▇▇█▅▆▅▅▃▄▄▃▃▃▃▁▁▂▁▁1512.4441597.7631759.5551268.3851314.0411233.141135.496879.944958.9271007.759719.558765.145806.022817.35490.753435.047540.626515.166481.951
us-gaap:StockholdersEquity ▆▇█▄▄▃▄▄▅▆▃▄▄▄▁▁▂▂▂972.1711054.5821154.375666.191695.587609.146653.764727.265819.787886.729608.908662.596703.971723.657383.454365.558473.974455.89443.895
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:AssetsCurrent ▆▆█▅▅▅▅▃▄▅▃▃▃▃▁▂▂▂▂949.4921070.9361295.304872.003906.039894.318851.017613.486699.431786.887522.369567.48604.743581.58269.583390.903401.695416.785411.084
us-gaap:CashAndCashEquivalentsAtCarryingValue ▄▄█▃▄▄▅▂▂▃▂▁▂▃▁▁▂▂▁290.875383.794713.526197.486335.639298.19433.584122.577131.337269.712113.43282.956110.854226.73100.48860.407161.12142.2855.069
us-gaap:ShortTermInvestments NANANA568.034477.777365.088321.646404.481486.949445.604346.274420.142436.278314.616134.005310.659219.028254.15336.734
us-gaap:AccountsReceivableNetCurrent ▆▆▆▇▄▇█▆▅▄▃▂▄▁▁24.7225.03223.09327.76214.89329.32732.84423.12120.90115.62812.749.15517.4253.6715.172NANANANA
us-gaap:InventoryNet █▇▇█▆▆▆█▇▆▄▃▂▂▁15.08312.46213.04814.45711.06111.37511.54614.13813.63210.9487.0655.5563.3422.0680.757NANANANA
us-gaap:InventoryFinishedGoods ███▆▅▅▅▅▄▄▃▂▂▁▁5.6265.6795.8644.2463.3843.1443.3553.3852.5682.1871.6810.9560.4620.260.02NANANANA
us-gaap:PrepaidExpenseAndOtherAssetsCurrent ▇█▇▇▇█▆▅▅▅▄▅▄▃▃▁▁▁▁63.93368.03457.6364.26458.19664.78851.39749.16946.61244.99542.85849.67136.84433.95328.719.37620.13618.94417.799
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:PropertyPlantAndEquipmentGross NANA110.907NANANA70.336NANANA38.252NANANA32.828NA23.216NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType rare:ComputerEquipmentAndSoftwareNANA8.181NANANA7.817NANANA7.342NANANA6.745NANANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType rare:ResearchAndDevelopmentEquipmentNANA28.394NANANA17.881NANANA9.856NANANA7.696NA2.154NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:ConstructionInProgressNANA17.649NANANA24.271NANANA1.97NANANA0.429NA0.037NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:LandNANA11.722NANANANANANANANANANANANANANANANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:LeaseholdImprovementsNANA39.356NANANA16.871NANANA15.705NANANA15.085NA12.486NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:OfficeEquipmentNANA5.051NANANA3.496NANANA3.379NANANA2.873NA2.595NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:OtherCapitalizedPropertyPlantAndEquipmentNANA0.554NANANANANANANANANANANANANANANANA
us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment NANA37.392NANANA25.988NANANA18.206NANANA10.991NA6.161NANA
us-gaap:PropertyPlantAndEquipmentNet █▇▆▄▄▃▃▂▂▁▁▁▁▁▁▁▁▁▁104.56887.5773.51548.77348.33947.59644.34831.87725.31721.69620.04619.82820.85820.8321.83716.0317.05518.22617.054
us-gaap:IntangibleAssetsNetExcludingGoodwill ▂▂▂▂▂▁▁▁▁▁▁▂▃▆█130.95131.031131.113131.194131.275129.0129.0129.02129.069129.086129.223130.232132.776137.122141.545NANANANA
us-gaap:OperatingLeaseRightOfUseAsset ▇▇█▇▇▆▄▄▅▁38.61938.51140.52437.59737.06735.82730.32831.71133.35623.024NANANANANANANANANA
us-gaap:OtherAssetsNoncurrent █▆▆▃▂▃▂▂▂▂▂▂▂▁▁▁▁▁▁12.6688.9298.8125.0922.6274.8623.4713.1113.1812.663.5143.1993.2391.5741.3151.3451.8371.8681.446
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:AccountsPayableCurrent █▅▄▃▃▅▄▄▂▄▄▂▃▂▃▃▁▂▂21.7915.74412.92310.859.01414.40512.87113.468.74312.66412.2758.19810.3147.5698.8869.2885.3646.6166.954
us-gaap:AccruedLiabilitiesCurrent ▇▆█▆▅▅▆▅▄▃▄▄▄▃▄▃▃▃▁91.0682.699108.49179.65371.88767.71983.19469.55759.26448.95762.4558.48355.73549.29161.42754.27854.55443.48724.714
us-gaap:ContractWithCustomerLiabilityCurrent ▁▂▄▆█3.91225.08966.568102.898134.898NANA0.0160.055NANANA1.244NA5.986NANANANA
us-gaap:LiabilitiesCurrent ▅▅▇▇█▇▄▃▃▂▃▂▂▂▂▂▂▂▁127.067127.044189.609201.186219.729196.858103.390.30775.00666.8874.72566.68166.04957.58371.01464.26160.25950.43131.983
us-gaap:OperatingLeaseLiabilityCurrent NANA8.5167.7857.2587.4877.2357.296.9995.259NANANANANANANANANA
us-gaap:OtherAccruedLiabilitiesCurrent ██▇▅▄▄▆▅▃▃▃▂▂▂▂▂▁▁▁26.96425.39324.4416.15914.33213.6518.97616.90411.3349.5569.0958.458.2517.3778.0926.6465.0854.034.612
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:OperatingLeaseLiabilityNoncurrent NANA38.5536.66836.30834.95829.75731.20632.96822.984NANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo NANA11.904NANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree NANA12.148NANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour NANA10.319NANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive NANA6.247NANANANANANANANANANANANANANANANA
us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive NANA3.456NANANANANANANANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:StockholdersEquity ▆▇█▄▄▃▄▄▅▆▃▄▄▄▁▁▂▂▂972.1711054.5821154.375666.191695.587609.146653.764727.265819.787886.729608.908662.596703.971723.657383.454365.558473.974455.89443.895
us-gaap:CommonStockValue ███▆▆▆▆▆▆▅▄▄▄▄▂▂▁▁▁0.0680.0670.0670.0610.060.0590.0580.0580.0580.0570.0510.0510.050.050.0440.0420.0410.040.039
us-gaap:AdditionalPaidInCapital ███▆▆▆▅▅▅▅▄▄▄▃▂▂▂▁▁2850.0162810.1762773.1952260.6822220.9632162.6672086.8632066.4832045.6852013.8591639.7731605.4121559.7221526.9721221.7621123.8611003.561915.084837.943
us-gaap:RetainedEarningsAccumulatedDeficit ▁▂▂▂▃▃▃▄▄▅▅▅▆▆▆▆▇██-1878.145-1755.717-1619.576-1595.565-1526.72-1552.035-1433.01-1339.205-1226.211-1127.039-1030.283-942.457-855.147-802.419-832.672-750.941-530.533-459.246-394.339
us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax ▇▇███▆▇▇▇▇▆▇▆▆▂▁█▇▇0.2320.0560.6891.0131.284-1.545-0.147-0.0710.255-0.148-0.633-0.41-0.654-0.946-5.68-7.4040.9050.0120.252
us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue █▆▄▂▄▂▁▂▄▂▄▃▂▁27.09924.2222.72120.52722.42820.15719.17119.89422.4920.47522.13820.66719.56318.797NANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:NetCashProvidedByUsedInOperatingActivities ▄▁▄▄█▃▃▃▃▃▄▄▃▃▃▄-65.356-159.346-62.452-61.96787.351-95.152-72.039-88.506-89.063-95.775-55.853-69.157-76.078-89.478-81.823-61.993NANANA
us-gaap:NetCashProvidedByUsedInInvestingActivities ▅▁█▃▃▃▇█▄▃▇▆▄▄▇▆-41.246-182.42497.901-95.758-86.139-95.12567.26679.314-58.426-101.19373.56116.205-52.069-71.02857.39129.788NANANA
us-gaap:NetCashProvidedByUsedInFinancingActivities ▁▁█▁▁▂▆▁▁▆▁▁▁▅▂▁12.62812.649489.71119.13535.81155.615315.4430.9049.342353.61712.24225.02413.168286.41964.4391.333NANANA
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect ▃▁█▃▄▃▆▄▃▅▄▃▃▅▄▃-93.526-329.892526.04-138.15337.448-135.285311.007-8.76-137.979156.45130.095-27.898-115.875126.16240.368-30.344NANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:DepreciationDepletionAndAmortization ▄▄▄▄▄▄▃▃▃▃▄▆██▃▂▂▁▁3.1213.3673.1333.0923.1842.8522.1692.1452.1062.1192.9434.3556.086.162.5141.0951.1571.0310.692
us-gaap:IncreaseDecreaseInAccountsReceivable ▅▅▃█▁▄▇▅▆▅▅▃█▄-0.3241.993-4.71412.829-14.455-3.59.7022.2415.2622.8993.6-8.2713.754-1.501NANANANANA
us-gaap:IncreaseDecreaseInInventories ▇▃▂▇▃▃▁▄▆█▄▆▅▅2.648-0.474-1.2893.156-0.372-0.149-2.1530.5642.3933.6470.4842.2141.2741.311NANANANANA
us-gaap:NetCashProvidedByUsedInOperatingActivities ▄▁▄▄█▃▃▃▃▃▄▄▃▃▃▄-65.356-159.346-62.452-61.96787.351-95.152-72.039-88.506-89.063-95.775-55.853-69.157-76.078-89.478-81.823-61.993NANANA
us-gaap:NetIncomeLoss ▂▁▆▄█▂▃▂▃▃▃▃▅█▃▃▄▄▄-122.428-136.141-24.011-68.84525.315-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830.253-81.731-79.227-71.287-64.907-56.923
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▂▁▆▄█▂▃▂▃▃▃▃▅█-122.428-136.141-24.011-68.84525.315-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830.253NANANANANA
us-gaap:ProfitLoss ▂▁▆▄█▂▃▂▃▃▃▃▅█-122.428-136.141-24.011-68.84525.315-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830.253NANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:NetCashProvidedByUsedInInvestingActivities ▅▁█▃▃▃▇█▄▃▇▆▄▄▇▆-41.246-182.42497.901-95.758-86.139-95.12567.26679.314-58.426-101.19373.56116.205-52.069-71.02857.39129.788NANANA
us-gaap:PaymentsToAcquirePropertyPlantAndEquipment ▇▆█▂▂▅▅▂▃▂▁▁▁▁▁▁▁▂▂20.07116.41421.9463.784.08314.09611.55.0335.243.0591.1921.0321.3770.4750.8991.0330.6663.0015.044
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
us-gaap:NetCashProvidedByUsedInFinancingActivities ▁▁█▁▁▂▆▁▁▆▁▁▁▅▂▁12.62812.649489.71119.13535.81155.615315.4430.9049.342353.61712.24225.02413.168286.41964.4391.333NANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value0.0680.0670.0670.0610.060.0590.0580.0580.0580.0570.0510.0510.050.050.0440.0420.0420.0420.0410.040.0390.0390.0390.0390.0360.0360.0320.0320.030.030.004
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStockValue us-gaap:CounterpartyName

rare:SolidBiosciencesInc


Common
Period End2020-10-31
Value26
Percentage of CommonStockValue0.0
Percentage of Assets0.0
Percentage of Assets rare:SolidBiosciencesInc0.0

Weighted Average Number Of Diluted Shares Outstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding


Weighted
Period End2021-06-302020-06-302019-06-302019-03-312018-03-312017-03-31
Value676157534941
Percentage of WeightedAverageNumberOfDilutedSharesOutstanding100.0100.0100.0100.0100.0100.0

Weighted Average Number Of Shares Outstanding Basic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic


Weighted
Period End2021-06-302020-06-302019-06-302019-03-312018-03-312017-03-312015-06-302015-03-312014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value67595753484135343130213.6216543.5032143.461161
Percentage of WeightedAverageNumberOfSharesOutstandingBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Weighted Average Number Of Share Outstanding Basic And Diluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted


Weighted
Period End2021-03-312020-09-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302017-09-302017-06-302017-03-312016-09-302016-06-302016-03-312015-09-302015-06-302015-03-312014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value67605757575350494242413939383835343130213.6216543.2578062.893997
Percentage of WeightedAverageNumberOfShareOutstandingBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount


Antidilutive
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-312016-09-302016-06-302016-03-312015-09-302015-06-302015-03-312014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value8.5000688.1182218.6627015.2149888.5852898.33828.378297.6183117.4239747.89435.1507376.0169855.924125.4780085.3458974.6395754.1907733.838483.2265593.0570533.1151142.9148162.668804212121
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecurities

rare:OptionsToPurchaseCommonStockAndRSUs


Antidilutive
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-31
Value8.4914478.0845858.6274195.2040368.4044118.1554068.2207337.4265567.2429897.7352315.1507375.8352715.767665.303718
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount99.999.699.699.897.997.898.197.597.698.0100.097.097.496.8

us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount us-gaap:SubsidiarySaleOfStock

us-gaap:EmployeeStock


Antidilutive
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302017-09-302017-06-302017-03-31
Value0.0086210.0336360.0352820.0109520.0624340.0330940.0078570.0420550.0312850.0093690.0320140.006760.02459
Percentage of AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount0.10.40.40.20.70.40.10.60.40.10.50.10.4

Earnings Per Share Basic

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareBasic


Earnings
Period End2021-06-302020-12-312020-09-302020-06-302020-03-312019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-03-31
Value-1.81-0.37-1.130.42-2.05-1.72-1.82-1.73-1.74-1.060.63-1.63
Percentage of EarningsPerShareBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Diluted

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareDiluted


Earnings
Period End2021-06-302020-12-312020-09-302020-06-302020-03-312019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-03-31
Value-1.81-0.37-1.130.41-2.05-1.72-1.82-1.73-1.74-1.060.62-1.63
Percentage of EarningsPerShareDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Basic And Diluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:EarningsPerShareBasicAndDiluted


Earnings
Period End2021-03-312020-12-312020-09-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-2.03-0.34-1.13-2.05-1.62-1.96-1.72-1.82-1.75-1.74-1.06-1.89-1.87-1.72-1.63-1.75-1.64-1.46-1.35-1.42-1.03-0.83-0.63-0.52-0.5-0.45-0.85-4.98-3.48-3.32-2.84
Percentage of EarningsPerShareBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Allocated Share Based Compensation Expense

us-gaap:AllocatedShareBasedCompensationExpense

us-gaap:AllocatedShareBasedCompensationExpense


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value272422202220191922202120191819171614131310109.4897.8965.0912.4082.0011.6520.9460.7950.210.0710.1850.191
Percentage of AllocatedShareBasedCompensationExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax31.224.424.925.036.355.655.277.292.0111.3129.6175.7152.9176.1809.58676.80.00.0270760.012336.963882.40.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AllocatedShareBasedCompensationExpense us-gaap:IncomeStatementLocation

us-gaap:CostOfSales


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value0.2230.3790.5140.1330.1120.0680.680.3190.0510.034
Percentage of AllocatedShareBasedCompensationExpense0.81.62.30.70.50.33.51.60.20.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.30.40.60.20.20.21.91.20.20.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:CostOfSales0.00.00.00.00.00.00.00.00.00.0

us-gaap:ResearchAndDevelopmentExpense


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value15131211121010101211101111119.6849.951108.5438.0488.2946.4956.5756.5725.5553.1321.8411.5591.20.6520.7050.1540.0570.0520.03
Percentage of AllocatedShareBasedCompensationExpense55.655.555.456.757.454.252.553.454.255.551.357.459.559.849.657.959.758.959.460.659.864.469.370.461.576.577.972.668.988.773.380.328.115.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax17.413.613.814.220.830.129.041.249.861.866.6100.891.0105.3401.25025.80.00.0160960.07472.138205.90.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ResearchAndDevelopmentExpense0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:SellingGeneralAndAdministrativeExpenses


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value11109.6688.6759.4419.1758.6668.959108.957108.8097.9197.559.8577.2296.765.956
Percentage of AllocatedShareBasedCompensationExpense43.642.942.442.642.145.544.145.045.644.348.042.640.540.250.442.140.341.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax13.610.510.610.615.325.324.334.741.949.362.274.961.970.7408.33651.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:SellingGeneralAndAdministrativeExpenses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Comprehensive Income Net Of Tax

us-gaap:ComprehensiveIncomeNetOfTax

us-gaap:ComprehensiveIncomeNetOfTax


Comprehensive
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-122.252-136.774-24.335-69.11628-120.423-93.881-113.32-98.769-96.271-88.049-87.066-52.43634-80.007-82.408-77.345-68.964-70.394-65.147-56.763-51.797-56.049-39.062-29.902-21.299-16.794-15.919-13.587-13.687-11.292-8.365-8.656-6.735
Percentage of ComprehensiveIncomeNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.6-137.6-26.6-84.845.6-331.7-263.8-439.2-409.0-529.8-541.5-740.2-409.8327.7-3314.3-41620.20.00.0-1407880.0-58691.0-333900.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-30
Value-121.965-135.762-23.941-68.53225-118.616-91.244-112.701-98.959-96.54-87.7-87.063-52.62630-97.948-79.223-72.877-68.29-71.252-64.907-56.923
Percentage of IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.2-136.6-26.2-84.141.7-326.7-256.4-436.8-409.8-531.3-539.3-740.1-411.3283.7-4057.5-40011.60.00.0-1425040.0-58474.8-334841.2

Income Tax Expense Benefit

us-gaap:IncomeTaxExpenseBenefit

us-gaap:IncomeTaxExpenseBenefit


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value463000.0379000.070000.0313000.0415000.0409000.02561000.0293000.0213000.0216000.0126000.0247000.0102000.039000.0-16217000.04000.014000.0
Percentage of IncomeTaxExpenseBenefit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.50.40.10.40.71.17.21.10.91.20.82.10.80.4-671.82.00.0

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-122.428-136.141-24.011-68.84525-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830-81.731-79.227-72.891-68.29-71.287-64.907-56.923-52.757-55.22-39.232-29.787-21.379-16.738-15.849-13.585-13.63-11.317-8.428-8.59-6.735
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.8-137.0-26.2-84.541.0-327.8-263.5-438.0-410.7-532.4-540.1-742.2-412.1283.3-3385.7-40013.60.00.0-1425740.0-58474.8-334841.20.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-122.428-136.141-24.011-68.84525-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.8-137.0-26.2-84.541.0-327.8-263.5-438.0-410.7-532.4-540.1-742.2-412.1283.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Operating Expenses

us-gaap:OperatingExpenses

us-gaap:OperatingExpenses


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value169205187131124156130143136117106101107107998378697065585356393021161513109.5257.7618.2476.747
Percentage of OperatingExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax195.2207.2205.0161.8202.2432.3365.4557.5565.8646.0655.6862.1841.81003.74111.442379.30.00.01411080.059364.0341588.20.00.00.00.00.00.00.00.00.00.00.00.00.0

Operating Income Loss

us-gaap:OperatingIncomeLoss

us-gaap:OperatingIncomeLoss


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-82776000.0-106570000.0-96081000.0-50315000.0-63055000.0-120660000.0-94452000.0-118030000.0-112470000.0-99214000.0-90340000.0-89646000.0-94900000.0-96487000.0-96834000.0-83713000.0-78441000.0-69954000.0-70549000.0-65783000.0-58053000.0-53622000.0-56158000.0-39936000.0-30142000.0-21502000.0-16943000.0-15835000.0-13661000.0-10339000.0-9525000.0-7761000.0-8247000.0-6747000.0
Percentage of OperatingIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-95.2-107.2-105.0-61.8-102.2-332.3-265.4-457.5-465.8-546.0-555.6-762.1-741.8-903.7-4011.4-42279.30.00.0-1410980.0-59264.0-341488.20.00.00.00.00.00.00.00.00.00.00.00.00.0

Other Comprehensive Income Loss Net Of Tax

us-gaap:OtherComprehensiveIncomeLossNetOfTax

us-gaap:OtherComprehensiveIncomeLossNetOfTax


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-30
Value176000.0-633000.0-324000.0-271000.02829000.0-1398000.0-76000.0-326000.0403000.0485000.0-223000.0244000.0292000.04734000.01724000.0-3181000.0-4454000.0-674000.0893000.0-240000.0160000.0960000.0-829000.0170000.0-115000.0
Percentage of OtherComprehensiveIncomeLossNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.2-0.6-0.4-0.34.6-3.9-0.2-1.31.72.7-1.42.12.344.371.4-1606.60.00.017860.0-216.2941.20.00.00.00.0

us-gaap:OtherComprehensiveIncomeLossNetOfTax us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-03-312016-03-31
Value176000.0-633000.0-324000.0-271000.02829000.0-1398000.0-76000.0-326000.0403000.0485000.0-223000.0244000.0292000.04734000.0-674000.0960000.0
Percentage of OtherComprehensiveIncomeLossNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.2-0.6-0.4-0.34.6-3.9-0.2-1.31.72.7-1.42.12.344.30.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:AccumulatedOtherComprehensiveIncome0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Other Nonoperating Income Expense

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:OtherNonoperatingIncomeExpense


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-67000.0-795000.0299000.0547000.0217000.0-456000.0154000.0-153000.0-376000.0-412000.013000.0-147000.0-496000.0-4958000.0-1838000.03373000.04413000.0582000.0-1615000.0-46000.0159000.0-119000.020000.031000.0-101000.0-150000.010000.0-185000.076000.0-3291000.0-1851000.0-735000.0-343000.012000.0
Percentage of OtherNonoperatingIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-0.1-0.80.30.70.4-1.30.4-0.6-1.6-2.30.1-1.2-3.9-46.4-76.11703.50.00.0-32300.0-41.4935.30.00.00.00.00.00.00.00.00.00.00.00.00.0

Profit Loss

us-gaap:ProfitLoss

us-gaap:ProfitLoss


Profit
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-122.428-136.141-24.011-68.84525-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830
Percentage of ProfitLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.8-137.0-26.2-84.541.0-327.8-263.5-438.0-410.7-532.4-540.1-742.2-412.1283.3

Research And Development Expense

us-gaap:ResearchAndDevelopmentExpense

us-gaap:ResearchAndDevelopmentExpense


Research
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value1131471318780112831009678717076756160585150484340442923171312118.3538.2046.7627.1995.664
Percentage of ResearchAndDevelopmentExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax130.2148.4143.2107.2130.8311.1233.4388.2397.7429.8440.4595.4600.6707.22548.830511.10.00.01014920.043883.8254894.10.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:ResearchAndDevelopmentExpense dei:LegalEntity, us-gaap:TypeOfArrangement

rare:GeneTxBiotherapeuticsLLC, rare:ProgramAgreementAndUnitholderOptionAgreement


Research
Period End2020-09-302020-06-302020-03-312019-12-312019-09-30
Value0.00.0250.020
Percentage of ResearchAndDevelopmentExpense0.00.022.10.020.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.00.068.90.077.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:GeneTxBiotherapeuticsLLC rare:ProgramAgreementAndUnitholderOptionAgreement0.00.00.00.00.0

Revenue From Contract With Customer Excluding Assessed Tax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312016-09-302016-06-30
Value86999181613635252418161112102.4140.1980.0050.1110.017
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:CounterpartyName, us-gaap:ProductOrService

rare:DaiichiSankyoCoLtd, rare:CollaborationAndLicense


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-30
Value2142373218
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax25.243.041.040.330.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax25.243.041.040.330.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:DaiichiSankyoCoLtd rare:CollaborationAndLicense100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService

rare:CollaborationAndLicense


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value63797566502728211914129.015109.362
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax73.579.581.982.181.375.079.983.779.778.478.776.682.287.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax73.579.581.982.181.375.079.983.779.778.478.776.682.287.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:CollaborationAndLicense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Product


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value181612118.0666.4797.174.2154.9023.9343.4642.7482.2751.3150.2780.198
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax21.116.614.213.813.117.820.116.320.321.621.323.417.812.311.5100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax21.116.614.213.813.117.820.116.320.321.621.323.417.812.311.5100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Royalty


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value4.6893.8723.5673.3313.4822.615
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.43.93.94.15.67.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.43.93.94.15.67.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Royalty100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

us-gaap:Product, us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value2.95.93.03.32.51.61.61.11.00.60.30.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.35.93.34.14.14.44.54.34.13.31.82.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.35.93.34.14.14.44.54.34.13.31.82.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product us-gaap:LicenseAgreementTerms rare:KyowaKirinCollaboration100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService, us-gaap:StatementGeographical, us-gaap:TypeOfArrangement

rare:CollaborationAndLicense, rare:EuropeanUnionAndSwitzerlandAndTurkey, rare:Crysvita


Revenue
Period End2021-06-302020-12-312020-09-302020-06-302019-12-312019-09-30
Value0.2280.00.01.4982.2241.95
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.30.00.02.46.27.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.30.00.02.46.27.6
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:CollaborationAndLicense rare:EuropeanUnionAndSwitzerlandAndTurkey rare:Crysvita100.00.00.0100.0100.0100.0

rare:CollaborationAndRoyalty, rare:EuropeanUnionAndSwitzerlandAndTurkey, rare:KyowaKirinCollaboration


Revenue
Period End2021-06-302020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302019-03-31
Value0.228-0.0020.0021.52.2241.951.9312.015
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.3-0.00.02.46.27.68.011.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.3-0.00.02.46.27.68.011.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:CollaborationAndRoyalty rare:EuropeanUnionAndSwitzerlandAndTurkey rare:KyowaKirinCollaboration100.0100.0100.0100.0100.0100.0100.0100.0

rare:CollaborationAndRoyalty, rare:UnitedStatesAndCanada, rare:KyowaKirinCollaboration


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value41363734292726191711
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax48.036.541.041.848.375.073.575.771.465.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax48.036.541.041.848.375.073.575.771.465.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:CollaborationAndRoyalty rare:UnitedStatesAndCanada rare:KyowaKirinCollaboration100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Royalty, rare:EuropeanUnionAndSwitzerlandAndTurkey, rare:KyowaKirinCollaboration


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value4.6893.8723.5673.3313.4822.615
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.43.93.94.15.67.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.43.93.94.15.67.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Royalty rare:EuropeanUnionAndSwitzerlandAndTurkey rare:KyowaKirinCollaboration100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ProductOrService, us-gaap:TypeOfArrangement

rare:CollaborationAndLicense, rare:Crysvita


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value41363734292726191711
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax48.036.541.041.848.375.073.575.771.465.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax48.036.541.041.848.375.073.575.771.465.7
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:CollaborationAndLicense rare:Crysvita100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:CollaborationAndRoyalty, rare:KyowaKirinCollaboration


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value46404137342928211913
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax53.740.444.945.956.482.279.783.379.476.8
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax53.740.444.945.956.482.279.783.379.476.8
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:CollaborationAndRoyalty rare:KyowaKirinCollaboration100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Product, rare:Crysvita


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value2.95.8722.9143.2772.5491.611.5521.141.0060.5880.350.2680.026
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.35.93.24.04.14.44.44.44.23.22.22.30.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3.35.93.24.04.14.44.44.44.23.22.22.30.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product rare:Crysvita100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Product, rare:Dojolvi


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-30
Value107.0346.393.8621.3321.4441.2580.714
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax11.67.17.04.72.24.03.52.8
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax11.67.17.04.72.24.03.52.8
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product rare:Dojolvi100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Product, rare:Mepsevii


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value5.3993.6073.6564.0764.1853.4254.362.3613.242.6732.652.1272.0071.1190.2780.198
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.23.64.05.06.89.412.29.213.414.716.318.115.710.511.5100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.23.64.05.06.89.412.29.213.414.716.318.115.710.511.5100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Product rare:Mepsevii100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Royalty, rare:Crysvita


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value4.6893.8723.5673.3313.4822.615
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.43.93.94.15.67.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.43.93.94.15.67.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:Royalty rare:Crysvita100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Revenue
Period End2021-06-302020-06-30
Value0.21.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.22.4
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.22.4
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:LicenseAgreementTerms rare:KyowaKirinCollaboration100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:StatementGeographical

rare:AllOther


Revenue
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value6.0163.2043.8173.231.7951.9061.311.1650.8060.5690.2680.026
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.13.54.75.24.95.45.14.84.43.52.30.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax6.13.54.75.24.95.45.14.84.43.52.30.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:AllOther100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

srt:Europe


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value6.75.6375.6115.0026.5484.1573.5632.792.8212.9112.0841.6160.930.6630.1250.198
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax7.75.76.16.110.611.410.010.811.716.012.813.77.36.25.2100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax7.75.76.16.110.611.410.010.811.716.012.813.77.36.25.2100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax srt:Europe100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

srt:LatinAmerica


Revenue
Period End2021-06-302020-06-30
Value4.7083.23
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.45.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax5.45.2
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax srt:LatinAmerica100.0100.0

srt:NorthAmerica


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-30
Value7587827251303021
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax86.988.390.489.284.283.684.684.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax86.988.390.489.284.283.684.684.1
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax srt:NorthAmerica100.0100.0100.0100.0100.0100.0100.0100.0

Revenue From Contract With Customer Including Assessed Tax

us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement

us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax

rare:DaiichiSankyoCoLtd, rare:SublicenseAgreement, rare:LicenseAndTechnologyAccessAgreement


Revenue
Period End2021-06-302021-03-312020-12-31
Value08000000.00
Percentage of RevenueFromContractWithCustomerIncludingAssessedTax0.0100.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax0.08.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax rare:DaiichiSankyoCoLtd rare:SublicenseAgreement rare:LicenseAndTechnologyAccessAgreement0.00.00.0

Selling General And Administrative Expense

us-gaap:SellingGeneralAndAdministrativeExpense

us-gaap:SellingGeneralAndAdministrativeExpense


Selling
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value535351424247414139383431303137232018
Percentage of SellingGeneralAndAdministrativeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax61.453.655.851.768.5130.9117.7158.9164.9213.7212.0264.3240.1294.41562.611868.20.00.0

Assets

us-gaap:Assets

us-gaap:Assets


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value1512159717591268131412331135879958100771976580681749043549754554051548152455960234335519721016217259
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Liabilities

us-gaap:Liabilities

us-gaap:Liabilities


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value54054360560261862348115213912111010210293107696857665938342825231413119.5036.9939.54
Percentage of Liabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets35.734.034.447.547.150.642.417.414.512.015.413.412.711.521.916.013.710.512.311.57.96.65.14.26.94.16.65.55.84.016.0

Liabilities And Stockholders Equity

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:LiabilitiesAndStockholdersEquity


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value1512159717591268131412331135879958100771976580681749043549754554051548152455960234335519721016217259
Percentage of LiabilitiesAndStockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value97210541154666695609653727819886608662703723383365429488473455443489531576319341184199153165-74.821-27.047-7.961
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets64.366.065.652.552.949.457.682.685.588.084.686.687.388.578.184.086.389.587.788.592.193.494.995.893.195.993.494.594.296.0-125.40.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-03-312016-12-312016-03-312015-12-312014-12-312013-12-31
Value0.2320.0560.6891.0131.284-1.545-0.147-0.0710.255-0.148-0.633-0.41-0.654-0.946-5.680.2310.9050.092-0.868-0.1740.011
Percentage of StockholdersEquity0.00.00.10.20.2-0.3-0.0-0.00.0-0.0-0.1-0.1-0.1-0.1-1.50.00.20.0-0.2-0.1-0.0
Percentage of Assets0.00.00.00.10.1-0.1-0.0-0.00.0-0.0-0.1-0.1-0.1-0.1-1.20.00.20.0-0.2-0.10.0
Percentage of Assets us-gaap:AccumulatedOtherComprehensiveIncome0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312012-12-312011-12-31
Value28502810277322602220216220862066204520131639160515591526122110038163240.0080.191
Percentage of StockholdersEquity293.2266.5240.2339.3319.3355.0319.2284.1249.5227.1269.3242.3221.6211.0318.6211.7153.8175.3-0.0-2.4
Percentage of Assets188.4175.9157.6178.2169.0175.4183.8234.8213.3199.8227.9209.8193.5186.8249.0185.6145.9163.70.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value0.0680.0670.0670.0610.060.0590.0580.0580.0580.0570.0510.0510.050.050.0440.0410.0390.0320.0040.0030.003
Percentage of StockholdersEquity0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0-0.0-0.0-0.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value-1878.145-1755.717-1619.576-1595.565-1526.72-1552.035-1433.01-1339.205-1226.211-1127.039-1030.283-942.457-855.147-802.419-832.672-530.533-284.659-139.041-74.836-27.058-8.155
Percentage of StockholdersEquity-193.2-166.5-140.3-239.5-219.5-254.8-219.2-184.1-149.6-127.1-169.2-142.2-121.5-110.9-217.2-111.9-53.6-75.2100.0100.0102.4
Percentage of Assets-124.2-109.9-92.0-125.8-116.2-125.9-126.2-152.2-127.9-111.8-143.2-123.2-106.1-98.2-169.7-98.1-50.9-70.2-125.50.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Assets Current

us-gaap:AssetsCurrent

us-gaap:AssetsCurrent


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value9491070129587290689485161369978652256760458126939041944440141641143045046033635019320615816955
Percentage of AssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets62.867.073.668.769.072.574.969.772.978.172.674.275.071.254.989.984.481.574.380.985.382.180.576.598.198.597.798.097.398.292.6

Cash And Cash Equivalents At Carrying Value

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashAndCashEquivalentsAtCarryingValue


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-312012-12-312011-12-31
Value29038371319733529843312213126911382110226100609015916114255709316652178245317557.4276.04913648610
Percentage of CashAndCashEquivalentsAtCarryingValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets19.224.040.615.625.524.238.213.913.726.815.810.813.827.720.513.918.229.229.827.611.413.516.727.715.350.012.325.310.732.112.50.00.00.00.00.0

Short Term Investments

us-gaap:ShortTermInvestments

us-gaap:ShortTermInvestments


Short
Period End2020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value56847736532140448644534642043631413431030826521925433634134328127316416314713510945
Percentage of ShortTermInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets44.836.429.628.346.050.844.248.154.954.138.527.371.462.148.740.549.369.965.161.446.879.846.282.470.183.563.777.0

Accounts Receivable Net Current

us-gaap:AccountsReceivableNetCurrent

us-gaap:AccountsReceivableNetCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value24252327142932232015129.155173.6715.172
Percentage of AccountsReceivableNetCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.61.61.32.21.12.42.92.62.21.61.81.22.20.41.1

Inventory Net

us-gaap:InventoryNet

us-gaap:InventoryNet


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value151213141111111413107.0655.5563.3422.0680.757
Percentage of InventoryNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.00.80.71.10.80.91.01.61.41.11.00.70.40.30.2

Inventory Finished Goods

us-gaap:InventoryFinishedGoods

us-gaap:InventoryFinishedGoods


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value5626000.05679000.05864000.04246000.03384000.03144000.03355000.03385000.02568000.02187000.01681000.0956000.0462000.0260000.020000.0
Percentage of InventoryFinishedGoods100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.40.40.30.30.30.30.30.40.30.20.20.10.10.00.0

Prepaid Expense And Other Assets Current

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent


Prepaid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value6368576458645149464442493633281919192018171713129.436.8775.9295.5474.9454.2391.848
Percentage of PrepaidExpenseAndOtherAssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets4.24.33.35.14.45.34.55.64.94.56.06.54.64.25.84.54.03.53.73.73.73.32.32.02.71.93.02.63.02.53.1

Property Plant And Equipment Gross

us-gaap:PropertyPlantAndEquipmentGross

us-gaap:PropertyPlantAndEquipmentGross


Property
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value11070383223104.5142.122
Percentage of PropertyPlantAndEquipmentGross100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets6.36.25.36.74.31.82.33.6

us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType

rare:ComputerEquipmentAndSoftware


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value8.1817.8177.3426.745
Percentage of PropertyPlantAndEquipmentGross7.411.119.220.5
Percentage of Assets0.50.71.01.4
Percentage of Assets rare:ComputerEquipmentAndSoftware0.00.00.00.0

rare:ResearchAndDevelopmentEquipment


Property
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value28179.8567.6962.1541.3020.7120.277
Percentage of PropertyPlantAndEquipmentGross25.625.425.823.49.312.715.813.1
Percentage of Assets1.61.61.41.60.40.20.40.5
Percentage of Assets rare:ResearchAndDevelopmentEquipment0.00.00.00.00.00.00.00.0

us-gaap:ConstructionInProgress


Property
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-31
Value17241.970.4290.0372.276
Percentage of PropertyPlantAndEquipmentGross15.934.55.21.30.222.2
Percentage of Assets1.02.10.30.10.00.4
Percentage of Assets us-gaap:ConstructionInProgress0.00.00.00.00.00.0

us-gaap:Land


Property
Period End2020-12-31
Value11
Percentage of PropertyPlantAndEquipmentGross10.6
Percentage of Assets0.7
Percentage of Assets us-gaap:Land0.0

us-gaap:LeaseholdImprovements


Property
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value39161515123.4662.1411.154
Percentage of PropertyPlantAndEquipmentGross35.524.041.146.053.833.947.454.4
Percentage of Assets2.21.52.23.12.30.61.11.9
Percentage of Assets us-gaap:LeaseholdImprovements0.00.00.00.00.00.00.00.0

us-gaap:OfficeEquipment


Property
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value5.0513.4963.3792.8732.5950.9440.5720.385
Percentage of PropertyPlantAndEquipmentGross4.65.08.88.811.29.212.718.1
Percentage of Assets0.30.30.50.60.50.20.30.6
Percentage of Assets us-gaap:OfficeEquipment0.00.00.00.00.00.00.00.0

us-gaap:OtherCapitalizedPropertyPlantAndEquipment


Property
Period End2020-12-31
Value0.554
Percentage of PropertyPlantAndEquipmentGross0.5
Percentage of Assets0.0
Percentage of Assets us-gaap:OtherCapitalizedPropertyPlantAndEquipment0.0

Accumulated Depreciation Depletion And Amortization Property Plant And Equipment

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment


Accumulated
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value372518106.1612.8651.4810.797
Percentage of AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.12.32.52.21.10.50.71.3

Property Plant And Equipment Net

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:PropertyPlantAndEquipmentNet


Property
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value1048773484847443125212019202021161616171817137.3736.2854.7723.5143.0332.6212.4971.7771.325
Percentage of PropertyPlantAndEquipmentNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets6.95.54.23.83.73.93.93.62.62.22.82.62.62.54.43.73.33.03.23.53.52.61.31.01.41.01.51.21.51.02.2

Intangible Assets Net Excluding Goodwill

us-gaap:IntangibleAssetsNetExcludingGoodwill

us-gaap:IntangibleAssetsNetExcludingGoodwill


Intangible
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value130131131131131129129129129129129130132137141
Percentage of IntangibleAssetsNetExcludingGoodwill100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets8.78.27.510.310.010.511.414.713.512.818.017.016.516.828.8

Operating Lease Right Of Use Asset

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:OperatingLeaseRightOfUseAsset


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value38384037373530313323
Percentage of OperatingLeaseRightOfUseAsset100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.62.42.33.02.82.92.73.63.52.3

Other Assets Noncurrent

us-gaap:OtherAssetsNoncurrent

us-gaap:OtherAssetsNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value128.9298.8125.0922.6274.8623.4713.1113.1812.663.5143.1993.2391.5741.3151.3451.7361.7621.8371.8681.4462.0630.5950.7340.790.7810.7740.8251.1290.552.648
Percentage of OtherAssetsNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.80.60.50.40.20.40.30.40.30.30.50.40.40.20.30.30.30.30.30.40.30.40.10.10.20.20.40.40.70.34.4

Accounts Payable Current

us-gaap:AccountsPayableCurrent

us-gaap:AccountsPayableCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value211512109.0141412138.74312128.198107.5698.8869.288118.3455.3646.6166.9546.0122.9424.422105.7554.8574.1613.593.4951.437
Percentage of AccountsPayableCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.41.00.70.90.71.21.11.50.91.31.71.11.30.91.82.12.41.51.01.31.41.10.50.73.01.62.52.02.22.02.4

Accrued Liabilities Current

us-gaap:AccruedLiabilitiesCurrent

us-gaap:AccruedLiabilitiesCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value9182108797167836959486258554961545042544324232420128.3987.5756.8315.2783.2384.406
Percentage of AccruedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets6.05.26.26.35.55.57.37.96.24.98.77.66.96.012.512.510.17.810.18.45.14.54.43.33.72.43.83.23.21.97.4

Contract With Customer Liability Current

us-gaap:ContractWithCustomerLiabilityCurrent

us-gaap:ContractWithCustomerLiabilityCurrent


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-302019-09-302019-06-302019-03-302018-06-302017-12-31
Value3.91225661021341450.0160.0550.0691.2445.986
Percentage of ContractWithCustomerLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.31.63.88.110.30.00.00.00.00.21.2

Liabilities Current

us-gaap:LiabilitiesCurrent

us-gaap:LiabilitiesCurrent


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value1271271892012191961039075667466665771646251605031292724231412118.9436.8115.921
Percentage of LiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets8.48.010.815.916.716.09.110.37.86.610.48.78.27.014.514.812.69.511.19.86.65.75.04.16.74.06.35.25.53.99.9

Operating Lease Liability Current

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OperatingLeaseLiabilityCurrent


Operating
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value8516000.07785000.07258000.07487000.07235000.07290000.06999000.05259000.0
Percentage of OperatingLeaseLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.50.60.60.60.60.80.70.5

Other Accrued Liabilities Current

us-gaap:OtherAccruedLiabilitiesCurrent

us-gaap:OtherAccruedLiabilitiesCurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value2625241614131816119.5569.0958.458.2517.3778.0926.6466.0684.7375.0854.034.6125.0471.4043.6522.030.910.6670.5050.2180.3090.16
Percentage of OtherAccruedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.81.61.41.31.11.11.71.91.20.91.31.11.00.91.61.51.20.90.90.81.01.00.30.60.60.30.30.20.10.20.3

Operating Lease Liability Noncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent


Operating
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value3836363429313222
Percentage of OperatingLeaseLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets2.22.92.82.82.63.53.42.3

Lessee Operating Lease Liability Payments Due Year Two

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearTwo


Lessee
Period End2020-12-31
Value11
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearTwo100.0
Percentage of Assets0.7

Lessee Operating Lease Liability Payments Due Year Three

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearThree


Lessee
Period End2020-12-31
Value12
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearThree100.0
Percentage of Assets0.7

Lessee Operating Lease Liability Payments Due Year Four

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFour


Lessee
Period End2020-12-31
Value10
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearFour100.0
Percentage of Assets0.6

Lessee Operating Lease Liability Payments Due Year Five

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueYearFive


Lessee
Period End2020-12-31
Value6247000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueYearFive100.0
Percentage of Assets0.4

Lessee Operating Lease Liability Payments Due After Year Five

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive


Lessee
Period End2020-12-31
Value3456000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive100.0
Percentage of Assets0.2

Operating Lease Liability

us-gaap:OperatingLeaseLiability

us-gaap:OperatingLeaseLiability


Operating
Period End2020-12-31
Value47
Percentage of OperatingLeaseLiability100.0
Percentage of Assets2.7

Lessee Operating Lease Liability Payments Due

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue


Lessee
Period End2020-12-31
Value55
Percentage of LesseeOperatingLeaseLiabilityPaymentsDue100.0
Percentage of Assets3.2

Lessee Operating Lease Liability Undiscounted Excess Amount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount


Lessee
Period End2020-12-31
Value8426000.0
Percentage of LesseeOperatingLeaseLiabilityUndiscountedExcessAmount100.0
Percentage of Assets0.5

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312012-12-312011-12-31
Value97210541154666695609653727819886608662703723383365429488473455443489531576319341184199153165-74.821-27.047-7.961
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets64.366.065.652.552.949.457.682.685.588.084.686.687.388.578.184.086.389.587.788.592.193.494.995.893.195.993.494.594.296.0-125.40.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AccumulatedOtherComprehensiveIncome


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-03-312016-12-312016-03-312015-12-312014-12-312013-12-31
Value0.2320.0560.6891.0131.284-1.545-0.147-0.0710.255-0.148-0.633-0.41-0.654-0.946-5.680.2310.9050.092-0.868-0.1740.011
Percentage of StockholdersEquity0.00.00.10.20.2-0.3-0.0-0.00.0-0.0-0.1-0.1-0.1-0.1-1.50.00.20.0-0.2-0.1-0.0
Percentage of Assets0.00.00.00.10.1-0.1-0.0-0.00.0-0.0-0.1-0.1-0.1-0.1-1.20.00.20.0-0.2-0.10.0
Percentage of Assets us-gaap:AccumulatedOtherComprehensiveIncome0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312012-12-312011-12-31
Value28502810277322602220216220862066204520131639160515591526122110038163240.0080.191
Percentage of StockholdersEquity293.2266.5240.2339.3319.3355.0319.2284.1249.5227.1269.3242.3221.6211.0318.6211.7153.8175.3-0.0-2.4
Percentage of Assets188.4175.9157.6178.2169.0175.4183.8234.8213.3199.8227.9209.8193.5186.8249.0185.6145.9163.70.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value0.0680.0670.0670.0610.060.0590.0580.0580.0580.0570.0510.0510.050.050.0440.0410.0390.0320.0040.0030.003
Percentage of StockholdersEquity0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0-0.0-0.0-0.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value-1878.145-1755.717-1619.576-1595.565-1526.72-1552.035-1433.01-1339.205-1226.211-1127.039-1030.283-942.457-855.147-802.419-832.672-530.533-284.659-139.041-74.836-27.058-8.155
Percentage of StockholdersEquity-193.2-166.5-140.3-239.5-219.5-254.8-219.2-184.1-149.6-127.1-169.2-142.2-121.5-110.9-217.2-111.9-53.6-75.2100.0100.0102.4
Percentage of Assets-124.2-109.9-92.0-125.8-116.2-125.9-126.2-152.2-127.9-111.8-143.2-123.2-106.1-98.2-169.7-98.1-50.9-70.2-125.50.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value0.0680.0670.0670.0610.060.0590.0580.0580.0580.0570.0510.0510.050.050.0440.0420.0420.0420.0410.040.0390.0390.0390.0390.0360.0360.0320.0320.030.030.004
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStockValue us-gaap:CounterpartyName

rare:SolidBiosciencesInc


Common
Period End2020-10-31
Value26
Percentage of CommonStockValue0.0
Percentage of Assets0.0
Percentage of Assets rare:SolidBiosciencesInc0.0

Additional Paid In Capital

us-gaap:AdditionalPaidInCapital

us-gaap:AdditionalPaidInCapital


Additional
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value2850281027732260222021622086206620452013163916051559152612211123110510871003915837827816806509501324
Percentage of AdditionalPaidInCapital100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets188.4175.9157.6178.2169.0175.4183.8234.8213.3199.8227.9209.8193.5186.8249.0258.3222.2199.2185.6177.6173.9157.8145.9133.9148.6141.0163.7

Retained Earnings Accumulated Deficit

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:RetainedEarningsAccumulatedDeficit


Retained
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value-1878100000.0-1755700000.0-1619600000.0-1595600000.0-1526700000.0-1552000000.0-1433000000.0-1339200000.0-1226200000.0-1127000000.0-1030300000.0-942460000.0-855150000.0-802420000.0-832670000.0-750940000.0-671710000.0-598820000.0-530530000.0-459250000.0-394340000.0-337420000.0-284660000.0-229440000.0-190210000.0-160420000.0-139040000.0-122300000.0-106450000.0-92869000.0-74836000.0
Percentage of RetainedEarningsAccumulatedDeficit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets-124.2-109.9-92.0-125.8-116.2-125.9-126.2-152.2-127.9-111.8-143.2-123.2-106.1-98.2-169.7-172.6-135.0-109.7-98.1-89.1-81.8-64.4-50.9-38.1-55.5-45.1-70.2-58.0-65.5-53.8-125.5

Accumulated Other Comprehensive Income Loss Net Of Tax

us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax

us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax


Accumulated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value232000.056000.0689000.01013000.01284000.0-1545000.0-147000.0-71000.0255000.0-148000.0-633000.0-410000.0-654000.0-946000.0-5680000.0-7404000.0-4223000.0231000.0905000.012000.0252000.092000.0-868000.0-39000.0-209000.0-94000.0-174000.0-118000.0-48000.0-46000.011000.0
Percentage of AccumulatedOtherComprehensiveIncomeLossNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.10.1-0.1-0.0-0.00.0-0.0-0.1-0.1-0.1-0.1-1.2-1.7-0.80.00.20.00.10.0-0.2-0.0-0.1-0.0-0.1-0.1-0.0-0.00.0

Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue


Adjustments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value2724222022201919222022201918
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Adjustments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value2724222022201919222022201918
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value-65.356-159.346-62.452-61.96787-95.152-72.039-88.506-89.063-95.775-55.853-69.157-76.078-89.478-81.823-61.993-11.03-10.529-8.336-6.747-8.387-6.293
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-75.1-160.3-68.2-76.1141.6-262.1-202.4-343.0-368.8-527.0-343.5-587.9-594.6-838.0-3389.5-31309.60.00.00.00.00.00.0

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value-41.246-182.42497-95.758-86.139-95.1256779-58.426-101.1937316-52.069-71.0285729-13.545-27.476-65.398-0.787-42.96-15.1
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-47.4-183.5106.9-117.5-139.6-262.0189.0307.4-241.9-556.9452.4137.8-407.0-665.22377.415044.40.00.00.00.00.00.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value12124891935553150.9049.342353122513286641.333600.011210.0760.0560.001
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax14.512.7535.023.558.0153.2886.33.538.71945.975.3212.7102.92682.62669.4673.20.00.00.00.00.00.0

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-93.526-329.892526-138.15337-135.285311-8.76-137.97915630-27.898-115.87512640-30.344-68.751-2.839
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-107.5-331.9574.6-169.660.7-372.6873.8-34.0-571.4860.9185.1-237.2-905.71181.61672.2-15325.30.00.0

Depreciation Depletion And Amortization

us-gaap:DepreciationDepletionAndAmortization

us-gaap:DepreciationDepletionAndAmortization


Depreciation
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value3.1213.3673.1333.0923.1842.8522.1692.1452.1062.1192.9434.3556.086.162.5141.0951.0551.1611.1571.0310.6920.5440.480.4410.2620.2010.2120.1940.1610.1170.1120.1050.1030.124
Percentage of DepreciationDepletionAndAmortization100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Increase Decrease In Accounts Receivable

us-gaap:IncreaseDecreaseInAccountsReceivable

us-gaap:IncreaseDecreaseInAccountsReceivable


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-0.3241.993-4.71412-14.455-3.59.7022.2415.2622.8993.6-8.2713-1.501
Percentage of IncreaseDecreaseInAccountsReceivable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Increase Decrease In Inventories

us-gaap:IncreaseDecreaseInInventories

us-gaap:IncreaseDecreaseInInventories


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value2648000.0-474000.0-1289000.03156000.0-372000.0-149000.0-2153000.0564000.02393000.03647000.0484000.02214000.01274000.01311000.0
Percentage of IncreaseDecreaseInInventories100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value-65.356-159.346-62.452-61.96787-95.152-72.039-88.506-89.063-95.775-55.853-69.157-76.078-89.478-81.823-61.993-11.03-10.529-8.336-6.747-8.387-6.293
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-75.1-160.3-68.2-76.1141.6-262.1-202.4-343.0-368.8-527.0-343.5-587.9-594.6-838.0-3389.5-31309.60.00.00.00.00.00.0

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-122.428-136.141-24.011-68.84525-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830-81.731-79.227-72.891-68.29-71.287-64.907-56.923-52.757-55.22-39.232-29.787-21.379-16.738-15.849-13.585-13.63-11.317-8.428-8.59-6.735
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.8-137.0-26.2-84.541.0-327.8-263.5-438.0-410.7-532.4-540.1-742.2-412.1283.3-3385.7-40013.60.00.0-1425740.0-58474.8-334841.20.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-122.428-136.141-24.011-68.84525-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.8-137.0-26.2-84.541.0-327.8-263.5-438.0-410.7-532.4-540.1-742.2-412.1283.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Profit Loss

us-gaap:ProfitLoss

us-gaap:ProfitLoss


Profit
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-122.428-136.141-24.011-68.84525-119.025-93.805-112.994-99.172-96.756-87.826-87.31-52.72830
Percentage of ProfitLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-140.8-137.0-26.2-84.541.0-327.8-263.5-438.0-410.7-532.4-540.1-742.2-412.1283.3

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value-41.246-182.42497-95.758-86.139-95.1256779-58.426-101.1937316-52.069-71.0285729-13.545-27.476-65.398-0.787-42.96-15.1
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-47.4-183.5106.9-117.5-139.6-262.0189.0307.4-241.9-556.9452.4137.8-407.0-665.22377.415044.40.00.00.00.00.00.0

Payments To Acquire Property Plant And Equipment

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value2016213.784.08314115.0335.243.0591.1921.0321.3770.4750.8991.0330.3760.4850.6663.0015.0441.4771.9231.9780.5950.4590.4530.4390.6880.5690.1290.203-0.1020.177
Percentage of PaymentsToAcquirePropertyPlantAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302014-09-302014-06-302014-03-312013-09-302013-06-302013-03-31
Value12124891935553150.9049.342353122513286641.333600.011210.0760.0560.001
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax14.512.7535.023.558.0153.2886.33.538.71945.975.3212.7102.92682.62669.4673.20.00.00.00.00.00.0

Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice


Share
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value62.9962.5162.4662.7561.8556.3616.153.410.470.31
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Deferred Tax Assets Net

us-gaap:DeferredTaxAssetsNet

us-gaap:DeferredTaxAssetsNet


Deferred
Period End2020-12-312019-12-312016-12-312015-12-312014-12-312013-12-31
Value337.6620.00.00.00.0
Percentage of DeferredTaxAssetsNet100.0100.00.00.00.00.0

Unrecognized Tax Benefits

us-gaap:UnrecognizedTaxBenefits

us-gaap:UnrecognizedTaxBenefits


Unrecognized
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value4639332813247.2753.7251.5510.324
Percentage of UnrecognizedTaxBenefits100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Deferred Tax Assets Valuation Allowance

us-gaap:DeferredTaxAssetsValuationAllowance

us-gaap:DeferredTaxAssetsValuationAllowance


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value5614863613042121095125
Percentage of DeferredTaxAssetsValuationAllowance100.0100.0100.0100.0100.0100.0100.0100.0

rare:AcquisitionOfInvestmentInCommonStock us-gaap:CounterpartyName, us-gaap:StatementEquityComponents

rare:AcquisitionOfInvestmentInCommonStock

rare:SolidBiosciencesInc, us-gaap:CommonStock


Acquisition
Period End2020-12-31
Value26
Percentage of AcquisitionOfInvestmentInCommonStock100.0

rare:AllocatedShareBasedCompensationExpenseNetOfCapitalizedInventoryCost

rare:AllocatedShareBasedCompensationExpenseNetOfCapitalizedInventoryCost


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value27242220222019192220
Percentage of AllocatedShareBasedCompensationExpenseNetOfCapitalizedInventoryCost100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:AnnualFeesPayable dei:LegalEntity, us-gaap:TypeOfArrangement

rare:AnnualFeesPayable

rare:REGENXBIOIncorporated, rare:LicenseAgreement


Annual
Period End2020-12-312020-03-31
Value0100000.0
Percentage of AnnualFeesPayable0.0100.0

rare:ChangeInFairValueOfAdditionalCommonStock us-gaap:TypeOfArrangement

rare:ChangeInFairValueOfAdditionalCommonStock

rare:ArcturusResearchCollaborationAndLicenseAgreement


Change
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value0.00.0221.10.00.21.00.0
Percentage of ChangeInFairValueOfAdditionalCommonStock0.00.0100.0100.00.0100.0100.00.0

rare:CollaborativeArrangementsEffectiveReductionOfExpense us-gaap:TypeOfArrangement

rare:CollaborativeArrangementsEffectiveReductionOfExpense

rare:KyowaKirinCollaboration


Collaborative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value12131210111213121112101013
Percentage of CollaborativeArrangementsEffectiveReductionOfExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:CollaborativeArrangementsEffectiveReductionOfExpenseInResearchAndDevelopmentExpenses us-gaap:TypeOfArrangement

rare:CollaborativeArrangementsEffectiveReductionOfExpenseInResearchAndDevelopmentExpenses

rare:KyowaKirinCollaboration


Collaborative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value5.1716.1855.6625.1565.1685.497.1917.1245.8957.0996.9727.6129.42
Percentage of CollaborativeArrangementsEffectiveReductionOfExpenseInResearchAndDevelopmentExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:CollaborativeArrangementsEffectiveReductionOfExpenseInSellingGeneralAndAdministrativeExpenses us-gaap:TypeOfArrangement

rare:CollaborativeArrangementsEffectiveReductionOfExpenseInSellingGeneralAndAdministrativeExpenses

rare:KyowaKirinCollaboration


Collaborative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-30
Value7.5767.4956.6775.4925.9657.0525.8195.6335.1635.2133.512.8684.068
Percentage of CollaborativeArrangementsEffectiveReductionOfExpenseInSellingGeneralAndAdministrativeExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:ContractWithCustomerLiabilityAdditionsDuringPeriod

rare:ContractWithCustomerLiabilityAdditionsDuringPeriod


Contract
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312020-03-302019-12-312019-09-302019-06-302019-03-312019-03-302018-12-312018-09-302018-06-302018-03-31
Value0.7791.271-1.167-0.866-8.472145-145.2830.0520.10.0690.2830.2831.5643.6148.9439.934
Percentage of ContractWithCustomerLiabilityAdditionsDuringPeriod100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:ContractWithCustomerLiabilityDeductionsDuringPeriod

rare:ContractWithCustomerLiabilityDeductionsDuringPeriod


Contract
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value2142-37.497-32.8660.0360.0610.0553.3310.3230.632113.111
Percentage of ContractWithCustomerLiabilityDeductionsDuringPeriod100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:CostOfSales

rare:CostOfSales


Cost
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value3136000.05188000.05481000.02348000.01803000.0-3503000.05107000.02683000.0766000.0452000.0507000.0273000.0
Percentage of CostOfSales100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:DiscountOnLetterOfCreditOnSuccessfulPaymentOfLeaseAmount us-gaap:LeaseArrangementType, us-gaap:StatementScenario

rare:DiscountOnLetterOfCreditOnSuccessfulPaymentOfLeaseAmount

rare:BrisbaneOfficeFacility, us-gaap:ScenarioForecast


Discount
Period End2021-05-31
Value700000.0
Percentage of DiscountOnLetterOfCreditOnSuccessfulPaymentOfLeaseAmount100.0

rare:EstimatedReimbursementOfDeliveringLicenseAndTechnologyServices us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

rare:EstimatedReimbursementOfDeliveringLicenseAndTechnologyServices

rare:DaiichiSankyoCoLtd, rare:LicenseAndTechnologyAccessAgreement


Estimated
Period End2021-06-302021-03-312020-12-31
Value200000.05700000.0100000.0
Percentage of EstimatedReimbursementOfDeliveringLicenseAndTechnologyServices100.0100.0100.0

rare:IncreaseDecreaseInAccountsPayableAccruedLiabilitiesAndOtherOperatingLiabilities

rare:IncreaseDecreaseInAccountsPayableAccruedLiabilitiesAndOtherOperatingLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value12-23.6022411-3.45-5.3839.269116.005-13.081
Percentage of IncreaseDecreaseInAccountsPayableAccruedLiabilitiesAndOtherOperatingLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:IncreaseDecreaseInContractLiabilities

rare:IncreaseDecreaseInContractLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value-21.177-41.479-36.33-32.0-10.385145
Percentage of IncreaseDecreaseInContractLiabilities100.0100.0100.0100.0100.0100.0

rare:IncreaseDecreaseInLeaseLiabilities

rare:IncreaseDecreaseInLeaseLiabilities


Increase
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value0.921.1695.511-1.451116.812
Percentage of IncreaseDecreaseInLeaseLiabilities100.0100.0100.0100.0100.0100.0

rare:IncreaseDecreaseInRightOFUseAssets

rare:IncreaseDecreaseInRightOFUseAssets


Increase
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value0.5081.2315.522-1.619106.88
Percentage of IncreaseDecreaseInRightOFUseAssets100.0100.0100.0100.0100.0100.0

rare:IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax

rare:IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax


Issuance
Period End2021-06-302021-03-312020-09-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value121219151.2090.9043.8143.8971.8129.187133.642
Percentage of IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Issuance
Period End2021-06-302021-03-312020-09-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value121219151.2090.9043.8133.8971.8129.186133.642
Percentage of IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:CommonStock


Issuance
Period End2021-06-302020-09-302020-06-302019-12-312019-09-302019-06-302018-12-312018-09-30
Value0.0010.0010.0010.00.00.0010.00.001
Percentage of IssuanceOfCommonStockUnderEquityPlanAwardsNetOfTax0.00.00.00.00.00.00.00.0

rare:IssuanceOfCommonStockUponExerciseOfWarrantsAndUnderEquityPlanAwardsNetOfTax

rare:IssuanceOfCommonStockUponExerciseOfWarrantsAndUnderEquityPlanAwardsNetOfTax


Issuance
Period End2020-12-312020-09-302020-06-302020-03-31
Value5419150.38
Percentage of IssuanceOfCommonStockUponExerciseOfWarrantsAndUnderEquityPlanAwardsNetOfTax100.0100.0100.0100.0

rare:IssuanceOfCommonStockUponExerciseOfWarrantsAndUnderEquityPlanAwardsNetOfTax us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Issuance
Period End2020-12-312020-09-302020-06-302020-03-31
Value5419150.38
Percentage of IssuanceOfCommonStockUponExerciseOfWarrantsAndUnderEquityPlanAwardsNetOfTax100.0100.0100.0100.0

rare:IssuanceOfCommonStockValueInConnectionWithLicenseAgreement

rare:IssuanceOfCommonStockValueInConnectionWithLicenseAgreement


Issuance
Period End2020-12-312020-09-302020-06-302020-03-31
Value0.00.00.055
Percentage of IssuanceOfCommonStockValueInConnectionWithLicenseAgreement0.00.00.0100.0

rare:IssuanceOfCommonStockValueInConnectionWithLicenseAgreement us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

rare:DaiichiSankyoCoLtd, rare:StockPurchaseAgreement


Issuance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value0.0550.00.00.055
Percentage of IssuanceOfCommonStockValueInConnectionWithLicenseAgreement0.00.00.00.00.0100.1

rare:IssuanceOfCommonStockValueInConnectionWithLicenseAgreement us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Issuance
Period End2020-12-312020-09-302020-06-302020-03-31
Value0.00.00.055
Percentage of IssuanceOfCommonStockValueInConnectionWithLicenseAgreement0.00.00.0100.0

us-gaap:CommonStock


Issuance
Period End2020-12-312020-09-302020-06-302020-03-31
Value0.00.00.00.001
Percentage of IssuanceOfCommonStockValueInConnectionWithLicenseAgreement0.00.00.00.0

rare:MilestonePaymentsReceived dei:LegalEntity, us-gaap:TypeOfArrangement

rare:MilestonePaymentsReceived

rare:BayerHealthCareLLC, rare:ResearchDevelopmentAndCommercializeAAVGeneTherapyProductsAgreement


Milestone
Period End2021-06-302021-03-312020-12-31
Value0.0150.0
Percentage of MilestonePaymentsReceived0.0100.00.0

rare:NonCashCollaborationRoyaltyRevenue

rare:NonCashCollaborationRoyaltyRevenue


Non
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value4.6893.8723.5673.3313.4822.615
Percentage of NonCashCollaborationRoyaltyRevenue100.0100.0100.0100.0100.0100.0

rare:NonCashInterestExpenseOnLiabilityRelatedToSaleOfFutureRoyalties

rare:NonCashInterestExpenseOnLiabilityRelatedToSaleOfFutureRoyalties


Non
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value8.5178.4188.1988.5828.4298.082
Percentage of NonCashInterestExpenseOnLiabilityRelatedToSaleOfFutureRoyalties100.0100.0100.0100.0100.0100.0

rare:OptionToSellCommonStockAggregateOfferingPrice us-gaap:SubsidiarySaleOfStock

rare:OptionToSellCommonStockAggregateOfferingPrice

rare:OpenMarketSale


Option
Period End2021-05-31
Value350
Percentage of OptionToSellCommonStockAggregateOfferingPrice100.0

rare:PaymentForPurchaseOfCommonStock us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

rare:PaymentForPurchaseOfCommonStock

rare:SolidBiosciencesInc, rare:CollaborationAgreement


Payment
Period End2020-10-31
Value40
Percentage of PaymentForPurchaseOfCommonStock100.0

rare:PaymentForPurchaseOfCommonStock us-gaap:SubsequentEventType, us-gaap:TypeOfArrangement

us-gaap:SubsequentEvent, rare:CollaborationAgreement


Payment
Period End2020-10-30
Value40
Percentage of PaymentForPurchaseOfCommonStock0.0

rare:PaymentsMadeUnderAgreement us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType

rare:PaymentsMadeUnderAgreement

rare:MereoBioPharma3Limited, rare:LicenseAndCollaborationAgreement


Payments
Period End2021-01-31
Value50
Percentage of PaymentsMadeUnderAgreement100.0

rare:PaymentsMadeUnderAgreement us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:SubsequentEventType

rare:MereoBioPharma3Limited, rare:LicenseAndCollaborationAgreement, us-gaap:SubsequentEvent


Payments
Period End2021-01-31
Value50
Percentage of PaymentsMadeUnderAgreement100.0

rare:PremiumFromStockPurchaseAgreement us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

rare:PremiumFromStockPurchaseAgreement

rare:DaiichiSankyoCoLtd, rare:LicenseAndTechnologyAccessAgreement


Premium
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value0.0190.00.00.019
Percentage of PremiumFromStockPurchaseAgreement0.0100.00.00.00.0100.0

rare:DaiichiSankyoCoLtd, rare:StockPurchaseAgreement


Premium
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value0.0190.00.00.019
Percentage of PremiumFromStockPurchaseAgreement0.0100.00.00.00.0100.0

rare:ProceedsFromIssuanceOfCommonStockAtMarketOffering

rare:ProceedsFromIssuanceOfCommonStockAtMarketOffering


Proceeds
Period End2020-12-312020-09-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-31
Value0.00.00.00.05.523191015-0.01911640.00.0256745
Percentage of ProceedsFromIssuanceOfCommonStockAtMarketOffering0.00.00.00.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0100.0

rare:ProceedsFromIssuanceOfCommonStockInConnectionWithLicenseAgreement

rare:ProceedsFromIssuanceOfCommonStockInConnectionWithLicenseAgreement


Proceeds
Period End2020-12-312020-09-302020-06-302020-03-31
Value0.00.00.055
Percentage of ProceedsFromIssuanceOfCommonStockInConnectionWithLicenseAgreement0.00.00.0100.0

rare:ProfitLossSharingPercentageOnCommercializingProducts us-gaap:StatementGeographical, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

rare:ProfitLossSharingPercentageOnCommercializingProducts

rare:UnitedStatesAndCanada, us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Profit
Period End2021-06-302021-03-312020-12-31
Value050.00
Percentage of ProfitLossSharingPercentageOnCommercializingProducts0.0100.00.0

rare:ProfitLossSharingPercentageOnNetSales us-gaap:StatementScenario, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

rare:ProfitLossSharingPercentageOnNetSales

srt:ScenarioForecast, us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Profit
Period End2023-01-01
Value0.3
Percentage of ProfitLossSharingPercentageOnNetSales100.0

rare:StockIssuedDuringPeriodValueAtMarketOffering

rare:StockIssuedDuringPeriodValueAtMarketOffering


Stock
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value0.00.0200.00.05.5231910150.011
Percentage of StockIssuedDuringPeriodValueAtMarketOffering0.00.0100.00.00.0100.0100.0100.0100.00.0100.0

rare:StockIssuedDuringPeriodValueAtMarketOffering us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stock
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value0.00.0200.00.05.5231910150.011
Percentage of StockIssuedDuringPeriodValueAtMarketOffering0.00.0100.00.00.0100.0100.0100.0100.00.0100.0

rare:TransactionPriceOfLicenseAgreement us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

rare:TransactionPriceOfLicenseAgreement

rare:DaiichiSankyoCoLtd, rare:LicenseAndTechnologyAccessAgreement


Transaction
Period End2021-06-302021-03-312020-12-31
Value0.21830.1
Percentage of TransactionPriceOfLicenseAgreement100.0100.0100.0

rare:TransferOfFairValueOnAdditionalExerciseOfOptions us-gaap:TypeOfArrangement

rare:TransferOfFairValueOnAdditionalExerciseOfOptions

rare:ArcturusResearchCollaborationAndLicenseAgreement


Transfer
Period End2020-12-31
Value0
Percentage of TransferOfFairValueOnAdditionalExerciseOfOptions0.0

rare:UpfrontPaymentForInProcessResearchAndDevelopmentExpense us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType

rare:UpfrontPaymentForInProcessResearchAndDevelopmentExpense

rare:MereoBioPharma3Limited, rare:LicenseAndCollaborationAgreement


Upfront
Period End2021-03-31
Value50
Percentage of UpfrontPaymentForInProcessResearchAndDevelopmentExpense100.0

us-gaap:AccretionAmortizationOfDiscountsAndPremiumsInvestments

us-gaap:AccretionAmortizationOfDiscountsAndPremiumsInvestments


Accretion
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value-1571000.0-940000.0-631000.0-366000.0-150000.0299000.01283000.01971000.02121000.0839000.0809000.0919000.01152000.0-239000.0-255000.0-400000.0-502000.0-549000.0-612000.0-1015000.0-1387000.0-1828000.0-1937000.0-1467000.0-1268000.0-965000.0-1156000.0-1048000.0-917000.0-479000.0-441000.0
Percentage of AccretionAmortizationOfDiscountsAndPremiumsInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ContractWithCustomerLiabilityRevenueRecognized us-gaap:CounterpartyName, us-gaap:ProductOrService, us-gaap:TypeOfArrangement

us-gaap:ContractWithCustomerLiabilityRevenueRecognized

rare:DaiichiSankyoCoLtd, rare:LicenseAgreement, rare:LicenseAndTechnologyAccessAgreement


Contract
Period End2021-06-302021-03-31
Value21132
Percentage of ContractWithCustomerLiabilityRevenueRecognized100.0100.0

us-gaap:DeferredRevenueRevenueRecognized1 us-gaap:CounterpartyName

us-gaap:DeferredRevenueRevenueRecognized1

rare:DaiichiSankyoCoLtd


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-30
Value2242373218
Percentage of DeferredRevenueRevenueRecognized1100.0100.0100.0100.0100.0

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations


Effect
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value448000.0-771000.0880000.0437000.0425000.0-623000.0337000.0-472000.0168000.0-198000.0145000.030000.0-896000.0249000.0361000.0528000.0
Percentage of EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:EquitySecuritiesFvNiGainLoss

us-gaap:EquitySecuritiesFvNiGainLoss


Equity
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-30
Value-31.046-20.61979-11.52957.6681.4192.1669.828
Percentage of EquitySecuritiesFvNiGainLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FairValueAdjustmentOfWarrants us-gaap:ShortTermDebtType

us-gaap:FairValueAdjustmentOfWarrants

rare:ConvertiblePromissoryNote


Fair
Period End2021-06-302021-03-31
Value0600000.0
Percentage of FairValueAdjustmentOfWarrants0.0100.0

us-gaap:FairValueOptionChangesInFairValueGainLoss1 us-gaap:CounterpartyName, us-gaap:StatementEquityComponents

us-gaap:FairValueOptionChangesInFairValueGainLoss1

rare:SolidBiosciencesInc, us-gaap:CommonStock


Fair
Period End2021-06-302021-03-312020-12-31
Value-14.634-16.04332
Percentage of FairValueOptionChangesInFairValueGainLoss1100.0100.0100.0

us-gaap:FairValueOptionChangesInFairValueGainLoss1 us-gaap:StatementEquityComponents, us-gaap:TypeOfArrangement

us-gaap:CommonStock, rare:ArcturusResearchCollaborationAndLicenseAgreement


Fair
Period End2021-06-302021-03-312020-12-312020-09-30
Value-16.412-4.57646-11.52
Percentage of FairValueOptionChangesInFairValueGainLoss1112.128.5143.40.0

us-gaap:FairValueOptionChangesInFairValueGainLoss1 us-gaap:TypeOfArrangement

rare:ArcturusResearchCollaborationAndLicenseAgreement


Fair
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value-16.412-4.57646-11.52966.51.42.08.80.0
Percentage of FairValueOptionChangesInFairValueGainLoss1112.128.5143.40.00.00.00.00.00.00.0

us-gaap:ForeignCurrencyTransactionGainLossBeforeTax

us-gaap:ForeignCurrencyTransactionGainLossBeforeTax


Foreign
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value388000.0-142000.0449000.0-474000.0237000.0-358000.022000.0-589000.0544000.0-7000.0-1073000.0-4773000.0-1413000.03827000.03956000.0648000.0
Percentage of ForeignCurrencyTransactionGainLossBeforeTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-302013-03-31
Value-1.65410-15.2096.325-8.96151.2622.6891.9062.359-6.099-2.375175.0634.098-0.2910.461-0.931.3141.2790.5264.0280.7362.8942.5530.9480.3820.6020.7062.3910.2060.0990.5120.776
Percentage of IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InvestmentIncomeInterest

us-gaap:InvestmentIncomeInterest


Investment
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-30
Value0.4410.6390.9841.3381.7972.9192.773.3194.0633.0862.6272.732.4481.7370.7241.1171.1511.0820.9120.9220.9710.9840.9180.6730.4560.2730.1950.1710.1490.0930.0590.068
Percentage of InvestmentIncomeInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax

us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-30
Value103000.0-285000.0321000.0374000.089000.0-49000.0102000.0-234000.026000.0129000.0-300000.061000.0225000.0-289000.0-1733000.0-3326000.0-4403000.0-648000.01339000.0-28000.011000.0
Percentage of OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax

us-gaap:OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-312013-09-302013-06-30
Value73000.0-348000.0-645000.0-645000.02740000.0-1349000.0-178000.0-92000.0377000.0356000.077000.0183000.067000.0-249000.0-33000.0145000.0-51000.0-26000.0-446000.0-212000.0149000.0960000.0-829000.0170000.0-115000.080000.0-56000.0-70000.0-2000.0-57000.025000.063000.0-66000.0
Percentage of OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OtherNoncashIncomeExpense

us-gaap:OtherNoncashIncomeExpense


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302018-12-312018-09-30
Value-186000.0-325000.0-1195000.062000.0429000.0-463000.0-337000.0-352000.011000.00
Percentage of OtherNoncashIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.00.0

us-gaap:PaymentsToAcquireAvailableForSaleSecurities

us-gaap:PaymentsToAcquireAvailableForSaleSecurities


Payments
Period End2020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value192171285821492002609.74791147260-0.00323119871308810411814623416577483141870.897
Percentage of PaymentsToAcquireAvailableForSaleSecurities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PaymentsToAcquireAvailableForSaleSecuritiesDebt

us-gaap:PaymentsToAcquireAvailableForSaleSecuritiesDebt


Payments
Period End2021-06-302021-03-312020-06-302020-03-31
Value259405171285
Percentage of PaymentsToAcquireAvailableForSaleSecuritiesDebt100.0100.0100.0100.0

us-gaap:PaymentsToAcquireEquityMethodInvestments

us-gaap:PaymentsToAcquireEquityMethodInvestments


Payments
Period End2020-12-312020-09-302019-12-312019-09-30
Value260.620.00.0
Percentage of PaymentsToAcquireEquityMethodInvestments100.0100.00.00.0

us-gaap:ProceedsFromIssuanceOfCommonStock us-gaap:SubsidiarySaleOfStock

us-gaap:ProceedsFromIssuanceOfCommonStock

rare:UnderwrittenPublicOffering


Proceeds
Period End2020-10-312019-02-282018-01-31
Value435330271
Percentage of ProceedsFromIssuanceOfCommonStock100.0100.0100.0

us-gaap:ProceedsFromIssuanceOfCommonStock us-gaap:TypeOfArrangement

rare:ArcturusResearchCollaborationAndLicenseAgreement


Proceeds
Period End2020-12-31
Value79
Percentage of ProceedsFromIssuanceOfCommonStock0.0

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-31
Value12125419150.381.2090.9043.8193.8971.8129.187133.6425.0391.3331.5011.3784.163.385-0.0250.3140.909
Percentage of ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities

us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value1822242229386187153221161140841055160704889647710391131904947622915142312
Percentage of ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ProceedsFromPaymentsForOtherFinancingActivities

us-gaap:ProceedsFromPaymentsForOtherFinancingActivities


Proceeds
Period End2021-06-302021-03-312020-06-302020-03-31
Value-114000.0-112000.0-58000.0-33000.0
Percentage of ProceedsFromPaymentsForOtherFinancingActivities100.0100.0100.0100.0

us-gaap:ProceedsFromSaleOfAvailableForSaleSecurities

us-gaap:ProceedsFromSaleOfAvailableForSaleSecurities


Proceeds
Period End2020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-31
Value1112167.618120.0220.02.7011306.09.227124639421126437.497121.999
Percentage of ProceedsFromSaleOfAvailableForSaleSecurities100.0100.0100.0100.0100.00.0100.00.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt

us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt


Proceeds
Period End2021-06-302021-03-312020-06-302020-03-31
Value55141216
Percentage of ProceedsFromSaleOfAvailableForSaleSecuritiesDebt100.0100.0100.0100.0

us-gaap:RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

us-gaap:RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer

rare:DaiichiSankyoCoLtd, rare:LicenseAndTechnologyAccessAgreement


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-31
Value0.01250.00.00.0125
Percentage of RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer0.0100.00.00.00.0100.0

rare:DaiichiSankyoCoLtd, rare:SublicenseAgreement


Revenue
Period End2021-06-302021-03-312020-12-312020-09-30
Value0.08.00.00.0
Percentage of RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer0.06.40.00.0

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability


Right
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value9.733-3.9357.3970.0138.28
Percentage of RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability100.0100.0100.00.0100.0100.0

us-gaap:UnrealizedGainLossOnInvestments us-gaap:CounterpartyName, us-gaap:StatementEquityComponents

us-gaap:UnrealizedGainLossOnInvestments

rare:SolidBiosciencesInc, us-gaap:CommonStock


Unrealized
Period End2021-06-30
Value-14.6
Percentage of UnrealizedGainLossOnInvestments100.0

us-gaap:UnrealizedGainLossOnInvestments us-gaap:StatementEquityComponents, us-gaap:TypeOfArrangement

us-gaap:CommonStock, rare:ArcturusResearchCollaborationAndLicenseAgreement


Unrealized
Period End2021-06-302021-03-312020-09-302020-06-302020-03-31
Value-16.4-4.6-11.5957.7
Percentage of UnrealizedGainLossOnInvestments112.30.00.00.00.0

rare:ContractLiabilitiesCurrent

rare:ContractLiabilitiesCurrent


Contract
Period End2021-06-302021-03-312020-12-312020-09-30
Value3.9121959102
Percentage of ContractLiabilitiesCurrent100.0100.0100.0100.0

rare:ContractLiabilitiesNoncurrent

rare:ContractLiabilitiesNoncurrent


Contract
Period End2021-03-312020-12-31
Value5868000.07349000.0
Percentage of ContractLiabilitiesNoncurrent100.0100.0

rare:DeferredTaxAssetFixedAssetsAndIntangibles

rare:DeferredTaxAssetFixedAssetsAndIntangibles


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value7242000.03870000.02820000.01194000.03014000.04442000.0455000.065000.0
Percentage of DeferredTaxAssetFixedAssetsAndIntangibles100.0100.0100.0100.0100.0100.0100.0100.0

rare:DeferredTaxAssetsLiabilityRelatedToSaleOfFutureRoyalties

rare:DeferredTaxAssetsLiabilityRelatedToSaleOfFutureRoyalties


Deferred
Period End2020-12-312019-12-31
Value8681
Percentage of DeferredTaxAssetsLiabilityRelatedToSaleOfFutureRoyalties100.0100.0

rare:DeferredTaxAssetsStockOption

rare:DeferredTaxAssetsStockOption


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value39402921166.681.058
Percentage of DeferredTaxAssetsStockOption100.0100.0100.0100.0100.0100.0100.0

rare:EquityInvestmentsNoncurrent

rare:EquityInvestmentsNoncurrent


Equity
Period End2021-06-302021-03-312020-12-312019-12-31
Value10313415527
Percentage of EquityInvestmentsNoncurrent100.0100.0100.0100.0

rare:FutureContingentMilestonePayments us-gaap:RelatedPartyTransactionsByRelatedParty, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:SubsequentEventType

rare:FutureContingentMilestonePayments

rare:MereoBioPharma3Limited, rare:LicenseAndCollaborationAgreement, us-gaap:SubsequentEvent


Future
Period End2021-01-31
Value254
Percentage of FutureContingentMilestonePayments100.0

rare:InvestmentInEquitySecurities

rare:InvestmentInEquitySecurities


Investment
Period End2020-09-302020-06-302020-03-312019-12-31
Value1291403527
Percentage of InvestmentInEquitySecurities100.0100.0100.0100.0

rare:LiabilityRelatedToSaleOfFutureRoyalties

rare:LiabilityRelatedToSaleOfFutureRoyalties


Liability
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-12-31
Value3443403353313253203150.0
Percentage of LiabilityRelatedToSaleOfFutureRoyalties100.0100.0100.0100.0100.0100.0100.00.0

rare:OperatingAndFinanceLeaseLiability

rare:OperatingAndFinanceLeaseLiability


Operating
Period End2020-12-31
Value48
Percentage of OperatingAndFinanceLeaseLiability100.0

rare:OperatingAndFinanceLeaseLiabilityCurrent

rare:OperatingAndFinanceLeaseLiabilityCurrent


Operating
Period End2021-06-302021-03-312020-12-312019-12-31
Value109.388.9767.235
Percentage of OperatingAndFinanceLeaseLiabilityCurrent100.0100.0100.0100.0

rare:OperatingAndFinanceLeaseLiabilityDueAfterYearFive

rare:OperatingAndFinanceLeaseLiabilityDueAfterYearFive


Operating
Period End2020-12-31
Value3456000.0
Percentage of OperatingAndFinanceLeaseLiabilityDueAfterYearFive100.0

rare:OperatingAndFinanceLeaseLiabilityNoncurrent

rare:OperatingAndFinanceLeaseLiabilityNoncurrent


Operating
Period End2021-06-302021-03-312020-12-312019-12-31
Value35363929
Percentage of OperatingAndFinanceLeaseLiabilityNoncurrent100.0100.0100.0100.0

rare:OperatingAndFinanceLeaseLiabilityPaymentsDue

rare:OperatingAndFinanceLeaseLiabilityPaymentsDue


Operating
Period End2020-12-31
Value56
Percentage of OperatingAndFinanceLeaseLiabilityPaymentsDue100.0

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueNextTwelveMonths

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueNextTwelveMonths


Operating
Period End2020-12-31
Value11
Percentage of OperatingAndFinanceLeaseLiabilityPaymentsDueNextTwelveMonths100.0

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearFive

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearFive


Operating
Period End2020-12-31
Value6247000.0
Percentage of OperatingAndFinanceLeaseLiabilityPaymentsDueYearFive100.0

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearFour

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearFour


Operating
Period End2020-12-31
Value10
Percentage of OperatingAndFinanceLeaseLiabilityPaymentsDueYearFour100.0

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearThree

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearThree


Operating
Period End2020-12-31
Value12
Percentage of OperatingAndFinanceLeaseLiabilityPaymentsDueYearThree100.0

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearTwo

rare:OperatingAndFinanceLeaseLiabilityPaymentsDueYearTwo


Operating
Period End2020-12-31
Value12
Percentage of OperatingAndFinanceLeaseLiabilityPaymentsDueYearTwo100.0

rare:OperatingAndFinanceLeaseLiabilityUndiscountedExcessAmount

rare:OperatingAndFinanceLeaseLiabilityUndiscountedExcessAmount


Operating
Period End2020-12-31
Value8510000.0
Percentage of OperatingAndFinanceLeaseLiabilityUndiscountedExcessAmount100.0

rare:PercentageOfGrossAccountsReceivableBalance

rare:PercentageOfGrossAccountsReceivableBalance


Percentage
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value58.054.071.083.00.790.930.870.930.920.890.880.650.810.97
Percentage of PercentageOfGrossAccountsReceivableBalance100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:ReceivableRelatedToLicenseAgreementCurrent us-gaap:CounterpartyName

rare:ReceivableRelatedToLicenseAgreementCurrent

rare:DaiichiSankyoCoLtd


Receivable
Period End2021-06-302021-03-312020-12-312020-06-302020-03-31
Value0.81.31.28.5125
Percentage of ReceivableRelatedToLicenseAgreementCurrent100.0100.0100.0100.0100.0

rare:ReceivableRelatedToLicenseAgreementCurrent us-gaap:CounterpartyName, us-gaap:BalanceSheetLocation

rare:DaiichiSankyoCoLtd, us-gaap:PrepaidExpensesAndOtherCurrentAssets


Receivable
Period End2020-09-30
Value0.9
Percentage of ReceivableRelatedToLicenseAgreementCurrent0.0

rare:ResearchClinicalStudyAndManufacturingExpenses

rare:ResearchClinicalStudyAndManufacturingExpenses


Research
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value222325202129221718181617
Percentage of ResearchClinicalStudyAndManufacturingExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

rare:SalesReserves us-gaap:ProductOrService

rare:SalesReserves

us-gaap:Product


Sales
Period End2020-12-312019-12-312018-12-312017-12-31
Value3913000.01818000.01240000.041000.0
Percentage of SalesReserves100.0100.0100.0100.0

us-gaap:AccountsReceivableNet us-gaap:ProductOrService, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

us-gaap:AccountsReceivableNet

rare:ProfitShareRevenueAndRoyalties, us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value14141623112728211911
Percentage of AccountsReceivableNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccruedLiabilitiesCurrentAndNoncurrent us-gaap:ProductOrService, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

us-gaap:AccruedLiabilitiesCurrentAndNoncurrent

rare:CommercialAndDevelopmentActivityReimbursements, us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312018-12-31
Value2700000.03800000.02400000.01600000.01300000.01000000.0900000.0300000.0
Percentage of AccruedLiabilitiesCurrentAndNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax

us-gaap:AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax


Accumulated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302016-12-31
Value-15000.0-88000.0260000.0905000.01550000.0-1190000.0159000.0337000.0429000.052000.0-304000.0-381000.0-564000.0-631000.0-382000.0-349000.0-494000.0-417000.0
Percentage of AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax

us-gaap:AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax


Accumulated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302016-12-31
Value247000.0144000.0429000.0108000.0-266000.0-355000.0-306000.0-408000.0-174000.0-200000.0-329000.0-29000.0-90000.0-315000.0-5298000.0-7055000.0-3729000.01322000.0
Percentage of AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AvailableForSaleSecurities

us-gaap:AvailableForSaleSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value9411016117274678866374150260470043448254052822337744249748245142747251457030732817519414316152
Percentage of AvailableForSaleSecurities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AvailableForSaleSecurities us-gaap:FairValueByAssetClass

us-gaap:AssetBackedSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value5551118.715151930324022
Percentage of AvailableForSaleSecurities5.85.11.01.21.92.94.16.66.85.2

us-gaap:MoneyMarketFunds


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value206327598135297183293889272
Percentage of AvailableForSaleSecurities22.032.251.018.237.727.639.617.615.316.8

us-gaap:AvailableForSaleSecurities us-gaap:InvestmentType

rare:CertificateOfDepositsAndTimeDeposits


Available
Period End2021-06-302021-03-31
Value1712
Percentage of AvailableForSaleSecurities1.91.2

rare:DebtSecuritiesInGovernmentSponsoredEntities


Available
Period End2021-06-302021-03-31
Value2815
Percentage of AvailableForSaleSecurities3.11.5

rare:USGovernmentTreasuryAndAgencySecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-31
Value54118185262152130150240269991041902001211117747
Percentage of AvailableForSaleSecurities5.811.715.835.219.419.620.347.844.622.846.850.545.424.523.217.19.2

us-gaap:CommercialPaperNotIncludedWithCashAndCashEquivalents


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312016-06-302016-03-312015-12-312015-09-30
Value3412861731029896809613250119.985137.887
Percentage of AvailableForSaleSecurities36.328.214.813.812.514.610.819.322.011.52.82.12.71.4

us-gaap:CorporateBondSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value2372041931932152237734581793912715323220722524026228126521614914913912410044
Percentage of AvailableForSaleSecurities25.220.116.525.927.333.710.46.89.741.417.533.734.846.743.050.156.455.554.846.670.245.584.871.786.962.785.1

us-gaap:RepurchaseAgreements


Available
Period End2020-09-302019-12-312018-12-31
Value3310024
Percentage of AvailableForSaleSecurities4.413.55.5

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value67000.068000.0277000.0912000.01562000.0583000.0172000.0338000.0429000.095000.02000.02000.01000.09000.013000.029000.027000.0143000.0288000.0244000.011000.0157000.019000.014000.06000.017000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax us-gaap:FairValueByAssetClass

us-gaap:AssetBackedSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-312019-09-302019-06-30
Value11000.01000.01000.03000.032000.031000.053000.067000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax16.41.50.40.32.018.015.715.6

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax us-gaap:InvestmentType

rare:DebtSecuritiesInGovernmentSponsoredEntities


Available
Period End2021-06-30
Value4000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax6.0

rare:USGovernmentTreasuryAndAgencySecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-09-302016-12-312016-09-30
Value7000.039000.067000.0167000.0264000.0555000.0124000.0245000.0312000.02000.01000.010000.012000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax10.457.424.218.316.995.272.172.572.7100.011.137.08.4

us-gaap:CommercialPaperNotIncludedWithCashAndCashEquivalents


Available
Period End2020-09-30
Value1000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax0.1

us-gaap:CorporateBondSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value45000.028000.0209000.0741000.01266000.028000.017000.040000.050000.08000.013000.029000.014000.0104000.0103000.0121000.09000.029000.016000.08000.04000.017000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax67.241.275.581.281.04.89.911.811.788.9100.0100.051.972.735.849.681.818.584.257.166.7100.0

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value82000.0156000.017000.07000.012000.01773000.013000.01000.043000.0306000.0383000.0563000.0631000.0380000.0358000.0507000.0472000.0444000.0114000.049000.0152000.0879000.0196000.0228000.0108000.0180000.06000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax us-gaap:FairValueByAssetClass

us-gaap:AssetBackedSecurities


Available
Period End2021-06-302021-03-312020-03-312018-12-31
Value6000.020000.050000.010000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax7.312.82.83.3

us-gaap:AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax us-gaap:InvestmentType

rare:DebtSecuritiesInGovernmentSponsoredEntities


Available
Period End2021-06-302021-03-31
Value14000.011000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax17.17.1

rare:USGovernmentTreasuryAndAgencySecurities


Available
Period End2021-06-302020-06-302018-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-31
Value3000.08000.055000.0290000.0272000.0382000.0316000.0245000.025000.0161000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax3.766.718.076.376.075.366.955.221.918.3

us-gaap:CorporateBondSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302018-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312013-12-31
Value59000.0125000.017000.07000.04000.01723000.013000.01000.0241000.090000.086000.0124000.0149000.0197000.089000.043000.094000.0397000.0145000.0204000.0104000.0172000.06000.0
Percentage of AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax72.080.1100.0100.033.397.2100.0100.078.823.724.024.531.644.478.187.861.845.274.089.596.395.6100.0

us-gaap:AvailableForSaleSecuritiesAmortizedCost

us-gaap:AvailableForSaleSecuritiesAmortizedCost


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value9411016117274578766474150260369943548354152922437844349848345142747251557030832817519514316152
Percentage of AvailableForSaleSecuritiesAmortizedCost100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AvailableForSaleSecuritiesAmortizedCost us-gaap:FairValueByAssetClass

us-gaap:AssetBackedSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value5551118.712151930324022
Percentage of AvailableForSaleSecuritiesAmortizedCost5.85.11.01.21.92.94.16.56.85.2

us-gaap:MoneyMarketFunds


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value206327598135297183293889272
Percentage of AvailableForSaleSecuritiesAmortizedCost22.032.251.018.237.727.639.617.615.316.8

us-gaap:AvailableForSaleSecuritiesAmortizedCost us-gaap:InvestmentType

rare:CertificateOfDepositsAndTimeDeposits


Available
Period End2021-06-302021-03-31
Value1712
Percentage of AvailableForSaleSecuritiesAmortizedCost1.91.2

rare:DebtSecuritiesInGovernmentSponsoredEntities


Available
Period End2021-06-302021-03-31
Value2815
Percentage of AvailableForSaleSecuritiesAmortizedCost3.11.5

rare:USGovernmentTreasuryAndAgencySecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302015-12-31
Value54118185262152129150239269991051912011221127747
Percentage of AvailableForSaleSecuritiesAmortizedCost5.811.715.835.219.419.520.347.744.522.846.950.545.424.523.217.19.2

us-gaap:CommercialPaperNotIncludedWithCashAndCashEquivalents


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312016-06-302016-03-312015-12-312015-09-30
Value3412861731029896809613250119.985137.887
Percentage of AvailableForSaleSecuritiesAmortizedCost36.328.214.813.812.514.610.819.322.011.52.82.12.71.4

us-gaap:CorporateBondSecurities


Available
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value2372041931922142257734581803912715423220722524026228226521614914913912410144
Percentage of AvailableForSaleSecuritiesAmortizedCost25.220.116.525.927.233.910.46.89.741.417.633.734.846.743.050.156.455.554.846.670.245.684.871.786.962.785.1

us-gaap:RepurchaseAgreements


Available
Period End2020-09-302019-12-312018-12-31
Value3310024
Percentage of AvailableForSaleSecuritiesAmortizedCost4.413.55.5

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent


Available
Period End2021-06-302021-03-312020-12-312019-12-31
Value554581488321
Percentage of AvailableForSaleSecuritiesDebtSecuritiesCurrent100.0100.0100.0100.0

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent


Available
Period End2021-06-302021-03-312020-12-312019-12-31
Value12881105.174
Percentage of AvailableForSaleSecuritiesDebtSecuritiesNoncurrent100.0100.0100.0100.0

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-312015-12-31
Value302396726200338300436125133271115851132291036216495
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ContractWithCustomerLiability us-gaap:CounterpartyName

us-gaap:ContractWithCustomerLiability

rare:DaiichiSankyoCoLtd


Contract
Period End2021-06-302021-03-312020-12-312020-09-30
Value3.92566102
Percentage of ContractWithCustomerLiability100.0100.0100.0100.0

us-gaap:ContractualObligationDueInNextTwelveMonths

us-gaap:ContractualObligationDueInNextTwelveMonths


Contractual
Period End2020-12-31
Value30
Percentage of ContractualObligationDueInNextTwelveMonths100.0

us-gaap:ContractualObligationDueInNextTwelveMonths us-gaap:OtherCommitments

rare:LandAndBuildingConstruction


Contractual
Period End2020-12-31
Value26
Percentage of ContractualObligationDueInNextTwelveMonths85.8

rare:ManufacturingAndServices


Contractual
Period End2020-12-31
Value4.33
Percentage of ContractualObligationDueInNextTwelveMonths14.2

us-gaap:ContractualObligationDueInSecondYear

us-gaap:ContractualObligationDueInSecondYear


Contractual
Period End2020-12-31
Value854000.0
Percentage of ContractualObligationDueInSecondYear100.0

us-gaap:ContractualObligationDueInSecondYear us-gaap:OtherCommitments

rare:LandAndBuildingConstruction


Contractual
Period End2020-12-31
Value382000.0
Percentage of ContractualObligationDueInSecondYear44.7

rare:ManufacturingAndServices


Contractual
Period End2020-12-31
Value472000.0
Percentage of ContractualObligationDueInSecondYear55.3

us-gaap:DebtInstrumentFaceAmount us-gaap:CounterpartyName, us-gaap:ShortTermDebtType

us-gaap:DebtInstrumentFaceAmount

rare:DiaCartaLtd, rare:ConvertiblePromissoryNote


Debt
Period End2020-09-30
Value2000000.0
Percentage of DebtInstrumentFaceAmount100.0

us-gaap:DebtInstrumentFaceAmount us-gaap:ShortTermDebtType

rare:ConvertiblePromissoryNote


Debt
Period End2021-06-302021-03-312020-12-31
Value2200000.02100000.02100000.0
Percentage of DebtInstrumentFaceAmount0.00.00.0

us-gaap:DebtInstrumentInterestRateEffectivePercentage us-gaap:CounterpartyName, us-gaap:TypeOfArrangement

us-gaap:DebtInstrumentInterestRateEffectivePercentage

rare:RPIFinanceTrust, rare:RoyaltyPurchaseAgreement


Debt
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value9.89.89.810.30.1030.1020.101
Percentage of DebtInstrumentInterestRateEffectivePercentage100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredIncomeTaxLiabilities


Deferred
Period End2020-12-312019-12-312018-12-31
Value664031
Percentage of DeferredIncomeTaxLiabilities100.0100.0100.0

us-gaap:DeferredIncomeTaxLiabilities us-gaap:FairValueByAssetClass

us-gaap:EquityMethodInvestments


Deferred
Period End2020-12-31
Value23
Percentage of DeferredIncomeTaxLiabilities34.5

us-gaap:DeferredIncomeTaxLiabilities us-gaap:FiniteLivedIntangibleAssetsByMajorClass

us-gaap:InProcessResearchAndDevelopment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value33333131
Percentage of DeferredIncomeTaxLiabilities50.081.3100.00.0

us-gaap:DeferredIncomeTaxLiabilities us-gaap:PropertyPlantAndEquipmentByType

rare:RightOfUseAssets


Deferred
Period End2020-12-312019-12-31
Value107.662
Percentage of DeferredIncomeTaxLiabilities15.518.7

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsGross


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value5944943613042121095125
Percentage of DeferredTaxAssetsGross100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Value2221851831541026132160.30.3
Percentage of DeferredTaxAssetsOperatingLossCarryforwards100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration us-gaap:IncomeTaxAuthority

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration

us-gaap:DomesticCountry


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value7505495584223152258939
Percentage of DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:StateAndLocalJurisdiction


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value6165204764572592559050
Percentage of DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration82.294.685.4108.482.3113.1101.2128.9

us-gaap:DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration us-gaap:IncomeTaxAuthority, us-gaap:TaxCreditCarryforward

us-gaap:DomesticCountry, rare:OrphanDrugCredits


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value179160143124843521
Percentage of DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration24.029.125.729.526.715.624.6

us-gaap:DeferredTaxAssetsOther

us-gaap:DeferredTaxAssetsOther


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value284.1831.1891.2861.950.4320.113
Percentage of DeferredTaxAssetsOther100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxCreditCarryforwards

us-gaap:DeferredTaxAssetsTaxCreditCarryforwards


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value1841581371197833168.692
Percentage of DeferredTaxAssetsTaxCreditCarryforwards100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch us-gaap:IncomeTaxAuthority

us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch

us-gaap:DomesticCountry


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value17117.54.52.51.70.9860.464
Percentage of DeferredTaxAssetsTaxCreditCarryforwardsResearch100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:StateAndLocalJurisdiction


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value342517126.74.31.60.586
Percentage of DeferredTaxAssetsTaxCreditCarryforwardsResearch194.9217.9230.7275.6268.0252.9162.3126.3

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals


Deferred
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-31
Value24197.4185.939102.5410.4760.591
Percentage of DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:EmployeeRelatedLiabilitiesCurrent

us-gaap:EmployeeRelatedLiabilitiesCurrent


Employee
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-312016-12-312016-09-302016-06-302016-03-312015-12-312015-09-302015-06-302015-03-312014-12-312014-09-302014-06-302014-03-312013-12-31
Value41335843352441342820362923162619151017118.985.3399.4237.6684.9723.2174.2052.9742.2081.5572.36
Percentage of EmployeeRelatedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions


Employee
Period End2020-12-31
Value155
Percentage of EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions100.0

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiability


Finance
Period End2020-12-31
Value1161000.0
Percentage of FinanceLeaseLiability100.0

us-gaap:FinanceLeaseLiabilityCurrent

us-gaap:FinanceLeaseLiabilityCurrent


Finance
Period End2020-12-31
Value460000.0
Percentage of FinanceLeaseLiabilityCurrent100.0

us-gaap:FinanceLeaseLiabilityNoncurrent

us-gaap:FinanceLeaseLiabilityNoncurrent


Finance
Period End2020-12-31
Value701000.0
Percentage of FinanceLeaseLiabilityNoncurrent100.0

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDue


Finance
Period End2020-12-31
Value1245000.0
Percentage of FinanceLeaseLiabilityPaymentsDue100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueNextTwelveMonths


Finance
Period End2020-12-31
Value513000.0
Percentage of FinanceLeaseLiabilityPaymentsDueNextTwelveMonths100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueYearThree


Finance
Period End2020-12-31
Value237000.0
Percentage of FinanceLeaseLiabilityPaymentsDueYearThree100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueYearTwo

us-gaap:FinanceLeaseLiabilityPaymentsDueYearTwo


Finance
Period End2020-12-31
Value495000.0
Percentage of FinanceLeaseLiabilityPaymentsDueYearTwo100.0

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount

us-gaap:FinanceLeaseLiabilityUndiscountedExcessAmount


Finance
Period End2020-12-31
Value84000.0
Percentage of FinanceLeaseLiabilityUndiscountedExcessAmount100.0

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent

us-gaap:FinanceLeaseWeightedAverageDiscountRatePercent


Finance
Period End2020-12-31
Value5.58
Percentage of FinanceLeaseWeightedAverageDiscountRatePercent100.0

us-gaap:InterestReceivable us-gaap:CounterpartyName, us-gaap:ShortTermDebtType

us-gaap:InterestReceivable

rare:DiaCartaLtd, rare:ConvertiblePromissoryNote


Interest
Period End2020-09-30
Value100000.0
Percentage of InterestReceivable100.0

us-gaap:InterestReceivable us-gaap:ShortTermDebtType

rare:ConvertiblePromissoryNote


Interest
Period End2021-06-302021-03-312020-12-31
Value400000.0300000.0200000.0
Percentage of InterestReceivable0.00.00.0

us-gaap:InventoryWorkInProcess

us-gaap:InventoryWorkInProcess


Inventory
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value9.4576.7837.184107.6778.2318.19110118.7615.3844.62.881.8080.737
Percentage of InventoryWorkInProcess100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InvestmentOwnedAtFairValue us-gaap:CounterpartyName, us-gaap:ShortTermDebtType

us-gaap:InvestmentOwnedAtFairValue

rare:DiaCartaLtd, rare:ConvertiblePromissoryNote


Investment
Period End2020-07-31
Value2500000.0
Percentage of InvestmentOwnedAtFairValue100.0

rare:MaziTherapeuticsInc, rare:ConvertiblePromissoryNote


Investment
Period End2020-12-31
Value1400000.0
Percentage of InvestmentOwnedAtFairValue0.0

us-gaap:InvestmentOwnedAtFairValue us-gaap:ShortTermDebtType

rare:ConvertiblePromissoryNote


Investment
Period End2020-07-31
Value2500000.0
Percentage of InvestmentOwnedAtFairValue100.0

us-gaap:InvestmentsFairValueDisclosure

us-gaap:InvestmentsFairValueDisclosure


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value104411501327875929698768529628434
Percentage of InvestmentsFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:InvestmentsFairValueDisclosure us-gaap:CounterpartyName, us-gaap:StatementEquityComponents

rare:SolidBiosciencesInc, us-gaap:CommonStock


Investments
Period End2021-06-302021-03-312020-12-31
Value284359
Percentage of InvestmentsFairValueDisclosure2.73.84.5

us-gaap:InvestmentsFairValueDisclosure us-gaap:FairValueByAssetClass

us-gaap:AssetBackedSecurities


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value5551118.715151930324022
Percentage of InvestmentsFairValueDisclosure5.34.50.81.01.62.84.06.26.55.2

us-gaap:MoneyMarketFunds


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value206327598135297183293889248
Percentage of InvestmentsFairValueDisclosure19.828.545.115.532.026.238.116.714.711.3

us-gaap:InvestmentsFairValueDisclosure us-gaap:FairValueByAssetClass, us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:AssetBackedSecurities, us-gaap:FairValueInputsLevel2


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value5551118.715151930324022
Percentage of InvestmentsFairValueDisclosure5.34.50.81.01.62.84.06.26.55.2

us-gaap:MoneyMarketFunds, us-gaap:FairValueInputsLevel1


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value206327598135297183293889248
Percentage of InvestmentsFairValueDisclosure19.828.545.115.532.026.238.116.714.711.3

us-gaap:InvestmentsFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel1


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value32253792147954228341523422748
Percentage of InvestmentsFairValueDisclosure30.946.769.454.858.440.654.144.336.211.3

us-gaap:FairValueInputsLevel2


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value722612406396386412351293399385
Percentage of InvestmentsFairValueDisclosure69.153.330.645.241.659.045.755.463.688.7

us-gaap:InvestmentsFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel, us-gaap:InvestmentType

us-gaap:FairValueInputsLevel1, rare:InvestmentInArcturusCommonStock


Investments
Period End2020-09-30
Value128
Percentage of InvestmentsFairValueDisclosure14.7

us-gaap:FairValueInputsLevel1, rare:InvestmentsInArcturusAndSolidCommonStock


Investments
Period End2021-06-302021-03-312020-12-31
Value103134154
Percentage of InvestmentsFairValueDisclosure9.911.711.7

us-gaap:FairValueInputsLevel1, rare:USGovernmentTreasuryAndAgencySecurities


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-30
Value12751672141046796121112
Percentage of InvestmentsFairValueDisclosure1.26.612.724.511.39.712.522.917.9

us-gaap:FairValueInputsLevel2, rare:CertificateOfDepositsAndTimeDeposits


Investments
Period End2021-06-302021-03-31
Value1712
Percentage of InvestmentsFairValueDisclosure1.71.1

us-gaap:FairValueInputsLevel2, rare:DebtSecuritiesInGovernmentSponsoredEntities


Investments
Period End2021-06-302021-03-31
Value2815
Percentage of InvestmentsFairValueDisclosure2.81.3

us-gaap:FairValueInputsLevel2, rare:USGovernmentTreasuryAndAgencySecurities


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value4242174748625311815799
Percentage of InvestmentsFairValueDisclosure4.03.71.35.55.29.07.022.525.022.8

us-gaap:FairValueInputsLevel2, us-gaap:CommercialPaperNotIncludedWithCashAndCashEquivalents


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value3412861731029896809613250
Percentage of InvestmentsFairValueDisclosure32.724.913.111.810.613.910.418.321.211.5

us-gaap:FairValueInputsLevel2, us-gaap:CorporateBondSecurities


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value237204193193215223773458179
Percentage of InvestmentsFairValueDisclosure22.717.714.622.123.232.010.06.59.341.4

us-gaap:FairValueInputsLevel2, us-gaap:RepurchaseAgreements


Investments
Period End2020-09-302019-12-312018-12-31
Value3310024
Percentage of InvestmentsFairValueDisclosure3.813.05.5

us-gaap:InvestmentsFairValueDisclosure us-gaap:InvestmentType

rare:CertificateOfDepositsAndTimeDeposits


Investments
Period End2021-06-302021-03-31
Value1712
Percentage of InvestmentsFairValueDisclosure1.71.1

rare:DebtSecuritiesInGovernmentSponsoredEntities


Investments
Period End2021-06-302021-03-31
Value2815
Percentage of InvestmentsFairValueDisclosure2.81.3

rare:InvestmentInArcturusCommonStock


Investments
Period End2020-09-30
Value128
Percentage of InvestmentsFairValueDisclosure14.7

rare:InvestmentsInArcturusAndSolidCommonStock


Investments
Period End2021-06-302021-03-312020-12-31
Value103134154
Percentage of InvestmentsFairValueDisclosure9.911.711.7

rare:USGovernmentTreasuryAndAgencySecurities


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value5411818526215213015024026999
Percentage of InvestmentsFairValueDisclosure5.210.314.030.016.518.619.545.442.922.8

us-gaap:CommercialPaperNotIncludedWithCashAndCashEquivalents


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value3412861731029896809613250
Percentage of InvestmentsFairValueDisclosure32.724.913.111.810.613.910.418.321.211.5

us-gaap:CorporateBondSecurities


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-31
Value237204193193215223773458179
Percentage of InvestmentsFairValueDisclosure22.717.714.622.123.232.010.06.59.341.4

us-gaap:RepurchaseAgreements


Investments
Period End2020-09-302019-12-312018-12-31
Value3310024
Percentage of InvestmentsFairValueDisclosure3.813.05.5

us-gaap:InvestmentsFairValueDisclosure us-gaap:StatementEquityComponents, us-gaap:TypeOfArrangement

us-gaap:CommonStock, rare:ArcturusResearchCollaborationAndLicenseAgreement


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302019-12-31
Value74909512814026
Percentage of InvestmentsFairValueDisclosure7.17.97.214.715.13.4

us-gaap:InvestmentsFairValueDisclosure us-gaap:TypeOfArrangement

rare:ArcturusResearchCollaborationAndLicenseAgreement


Investments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-30
Value74909512814032262422
Percentage of InvestmentsFairValueDisclosure7.17.97.214.715.14.73.44.63.6

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths


Lessee
Period End2020-12-31
Value11
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths100.0

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent


Operating
Period End2020-12-31
Value6.7
Percentage of OperatingLeaseWeightedAverageDiscountRatePercent100.0

us-gaap:OtherReceivables us-gaap:BalanceSheetLocation, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType, us-gaap:TypeOfArrangement

us-gaap:OtherReceivables

us-gaap:PrepaidExpensesAndOtherCurrentAssets, us-gaap:LicenseAgreementTerms, rare:KyowaKirinCollaboration


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-30
Value3.85.19.6128.217171513
Percentage of OtherReceivables100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RestrictedCashCurrent

us-gaap:RestrictedCashCurrent


Restricted
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-31
Value10.010100.8470.8470.1610.1610.1610.1610.3510.2710.6520.6520.5420.4610.4611.411
Percentage of RestrictedCashCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RestrictedCashNoncurrent

us-gaap:RestrictedCashNoncurrent


Restricted
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302016-12-31
Value2001000.01921000.01921000.01921000.01921000.02608000.02499000.02499000.02499000.01913000.01822000.01822000.01822000.01931000.02092000.01805000.02076000.0
Percentage of RestrictedCashNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue

us-gaap:PerformanceShares


Share
Period End2020-12-312019-12-312018-12-312017-12-31
Value54.6452.5649.6548.03
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue100.0100.0100.0100.0

us-gaap:RestrictedStockUnitsRSU


Share
Period End2020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-31
Value63.2161.9663.1270.7171.4587.2453.23
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue115.7117.9127.1147.20.00.00.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice


Share
Period End2020-12-31
Value64.35
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue


Share
Period End2023-01-012020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Value184531823377921779192.038
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue


Share
Period End2020-12-31
Value221
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue


Share
Period End2020-12-31
Value430
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice


Share
Period End2020-12-31
Value62.99
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice100.0

us-gaap:UndistributedEarningsOfForeignSubsidiaries

us-gaap:UndistributedEarningsOfForeignSubsidiaries


Undistributed
Period End2020-12-31
Value6300000.0
Percentage of UndistributedEarningsOfForeignSubsidiaries100.0

Line plots across dimensions of each concept


TTM Greenblatt ROC
_
(None,)
T T M  Greenblatt  R O C_
us-gaap:AllocatedShareBasedCompensationExpense
us-gaap:IncomeStatementLocation
(None,)
Allocated Share Based Compensation Expenseus-gaap: Income Statement Location
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ProductOrService
(None,)
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Product Or Service
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ProductOrService, us-gaap:TypeOfArrangement
('us-gaap:Product', None)
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Product Or Service, us-gaap: Type Of Arrangement
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ProductOrService, us-gaap:TypeOfArrangement
(None, 'rare:Crysvita')
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Product Or Service, us-gaap: Type Of Arrangement
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:StatementGeographical
(None,)
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Statement Geographical
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:ProductOrService, us-gaap:StatementGeographical, us-gaap:TypeOfArrangement
(None, 'rare:EuropeanUnionAndSwitzerlandAndTurkey', 'rare:KyowaKirinCollaboration')
Revenue From Contract With Customer Excluding Assessed Taxus-gaap: Product Or Service, us-gaap: Statement Geographical, us-gaap: Type Of Arrangement
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components
us-gaap:PropertyPlantAndEquipmentGross
us-gaap:PropertyPlantAndEquipmentByType
(None,)
Property Plant And Equipment Grossus-gaap: Property Plant And Equipment By Type
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components