ZYME


Line plots across dimensions of each concept
Line plots across concepts
Tables

Table of contents



us-gaap:CommonStockValue

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareBasicAndDiluted
us-gaap:AwardType
us-gaap:AllocatedShareBasedCompensationExpense

us-gaap:CostsAndExpenses

us-gaap:GeneralAndAdministrativeExpense

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

us-gaap:IncomeTaxExpenseBenefit

us-gaap:InterestIncomeExpenseNonoperatingNet

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic

us-gaap:NetIncomeLossAvailableToCommonStockholdersDiluted

us-gaap:NonoperatingIncomeExpense

us-gaap:OperatingExpenses

us-gaap:OperatingIncomeLoss

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:ResearchAndDevelopmentExpense
us-gaap:IncomeStatementLocation

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
us-gaap:MajorCustomers, us-gaap:ProductOrService

us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax

us-gaap:Revenues
us-gaap:MajorCustomers, us-gaap:ProductOrService

us-gaap:Assets

us-gaap:Liabilities

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents

us-gaap:AssetsCurrent

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:ShortTermInvestments

us-gaap:AccountsReceivableNetCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:PropertyPlantAndEquipmentGross
us-gaap:PropertyPlantAndEquipmentByType

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

us-gaap:AmortizationOfIntangibleAssets

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:LongTermInvestments

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill
us-gaap:IndefiniteLivedIntangibleAssetsByMajorClass

us-gaap:FiniteLivedIntangibleAssetsNet

us-gaap:DeferredTaxAssetsLiabilitiesNet
zyme:DeferredTaxLiabilityMeasurementBasis

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:AccountsPayableAndAccruedLiabilitiesCurrent

us-gaap:LiabilitiesCurrent

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OtherLiabilitiesCurrent

us-gaap:DeferredIncomeTaxLiabilitiesNet

us-gaap:OtherLiabilitiesNoncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:OperatingLeaseLiability

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents

us-gaap:CommonStockValue

us-gaap:AdditionalPaidInCapitalCommonStock

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
us-gaap:StatementEquityComponents

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:IncreaseDecreaseInAccountsReceivable

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetIncomeLoss
us-gaap:StatementEquityComponents

us-gaap:ShareBasedCompensation

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment

us-gaap:NetCashProvidedByUsedInFinancingActivities
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

us-gaap:DeferredTaxLiabilities

us-gaap:DeferredTaxAssetsNet

us-gaap:UnrecognizedTaxBenefits

us-gaap:DeferredTaxAssetsValuationAllowance

us-gaap:CapitalExpendituresIncurredButNotYetPaid

us-gaap:ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure
us-gaap:AwardType
us-gaap:DefinedContributionPlanMaximumAnnualContributionsPerEmployeeAmount

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:FinanceLeasePrincipalPayments

us-gaap:ForeignCurrencyTransactionGainLossBeforeTax

us-gaap:ForeignCurrencyTransactionGainLossUnrealized

us-gaap:IncreaseDecreaseInAccountsPayableAndAccruedLiabilities

us-gaap:IncreaseDecreaseInDeferredIncomeTaxes

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:OperatingLeaseExpense

us-gaap:OperatingLeaseImpairmentLoss

us-gaap:OperatingLeasePayments

us-gaap:OtherNonoperatingExpense

us-gaap:OtherNonoperatingIncome

us-gaap:PaymentsForProceedsFromInvestments

us-gaap:PaymentsForProceedsFromShortTermInvestments

us-gaap:PaymentsToAcquireIntangibleAssets

us-gaap:PaymentsToAcquireLongtermInvestments

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions

us-gaap:ProceedsFromStockOptionsExercised

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
us-gaap:StatementEquityComponents
us-gaap:StatementEquityComponents
us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised
us-gaap:StatementEquityComponents
us-gaap:AwardType
us-gaap:UnrealizedGainLossOnForeignCurrencyDerivativesNetBeforeTax

us-gaap:UnrealizedGainLossOnInvestments

us-gaap:VariableLeasePayment
us-gaap:IncomeStatementLocation
zyme:AllocatedShareBasedCompensationExpenseIncome

zyme:ContingentConsiderationFairValueAdjustments

zyme:DepreciationAndAmortizationOnPropertyAndEquipment
us-gaap:AwardType
zyme:ExerciseOfLiabilityClassifiedOptions
us-gaap:IncomeStatementLocation
zyme:FinanceExpenseIncome

zyme:FixedLeasePayment
us-gaap:IncomeStatementLocation
zyme:GeneralAndAdministrativeExpenseIncome
us-gaap:IncomeStatementLocation
zyme:IncreaseDecreaseInFairValueOfLiabilityClassifiedEquityInstruments
us-gaap:AwardType
zyme:IncreaseDecreaseInFairValueOfLiabilityClassifiedStockOptions

zyme:IncreaseDecreaseInOperatingLeaseLiabilities
us-gaap:Range, us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
zyme:InvestmentInterestPercentage

zyme:LicensingAgreementNoncashConsideration

zyme:OperatingLeaseRightOfUseAssetAmortizationAndImpairment
us-gaap:MajorCustomers, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType
zyme:OptionFeePortionOfFeeReceived
us-gaap:MajorCustomers, us-gaap:DeferredRevenueArrangementType, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType
zyme:OptionFeeTotal

zyme:PaymentsOfDeferredFinancingFees

zyme:ProceedsFromIssuanceOfCommonStockPublicOffering

zyme:ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan
us-gaap:IncomeStatementLocation
zyme:ShareBasedCompensationExpenseAndIncreaseDecreaseInFairValueOfLiabilityClassedEquityInstruments
us-gaap:AwardType
zyme:UnrealizedForeignCurrencyLossGainLiabilityClassifiedStockOptions

us-gaap:AccountsPayableTradeCurrent

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

us-gaap:BusinessCombinationContingentConsiderationLiabilityNoncurrent
us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName
us-gaap:CommercialPaper

us-gaap:ContractWithCustomerLiability
us-gaap:MajorCustomers

us-gaap:DeferredIncomeTaxAssetsNet

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredTaxAssetsDeferredIncome

us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards

us-gaap:DeferredTaxAssetsOther

us-gaap:DeferredTaxAssetsPropertyPlantAndEquipment

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets

us-gaap:DeferredTaxLiabilitiesPropertyPlantAndEquipment

us-gaap:DerivativeFairValueOfDerivativeLiability
us-gaap:AwardType

us-gaap:EmployeeRelatedLiabilitiesCurrent
us-gaap:AwardType
us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiabilityCurrent

us-gaap:FinanceLeaseLiabilityNoncurrent

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:FinancialLiabilitiesFairValueDisclosure
us-gaap:AwardType
us-gaap:AwardType, us-gaap:FairValueByFairValueHierarchyLevel
us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo

us-gaap:FiniteLivedIntangibleAssetsGross

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths

us-gaap:LiabilitiesOtherThanLongtermDebtNoncurrent
us-gaap:Currency
us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent

us-gaap:OperatingLossCarryforwards
us-gaap:TaxPeriod

us-gaap:OtherAccountsPayableAndAccruedLiabilities

us-gaap:PrepaidExpenseNoncurrent
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
us-gaap:AwardType
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
us-gaap:AwardType
us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
us-gaap:AwardType

us-gaap:TaxCreditCarryforwardAmount
us-gaap:TaxCreditCarryforward
us-gaap:TaxPeriod

zyme:AccountsReceivableAfterAllowanceForCreditLossLeaseIncentiveCurrentTotal

zyme:AccruedLegalAndProfessionalFeesCurrent

zyme:AccruedResearchExpensesCurrent
us-gaap:MajorCustomers
zyme:CollaborativeArrangementMaximumExerciseFeesAndMilestonePayments
us-gaap:MajorCustomers
zyme:CollaborativeArrangementMaximumMilestonePaymentsAndTieredRoyalties

zyme:ContingentConsiderationLiabilityFairValueDisclosure

zyme:ContributionsToEmployeeSharePurchasePlan
us-gaap:AwardType

zyme:DeferredFinancingFee

zyme:DeferredTaxAssetsLiabilitiesBeforeValuationAllowance

zyme:DeferredTaxAssetsNonCapitalLossCarryForwards

zyme:DeferredTaxAssetsOperatingLeaseLiability

zyme:DeferredTaxAssetsShareIssueCosts

zyme:DeferredTaxAssetsStockOptions

zyme:DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets

zyme:DeferredTaxLiabilitiesOutsideBasisDifference

zyme:DerivativeLiabilityClassifiedStockOptionsAndESPP

zyme:FiniteLivedIntangibleAssetExpectedAmortization
us-gaap:IndefiniteLivedIntangibleAssetsByMajorClass
zyme:IndefiniteLivedIntangibleAssetsImpairment

zyme:LeaseLiability

zyme:LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount

zyme:LiabilitiesFromInLicensingAgreements

zyme:LiabilityForInLicensingAgreement

zyme:NetMonetaryAssetsDenominatedInForeignCurrency

zyme:ShareBasedCompensationByShareBasedPaymentAwardUnamortizedCompensationExpense

Plots across concepts


IncomeStatement
Operating Income Loss
Expenses
Income Tax Expense Benefit
Balance Sheet
Finite Lived Intangible Assets Net
Assets
Property Plant And Equipment Net
Current Assets
Accounts Receivable Net Current
NonCurrent Assets
Long Term Investments
PropertyPlantAndEquipmentNet
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Liabilities
Operating Lease Liability
Current Liabilities
Other Liabilities Current
Stockholders Equity
Retained Earnings Accumulated Deficit
CashFlow
Net Income Loss
NetCashProvidedByUsedInOperatingActivities
Net Income Loss
NetCashProvidedByUsedInInvestingActivities
Payments To Acquire Property Plant And Equipment
Shares
Weighted Average Number Of Share Outstanding Basic And Diluted
OperatingLeaseLiability
Operating Lease Liability Current
NonoperatingIncomeExpense
Other Nonoperating Income Expense
LesseeOperatingLeaseLiabilityPaymentsDue
Lessee Operating Lease Liability Undiscounted Excess Amount
FiniteLivedIntangibleAssets
Finite Lived Intangible Assets Net

Tables

  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:CommonStockValue ██████▄▄▄▂▂▂▂▁▁730.311729.007724.219715.304708.319707.61450.21444.439441.174320.948320.074319.89319.713223.147222.991NANA
us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding 51.422066NANANA50.788681NANA43.44537932.83797532.020437NA31.95920626.86982925.45915NA25.3492121.038652
us-gaap:WeightedAverageNumberOfSharesOutstandingBasic 51.422066NANANA50.788681NANA43.44537932.83797532.020437NA31.95920626.86982925.45915NA25.33927220.915608
us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted NA51.367663NA50.90363350.78868148.686718NA43.44537932.83797532.020437NANANANANANANA
us-gaap:EarningsPerShareBasic -1.31NANANA-0.77NA-1.8000000000000003-0.7-0.89-0.430.3699999999999999-0.59-0.22-0.831.6900000000000002-0.64-0.55
us-gaap:EarningsPerShareDiluted -1.31NANANA-0.77NA-1.8000000000000003-0.7-0.89-0.430.3699999999999999-0.59-0.22-0.831.6799999999999997-0.65-0.63
us-gaap:EarningsPerShareBasicAndDiluted NA-0.87-0.74-1.43-0.77-0.64-1.66-0.7-0.89-0.43NANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
 us-gaap:AllocatedShareBasedCompensationExpense us-gaap:AwardType us-gaap:RestrictedStockUnitsRSU█▇▅▅▅▁0.7180.6060.4480.4360.4110.091NANA0.00.0NANANANANANANA
 us-gaap:AllocatedShareBasedCompensationExpense us-gaap:AwardType zyme:EmployeesStockPurchasePlan▇█▇▇▄▄▂▃▁▂0.2490.2690.2440.2480.1560.1550.0940.1010.0480.083NANANA0.005NANANA
us-gaap:CostsAndExpenses ▇▅▆█▅▅█▄▄▃▂▂▂▂▂▂▁70.65645.57953.22576.33752.70844.14975.62941.42437.31426.47820.3921.58924.01620.15116.73516.81610.574
us-gaap:GeneralAndAdministrativeExpense ▆▁▄▆▄▃█▄▄▃▂▂▃▂▂▂▁19.9451.29613.96522.80613.4917.62330.2412.17312.7619.0036.2967.4478.6487.0664.7155.2912.285
us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest ▁▃▃▁▃▄▁▄▄▅▆▅▆▄█▅▅-67.956-44.065-37.732-72.605-39.025-30.761-72.746-31.383-28.442-13.4489.618-18.702-4.032-21.26933.002-16.195-10.843
us-gaap:IncomeTaxExpenseBenefit ▃█▆▅▅▇▃▁█▆-0.4340.5250.161-0.043-0.0640.375-0.502-0.9080.6350.193NANANANANANANA
us-gaap:InterestIncomeExpenseNonoperatingNet ▁█0.5880.741NA1.3021.5021.869NA1.9391.2331.262NANANANANANANA
us-gaap:NetIncomeLoss ▁▃▃▁▃▄▁▄▄▅▆▅▅▄█▅▅-67.522-44.59-37.893-72.562-38.961-31.136-72.244-30.475-29.077-13.6419.273-18.751-5.874-21.20432.733-16.245-10.968
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▁█-67.522-44.59NA-72.562-38.961-31.136NA-30.475-29.077-13.6419.273-18.751-5.874-21.204NANANA
us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic -67.522NANANA-38.961NA-72.244-30.475-29.077-13.6419.273-18.751-5.874-21.20432.733-16.245-11.488
us-gaap:NetIncomeLossAvailableToCommonStockholdersDiluted -67.522NANANA-38.961NA-72.244-30.475-29.077-13.6419.273-18.751-5.874-21.20432.603-16.467-13.183
us-gaap:NonoperatingIncomeExpense ▄▄▃▄▄█▄▅▄▄▄▄▁▂▃▃▁0.9290.87-0.1871.0891.3245.1191.0062.1810.991.1051.0830.833-2.016-1.158-0.3340.502-1.611
us-gaap:OperatingExpenses NANA53.22576.33752.70844.14975.62941.42437.31426.478NANANANANANANA
us-gaap:OperatingIncomeLoss ▁▃▃▁▃▃▁▄▄▅▆▅▆▅█▅▅-68.885-44.935-37.545-73.694-40.349-35.88-73.752-33.564-29.432-14.5538.535-19.535-2.016-20.11133.336-16.697-9.232
us-gaap:OtherNonoperatingIncomeExpense ▃▃▁▃▃█▂▃▃▃0.3410.129-1.224-0.213-0.1783.25-0.5940.242-0.243-0.157NANANANANANANA
us-gaap:ResearchAndDevelopmentExpense █▇▆█▆▅▇▄▃▂▂▂▂▂▂▂▁50.71144.28339.2653.53139.21736.52645.38929.25123.78517.47514.08914.14215.36813.08512.87711.5258.289
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax ▁▁▃▁▃▂▁▂▂▃▅▁▄▁█▁▁1.7710.64415.682.64312.3598.2691.8777.867.88211.92528.9252.05422.00.0450.0710.1191.342
us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax NANA15.682.64312.3598.2691.8777.867.88211.92528.9252.05422.00.0450.0710.1191.342
us-gaap:Revenues ▁▁▃▁▃▂▁▂▂▃▅▁▄▁█▁▁1.7710.64415.682.64312.3598.2691.8777.867.88211.92528.9252.05422.00.0450.0710.1191.342
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:Assets ▆▆▇▇██▄▅▅▃▃▂▂▁▁471.954490.059538.376571.719606.853636.578368.205400.037414.547238.279244.363194.44210.995113.538131.955NANA
us-gaap:Liabilities █▆▇▇▆▆▇▅▄▄▄▁▁▁▁150.482112.914128.454139.365115.6114.159122.52490.51280.5368.27263.87324.7724.5319.0115.527NANA
us-gaap:LiabilitiesAndStockholdersEquity ▆▆▇▇██▄▅▅▃▃▂▂▁▁471.954490.059538.376571.719606.853636.578368.205400.037414.547238.279244.363194.44210.995113.538131.955NANA
us-gaap:StockholdersEquity ▅▆▆▇▇█▃▅▅▂▂▂▃▁▁321.472377.145409.922432.354491.253522.419245.681309.525334.017170.007180.49169.67186.46594.528116.428NANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:AssetsCurrent ▆▇▇█▇█▅▅▆▃▃▂▃▁▁392.957432.768455.076487.32471.297504.608311.83345.311366.425190.33204.369153.799172.26374.42192.335NANA
us-gaap:CashAndCashEquivalentsAtCarryingValue ▇█▇▇▆▅▄▇█▁▁▁▂▁▁257.159279.947242.036244.12219.569189.485128.451250.844283.5243.17442.20528.37555.37930.98135.946NANA
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents ▇█▇▇▆▆▄▇█▂▂▁▂▁▂▁▁257.159279.947242.036244.12219.569189.485128.451250.844283.5243.17442.20528.37555.37930.98135.94612.33226.001
us-gaap:ShortTermInvestments ▃▃▅▆▆█▅▂▂▄▄▃▃▁▁102.652131.527184.318227.737217.22298.179170.45384.25972.13137.134157.959121.626110.84839.0551.851NANA
us-gaap:AccountsReceivableNetCurrent ▅▃█▃█▅▂▃▂▁▁▁▁▁▁9.164.57615.2933.69214.8258.6532.1853.3252.7090.7030.3580.2530.3030.0490.238NANA
us-gaap:PrepaidExpenseAndOtherAssetsCurrent █▆▅▄▇▃▄▂▃▃▁▁▂▁▁23.98616.71813.42911.77119.6838.29110.7416.7887.9798.9872.852.5433.8072.4152.208NANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:PropertyPlantAndEquipmentGross NANA22.519NANANA18.332NANANA11.589NANANA10.724NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:ConstructionInProgressNANA0.964NANANA0.915NANANA0.221NANANA0.196NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:FurnitureAndFixturesNANA1.559NANANA1.248NANANA0.747NANANA0.552NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:LeaseholdImprovementsNANA9.054NANANA6.374NANANA3.377NANANA3.022NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType us-gaap:OfficeEquipmentNANA0.971NANANA0.729NANANA0.535NANANA0.484NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType zyme:ComputerHardwareNANA2.691NANANA2.438NANANA1.439NANANA1.575NANA
 us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType zyme:LaboratoryEquipmentNANA7.28NANANA6.628NANANA5.27NANANA4.895NANA
us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment NANA10.334NANANA7.232NANANA5.105NANANA3.546NANA
us-gaap:AmortizationOfIntangibleAssets ████▇▇▇▆▄▄▄▃▁▁▁▁▁1.091.091.0941.0950.9910.980.9570.8540.6490.6530.6560.5360.2820.2760.2770.270.241
us-gaap:PropertyPlantAndEquipmentNet █▆▆▇▇▅▅▅▃▁▁▁▁▂▂13.96812.30512.18512.51712.45211.03211.110.1488.4826.2626.4846.3856.7526.9497.178NANA
us-gaap:LongTermInvestments ▁▁▃▃██▁0.8860.88625.92125.85875.97875.7580.0NANANANANANANANANANA
us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill ▁▁▁▁▁▁▁▁▁██████17.62817.62817.62817.62817.62817.62817.62817.62817.62818.39618.39618.39618.39618.39618.396NANA
us-gaap:FiniteLivedIntangibleAssetsNet ▄▅▆▇█▆▇▇▁▂▂▃▁▁▁3.1634.2135.3036.3977.4925.896.0576.9580.3120.9621.6142.260.2960.5280.748NANA
us-gaap:DeferredTaxAssetsLiabilitiesNet NANA0.545NANANA0.81NANANA0.084NANANA0.067NANA
 us-gaap:DeferredTaxAssetsLiabilitiesNet zyme:DeferredTaxLiabilityMeasurementBasis zyme:DeferredTaxnetNANA0.545NANANA0.81NANANA0.084NANANANANANA
us-gaap:OperatingLeaseRightOfUseAsset █▁▁▁▁▁▁▁▂▂25.4545.4335.4295.2665.6736.325.45.4437.2597.684NANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:AccountsPayableAndAccruedLiabilitiesCurrent █▆▆▇▅▅▅▄▃▂▂▁▂▁▁55.58243.65443.65551.32736.23537.23435.69126.92218.58211.35113.40310.47712.3337.0579.053NANA
us-gaap:LiabilitiesCurrent ▇▆▇█▆▆▇▄▃▂▂▂▂▁▁83.00570.24585.66696.89272.7872.90582.55250.68940.39228.15629.98623.96223.74518.18514.661NANA
us-gaap:OperatingLeaseLiabilityCurrent ▂█▇▃▄▃▁1.6182.9522.711.8721.8951.7491.282NANANANANANANANANANA
us-gaap:OtherLiabilitiesCurrent ▁▁▁▁▁▁▁▁▁█▇▅▃▄▅0.0220.0220.0170.0160.0290.0230.010.0090.0140.5030.450.2770.1470.2050.315NANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:DeferredIncomeTaxLiabilitiesNet █▇▅▅▄▁▃1.8671.5151.1780.9420.7280.00.408NANANANANANANANANANA
us-gaap:OtherLiabilitiesNoncurrent ▇██▇▇▁▁▁2.5772.882.8572.6112.561.0551.0241.039NANA0.946NANANANANANA
us-gaap:OperatingLeaseLiabilityNoncurrent █▁▁▁▁▂▁30.0925.3335.8125.9796.5917.2585.599NANANANANANANANANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:StockholdersEquity ▅▆▆▇▇█▃▅▅▂▂▂▃▁▁321.472377.145409.922432.354491.253522.419245.681309.525334.017170.007180.49169.67186.46594.528116.428NANA
us-gaap:CommonStockValue ██████▄▄▄▂▂▂▂▁▁730.311729.007724.219715.304708.319707.61450.21444.439441.174320.948320.074319.89319.713223.147222.991NANA
us-gaap:AdditionalPaidInCapitalCommonStock ██▇▇▇▆▄▄▄▁▁▁▁▁▁181.193170.648163.623157.077150.399143.31392.83990.2187.49214.63112.34710.9849.2057.968.812NANA
us-gaap:RetainedEarningsAccumulatedDeficit ▁▂▃▃▄▅▅▆▇▇▇▇███-583.373-515.851-471.261-433.368-360.806-321.845-290.709-218.465-187.99-158.913-145.272-154.545-135.794-129.92-108.716NANA
us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue █▁11.0868.53NA7.77.2384.446NA3.313.0382.5331.4051.7841.517-0.83NANANA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:NetCashProvidedByUsedInOperatingActivities ▁▂▁▃▁▂▂▄▄▃█▄▅▃▇▄-50.352-40.803-47.903-16.057-49.956-37.487-36.354-10.88-13.317-21.30250.105-12.8174.46-17.57139.015-12.152NA
us-gaap:NetCashProvidedByUsedInInvestingActivities ▇█▇▇█▁▄▅█▇▅▆▄▆▆▆27.23976.84743.437.58680.345-204.771-88.197-22.77463.37422.005-36.014-13.303-72.26412.535-15.526-1.392NA
us-gaap:NetCashProvidedByUsedInFinancingActivities ▁▁▁▁▁█▁▁▅▁▁▁▃▁▁▁0.6712.1062.6943.2470.205302.8322.1580.999189.9350.569-0.146-0.90592.3510.1310.125-0.162NA
us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect ▃▄▃▄▄▅▁▃█▃▄▃▄▃▄▃-22.78837.911-2.08424.55130.08461.034-122.393-32.676240.3460.96913.83-27.00424.398-4.96523.614-13.669NA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:IncreaseDecreaseInAccountsReceivable ▆▁█▁▆▆▄▅▅▅▄▄▅▄▄▄▅4.584-10.71711.601-11.1346.1736.467-1.1390.6162.0060.3450.104-0.0480.252-0.1890.058-1.2490.961
us-gaap:NetCashProvidedByUsedInOperatingActivities ▁▂▁▃▁▂▂▄▄▃█▄▅▃▇▄-50.352-40.803-47.903-16.057-49.956-37.487-36.354-10.88-13.317-21.30250.105-12.8174.46-17.57139.015-12.152NA
us-gaap:NetIncomeLoss ▁▃▃▁▃▄▁▄▄▅▆▅▅▄█▅▅-67.522-44.59-37.893-72.562-38.961-31.136-72.244-30.475-29.077-13.6419.273-18.751-5.874-21.20432.733-16.245-10.968
 us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents us-gaap:RetainedEarnings▁█-67.522-44.59NA-72.562-38.961-31.136NA-30.475-29.077-13.6419.273-18.751-5.874-21.204NANANA
us-gaap:ShareBasedCompensation ▅▁▄▆▄▂█▄▄▃▃▃▃▃▂▃▂13.133-6.7336.28818.5716.973-2.71628.0317.0999.4884.3781.4983.6234.7773.5430.4581.609-1.614
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:NetCashProvidedByUsedInInvestingActivities ▇█▇▇█▁▄▅█▇▅▆▄▆▆▆27.23976.84743.437.58680.345-204.771-88.197-22.77463.37422.005-36.014-13.303-72.26412.535-15.526-1.392NA
us-gaap:PaymentsToAcquirePropertyPlantAndEquipment ▅▃▄▄▅▂▆█▄▁▂▁▂▁▂▁▂1.7520.6951.0251.11.6550.532.1412.7741.3760.0310.2590.0920.3430.1090.3820.2190.501
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
us-gaap:NetCashProvidedByUsedInFinancingActivities ▁▁▁▁▁█▁▁▅▁▁▁▃▁▁▁0.6712.1062.6943.2470.205302.8322.1580.999189.9350.569-0.146-0.90592.3510.1310.125-0.162NA
  2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value730729724715708707450444441320320319319223222
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets154.7148.8134.5125.1116.7111.2122.3111.1106.4134.7131.0164.5151.5196.5169.0

Weighted Average Number Of Diluted Shares Outstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding

us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding


Weighted
Period End2021-06-302020-06-302019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-31
Value5150433232312625252113
Percentage of WeightedAverageNumberOfDilutedSharesOutstanding100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Weighted Average Number Of Shares Outstanding Basic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic

us-gaap:WeightedAverageNumberOfSharesOutstandingBasic


Weighted
Period End2021-06-302020-06-302019-09-302019-06-302019-03-312018-09-302018-06-302018-03-312017-09-302017-06-302017-03-31
Value5150433232312625252013
Percentage of WeightedAverageNumberOfSharesOutstandingBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Weighted Average Number Of Share Outstanding Basic And Diluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted

us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted


Weighted
Period End2021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value51505048433232
Percentage of WeightedAverageNumberOfShareOutstandingBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Basic

us-gaap:EarningsPerShareBasic

us-gaap:EarningsPerShareBasic


Earnings
Period End2021-06-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-1.31-0.77-1.8-0.7-0.89-0.430.37-0.59-0.22-0.831.69-0.64-0.55-1.21
Percentage of EarningsPerShareBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Diluted

us-gaap:EarningsPerShareDiluted

us-gaap:EarningsPerShareDiluted


Earnings
Period End2021-06-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-1.31-0.77-1.8-0.7-0.89-0.430.37-0.59-0.22-0.831.68-0.65-0.63-1.25
Percentage of EarningsPerShareDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Earnings Per Share Basic And Diluted

us-gaap:EarningsPerShareBasicAndDiluted

us-gaap:EarningsPerShareBasicAndDiluted


Earnings
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value-0.87-0.74-1.43-0.77-0.64-1.66-0.7-0.89-0.43
Percentage of EarningsPerShareBasicAndDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0

Allocated Share Based Compensation Expense

us-gaap:AllocatedShareBasedCompensationExpense us-gaap:AwardType

us-gaap:AllocatedShareBasedCompensationExpense

us-gaap:RestrictedStockUnitsRSU


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-06-302019-03-31
Value718000.0606000.0448000.0436000.0411000.091000.000
Percentage of AllocatedShareBasedCompensationExpense100.0100.0100.0100.0100.0100.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax40.594.12.916.53.31.10.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RestrictedStockUnitsRSU0.00.00.00.00.00.00.00.0

zyme:EmployeesStockPurchasePlan


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-03-31
Value249000.0269000.0244000.0248000.0156000.0155000.094000.0101000.048000.083000.05000.0
Percentage of AllocatedShareBasedCompensationExpense34.744.454.556.938.0170.30.00.00.00.00.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax14.141.81.69.41.31.95.01.30.60.712.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax zyme:EmployeesStockPurchasePlan0.00.00.00.00.00.00.00.00.00.00.0

Costs And Expenses

us-gaap:CostsAndExpenses

us-gaap:CostsAndExpenses


Costs
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value704553765244754137262021242016161016
Percentage of CostsAndExpenses100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax3989.67077.5339.42888.3426.5533.94029.2527.0473.4222.070.51051.1109.250377.533.414131.1787.90.0

General And Administrative Expense

us-gaap:GeneralAndAdministrativeExpense

us-gaap:GeneralAndAdministrativeExpense


General
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value191.2961322137.6233012129.0036.2967.4478.6487.0664.7155.2912.2856.259
Percentage of GeneralAndAdministrativeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1126.2201.289.1862.9109.292.21611.1154.9161.975.521.8362.639.317665.09.44446.2170.30.0

Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-67.956-44.065-37.732-72.605-39.025-30.761-72.746-31.383-28.442-13.4489.618-18.702-4.032-21.26933-16.195-10.843-15.926
Percentage of IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3837.2-6842.4-240.6-2747.1-315.8-372.0-3875.7-399.3-360.8-112.833.3-910.5-18.3-53172.565.9-13609.2-808.00.0

Income Tax Expense Benefit

us-gaap:IncomeTaxExpenseBenefit

us-gaap:IncomeTaxExpenseBenefit


Income
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value-434000.0525000.0161000.0-43000.0-64000.0375000.0-502000.0-908000.0635000.0193000.0
Percentage of IncomeTaxExpenseBenefit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-24.581.51.0-1.6-0.54.5-26.7-11.68.11.6

Interest Income Expense Nonoperating Net

us-gaap:InterestIncomeExpenseNonoperatingNet

us-gaap:InterestIncomeExpenseNonoperatingNet


Interest
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value588000.0741000.01302000.01502000.01869000.01939000.01233000.01262000.0
Percentage of InterestIncomeExpenseNonoperatingNet100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax33.2115.149.312.222.624.715.610.6

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-67.522-44.59-37.893-72.562-38.961-31.136-72.244-30.475-29.077-13.6419.273-18.751-5.874-21.20432-16.245-10.968-15.926
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3812.6-6923.9-241.7-2745.4-315.2-376.5-3848.9-387.7-368.9-114.432.1-912.9-26.7-53010.065.4-13651.3-817.30.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-67.522-44.59-72.562-38.961-31.136-30.475-29.077-13.6419.273-18.751-5.874-21.204
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3812.6-6923.9-2745.4-315.2-376.5-387.7-368.9-114.432.1-912.9-26.7-53010.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.0

Net Income Loss Available To Common Stockholders Basic

us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic

us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic


Net
Period End2021-06-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-67522000.0-38961000.0-72244000.0-30475000.0-29077000.0-13641000.09273000.0-18751000.0-5874000.0-21204000.032733000.0-16245000.0-11488000.0-15926000.0
Percentage of NetIncomeLossAvailableToCommonStockholdersBasic100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3812.6-315.2-3848.9-387.7-368.9-114.432.1-912.9-26.7-53010.065.4-13651.3-856.00.0

Net Income Loss Available To Common Stockholders Diluted

us-gaap:NetIncomeLossAvailableToCommonStockholdersDiluted

us-gaap:NetIncomeLossAvailableToCommonStockholdersDiluted


Net
Period End2021-06-302020-06-302019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-67522000.0-38961000.0-72244000.0-30475000.0-29077000.0-13641000.09273000.0-18751000.0-5874000.0-21204000.032603000.0-16467000.0-13183000.0-16636000.0
Percentage of NetIncomeLossAvailableToCommonStockholdersDiluted100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3812.6-315.2-3848.9-387.7-368.9-114.432.1-912.9-26.7-53010.065.1-13837.8-982.30.0

Nonoperating Income Expense

us-gaap:NonoperatingIncomeExpense

us-gaap:NonoperatingIncomeExpense


Nonoperating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value929000.0870000.0-187000.01089000.01324000.05119000.01006000.02181000.0990000.01105000.01083000.0833000.0-2016000.0-1158000.0-334000.0502000.0-1611000.0479000.0
Percentage of NonoperatingIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax52.5135.1-1.241.210.761.953.627.712.69.33.740.6-9.2-2895.0-0.7421.8-120.00.0

Operating Expenses

us-gaap:OperatingExpenses

us-gaap:OperatingExpenses


Operating
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value5376524475413726
Percentage of OperatingExpenses100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax339.42888.3426.5533.94029.2527.0473.4222.0

Operating Income Loss

us-gaap:OperatingIncomeLoss

us-gaap:OperatingIncomeLoss


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-68.885-44.935-37.545-73.694-40.349-35.88-73.752-33.564-29.432-14.5538.535-19.535-2.016-20.11133-16.697-9.232-16.405
Percentage of OperatingIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3889.6-6977.5-239.4-2788.3-326.5-433.9-3929.2-427.0-373.4-122.029.5-951.1-9.2-50277.566.6-14031.1-687.90.0

Other Nonoperating Income Expense

us-gaap:OtherNonoperatingIncomeExpense

us-gaap:OtherNonoperatingIncomeExpense


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value341000.0129000.0-1224000.0-213000.0-178000.03250000.0-594000.0242000.0-243000.0-157000.0
Percentage of OtherNonoperatingIncomeExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax19.320.0-7.8-8.1-1.439.3-31.63.1-3.1-1.3

Research And Development Expense

us-gaap:ResearchAndDevelopmentExpense

us-gaap:ResearchAndDevelopmentExpense


Research
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value504439533936452923171414151312118.2899.058
Percentage of ResearchAndDevelopmentExpense100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax2863.46876.2250.42025.4317.3441.72418.2372.2301.8146.548.7688.569.932712.525.79684.9617.70.0

us-gaap:ResearchAndDevelopmentExpense us-gaap:IncomeStatementLocation

us-gaap:ResearchAndDevelopmentExpense


Research
Period End2021-06-302021-03-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value6.0351.8233.2390.2227.1172.5783.0551.5470.5451.1871.3111.1920.2560.1770.128
Percentage of ResearchAndDevelopmentExpense11.94.18.30.615.78.812.88.93.98.48.59.12.01.51.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax340.8283.126.22.7379.232.838.813.01.957.86.02980.00.5148.79.5
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:ResearchAndDevelopmentExpense0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Revenue From Contract With Customer Excluding Assessed Tax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax


Revenue
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value1.7710.644152.643128.2691.8777.867.88211282.054220.04500.1191.342
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:MajorCustomers, us-gaap:ProductOrService

zyme:Other, zyme:OtherProduct


Revenue
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value1.7710.6442.6430.3593.2690.361.3820.395
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.02.939.54.617.53.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.02.939.54.617.53.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax zyme:Other zyme:OtherProduct100.0100.0100.0100.0100.0100.0100.0100.0

Revenue From Contract With Customer Including Assessed Tax

us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax

us-gaap:RevenueFromContractWithCustomerIncludingAssessedTax


Revenue
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value152.643128.2691.8777.867.88211282.054220.04500.1191.342
Percentage of RevenueFromContractWithCustomerIncludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Revenues

us-gaap:Revenues

us-gaap:Revenues


Revenues
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value1.7710.644152.643128.2691.8777.867.88211282.054220.04500.1191.342
Percentage of Revenues100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:Revenues us-gaap:MajorCustomers, us-gaap:ProductOrService

zyme:Other, zyme:OtherProduct


Revenuesus-gaap:
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value1.7710.6442.6430.3593.2690.361.3820.395
Percentage of Revenues100.0100.0100.02.939.54.617.53.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax100.0100.0100.02.939.54.617.53.3
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax zyme:Other zyme:OtherProduct100.0100.0100.0100.0100.0100.0100.0100.0

Assets

us-gaap:Assets

us-gaap:Assets


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value471490538571606636368400414238244194210113131
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Liabilities

us-gaap:Liabilities

us-gaap:Liabilities


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1501121281391151141229080686324241915
Percentage of Liabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets31.923.023.924.419.017.933.322.619.428.726.112.711.616.711.8

Liabilities And Stockholders Equity

us-gaap:LiabilitiesAndStockholdersEquity

us-gaap:LiabilitiesAndStockholdersEquity


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value471490538571606636368400414238244194210113131
Percentage of LiabilitiesAndStockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value321377409432491522245309334170180169186941169.00218
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets68.177.076.175.681.082.166.777.480.671.373.987.388.483.388.20.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value1811701631571501439290871412109.2057.968.8126.8564.882
Percentage of StockholdersEquity56.445.239.936.330.627.437.829.126.28.66.86.54.98.47.676.226.8
Percentage of Assets38.434.830.427.524.822.525.222.621.16.15.15.64.47.06.70.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value73072972471570870745044444132032031931922322210683
Percentage of StockholdersEquity227.2193.3176.7165.4144.2135.4183.2143.6132.1188.8177.3188.5171.5236.1191.51184.1458.4
Percentage of Assets154.7148.8134.5125.1116.7111.2122.3111.1106.4134.7131.0164.5151.5196.5169.00.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value-583.373-515.851-471.261-433.368-360.806-321.845-290.709-218.465-187.99-158.913-145.272-154.545-135.794-129.92-108.716-97.79-63.922
Percentage of StockholdersEquity-181.5-136.8-115.0-100.2-73.4-61.6-118.3-70.6-56.3-93.5-80.5-91.1-72.8-137.4-93.4-1086.3-350.5
Percentage of Assets-123.6-105.3-87.5-75.8-59.5-50.6-79.0-54.6-45.3-66.7-59.4-79.5-64.4-114.4-82.40.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Assets Current

us-gaap:AssetsCurrent

us-gaap:AssetsCurrent


Assets
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value3924324554874715043113453661902041531727492
Percentage of AssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets83.388.384.585.277.779.384.786.388.479.983.679.181.665.570.0

Cash And Cash Equivalents At Carrying Value

us-gaap:CashAndCashEquivalentsAtCarryingValue

us-gaap:CashAndCashEquivalentsAtCarryingValue


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-03-312016-12-31
Value2572792422442191891282502834342285530351016
Percentage of CashAndCashEquivalentsAtCarryingValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets54.557.145.042.736.229.834.962.768.418.117.314.626.227.327.20.00.0

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302016-12-312015-12-31
Value25727924224421918912825028343422855303512261611
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets54.557.145.042.736.229.834.962.768.418.117.314.626.227.327.20.00.00.00.0

Short Term Investments

us-gaap:ShortTermInvestments

us-gaap:ShortTermInvestments


Short
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value10213118422721729817084721371571211103951
Percentage of ShortTermInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets21.826.834.239.835.846.846.321.117.457.664.662.652.534.439.3

Accounts Receivable Net Current

us-gaap:AccountsReceivableNetCurrent

us-gaap:AccountsReceivableNetCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value9.164.576153.692148.6532.1853.3252.7090.7030.3580.2530.3030.0490.238
Percentage of AccountsReceivableNetCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets1.90.92.80.62.41.40.60.80.70.30.10.10.10.00.2

Prepaid Expense And Other Assets Current

us-gaap:PrepaidExpenseAndOtherAssetsCurrent

us-gaap:PrepaidExpenseAndOtherAssetsCurrent


Prepaid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value23161311198.291106.7887.9798.9872.852.5433.8072.4152.208
Percentage of PrepaidExpenseAndOtherAssetsCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets5.13.42.52.13.21.32.91.71.93.81.21.31.82.11.7

Property Plant And Equipment Gross

us-gaap:PropertyPlantAndEquipmentGross

us-gaap:PropertyPlantAndEquipmentGross


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value22181110
Percentage of PropertyPlantAndEquipmentGross100.0100.0100.0100.0
Percentage of Assets4.25.04.78.1

us-gaap:PropertyPlantAndEquipmentGross us-gaap:PropertyPlantAndEquipmentByType

us-gaap:ConstructionInProgress


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value0.9640.9150.2210.196
Percentage of PropertyPlantAndEquipmentGross4.35.01.91.8
Percentage of Assets0.20.20.10.1
Percentage of Assets us-gaap:ConstructionInProgress0.00.00.00.0

us-gaap:FurnitureAndFixtures


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value1.5591.2480.7470.552
Percentage of PropertyPlantAndEquipmentGross6.96.86.45.1
Percentage of Assets0.30.30.30.4
Percentage of Assets us-gaap:FurnitureAndFixtures0.00.00.00.0

us-gaap:LeaseholdImprovements


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value9.0546.3743.3773.022
Percentage of PropertyPlantAndEquipmentGross40.234.829.128.2
Percentage of Assets1.71.71.42.3
Percentage of Assets us-gaap:LeaseholdImprovements0.00.00.00.0

us-gaap:OfficeEquipment


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value0.9710.7290.5350.484
Percentage of PropertyPlantAndEquipmentGross4.34.04.64.5
Percentage of Assets0.20.20.20.4
Percentage of Assets us-gaap:OfficeEquipment0.00.00.00.0

zyme:ComputerHardware


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value2.6912.4381.4391.575
Percentage of PropertyPlantAndEquipmentGross11.913.312.414.7
Percentage of Assets0.50.70.61.2
Percentage of Assets zyme:ComputerHardware0.00.00.00.0

zyme:LaboratoryEquipment


Property
Period End2020-12-312019-12-312018-12-312017-12-31
Value7.286.6285.274.895
Percentage of PropertyPlantAndEquipmentGross32.336.245.545.6
Percentage of Assets1.41.82.23.7
Percentage of Assets zyme:LaboratoryEquipment0.00.00.00.0

Accumulated Depreciation Depletion And Amortization Property Plant And Equipment

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment


Accumulated
Period End2020-12-312019-12-312018-12-312017-12-31
Value107.2325.1053.546
Percentage of AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment100.0100.0100.0100.0
Percentage of Assets1.92.02.12.7

Amortization Of Intangible Assets

us-gaap:AmortizationOfIntangibleAssets

us-gaap:AmortizationOfIntangibleAssets


Amortization
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value1090000.01090000.01094000.01095000.0991000.0980000.0957000.0854000.0649000.0653000.0656000.0536000.0282000.0276000.0277000.0270000.0241000.0270000.0
Percentage of AmortizationOfIntangibleAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Property Plant And Equipment Net

us-gaap:PropertyPlantAndEquipmentNet

us-gaap:PropertyPlantAndEquipmentNet


Property
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value13121212121111108.4826.2626.4846.3856.7526.9497.178
Percentage of PropertyPlantAndEquipmentNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets3.02.52.32.22.11.73.02.52.02.62.73.33.26.15.4

Long Term Investments

us-gaap:LongTermInvestments

us-gaap:LongTermInvestments


Long
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value0.8860.886252575750.0
Percentage of LongTermInvestments100.0100.0100.0100.0100.0100.00.0
Percentage of Assets0.20.24.84.512.511.90.0

Indefinite Lived Intangible Assets Excluding Goodwill

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill


Indefinite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value17171717171717171718181818181819
Percentage of IndefiniteLivedIntangibleAssetsExcludingGoodwill100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets3.73.63.33.12.92.84.84.44.37.77.59.58.716.213.90.0

us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill us-gaap:IndefiniteLivedIntangibleAssetsByMajorClass

zyme:IndefiniteLivedIntangibleAssetsInProcessResearchAndDevelopment


Indefinite
Period End2021-06-302021-03-312020-12-312020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value1717171717171718181818181819
Percentage of IndefiniteLivedIntangibleAssetsExcludingGoodwill100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets3.73.63.32.84.84.44.37.77.59.58.716.213.90.0
Percentage of Assets zyme:IndefiniteLivedIntangibleAssetsInProcessResearchAndDevelopment0.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Finite Lived Intangible Assets Net

us-gaap:FiniteLivedIntangibleAssetsNet

us-gaap:FiniteLivedIntangibleAssetsNet


Finite
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value3163000.04213000.05303000.06397000.07492000.05890000.06057000.06958000.0312000.0962000.01614000.02260000.0296000.0528000.0748000.0
Percentage of FiniteLivedIntangibleAssetsNet100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.70.91.01.11.20.91.61.70.10.40.71.20.10.50.6

Deferred Tax Assets Liabilities Net

us-gaap:DeferredTaxAssetsLiabilitiesNet

us-gaap:DeferredTaxAssetsLiabilitiesNet


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value545000.0810000.084000.067000.0
Percentage of DeferredTaxAssetsLiabilitiesNet100.0100.0100.0100.0
Percentage of Assets0.10.20.00.1

us-gaap:DeferredTaxAssetsLiabilitiesNet zyme:DeferredTaxLiabilityMeasurementBasis

zyme:DeferredTaxnet


Deferred
Period End2020-12-312019-12-312018-12-31
Value545000.0810000.084000.0
Percentage of DeferredTaxAssetsLiabilitiesNet100.0100.0100.0
Percentage of Assets0.10.20.0
Percentage of Assets zyme:DeferredTaxnet0.00.00.0

Operating Lease Right Of Use Asset

us-gaap:OperatingLeaseRightOfUseAsset

us-gaap:OperatingLeaseRightOfUseAsset


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312019-01-01
Value255.4335.4295.2665.6736.325.45.4437.2597.6843.222
Percentage of OperatingLeaseRightOfUseAsset100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets5.41.11.00.90.91.01.51.41.83.20.0

Accounts Payable And Accrued Liabilities Current

us-gaap:AccountsPayableAndAccruedLiabilitiesCurrent

us-gaap:AccountsPayableAndAccruedLiabilitiesCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value554343513637352618111310127.0579.053
Percentage of AccountsPayableAndAccruedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets11.88.98.19.06.05.89.76.74.54.85.55.45.86.26.9

Liabilities Current

us-gaap:LiabilitiesCurrent

us-gaap:LiabilitiesCurrent


Liabilities
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value837085967272825040282923231814
Percentage of LiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets17.614.315.916.912.011.522.412.79.711.812.312.311.316.011.1

Operating Lease Liability Current

us-gaap:OperatingLeaseLiabilityCurrent

us-gaap:OperatingLeaseLiabilityCurrent


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value1618000.02952000.02710000.01872000.01895000.01749000.01282000.0
Percentage of OperatingLeaseLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.30.60.50.30.30.30.3

Other Liabilities Current

us-gaap:OtherLiabilitiesCurrent

us-gaap:OtherLiabilitiesCurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value22000.022000.017000.016000.029000.023000.010000.09000.014000.0503000.0450000.0277000.0147000.0205000.0315000.0
Percentage of OtherLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.20.20.10.10.20.2

Deferred Income Tax Liabilities Net

us-gaap:DeferredIncomeTaxLiabilitiesNet

us-gaap:DeferredIncomeTaxLiabilitiesNet


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value1867000.01515000.01178000.0942000.0728000.00408000.0
Percentage of DeferredIncomeTaxLiabilitiesNet100.0100.0100.0100.0100.00.0100.0
Percentage of Assets0.40.30.20.20.10.00.1

Other Liabilities Noncurrent

us-gaap:OtherLiabilitiesNoncurrent

us-gaap:OtherLiabilitiesNoncurrent


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302018-12-31
Value2577000.02880000.02857000.02611000.02560000.01055000.01024000.01039000.0946000.0
Percentage of OtherLiabilitiesNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.50.60.50.50.40.20.30.30.4

Operating Lease Liability Noncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent

us-gaap:OperatingLeaseLiabilityNoncurrent


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value305.3335.8125.9796.5917.2585.599
Percentage of OperatingLeaseLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets6.41.11.11.01.11.11.5

Operating Lease Liability

us-gaap:OperatingLeaseLiability

us-gaap:OperatingLeaseLiability


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312019-01-01
Value318.2858.5227.8518.4869.0076.8816.7557.8298.0653.561
Percentage of OperatingLeaseLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets6.71.71.61.41.41.41.91.71.93.40.0

Lessee Operating Lease Liability Payments Due

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDue


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value388.6518.9238.282
Percentage of LesseeOperatingLeaseLiabilityPaymentsDue100.0100.0100.0100.0
Percentage of Assets8.21.81.71.4

Lessee Operating Lease Liability Undiscounted Excess Amount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

us-gaap:LesseeOperatingLeaseLiabilityUndiscountedExcessAmount


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value6896000.0366000.0401000.0431000.0
Percentage of LesseeOperatingLeaseLiabilityUndiscountedExcessAmount100.0100.0100.0100.0
Percentage of Assets1.50.10.10.1

Stockholders Equity

us-gaap:StockholdersEquity

us-gaap:StockholdersEquity


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value321377409432491522245309334170180169186941169.00218
Percentage of StockholdersEquity100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets68.177.076.175.681.082.166.777.480.671.373.987.388.483.388.20.00.0

us-gaap:StockholdersEquity us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value1811701631571501439290871412109.2057.968.8126.8564.882
Percentage of StockholdersEquity56.445.239.936.330.627.437.829.126.28.66.86.54.98.47.676.226.8
Percentage of Assets38.434.830.427.524.822.525.222.621.16.15.15.64.47.06.70.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:CommonStock


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value73072972471570870745044444132032031931922322210683
Percentage of StockholdersEquity227.2193.3176.7165.4144.2135.4183.2143.6132.1188.8177.3188.5171.5236.1191.51184.1458.4
Percentage of Assets154.7148.8134.5125.1116.7111.2122.3111.1106.4134.7131.0164.5151.5196.5169.00.00.0
Percentage of Assets us-gaap:CommonStock0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:RetainedEarnings


Stockholders
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-312015-12-31
Value-583.373-515.851-471.261-433.368-360.806-321.845-290.709-218.465-187.99-158.913-145.272-154.545-135.794-129.92-108.716-97.79-63.922
Percentage of StockholdersEquity-181.5-136.8-115.0-100.2-73.4-61.6-118.3-70.6-56.3-93.5-80.5-91.1-72.8-137.4-93.4-1086.3-350.5
Percentage of Assets-123.6-105.3-87.5-75.8-59.5-50.6-79.0-54.6-45.3-66.7-59.4-79.5-64.4-114.4-82.40.00.0
Percentage of Assets us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0

Common Stock Value

us-gaap:CommonStockValue

us-gaap:CommonStockValue


Common
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value730729724715708707450444441320320319319223222
Percentage of CommonStockValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets154.7148.8134.5125.1116.7111.2122.3111.1106.4134.7131.0164.5151.5196.5169.0

Additional Paid In Capital Common Stock

us-gaap:AdditionalPaidInCapitalCommonStock

us-gaap:AdditionalPaidInCapitalCommonStock


Additional
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1811701631571501439290871412109.2057.968.812
Percentage of AdditionalPaidInCapitalCommonStock100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets38.434.830.427.524.822.525.222.621.16.15.15.64.47.06.7

Retained Earnings Accumulated Deficit

us-gaap:RetainedEarningsAccumulatedDeficit

us-gaap:RetainedEarningsAccumulatedDeficit


Retained
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value-583370000.0-515850000.0-471260000.0-433370000.0-360810000.0-321840000.0-290710000.0-218460000.0-187990000.0-158910000.0-145270000.0-154540000.0-135790000.0-129920000.0-108720000.0
Percentage of RetainedEarningsAccumulatedDeficit100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets-123.6-105.3-87.5-75.8-59.5-50.6-79.0-54.6-45.3-66.7-59.4-79.5-64.4-114.4-82.4

Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue


Adjustments
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value118.537.77.2384.4463.313.0382.5331.4051.7841.517-0.83
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.0

us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Adjustments
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value118.537.77.2384.4463.313.0382.5331.4051.7841.517-0.83
Percentage of AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of Assets0.00.00.00.00.00.00.00.00.00.00.00.0
Percentage of Assets us-gaap:AdditionalPaidInCapital0.00.00.00.00.00.00.00.00.00.00.00.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-50.352-40.803-47.903-16.057-49.956-37.487-36.354-10.88-13.317-21.30250-12.8174.46-17.57139-12.152
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2843.1-6335.9-305.5-607.5-404.2-453.3-1936.8-138.4-169.0-178.6173.2-624.020.3-43927.577.9-10211.8

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value2776433780-204.771-88.197-22.7746322-36.014-13.303-72.26412-15.526-1.392
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1538.111932.8276.81422.1650.1-2476.4-4698.8-289.7804.0184.5-124.5-647.7-328.531337.5-31.0-1169.7

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value0.6712.1062.6943.2470.2053022.1580.9991890.569-0.146-0.905920.1310.125-0.162
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax37.9327.017.2122.91.73662.3115.012.72409.74.8-0.5-44.1419.8327.50.2-136.1

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect


Cash
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-22.78837-2.084243061-122.393-32.6762400.96913-27.00424-4.96523-13.669
Percentage of CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-1286.75886.8-13.3928.9243.4738.1-6520.7-415.73049.38.147.8-1314.7110.9-12412.547.2-11486.6

Increase Decrease In Accounts Receivable

us-gaap:IncreaseDecreaseInAccountsReceivable

us-gaap:IncreaseDecreaseInAccountsReceivable


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value4.584-10.71711-11.1346.1736.467-1.1390.6162.0060.3450.104-0.0480.252-0.1890.058-1.2490.961-2.179
Percentage of IncreaseDecreaseInAccountsReceivable100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Operating Activities

us-gaap:NetCashProvidedByUsedInOperatingActivities

us-gaap:NetCashProvidedByUsedInOperatingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-50.352-40.803-47.903-16.057-49.956-37.487-36.354-10.88-13.317-21.30250-12.8174.46-17.57139-12.152
Percentage of NetCashProvidedByUsedInOperatingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-2843.1-6335.9-305.5-607.5-404.2-453.3-1936.8-138.4-169.0-178.6173.2-624.020.3-43927.577.9-10211.8

Net Income Loss

us-gaap:NetIncomeLoss

us-gaap:NetIncomeLoss


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-67.522-44.59-37.893-72.562-38.961-31.136-72.244-30.475-29.077-13.6419.273-18.751-5.874-21.20432-16.245-10.968-15.926
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3812.6-6923.9-241.7-2745.4-315.2-376.5-3848.9-387.7-368.9-114.432.1-912.9-26.7-53010.065.4-13651.3-817.30.0

us-gaap:NetIncomeLoss us-gaap:StatementEquityComponents

us-gaap:RetainedEarnings


Net
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-67.522-44.59-72.562-38.961-31.136-30.475-29.077-13.6419.273-18.751-5.874-21.204
Percentage of NetIncomeLoss100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax-3812.6-6923.9-2745.4-315.2-376.5-387.7-368.9-114.432.1-912.9-26.7-53010.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax us-gaap:RetainedEarnings0.00.00.00.00.00.00.00.00.00.00.00.0

Share Based Compensation

us-gaap:ShareBasedCompensation

us-gaap:ShareBasedCompensation


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value13-6.7336.288186.973-2.716287.0999.4884.3781.4983.6234.7773.5430.4581.609-1.6142.976
Percentage of ShareBasedCompensation100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Investing Activities

us-gaap:NetCashProvidedByUsedInInvestingActivities

us-gaap:NetCashProvidedByUsedInInvestingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value2776433780-204.771-88.197-22.7746322-36.014-13.303-72.26412-15.526-1.392
Percentage of NetCashProvidedByUsedInInvestingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax1538.111932.8276.81422.1650.1-2476.4-4698.8-289.7804.0184.5-124.5-647.7-328.531337.5-31.0-1169.7

Payments To Acquire Property Plant And Equipment

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment

us-gaap:PaymentsToAcquirePropertyPlantAndEquipment


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value1752000.0695000.01025000.01100000.01655000.0530000.02141000.02774000.01376000.031000.0259000.092000.0343000.0109000.0382000.0219000.0501000.0913000.0
Percentage of PaymentsToAcquirePropertyPlantAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

Net Cash Provided By Used In Financing Activities

us-gaap:NetCashProvidedByUsedInFinancingActivities

us-gaap:NetCashProvidedByUsedInFinancingActivities


Net
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value0.6712.1062.6943.2470.2053022.1580.9991890.569-0.146-0.905920.1310.125-0.162
Percentage of NetCashProvidedByUsedInFinancingActivities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0
Percentage of RevenueFromContractWithCustomerExcludingAssessedTax37.9327.017.2122.91.73662.3115.012.72409.74.8-0.5-44.1419.8327.50.2-136.1

Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302018-12-312017-12-31
Value25.4125.0322.021.320.4520.216.2115.8814.6614.24
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-12-31
Value26.3625.9522.8522.0521.5620.5615.8514.0513.5211.679.7
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice103.7103.7103.9103.5105.4101.897.888.50.079.668.1

Deferred Tax Liabilities

us-gaap:DeferredTaxLiabilities

us-gaap:DeferredTaxLiabilities


Deferred
Period End2020-12-312019-12-312018-12-31
Value1178000.0408000.0114000.0
Percentage of DeferredTaxLiabilities100.0100.0100.0

Deferred Tax Assets Net

us-gaap:DeferredTaxAssetsNet

us-gaap:DeferredTaxAssetsNet


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value1.7231.2183728
Percentage of DeferredTaxAssetsNet100.0100.0100.0100.0

Unrecognized Tax Benefits

us-gaap:UnrecognizedTaxBenefits

us-gaap:UnrecognizedTaxBenefits


Unrecognized
Period End2020-12-312019-12-312018-12-31
Value3063000.03063000.0672000.0
Percentage of UnrecognizedTaxBenefits100.0100.0100.0

Deferred Tax Assets Valuation Allowance

us-gaap:DeferredTaxAssetsValuationAllowance

us-gaap:DeferredTaxAssetsValuationAllowance


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value115663728
Percentage of DeferredTaxAssetsValuationAllowance100.0100.0100.0100.0

us-gaap:CapitalExpendituresIncurredButNotYetPaid

us-gaap:CapitalExpendituresIncurredButNotYetPaid


Capital
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value898000.0383000.0-438000.0-138000.0136000.0570000.0-449000.0-536000.01350000.0242000.0319000.022000.0-63000.0104000.0-286000.0352000.0-367000.0424000.0
Percentage of CapitalExpendituresIncurredButNotYetPaid100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure

us-gaap:ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure


Concentration
Period End2021-03-31
Value4.576
Percentage of ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure100.0

us-gaap:DefinedContributionPlanMaximumAnnualContributionsPerEmployeeAmount us-gaap:AwardType

us-gaap:DefinedContributionPlanMaximumAnnualContributionsPerEmployeeAmount

zyme:EmployeesStockPurchasePlan


Defined
Period End2021-06-302021-03-312020-12-31
Value025000.00
Percentage of DefinedContributionPlanMaximumAnnualContributionsPerEmployeeAmount0.0100.00.0

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents


Effect
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-346000.0-239000.0-275000.0-225000.0-510000.0460000.00-21000.0354000.0-303000.0-115000.021000.0-149000.0-60000.0037000.0
Percentage of EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents100.0100.0100.0100.0100.0100.00.0100.0100.0100.0100.0100.0100.0100.00.0100.0

us-gaap:FinanceLeasePrincipalPayments

us-gaap:FinanceLeasePrincipalPayments


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value4000.04000.04000.030000.03000.04000.03000.02000.03000.08000.03000.03000.02000.03000.0
Percentage of FinanceLeasePrincipalPayments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ForeignCurrencyTransactionGainLossBeforeTax

us-gaap:ForeignCurrencyTransactionGainLossBeforeTax


Foreign
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value435000.0-63000.0-1227000.0-148000.0-165000.03223000.0-367000.0117000.0-178000.0-139000.0277000.0-79000.0-60000.0-66000.0-135000.0107000.0-64000.0189000.0
Percentage of ForeignCurrencyTransactionGainLossBeforeTax100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ForeignCurrencyTransactionGainLossUnrealized

us-gaap:ForeignCurrencyTransactionGainLossUnrealized


Foreign
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-204000.0-717000.0-1799000.0-614000.0-1171000.04037000.0-352000.0123000.0176000.0-451000.0302000.0-92000.0-82000.0-80000.073000.066000.0-39000.0154000.0
Percentage of ForeignCurrencyTransactionGainLossUnrealized100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInAccountsPayableAndAccruedLiabilities

us-gaap:IncreaseDecreaseInAccountsPayableAndAccruedLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value10-0.163-7.49916-2.8311.0659.1239.6535.164-2.3682.666-1.0684.231-2.1453.743-0.456-1.39-2.255
Percentage of IncreaseDecreaseInAccountsPayableAndAccruedLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:IncreaseDecreaseInDeferredIncomeTaxes

us-gaap:IncreaseDecreaseInDeferredIncomeTaxes


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value651000.0-246000.0-258000.0183000.0160000.0-351000.0555000.0120000.051000.00-157000.0119000.0
Percentage of IncreaseDecreaseInDeferredIncomeTaxes100.0100.0100.0100.0100.0100.0100.0100.0100.00.0100.0100.0

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value7.3432.6571.981-7.74611-2.6023.113-1.538-1.228.3251.064-1.1981.3050.173-1.195-1.3281.4741.076
Percentage of IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingLeaseExpense

us-gaap:OperatingLeaseExpense


Operating
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312019-09-30
Value1375000.01003000.0890000.0893000.0884000.0698000.0
Percentage of OperatingLeaseExpense100.0100.0100.0100.0100.0100.0

us-gaap:OperatingLeaseImpairmentLoss

us-gaap:OperatingLeaseImpairmentLoss


Operating
Period End2020-12-312020-09-302020-06-30
Value00187000.0
Percentage of OperatingLeaseImpairmentLoss0.00.0100.0

us-gaap:OperatingLeasePayments

us-gaap:OperatingLeasePayments


Operating
Period End2021-06-302021-03-312020-12-31
Value780000.0764000.0980000.0
Percentage of OperatingLeasePayments100.0100.0100.0

us-gaap:OtherNonoperatingExpense

us-gaap:OtherNonoperatingExpense


Other
Period End2021-06-302020-12-312020-09-302020-06-302019-06-30
Value94000.0-3000.065000.013000.065000.0
Percentage of OtherNonoperatingExpense100.0100.0100.0100.0100.0

us-gaap:OtherNonoperatingIncome

us-gaap:OtherNonoperatingIncome


Other
Period End2021-06-302021-03-312020-06-302020-03-312019-09-30
Value-94000.0192000.0027000.0125000.0
Percentage of OtherNonoperatingIncome100.0100.00.0100.0100.0

us-gaap:PaymentsForProceedsFromInvestments

us-gaap:PaymentsForProceedsFromInvestments


Payments
Period End2021-06-302021-03-312020-06-302020-03-312019-06-302019-03-31
Value-29.031-77.542-82.0203-64.75-22.036
Percentage of PaymentsForProceedsFromInvestments100.0100.0100.0100.0100.0100.0

us-gaap:PaymentsForProceedsFromShortTermInvestments

us-gaap:PaymentsForProceedsFromShortTermInvestments


Payments
Period End2020-12-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-44.4258612-64.75-22.036351071-12.7150.122
Percentage of PaymentsForProceedsFromShortTermInvestments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PaymentsToAcquireIntangibleAssets

us-gaap:PaymentsToAcquireIntangibleAssets


Payments
Period End2020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value01536000.00419000.056000.07500000.00010000.02500000.051000.056000.024000.01051000.028000.03000.0
Percentage of PaymentsToAcquireIntangibleAssets0.0100.00.0100.0100.0100.00.00.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PaymentsToAcquireLongtermInvestments

us-gaap:PaymentsToAcquireLongtermInvestments


Payments
Period End2020-12-31
Value0.0
Percentage of PaymentsToAcquireLongtermInvestments0.0

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions

us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value763000.01321000.02718000.02598000.0348000.01447000.02811000.01440000.0885000.0362000.0101000.021000.0526000.034000.0440000.020000.0
Percentage of ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ProceedsFromStockOptionsExercised

us-gaap:ProceedsFromStockOptionsExercised


Proceeds
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-03-31
Value763000.01321000.02598000.0348000.01447000.01439000.0767000.0480000.0133000.027000.0680000.043000.0450000.0
Percentage of ProceedsFromStockOptionsExercised100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability

us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability


Right
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value200.4850.590.0-0.1651.9820.344-1.330.08.012
Percentage of RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability100.0100.0100.00.0100.0100.0100.0100.00.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue

us-gaap:RestrictedStockUnitsRSU


Share
Period End2021-06-302021-03-31
Value-0.537.18
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue

us-gaap:RestrictedStockUnitsRSU


Share
Period End2021-06-302021-03-31
Value0.2135.2
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-06-302020-03-31
Value0.011.01-0.020.66
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate100.0100.0100.0100.0

zyme:CanadianDollarUnderTheNewStockOptionPlan


Share
Period End2020-09-302019-09-30
Value0.60361.4454
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate0.00.0

zyme:LiabilityClassifiedStockOptions


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value0.140.450.160.2669-0.0020.00510.00210.0005-0.00110.01530.0039000.01550000.0155
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate1400.044.60.00.010.00.80.00.00.00.00.00.00.00.00.00.00.00.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value0.010.96-0.010.6827-0.00070.008-0.0013-0.0007-0.00060.02490.00050.0001
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate100.095.00.00.03.51.20.00.00.00.00.00.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-06-302020-03-31
Value-0.681.60.375.2
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate100.0100.0100.0100.0

zyme:CanadianDollarUnderTheNewStockOptionPlan


Share
Period End2020-09-302019-09-30
Value75.44572.962
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate0.00.0

zyme:LiabilityClassifiedStockOptions


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-302017-03-31
Value-10.986.8-8.284.5430.0550.8020.03290.011-0.05080.76780.0577000.665-0.0004000.665
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate1816.7106.40.00.018.31.10.00.00.00.00.00.00.00.00.00.00.00.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-30
Value-0.781.60.3575.8370.010.7530.00240.00020.00190.7270.00780.001
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate116.7100.00.00.03.31.00.00.00.00.00.00.0

us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value-0.8718.73-1.46-0.540.1915.631.93
Percentage of ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-30
Value-4.8919.251.811.17-0.1911.80.383.76
Percentage of ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice562.1102.8-124.0-216.7-100.075.519.70.0

us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value-7.3252.465.930.612.2225.130.97
Percentage of ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-30
Value-0.1533.3502.172.2613.58-0.612.44
Percentage of ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice2.063.60.0355.7101.854.0-62.90.0

us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value-1.2444.510.64-0.250.1348.71.58
Percentage of ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice100.0100.0100.0100.0100.0100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-30
Value-1.336.750.99-0.2-0.0436.362.820.94
Percentage of ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice104.882.6154.780.0-30.874.7178.50.0

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan


Stock
Period End2021-03-312020-09-302020-03-312019-09-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value1321000.01003000.0615000.0438000.0325000.00152000.00100000.0
Percentage of StockIssuedDuringPeriodValueEmployeeStockPurchasePlan100.0100.0100.0100.0100.00.0100.00.0100.0

us-gaap:StockIssuedDuringPeriodValueEmployeeStockPurchasePlan us-gaap:StatementEquityComponents

us-gaap:CommonStock


Stock
Period End2021-03-312020-09-302020-03-312019-09-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value1321000.01003000.0615000.0438000.0325000.00152000.00100000.0
Percentage of StockIssuedDuringPeriodValueEmployeeStockPurchasePlan100.0100.0100.0100.0100.00.0100.00.0100.0

us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures us-gaap:StatementEquityComponents

us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures

us-gaap:AdditionalPaidInCapital


Stock
Period End2021-06-302021-03-31
Value-86000.0-843000.0
Percentage of StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures100.0100.0

us-gaap:CommonStock


Stock
Period End2021-06-302021-03-31
Value86000.0843000.0
Percentage of StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures-100.0-100.0

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised


Stock
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value0.7631.9624.960.5572.0132.2352.0440.4190.1420.0470.6020.034
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised us-gaap:StatementEquityComponents

us-gaap:AdditionalPaidInCapital


Stock
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value-0.455-0.662-1.022-0.152-0.754-0.592-0.241-0.13-0.042-0.005-0.272-0.022
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised-59.6-33.7-20.6-27.3-37.5-26.5-11.8-31.0-29.6-10.6-45.2-64.7

us-gaap:CommonStock


Stock
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value1.2182.6245.9820.7092.7672.8272.2850.5490.1840.0520.8740.056
Percentage of StockIssuedDuringPeriodValueStockOptionsExercised159.6133.7120.6127.3137.5126.5111.8131.0129.6110.6145.2164.7

us-gaap:UnrealizedGainLossOnForeignCurrencyDerivativesNetBeforeTax us-gaap:AwardType

us-gaap:UnrealizedGainLossOnForeignCurrencyDerivativesNetBeforeTax

zyme:LiabilityClassifiedStockOptions


Unrealized
Period End2021-03-31
Value-505000.0
Percentage of UnrealizedGainLossOnForeignCurrencyDerivativesNetBeforeTax100.0

us-gaap:UnrealizedGainLossOnInvestments

us-gaap:UnrealizedGainLossOnInvestments


Unrealized
Period End2021-06-302021-03-31
Value0167000.0
Percentage of UnrealizedGainLossOnInvestments0.0100.0

us-gaap:VariableLeasePayment

us-gaap:VariableLeasePayment


Variable
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312019-09-30
Value85000.0117000.087000.0141000.0149000.041000.0
Percentage of VariableLeasePayment100.0100.0100.0100.0100.0100.0

zyme:AllocatedShareBasedCompensationExpenseIncome us-gaap:IncomeStatementLocation

zyme:AllocatedShareBasedCompensationExpenseIncome

us-gaap:GeneralAndAdministrativeExpense


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value5.2964.1923.7554.3934.0462.2281.9461.7211.5791.490.9351.0931.0740.5910.0670.8890.231
Percentage of AllocatedShareBasedCompensationExpenseIncome100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ResearchAndDevelopmentExpense


Allocated
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value5.794.3363.2483.5553.3462.0161.6151.691.5071.1270.4790.6910.6210.4160.1830.6840.345
Percentage of AllocatedShareBasedCompensationExpenseIncome109.3103.486.580.982.790.583.098.295.475.651.263.257.870.4273.176.9149.4

zyme:ContingentConsiderationFairValueAdjustments

zyme:ContingentConsiderationFairValueAdjustments


Contingent
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value031000.0239000.0068000.00-14000.00263000.022000.0184000.0
Percentage of ContingentConsiderationFairValueAdjustments0.0100.0100.00.0100.00.0100.00.0100.0100.0100.0

zyme:DepreciationAndAmortizationOnPropertyAndEquipment

zyme:DepreciationAndAmortizationOnPropertyAndEquipment


Depreciation
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-302018-06-302018-03-31
Value987000.0958000.0897000.0764000.0775000.0572000.0505000.0496000.0480000.0477000.0443000.0
Percentage of DepreciationAndAmortizationOnPropertyAndEquipment100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:ExerciseOfLiabilityClassifiedOptions us-gaap:AwardType

zyme:ExerciseOfLiabilityClassifiedOptions

zyme:LiabilityClassifiedStockOptions


Exercise
Period End2021-03-312020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302018-12-312018-09-302018-06-30
Value641000.05181000.02364000.0209000.01795000.0796000.01156000.040000.026000.076000.0
Percentage of ExerciseOfLiabilityClassifiedOptions100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:FinanceExpenseIncome us-gaap:IncomeStatementLocation

zyme:FinanceExpenseIncome

zyme:FinanceExpenseIncome


Finance
Period End2021-06-302021-03-312020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-66000.0-66000.0-2000.0-34000.080000.018000.053000.015000.0-2000.039000.029000.084000.0-6000.0-34000.0
Percentage of FinanceExpenseIncome100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:FixedLeasePayment

zyme:FixedLeasePayment


Fixed
Period End2021-06-302021-03-312020-12-312020-09-302019-12-312019-09-302019-06-302019-03-31
Value1290000.0886000.0802000.0753000.0780000.01190000.0136000.0533000.0
Percentage of FixedLeasePayment100.0100.0100.0100.0100.0100.0100.0100.0

zyme:GeneralAndAdministrativeExpenseIncome us-gaap:IncomeStatementLocation

zyme:GeneralAndAdministrativeExpenseIncome

us-gaap:GeneralAndAdministrativeExpense


General
Period End2021-06-302021-03-312020-06-302020-03-312018-12-312018-09-302018-06-302017-12-312017-09-302017-06-30
Value6841000.0-8759000.03736000.0-3151000.0955000.02397000.03437000.0208000.01467000.0-1469000.0
Percentage of GeneralAndAdministrativeExpenseIncome100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:IncreaseDecreaseInFairValueOfLiabilityClassifiedEquityInstruments us-gaap:IncomeStatementLocation

zyme:IncreaseDecreaseInFairValueOfLiabilityClassifiedEquityInstruments

us-gaap:GeneralAndAdministrativeExpense


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value1545000.0-12951000.0979000.0-8195000.0310000.05379000.0-18562000.0-2781000.0-4800000.0-1326000.0-20000.0-1304000.0-2363000.0-1676000.0-141000.0-578000.01700000.0
Percentage of IncreaseDecreaseInFairValueOfLiabilityClassifiedEquityInstruments100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ResearchAndDevelopmentExpense


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-302017-06-30
Value245000.0-2513000.0485000.0-2379000.0107000.01794000.0-5502000.0-888000.0-1548000.0-420000.0-66000.0-496000.0-690000.0-776000.0-73000.0507000.0217000.0
Percentage of IncreaseDecreaseInFairValueOfLiabilityClassifiedEquityInstruments15.919.449.529.034.533.429.631.932.231.7330.038.029.246.351.8-87.712.8

zyme:FinanceExpenseIncome


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312017-09-30
Value-66000.0-66000.054000.0-49000.02000.034000.0-80000.0-18000.00-15000.02000.0-39000.0-29000.0-84000.06000.035000.0
Percentage of IncreaseDecreaseInFairValueOfLiabilityClassifiedEquityInstruments-4.30.55.50.60.60.60.40.6-0.01.1-10.03.01.25.0-4.3-6.1

zyme:IncreaseDecreaseInFairValueOfLiabilityClassifiedStockOptions us-gaap:AwardType

zyme:IncreaseDecreaseInFairValueOfLiabilityClassifiedStockOptions

zyme:LiabilityClassifiedStockOptions


Increase
Period End2021-03-312020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302018-12-312018-09-302018-06-30
Value-15.531-1.51810-0.419243.6876.4020.0481.7913.245
Percentage of IncreaseDecreaseInFairValueOfLiabilityClassifiedStockOptions100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:IncreaseDecreaseInOperatingLeaseLiabilities

zyme:IncreaseDecreaseInOperatingLeaseLiabilities


Increase
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value3149000.0-824000.0-37000.0-933000.0-422000.0252000.0-754000.0487000.0-248000.0-280000.0
Percentage of IncreaseDecreaseInOperatingLeaseLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:InvestmentInterestPercentage us-gaap:Range, us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

zyme:InvestmentInterestPercentage

srt:Maximum, zyme:LongTermGuaranteedInvestmentCertificates


Investment
Period End2020-09-302020-06-302020-03-31
Value1.59-0.0060.016
Percentage of InvestmentInterestPercentage100.0100.0100.0

srt:Maximum, zyme:ShortTermGuaranteedInvestmentCertificates


Investment
Period End2020-09-302020-06-302020-03-31
Value1.68-0.0010.021
Percentage of InvestmentInterestPercentage105.716.7131.2

srt:Minimum, zyme:LongTermGuaranteedInvestmentCertificates


Investment
Period End2020-09-302020-06-302020-03-31
Value0.89100.009
Percentage of InvestmentInterestPercentage56.0-0.056.2

srt:Minimum, zyme:ShortTermGuaranteedInvestmentCertificates


Investment
Period End2020-09-302020-06-302020-03-31
Value0.492-0.0010.009
Percentage of InvestmentInterestPercentage30.916.756.2

zyme:LicensingAgreementNoncashConsideration

zyme:LicensingAgreementNoncashConsideration


Licensing
Period End2020-12-312020-09-302020-06-302020-03-312019-06-302019-03-31
Value000218000.000
Percentage of LicensingAgreementNoncashConsideration0.00.00.0100.00.00.0

zyme:OperatingLeaseRightOfUseAssetAmortizationAndImpairment

zyme:OperatingLeaseRightOfUseAssetAmortizationAndImpairment


Operating
Period End2021-06-302021-03-312020-09-302020-06-302020-03-312019-09-302019-06-302019-03-31
Value683000.0572000.0681000.0510000.01062000.0259000.0431000.0329000.0
Percentage of OperatingLeaseRightOfUseAssetAmortizationAndImpairment100.0100.0100.0100.0100.0100.0100.0100.0

zyme:OptionFeePortionOfFeeReceived us-gaap:MajorCustomers, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType

zyme:OptionFeePortionOfFeeReceived

zyme:IconicTherapeuticsInc, zyme:ResearchAndLicenseAgreement


Option
Period End2020-12-31
Value4000000.0
Percentage of OptionFeePortionOfFeeReceived100.0

zyme:OptionFeeTotal us-gaap:MajorCustomers, us-gaap:DeferredRevenueArrangementType, us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersByType

zyme:OptionFeeTotal

zyme:IconicTherapeuticsInc, us-gaap:UpFrontPaymentArrangement, zyme:ResearchAndLicenseAgreement


Option
Period End2020-12-31
Value20
Percentage of OptionFeeTotal100.0

zyme:PaymentsOfDeferredFinancingFees

zyme:PaymentsOfDeferredFinancingFees


Payments
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-06-302019-03-31
Value88000.040000.020000.013000.0140000.0-60000.0-18000.018000.0
Percentage of PaymentsOfDeferredFinancingFees100.0100.0100.0100.0100.0100.0100.0100.0

zyme:ProceedsFromIssuanceOfCommonStockPublicOffering

zyme:ProceedsFromIssuanceOfCommonStockPublicOffering


Proceeds
Period End2020-09-302020-06-302020-03-312019-09-302019-06-302019-03-312018-09-30
Value0.00.0300-0.8041890.0-1.075
Percentage of ProceedsFromIssuanceOfCommonStockPublicOffering0.00.0100.0100.0100.00.0100.0

zyme:ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan

zyme:ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan


Proceeds
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-31
Value0829000.00692000.00419000.00365000.00233000.0-19000.0152000.00100000.0
Percentage of ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan0.0100.00.0100.00.0100.00.0100.00.0100.0100.0100.00.0100.0

zyme:ShareBasedCompensationExpenseAndIncreaseDecreaseInFairValueOfLiabilityClassedEquityInstruments us-gaap:IncomeStatementLocation

zyme:ShareBasedCompensationExpenseAndIncreaseDecreaseInFairValueOfLiabilityClassedEquityInstruments

us-gaap:GeneralAndAdministrativeExpense


Share
Period End2020-09-302020-06-302019-09-302019-06-30
Value123.7364.5026.379
Percentage of ShareBasedCompensationExpenseAndIncreaseDecreaseInFairValueOfLiabilityClassedEquityInstruments100.0100.0100.0100.0

us-gaap:ResearchAndDevelopmentExpense


Share
Period End2020-09-302020-06-302019-09-302019-06-30
Value5.9343.2392.5783.055
Percentage of ShareBasedCompensationExpenseAndIncreaseDecreaseInFairValueOfLiabilityClassedEquityInstruments47.186.757.347.9

zyme:FinanceExpenseIncome


Share
Period End2020-09-302020-06-302019-09-302019-06-30
Value0.049-0.0020.0180.0
Percentage of ShareBasedCompensationExpenseAndIncreaseDecreaseInFairValueOfLiabilityClassedEquityInstruments0.4-0.10.40.0

zyme:UnrealizedForeignCurrencyLossGainLiabilityClassifiedStockOptions us-gaap:AwardType

zyme:UnrealizedForeignCurrencyLossGainLiabilityClassifiedStockOptions

zyme:LiabilityClassifiedStockOptions


Unrealized
Period End2020-12-312020-09-302020-06-302019-12-312019-09-302019-06-302018-12-312018-09-302018-06-30
Value2306000.0797000.01350000.0-940000.0-172000.0234000.0-613000.0178000.0-137000.0
Percentage of UnrealizedForeignCurrencyLossGainLiabilityClassifiedStockOptions100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AccountsPayableTradeCurrent

us-gaap:AccountsPayableTradeCurrent


Accounts
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value4.6614.8766.2443.1294.735125.3498.044.0821.442.5991.2215.6160.9591.664
Percentage of AccountsPayableTradeCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent


Available
Period End2020-12-31
Value718000.0
Percentage of AvailableForSaleSecuritiesDebtSecuritiesNoncurrent100.0

us-gaap:AvailableForSaleSecuritiesDebtSecuritiesNoncurrent us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

zyme:LongTermGuaranteedInvestmentCertificates


Available
Period End2020-09-302020-06-302020-03-312019-12-31
Value718000.0718000.0718000.00
Percentage of AvailableForSaleSecuritiesDebtSecuritiesNoncurrent0.00.00.00.0

us-gaap:BusinessCombinationContingentConsiderationLiabilityNoncurrent

us-gaap:BusinessCombinationContingentConsiderationLiabilityNoncurrent


Business
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302017-12-31
Value1316000.01316000.01285000.01046000.01046000.0978000.0978000.0992000.0992000.0729000.0707000.0523000.0470000.0470000.0
Percentage of BusinessCombinationContingentConsiderationLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:CommercialPaper us-gaap:ScheduleOfEquityMethodInvestmentEquityMethodInvesteeName

us-gaap:CommercialPaper

zyme:LongTermGuaranteedInvestmentCertificates


Commercial
Period End2020-12-312020-09-302020-06-302020-03-312019-12-31
Value252575750.0
Percentage of CommercialPaper100.0100.0100.0100.00.0

us-gaap:ContractWithCustomerLiability

us-gaap:ContractWithCustomerLiability


Contract
Period End2020-12-312020-09-302020-06-302019-12-312018-12-312018-09-302018-06-302018-01-01
Value3232320.0329410.0364710.00.00.0
Percentage of ContractWithCustomerLiability100.0100.0100.0100.0100.00.00.00.0

us-gaap:ContractWithCustomerLiability us-gaap:MajorCustomers

zyme:BeiGene


Contract
Period End2021-06-302021-03-312020-12-312020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value323232323232323236
Percentage of ContractWithCustomerLiability0.00.0100.00.0100000.00.00.00.0100000.0

us-gaap:DeferredIncomeTaxAssetsNet

us-gaap:DeferredIncomeTaxAssetsNet


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value2815000.01813000.01723000.01745000.01347000.0459000.01218000.0
Percentage of DeferredIncomeTaxAssetsNet100.0100.0100.0100.0100.0100.0100.0

us-gaap:DeferredIncomeTaxLiabilities

us-gaap:DeferredIncomeTaxLiabilities


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value8415000.06767000.05153000.04689000.0
Percentage of DeferredIncomeTaxLiabilities100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsDeferredIncome

us-gaap:DeferredTaxAssetsDeferredIncome


Deferred
Period End2020-12-312019-12-312018-12-31
Value8894000.08894000.09848000.0
Percentage of DeferredTaxAssetsDeferredIncome100.0100.0100.0

us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets

us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets


Deferred
Period End2020-12-312019-12-31
Value1352000.0191000.0
Percentage of DeferredTaxAssetsGoodwillAndIntangibleAssets100.0100.0

us-gaap:DeferredTaxAssetsGross

us-gaap:DeferredTaxAssetsGross


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value124744232
Percentage of DeferredTaxAssetsGross100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment

us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value27212017
Percentage of DeferredTaxAssetsInProcessResearchAndDevelopment100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards

us-gaap:DeferredTaxAssetsOperatingLossCarryforwards


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value2651222443
Percentage of DeferredTaxAssetsOperatingLossCarryforwards100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsOther

us-gaap:DeferredTaxAssetsOther


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value280000.0348000.0314000.034000.0
Percentage of DeferredTaxAssetsOther100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsPropertyPlantAndEquipment

us-gaap:DeferredTaxAssetsPropertyPlantAndEquipment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value1423000.01731000.01167000.0956000.0
Percentage of DeferredTaxAssetsPropertyPlantAndEquipment100.0100.0100.0100.0

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies

us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value366000.0264000.0191000.0127000.0
Percentage of DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies100.0100.0100.0100.0

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets

us-gaap:DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value4760000.04760000.04967000.04619000.0
Percentage of DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets100.0100.0100.0100.0

us-gaap:DeferredTaxLiabilitiesPropertyPlantAndEquipment

us-gaap:DeferredTaxLiabilitiesPropertyPlantAndEquipment


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value1296000.0583000.054000.070000.0
Percentage of DeferredTaxLiabilitiesPropertyPlantAndEquipment100.0100.0100.0100.0

us-gaap:DerivativeFairValueOfDerivativeLiability

us-gaap:DerivativeFairValueOfDerivativeLiability


Derivative
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value252339433433452220141213118.2333.945
Percentage of DerivativeFairValueOfDerivativeLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:DerivativeFairValueOfDerivativeLiability us-gaap:AwardType

zyme:LiabilityClassifiedStockOptions


Derivative
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-312016-12-31
Value2339433433452220141213118.2233.9452.458
Percentage of DerivativeFairValueOfDerivativeLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.099.9100.00.0

us-gaap:EmployeeRelatedLiabilitiesCurrent

us-gaap:EmployeeRelatedLiabilitiesCurrent


Employee
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value8397000.05536000.09439000.06584000.04863000.02899000.05009000.03430000.02309000.01602000.02926000.02055000.01508000.0954000.01981000.0
Percentage of EmployeeRelatedLiabilitiesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized us-gaap:AwardType

us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized

us-gaap:RestrictedStockUnitsRSU


Employee
Period End2021-06-302021-03-312020-12-31
Value4191000.04977000.01510000.0
Percentage of EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized100.0100.0100.0

us-gaap:FinanceLeaseLiability

us-gaap:FinanceLeaseLiability


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value133000.0136000.0139000.0131000.093000.0100000.056000.056000.059000.049000.057000.0
Percentage of FinanceLeaseLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityCurrent

us-gaap:FinanceLeaseLiabilityCurrent


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value22000.022000.017000.016000.029000.023000.010000.09000.014000.013000.0136000.0148000.0130000.0138000.0147000.0
Percentage of FinanceLeaseLiabilityCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityNoncurrent

us-gaap:FinanceLeaseLiabilityNoncurrent


Finance
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value111000.0114000.0122000.0115000.064000.077000.046000.047000.045000.036000.0197000.0239000.0267000.0304000.0344000.0
Percentage of FinanceLeaseLiabilityNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDue

us-gaap:FinanceLeaseLiabilityPaymentsDue


Finance
Period End2020-12-312020-09-30
Value141000.0133000.0
Percentage of FinanceLeaseLiabilityPaymentsDue100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths

us-gaap:FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths


Finance
Period End2020-12-312020-09-30
Value17000.016000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFive


Finance
Period End2020-12-312020-09-30
Value28000.054000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearFive100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearFour


Finance
Period End2020-12-312020-09-30
Value50000.020000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearFour100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearThree


Finance
Period End2020-12-312020-09-30
Value23000.022000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearThree100.0100.0

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:FinanceLeaseLiabilityPaymentsDueInRollingYearTwo


Finance
Period End2020-12-312020-09-30
Value23000.021000.0
Percentage of FinanceLeaseLiabilityPaymentsDueInRollingYearTwo100.0100.0

us-gaap:FinancialLiabilitiesFairValueDisclosure

us-gaap:FinancialLiabilitiesFairValueDisclosure


Financial
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1.316244044353446232115131311115.763
Percentage of FinancialLiabilitiesFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FinancialLiabilitiesFairValueDisclosure us-gaap:AwardType

zyme:LiabilityClassifiedStockOptions


Financial
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value2339433433452220141213118.2333.945
Percentage of FinancialLiabilitiesFairValueDisclosure94.796.897.797.197.297.995.895.395.394.796.296.072.368.5

zyme:LiabilityForContingentConsideration


Financial
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1.3161.3161.2851.0461.0460.9780.9780.9920.9920.7290.7070.5230.470.470.47
Percentage of FinancialLiabilitiesFairValueDisclosure100.05.33.22.32.92.82.14.24.74.75.33.84.04.18.2

us-gaap:FinancialLiabilitiesFairValueDisclosure us-gaap:AwardType, us-gaap:FairValueByFairValueHierarchyLevel

zyme:LiabilityClassifiedStockOptions, us-gaap:FairValueInputsLevel3


Financial
Period End2021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value2339433433452220141213118.2333.945
Percentage of FinancialLiabilitiesFairValueDisclosure94.796.897.797.197.297.995.895.395.394.796.296.072.368.5

zyme:LiabilityForContingentConsideration, us-gaap:FairValueInputsLevel3


Financial
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1.3161.3161.2851.0461.0460.9780.9780.9920.9920.7290.7070.5230.470.470.47
Percentage of FinancialLiabilitiesFairValueDisclosure100.05.33.22.32.92.82.14.24.74.75.33.84.04.18.2

us-gaap:FinancialLiabilitiesFairValueDisclosure us-gaap:FairValueByFairValueHierarchyLevel

us-gaap:FairValueInputsLevel3


Financial
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1.316244044353446232115131311115.763
Percentage of FinancialLiabilitiesFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization

us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization


Finite
Period End2020-12-312019-12-312018-12-312017-12-31
Value116.9283.8152.064
Percentage of FiniteLivedIntangibleAssetsAccumulatedAmortization100.0100.0100.0100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths


Finite
Period End2020-12-31
Value2786000.0
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive


Finite
Period End2020-12-31
Value427000.0
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearFive100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour


Finite
Period End2020-12-31
Value427000.0
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearFour100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree


Finite
Period End2020-12-31
Value438000.0
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearThree100.0

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo

us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo


Finite
Period End2020-12-31
Value583000.0
Percentage of FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo100.0

us-gaap:FiniteLivedIntangibleAssetsGross

us-gaap:FiniteLivedIntangibleAssetsGross


Finite
Period End2020-12-312019-12-312018-12-312017-12-31
Value16125.4292.812
Percentage of FiniteLivedIntangibleAssetsGross100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive


Lessee
Period End2021-06-30
Value16
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value4745000.0794000.01186000.01577000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value4722000.01556000.01546000.01535000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value4673000.01614000.01641000.01493000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value4703000.01622000.01712000.01633000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo100.0100.0100.0100.0

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths

us-gaap:LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value2806000.03065000.02838000.02044000.0
Percentage of LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths100.0100.0100.0100.0

us-gaap:LiabilitiesOtherThanLongtermDebtNoncurrent

us-gaap:LiabilitiesOtherThanLongtermDebtNoncurrent


Liabilities
Period End2020-12-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value2857000.01024000.01039000.01037000.0765000.0946000.0808000.0785000.0825000.0866000.0
Percentage of LiabilitiesOtherThanLongtermDebtNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent us-gaap:Currency

us-gaap:OperatingLeaseWeightedAverageDiscountRatePercent

currency:CAD


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value4.74.64.64.60.0460.0460.0460.0460.0460.046
Percentage of OperatingLeaseWeightedAverageDiscountRatePercent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

currency:USD


Operating
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-31
Value2.22.72.72.70.0270.0270.0290.0290.0290.029
Percentage of OperatingLeaseWeightedAverageDiscountRatePercent46.858.758.758.758.758.763.063.063.063.0

us-gaap:OperatingLossCarryforwards

us-gaap:OperatingLossCarryforwards


Operating
Period End2020-12-312019-12-312018-12-31
Value26512224
Percentage of OperatingLossCarryforwards100.0100.0100.0

us-gaap:OperatingLossCarryforwards us-gaap:TaxPeriod

zyme:TaxYear2039


Operating
Period End2020-12-312019-12-31
Value8183
Percentage of OperatingLossCarryforwards30.768.0

zyme:TaxYear2040


Operating
Period End2020-12-31
Value144
Percentage of OperatingLossCarryforwards54.6

zyme:TaxYearTwoThousandThirtySix


Operating
Period End2020-12-312019-12-312018-12-31
Value242414
Percentage of OperatingLossCarryforwards9.320.157.1

us-gaap:OtherAccountsPayableAndAccruedLiabilities

us-gaap:OtherAccountsPayableAndAccruedLiabilities


Other
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value2435000.01243000.01151000.02025000.02218000.0898000.0840000.0827000.01175000.0394000.0689000.0196000.043000.0100000.0227000.0
Percentage of OtherAccountsPayableAndAccruedLiabilities100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:PrepaidExpenseNoncurrent

us-gaap:PrepaidExpenseNoncurrent


Prepaid
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value2152000.02149000.02290000.02217000.02240000.02277000.02306000.02278000.02292000.02181000.01135000.01162000.01150000.01182000.01215000.0
Percentage of PrepaidExpenseNoncurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue

us-gaap:RestrictedStockUnitsRSU


Share
Period End2021-06-302021-03-312020-12-31
Value36.2836.4935.19
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue100.0100.0100.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-312019-12-31
Value15.8914.49
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-312019-12-31
Value14.211.21
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice89.477.4

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302018-12-312017-12-31
Value494387101737710142141.455
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302018-12-312017-12-31
Value4739929155548428214.8760.015
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue95.692.0105.990.575.169.983.367.90.033.81.0

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-312019-12-31
Value8699
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-312019-12-31
Value9081
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue104.481.4

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-312019-12-31
Value21.7216.15
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-312019-12-31
Value22.6115.79
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice104.197.8

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue us-gaap:AwardType

us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

zyme:CADDollarsUnderTheNewStockOptionPlan


Share
Period End2020-12-31
Value67
Percentage of ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue100.0

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1 us-gaap:AwardType

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1

zyme:CADDollarsUnderTheNewStockOptionPlan


Sharebased
Period End2020-12-312019-12-31
Value7072
Percentage of SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1100.0100.0

zyme:USDollarsUnderTheNewStockOptionPlan


Sharebased
Period End2020-12-312019-12-31
Value4924
Percentage of SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue170.233.6

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue


Sharebased
Period End2020-12-312019-12-312018-12-312017-12-31
Value24.4416.0310.259.64
Percentage of SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue100.0100.0100.0100.0

us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue us-gaap:AwardType

us-gaap:EmployeeStockOption


Sharebased
Period End2020-12-312019-12-312018-12-312017-12-31
Value18.7511.217.313.58
Percentage of SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue76.769.971.337.1

us-gaap:TaxCreditCarryforwardAmount

us-gaap:TaxCreditCarryforwardAmount


Tax
Period End2020-12-312019-12-312018-12-312017-12-31
Value118.19.0097.0
Percentage of TaxCreditCarryforwardAmount100.0100.0100.0100.0

us-gaap:TaxCreditCarryforwardAmount us-gaap:TaxCreditCarryforward

us-gaap:Research


Tax
Period End2020-12-312019-12-312018-12-31
Value695850
Percentage of TaxCreditCarryforwardAmount594.0718.5558.3

us-gaap:TaxCreditCarryforwardAmount us-gaap:TaxPeriod

zyme:TaxYear2039


Tax
Period End2020-12-312019-12-31
Value1.8181.749
Percentage of TaxCreditCarryforwardAmount15.521.6

zyme:TaxYear2040


Tax
Period End2020-12-31
Value2.162
Percentage of TaxCreditCarryforwardAmount18.5

zyme:TaxYearTwoThousandThirty


Tax
Period End2020-12-312018-12-31
Value1.3650.01
Percentage of TaxCreditCarryforwardAmount11.70.1

zyme:TaxYearTwoThousandThirtyEight


Tax
Period End2020-12-312019-12-312018-12-31
Value1.4851.4851.513
Percentage of TaxCreditCarryforwardAmount12.718.316.8

zyme:TaxYearTwoThousandThirtyFour


Tax
Period End2020-12-312019-12-312018-12-31
Value0.2290.230.381
Percentage of TaxCreditCarryforwardAmount2.02.84.2

zyme:TaxYearTwoThousandThirtySeven


Tax
Period End2020-12-312019-12-312018-12-31
Value1.5861.5871.777
Percentage of TaxCreditCarryforwardAmount13.619.619.7

zyme:TaxYearTwoThousandThirtySix


Tax
Period End2020-12-312019-12-312018-12-31
Value0.8620.8780.862
Percentage of TaxCreditCarryforwardAmount7.410.89.6

zyme:TaxYearTwoThousandTwentyNine


Tax
Period End2020-12-312019-12-31
Value1.1691.078
Percentage of TaxCreditCarryforwardAmount10.013.3

zyme:AccountsReceivableAfterAllowanceForCreditLossLeaseIncentiveCurrentTotal

zyme:AccountsReceivableAfterAllowanceForCreditLossLeaseIncentiveCurrentTotal


Accounts
Period End2021-06-30
Value3598000.0
Percentage of AccountsReceivableAfterAllowanceForCreditLossLeaseIncentiveCurrentTotal100.0

zyme:AccruedLegalAndProfessionalFeesCurrent

zyme:AccruedLegalAndProfessionalFeesCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value1132000.0472000.0859000.0624000.0598000.01327000.0231000.01036000.0652000.0651000.0556000.0644000.0438000.0670000.0308000.0
Percentage of AccruedLegalAndProfessionalFeesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:AccruedResearchExpensesCurrent

zyme:AccruedResearchExpensesCurrent


Accrued
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312018-09-302018-06-302018-03-312017-12-31
Value3831253823192413107.2646.6336.3614.7284.3744.708
Percentage of AccruedResearchExpensesCurrent100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:CollaborativeArrangementMaximumExerciseFeesAndMilestonePayments us-gaap:MajorCustomers

zyme:CollaborativeArrangementMaximumExerciseFeesAndMilestonePayments

zyme:MerckSharpAndDohmeResearchLtd


Collaborative
Period End2020-07-31
Value419
Percentage of CollaborativeArrangementMaximumExerciseFeesAndMilestonePayments100.0

zyme:CollaborativeArrangementMaximumMilestonePaymentsAndTieredRoyalties us-gaap:MajorCustomers

zyme:CollaborativeArrangementMaximumMilestonePaymentsAndTieredRoyalties

zyme:MerckSharpAndDohmeResearchLtd


Collaborative
Period End2020-07-31
Value502
Percentage of CollaborativeArrangementMaximumMilestonePaymentsAndTieredRoyalties100.0

zyme:ContingentConsiderationLiabilityFairValueDisclosure

zyme:ContingentConsiderationLiabilityFairValueDisclosure


Contingent
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-31
Value1316000.01316000.01285000.01046000.01046000.0978000.0978000.0992000.0992000.0729000.0707000.0470000.0
Percentage of ContingentConsiderationLiabilityFairValueDisclosure100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:ContributionsToEmployeeSharePurchasePlan

zyme:ContributionsToEmployeeSharePurchasePlan


Contributions
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-31
Value1296000.0685000.0926000.0463000.0701000.0357000.0435000.0
Percentage of ContributionsToEmployeeSharePurchasePlan100.0100.0100.0100.0100.0100.0100.0

zyme:ContributionsToEmployeeSharePurchasePlan us-gaap:AwardType

zyme:EmployeesStockPurchasePlan


Contributions
Period End2020-12-312019-12-312018-12-31
Value926000.0435000.0359000.0
Percentage of ContributionsToEmployeeSharePurchasePlan100.0100.00.0

zyme:DeferredFinancingFee

zyme:DeferredFinancingFee


Deferred
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-03-312018-12-31
Value915000.0848000.0805000.0755000.0730000.0590000.0650000.0366000.0265000.0
Percentage of DeferredFinancingFee100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:DeferredTaxAssetsLiabilitiesBeforeValuationAllowance

zyme:DeferredTaxAssetsLiabilitiesBeforeValuationAllowance


Deferred
Period End2020-12-312019-12-31
Value11567
Percentage of DeferredTaxAssetsLiabilitiesBeforeValuationAllowance100.0100.0

zyme:DeferredTaxAssetsNonCapitalLossCarryForwards

zyme:DeferredTaxAssetsNonCapitalLossCarryForwards


Deferred
Period End2020-12-312019-12-31
Value7133
Percentage of DeferredTaxAssetsNonCapitalLossCarryForwards100.0100.0

zyme:DeferredTaxAssetsOperatingLeaseLiability

zyme:DeferredTaxAssetsOperatingLeaseLiability


Deferred
Period End2020-12-312019-12-31
Value1837000.01540000.0
Percentage of DeferredTaxAssetsOperatingLeaseLiability100.0100.0

zyme:DeferredTaxAssetsShareIssueCosts

zyme:DeferredTaxAssetsShareIssueCosts


Deferred
Period End2020-12-312019-12-312018-12-31
Value8365000.05473000.03428000.0
Percentage of DeferredTaxAssetsShareIssueCosts100.0100.0100.0

zyme:DeferredTaxAssetsStockOptions

zyme:DeferredTaxAssetsStockOptions


Deferred
Period End2020-12-312019-12-312018-12-312017-12-31
Value2038000.01242000.0220000.0102000.0
Percentage of DeferredTaxAssetsStockOptions100.0100.0100.0100.0

zyme:DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets

zyme:DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets


Deferred
Period End2020-12-312019-12-31
Value1181000.01016000.0
Percentage of DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets100.0100.0

zyme:DeferredTaxLiabilitiesOutsideBasisDifference

zyme:DeferredTaxLiabilitiesOutsideBasisDifference


Deferred
Period End2020-12-312019-12-31
Value1178000.0434000.0
Percentage of DeferredTaxLiabilitiesOutsideBasisDifference100.0100.0

zyme:DerivativeLiabilityClassifiedStockOptionsAndESPP

zyme:DerivativeLiabilityClassifiedStockOptionsAndESPP


Derivative
Period End2020-12-312019-12-312018-12-31
Value2.171367.658
Percentage of DerivativeLiabilityClassifiedStockOptionsAndESPP100.0100.0100.0

zyme:FiniteLivedIntangibleAssetExpectedAmortization

zyme:FiniteLivedIntangibleAssetExpectedAmortization


Finite
Period End2020-12-31
Value4661000.0
Percentage of FiniteLivedIntangibleAssetExpectedAmortization100.0

zyme:IndefiniteLivedIntangibleAssetsImpairment us-gaap:IndefiniteLivedIntangibleAssetsByMajorClass

zyme:IndefiniteLivedIntangibleAssetsImpairment

zyme:IndefiniteLivedIntangibleAssetsInProcessResearchAndDevelopment


Indefinite
Period End2020-12-312019-12-312019-09-302019-06-302019-03-312018-12-312017-12-312016-12-31
Value3072000.0-3072000.0-3072000.0-3072000.0-2304000.0-2304000.0-2304000.0-768000.0
Percentage of IndefiniteLivedIntangibleAssetsImpairment100.0100.0100.0100.0100.0100.0100.0100.0

zyme:LeaseLiability

zyme:LeaseLiability


Lease
Period End2021-06-302021-03-312020-12-312020-09-302020-06-302020-03-312019-12-312019-09-302019-06-302019-03-312018-12-31
Value318.4218.6617.9828.5799.1076.9376.8117.8888.1140.057
Percentage of LeaseLiability100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0

zyme:LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount

zyme:LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount


Lessee
Period End2021-06-302021-03-312020-12-312020-09-30
Value3.922272624
Percentage of LesseeOperatingLeaseLeaseNotYetCommencedUndiscountedAmount100.0100.0100.0100.0

zyme:LiabilitiesFromInLicensingAgreements

zyme:LiabilitiesFromInLicensingAgreements


Liabilities
Period End2021-06-302021-03-312020-12-31
Value1150000.01450000.01450000.0
Percentage of LiabilitiesFromInLicensingAgreements100.0100.0100.0

zyme:LiabilityForInLicensingAgreement

zyme:LiabilityForInLicensingAgreement


Liability
Period End2020-09-302020-06-302019-12-31
Value1450000.01450000.00
Percentage of LiabilityForInLicensingAgreement100.0100.00.0

zyme:NetMonetaryAssetsDenominatedInForeignCurrency

zyme:NetMonetaryAssetsDenominatedInForeignCurrency


Net
Period End2021-06-302021-03-312020-12-31
Value162219
Percentage of NetMonetaryAssetsDenominatedInForeignCurrency100.0100.0100.0

zyme:ShareBasedCompensationByShareBasedPaymentAwardUnamortizedCompensationExpense

zyme:ShareBasedCompensationByShareBasedPaymentAwardUnamortizedCompensationExpense


Share
Period End2021-03-312020-09-302020-03-312019-03-312018-03-31
Value5230352213
Percentage of ShareBasedCompensationByShareBasedPaymentAwardUnamortizedCompensationExpense100.0100.0100.0100.0100.0

Line plots across dimensions of each concept


TTM Greenblatt ROC
_
(None,)
T T M  Greenblatt  R O C_
us-gaap:AllocatedShareBasedCompensationExpense
us-gaap:AwardType
(None,)
Allocated Share Based Compensation Expenseus-gaap: Award Type
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components
us-gaap:PropertyPlantAndEquipmentGross
us-gaap:PropertyPlantAndEquipmentByType
(None,)
Property Plant And Equipment Grossus-gaap: Property Plant And Equipment By Type
us-gaap:StockholdersEquity
us-gaap:StatementEquityComponents
(None,)
Stockholders Equityus-gaap: Statement Equity Components