Lilly's triple agonist retatrutide delivered powerful weight loss in pivotal Phase 3 obesity trial (TRIUMPH-1)
Eli Lilly · 2026-05-21
TRIUMPH-1 Phase 3: retatrutide 12 mg -28.3% (efficacy estimand) / -25.0% (treatment-regimen) at 80 weeks vs placebo -2.2%. Diagnosis-based T2D exclusion, no HbA1c screen (same as SCALE/liraglutide approach). NCT05929066.
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