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    2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31
Common Stock Value 0.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.01
Weighted Average Number Of Diluted Shares Outstanding 0.090.090.09NA0.0879.7579.45NA78.5077.9776.43NA74.1873.9671.73NA66.2165.4864.6364.2861.2654.9856.01NA
Weighted Average Number Of Shares Outstanding Basic 0.090.090.09NA0.0879.7579.45NA78.5077.9776.43NA74.1873.9671.73NA66.2165.4864.6364.2861.5354.9854.85NA
Weighted Average Number Of Share Outstanding Basic And Diluted NANA0.09NA0.0879.7579.450.0878.5077.9776.430.0774.1873.9671.7368.6566.2165.4864.63NA61.5354.9856.0154.62
Earnings Per Share Basic -2.94-2.65NANA-0.60-1.02NANANANANANANANANANANA-1.67-0.55-0.37-0.78-1.151.53NA
Earnings Per Share Diluted -2.94-2.65NANA-0.60-1.02NANANANANANANANANANANA-1.67-0.55-0.37-0.78-1.151.50NA
Earnings Per Share Basic And Diluted NANA-1.20-1.43-0.60-1.02-2.10-2.40-2.50-1.93-0.23-3.16-1.70-3.74-1.07-2.05-1.15-1.67-0.55-0.39-0.78NANA-1.62

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Revenue From Contract With Customer Excluding Assessed Tax 207.77211.24188.82178.72166.91141.84124.93122.64121.43111.34100.45100.1199.0494.6787.0184.4278.4973.5364.6057.2845.9535.0116.345.42
Revenues 230.27233.49210.83201.46189.41164.09146.93145.14143.92137.36113.67100.1199.0494.6787.0184.4278.4973.5364.6057.2845.9535.0116.345.42
Costs And Expenses 361.62444.62297.71307.27223.86331.66298.80315.85280.99275.72231.70330.33222.63370.04163.40223.78148.59176.9695.3480.4291.8698.3555.5993.82
Research And Development Expense Excluding Acquired In Process Cost 216.71252.33194.25197.30139.12239.62195.15207.24190.44188.52136.14223.14133.95113.2790.55146.2186.58NANANANANANANA
Selling General And Administrative Expense 104.79154.3271.8478.0661.1372.3571.1386.0575.3773.6982.7781.4275.4367.3960.5764.2253.0447.1643.3432.2228.1836.0726.2222.94
Operating Income Loss -131.35-211.13-86.88-105.81-34.46-167.57-151.87-170.72-137.07-138.35-118.03-230.22-123.59-275.37-76.39-139.36-70.10-103.43-30.74-23.15-45.91-63.34-39.24-88.39
Interest Expense 14.7416.0315.8016.0515.9915.8315.6518.7313.8913.7113.628.397.527.437.337.2510.688.147.634.460.800.270.26NA
Interest Expense Debt 14.70NANANA16.00NANANANANANANANANANANANANANANA0.80NANANA
Interest Paid Net 13.4916.0911.6916.2211.9516.0911.6913.965.439.655.384.280.00NANA4.450.80NANA0.990.39NANANA
Gains Losses On Extinguishment Of Debt -125.44NANANANANANANANANANANANANANA0.00-2.30NANANANANANANA
Allocated Share Based Compensation Expense 50.40102.9029.2029.7426.7029.0028.5029.6026.9027.6024.0022.1020.6019.8016.1412.8411.4815.2810.537.376.9210.465.716.87
Income Tax Expense Benefit 1.323.390.880.090.24-0.35-0.140.830.100.020.120.710.230.170.08-0.78-0.670.620.14-1.842.01-0.112.00NA
Profit Loss -257.74-231.48-105.03-121.98-48.14-81.41-167.25-189.32-196.50-150.82-17.49-235.70-126.33-276.40-76.64-140.90-76.39-109.27-35.36-24.00-47.73NANANA
Other Comprehensive Income Loss Net Of Tax -0.72-2.18-0.290.00-0.020.01-0.010.01-0.01-0.620.57-0.03-0.010.060.12-0.110.370.28-0.26-0.370.030.020.07-0.12
Net Income Loss -257.74-231.48-105.03-121.98-48.14-81.41-167.25-189.32-196.50-150.82-17.49-235.70-126.33-276.40-76.64-140.90-76.39-109.27-35.36-24.00-47.73-63.0584.09-88.45
Comprehensive Income Net Of Tax -258.46-233.66-105.31-121.98-48.17-81.40-167.26-189.31-196.51-151.44-16.92-235.73-126.33-276.34-76.53-141.00-76.02-108.98-35.63-24.36-47.71-63.0384.16-88.57

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Assets 3156.152996.853056.153147.972662.222759.072765.232984.722780.662883.042947.391822.821702.471747.751963.891642.081182.911247.161300.281307.96800.28450.14511.53424.10
Liabilities 2725.312270.402199.272219.972192.692273.972229.792222.961888.621840.181802.561004.63707.27648.59615.33609.80543.06548.11523.52518.75103.1272.3782.3987.41
Liabilities And Stockholders Equity 3156.152996.853056.153147.972662.222759.072765.232984.722780.662883.042947.391822.821702.471747.751963.891642.081182.911247.161300.281307.96800.28450.14511.53424.10
Stockholders Equity 430.84726.46856.89928.01469.53485.11535.45761.76892.051042.871144.83818.19995.201099.171348.561032.28639.85699.05776.76789.22697.16377.77429.14336.69

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Assets Current 2625.932469.302530.952604.102185.312265.222271.352485.202322.672459.422547.351468.911362.301427.421671.421426.181012.081139.241219.421228.64735.61390.58457.31373.48
Cash And Cash Equivalents At Carrying Value 1038.62868.571233.882115.871599.111697.281481.841502.651474.641639.961764.21835.08724.83808.59732.19370.83209.70410.38557.23599.69617.63168.35274.72122.42
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents 1057.65887.061243.532125.521608.181706.341490.901511.711483.201648.521772.78843.64733.39817.05737.39370.83209.70410.38557.37599.83617.77168.48NA122.56
Short Term Investments 1033.861059.45779.55NANA30.00256.00435.92341.47421.35406.94289.67324.06294.48612.02803.08583.16538.77491.76479.37NA132.60115.59195.43
Accounts Receivable Net Current 201.51203.85178.19152.99149.79127.52118.20101.34121.83104.03106.8890.8868.0356.9850.5149.0448.6042.9839.8529.4724.7517.7912.285.23
Inventory Net 221.19208.09199.00186.21288.47268.76240.33231.96220.12179.65173.17171.38166.36156.57140.47125.44115.82104.1399.3883.6164.6941.7530.4512.81
Other Assets Current 130.74129.33140.33149.03147.94141.67174.98213.32164.62114.4496.1581.9179.02110.80136.2477.7854.8042.9931.2036.5127.0328.5722.7426.89

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Amortization Of Intangible Assets 0.180.180.180.180.180.180.170.170.170.170.170.200.220.220.220.220.220.220.220.220.780.030.030.03
Property Plant And Equipment Net 181.00183.29187.25191.16199.25203.33203.11190.43171.72153.34137.32129.62119.53117.20106.2897.0276.8457.6253.9343.1638.8739.3938.4137.80
Finite Lived Intangible Assets Net 13.0613.0613.3314.2414.2014.1114.1213.6313.3413.1112.8112.5011.9711.8211.7811.5715.3214.8614.4714.3614.037.797.688.08
Other Assets Noncurrent 293.12284.20278.65292.95190.79203.55211.58203.70201.85182.98186.81173.86169.17151.86133.31107.2978.6635.4412.4721.8110.9911.587.353.97

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Liabilities Current 602.92545.57454.96452.73373.44425.02364.74416.03378.39354.90306.43264.77215.86162.09137.37173.69114.39104.6991.2088.3370.4765.9674.6375.42
Accounts Payable Current 118.4656.2154.0176.7444.1676.6876.65111.0974.5391.6626.5968.0981.9544.0526.5033.8320.4117.3817.388.475.3210.9227.4529.69
Other Accrued Liabilities Current 4.346.573.965.616.044.353.954.474.785.358.217.012.643.403.592.470.441.412.862.482.923.854.043.58
Accrued Liabilities Current 369.00383.70293.91271.70221.01240.14180.64193.55199.06159.09176.30185.53121.66107.33100.12134.0988.6972.4865.6568.9855.7539.1831.1631.02
Other Liabilities Current 26.2116.4217.8015.0519.0318.9618.2022.1415.5514.8412.4611.158.947.416.762.462.002.014.721.391.371.341.381.30
Contract With Customer Liability Current 89.2489.2489.2489.2489.2489.2489.2489.2489.2489.3191.073.303.303.303.983.30NANANA3.32NANANANA

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Long Term Debt 1542.77NANA563.67NANANANANANANANANANANA420.55415.45439.44430.81601.3337.74NANA17.67
Other Liabilities Noncurrent NA11.0011.0011.0020.5720.6420.9819.795.0510.2510.2510.255.255.250.0515.5513.2213.504.965.546.116.415.425.95
Operating Lease Liability Noncurrent 35.2339.3738.6241.5163.4365.2860.6780.3768.2372.4065.2647.7249.7450.21NANANANANANANANANANA

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Stockholders Equity 430.84726.46856.89928.01469.53485.11535.45761.76892.051042.871144.83818.19995.201099.171348.561032.28639.85699.05776.76789.22697.16377.77429.14336.69
Common Stock Value 0.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.01
Additional Paid In Capital Common Stock 4235.034272.194168.964134.773554.313521.723490.663609.883550.863505.163455.693112.133053.423031.053004.112611.292077.862061.042029.772006.601890.171523.081511.421503.13
Retained Earnings Accumulated Deficit -3800.99-3543.25-3311.77-3206.75-3084.77-3036.62-2955.22-2848.13-2658.81-2462.31-2311.49-2294.00-2058.30-1931.97-1655.57-1578.93-1438.03-1361.64-1252.37-1217.01-1193.01-1145.28-1082.23-1166.32
Accumulated Other Comprehensive Income Loss Net Of Tax -3.21-2.48-0.310.02-0.020.00-0.000.00-0.010.010.620.050.070.080.02-0.100.01-0.36-0.64-0.38-0.01-0.04-0.06-0.12

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Net Cash Provided By Used In Operating Activities -64.96-66.81-101.17-29.33-124.33-109.15-180.37-174.53-238.19-107.60627.79-163.79-67.43-79.00-146.23-122.42-113.32-117.25-35.67-31.06-57.90NANANA
Net Cash Provided By Used In Investing Activities 19.12-289.99-785.81-2.5820.27321.06156.67-123.8954.08-34.23-17.6817.08-17.96152.37135.23-237.74-63.40-55.09-14.26-493.69124.95NANANA
Net Cash Provided By Used In Financing Activities 216.430.344.99549.255.903.532.89326.9418.7917.57319.02256.971.736.29377.56521.28-23.9525.357.47506.81382.24NANANA

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Net Cash Provided By Used In Operating Activities -64.96-66.81-101.17-29.33-124.33-109.15-180.37-174.53-238.19-107.60627.79-163.79-67.43-79.00-146.23-122.42-113.32-117.25-35.67-31.06-57.90NANANA
Net Income Loss -257.74-231.48-105.03-121.98-48.14-81.41-167.25-189.32-196.50-150.82-17.49-235.70-126.33-276.40-76.64-140.90-76.39-109.27-35.36-24.00-47.73-63.0584.09-88.45
Profit Loss -257.74-231.48-105.03-121.98-48.14-81.41-167.25-189.32-196.50-150.82-17.49-235.70-126.33-276.40-76.64-140.90-76.39-109.27-35.36-24.00-47.73NANANA
Depreciation Depletion And Amortization 10.709.8910.7210.1410.498.458.937.296.626.476.538.218.287.696.373.533.592.872.252.122.561.771.641.66
Increase Decrease In Accounts Receivable -2.3525.6625.203.2022.279.3216.86-20.4917.80-2.8516.0022.8511.056.471.470.445.623.1410.384.726.965.517.051.24
Increase Decrease In Inventories 26.5410.684.6927.2619.7128.428.3711.8440.476.481.795.029.7916.1015.029.6311.694.7515.7718.9122.9411.3117.639.89
Share Based Compensation 50.42102.8929.2029.7826.6828.9728.5129.5326.9027.6224.0222.0620.6419.7616.1412.8411.4815.2810.537.376.9210.465.716.87
Amortization Of Financing Costs 2.00NANANA1.90NANANANANANANANANANANANANANANANANANANA

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Net Cash Provided By Used In Investing Activities 19.12-289.99-785.81-2.5820.27321.06156.67-123.8954.08-34.23-17.6817.08-17.96152.37135.23-237.74-63.40-55.09-14.26-493.69124.95NANANA
Payments To Acquire Property Plant And Equipment 8.239.085.552.219.245.8921.1528.6125.3019.179.1217.269.4316.6816.2620.2020.098.7012.173.900.772.874.462.91

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Net Cash Provided By Used In Financing Activities 216.430.344.99549.255.903.532.89326.9418.7917.57319.02256.971.736.29377.56521.28-23.9525.357.47506.81382.24NANANA

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Revenues 230.27233.49210.83201.46189.41164.09146.93145.14143.92137.36113.67100.1199.0494.6787.0184.4278.4973.5364.6057.2845.9535.0116.345.42
Revenue From Contract With Customer Excluding Assessed Tax 207.77211.24188.82178.72166.91141.84124.93122.64121.43111.34100.45100.1199.0494.6787.0184.4278.4973.5364.6057.2845.9535.0116.345.42
Roche, Collaborative Arrangement 22.5022.3022.0022.7022.5022.3022.0022.5022.5026.0013.20NANANANANANANANANANANANANA

Plots across concepts


IncomeStatement
Comprehensive Income Net Of Tax
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Income Tax Expense Benefit
Balance Sheet
Operating Lease Right Of Use Asset
Assets
Operating Lease Right Of Use Asset
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Other Assets Current
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CashFlow
Net Income Loss
NetCashProvidedByUsedInOperatingActivities
Net Income Loss
NetCashProvidedByUsedInInvestingActivities
Payments To Acquire Property Plant And Equipment
Shares
Weighted Average Number Of Share Outstanding Basic And Diluted
NonoperatingIncomeExpense
Nonoperating Income Expense
InventoryNet
Inventory Finished Goods Net Of Reserves
AccountsReceivable
Allowance For Doubtful Accounts Receivable Current

Line plots across dimensions of each concept


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