Dulaglutide (Trulicity)

GLP-1 agonist · GLP-1 class · sc weekly · Eli Lilly

Top dose
4.5 mg
HbA1c reduction
-1.77%
at week 36 · efficacy
AE discontinuation
6.0%
Status
approved

Pivotal trial

Trial
AWARD-11
Indication
type 2 diabetes
Duration
36 weeks
ClinicalTrials.gov
NCT03495102
Sponsor
Eli Lilly

Notes

AWARD-11 (Frias 2021): dulaglutide 4.5 mg HbA1c -1.77% vs 1.5 mg -1.54%, baseline 8.6%. Established weekly GLP-1; included as the incumbent benchmark for the next-gen race.

Publication

Diabetes Care 2021 (AWARD-11)