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2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Common Stock Value 0.24 0.24 0.22 0.22 0.22 0.16 0.14 0.14 0.14 0.14 0.14 0.14 0.13 0.10 0.08 0.08 0.08 0.08 0.08 0.08 0.08 0.07 0.07 0.07 NA

Common Stock Par Or Stated Value Per Share 0.00 0.00 0.00 0.00 NA 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NA

dei: Entity Common Stock Shares Outstanding NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Weighted Average Number Of Diluted Shares Outstanding 239.80 NA 215.10 NA 214.54 NA NA NA NA NA NA NA NA NA NA NA NA NA 78.67 78.51 NA NA 68.10 67.23 NA

Weighted Average Number Of Shares Outstanding Basic 239.80 NA 215.10 NA 214.54 NA NA NA NA NA NA NA NA NA NA NA NA NA 78.67 78.51 NA NA 68.10 67.23 NA

Weighted Average Number Of Share Outstanding Basic And Diluted NA NA NA NA 214.54 NA 141.19 141.02 140.85 NA 140.63 135.63 130.70 NA 83.16 83.08 82.91 NA 78.67 78.51 75.62 NA NA NA NA

Earnings Per Share Basic -0.04 -0.04 -0.04 -0.06 -0.11 1.29 -0.13 -0.12 -0.15 NA NA NA NA NA NA NA NA NA -0.23 -0.30 NA NA -0.01 -0.16 NA

Earnings Per Share Diluted -0.04 -0.04 -0.04 -0.06 -0.11 1.29 -0.13 -0.12 -0.15 NA NA NA NA NA NA NA NA NA -0.23 -0.30 NA NA -0.01 -0.16 NA

Earnings Per Share Basic And Diluted NA NA NA -0.06 -0.11 NA -0.13 -0.12 -0.15 -0.12 -0.13 -0.13 -0.15 -0.09 -0.20 -0.22 -0.15 -0.37 -0.23 -0.30 -0.32 -0.19 -0.01 -0.16 -0.65

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Revenue From Contract With Customer Excluding Assessed Tax 0.00 0.01 2.91 0.00 0.40 0.00 0.00 0.00 0.15 1.60 1.60 1.60 1.60 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.07

Revenue From Contract With Customer Including Assessed Tax 0.00 0.01 2.91 0.00 0.40 0.00 0.00 0.00 0.15 1.60 1.60 1.60 1.60 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.07

Revenues 0.00 0.01 2.91 0.00 0.40 0.00 0.00 0.00 0.15 1.60 1.60 1.60 1.60 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.07

Operating Expenses 7.99 8.53 11.18 11.05 22.69 12.76 12.57 12.38 16.34 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Research And Development Expense 5.19 5.61 7.89 8.22 14.52 8.20 8.26 7.49 10.18 11.18 11.11 10.83 11.97 2.72 6.25 14.78 19.11 34.98 16.21 18.26 13.98 12.65 10.67 9.12 24.64

General And Administrative Expense 3.04 2.92 3.28 2.10 8.17 4.56 4.31 4.89 6.16 3.85 3.57 3.78 3.60 4.20 3.07 3.72 4.67 4.06 5.71 4.90 4.85 3.97 3.74 3.92 3.35

Operating Income Loss -7.98 -8.52 -8.26 -11.05 -22.30 -12.76 -12.57 -12.38 -16.20 -13.44 -13.08 -13.01 -13.96 -6.72 -9.12 -18.30 -23.58 -38.84 -21.73 -22.97 -18.63 -16.42 -14.21 -12.85 -27.93

Interest Expense 1.07 0.89 0.84 0.74 0.44 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Interest Expense Debt 1.10 0.90 0.80 0.80 0.40 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Interest Paid Net 1.62 0.57 0.60 0.49 NA 0.00 0.00 NA NA 0.00 0.00 NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Net Income Loss -8.77 -9.16 -8.85 -11.79 -22.73 194.54 -12.59 -12.03 -16.02 -18.27 -12.70 -12.86 -15.49 -8.90 -16.71 -18.69 -12.80 -30.23 -17.82 -23.61 -24.47 -13.24 -0.80 -10.72 -39.01

Net Income Loss Available To Common Stockholders Basic NA NA NA NA NA 194.54 -18.66 -17.49 -21.14 -18.27 -17.60 -17.73 -19.66 NA NA NA NA NA NA NA NA NA NA NA NA

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Assets 27.93 64.94 67.34 94.86 113.76 95.05 66.80 76.38 87.46 105.61 116.56 126.81 94.49 71.75 29.48 45.60 63.35 83.40 105.64 122.38 140.87 108.11 122.28 132.82 NA

Liabilities 6.28 26.38 35.23 36.81 45.05 9.49 62.79 61.19 61.57 58.42 57.29 56.85 59.95 22.37 25.85 26.27 25.45 34.96 46.61 46.74 43.17 36.50 38.16 48.69 NA

Liabilities And Stockholders Equity 27.93 64.94 67.34 94.86 113.76 95.05 66.80 76.38 87.46 105.61 116.56 126.81 94.49 71.75 29.48 45.60 63.35 83.40 105.64 122.38 140.87 108.11 122.28 132.82 NA

Stockholders Equity 21.65 38.55 32.11 58.06 68.71 85.56 -156.41 -139.24 -123.15 -96.81 -79.80 -64.27 -94.90 49.38 3.63 19.33 37.89 48.45 59.03 75.64 97.70 71.61 84.11 84.13 NA

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Assets Current 18.78 53.80 55.51 78.83 96.55 84.28 47.16 52.99 72.11 90.78 114.89 125.13 92.75 70.30 27.27 43.03 60.56 80.28 102.58 119.44 138.81 106.11 120.42 131.30 NA

Cash And Cash Equivalents At Carrying Value 18.32 39.06 37.81 76.05 91.72 61.73 31.73 40.40 51.11 70.95 84.41 97.19 66.45 68.20 23.63 38.93 55.66 73.31 95.33 110.39 128.01 104.71 118.93 130.28 124.04

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents 18.32 53.00 51.74 76.05 91.72 61.73 32.12 40.79 51.50 71.33 84.79 97.58 66.83 NA NA NA NA NA NA NA NA NA NA NA NA

Receivables Net Current 0.00 0.00 2.91 1.11 1.51 1.86 1.02 0.66 0.02 0.02 0.01 0.04 0.07 0.14 0.45 0.03 0.07 0.06 0.01 NA NA 0.08 NA NA NA

Prepaid Expense And Other Assets Current 0.46 0.80 0.85 1.67 3.32 20.69 14.41 11.93 20.99 19.82 30.47 27.89 26.24 1.95 3.19 4.07 4.83 6.91 7.24 9.05 10.80 1.31 1.41 1.02 NA

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Property Plant And Equipment Gross NA 18.27 NA 18.35 NA 5.30 NA NA NA 4.84 NA NA NA 2.95 NA NA NA 3.92 NA NA NA 2.47 NA NA NA

Accumulated Depreciation Depletion And Amortization Property Plant And Equipment NA 9.81 NA 7.41 NA 4.20 NA NA NA 3.63 NA NA NA 2.15 NA NA NA 1.92 NA NA NA 1.32 NA NA NA

Property Plant And Equipment Net 7.21 8.46 9.05 10.94 11.66 1.10 1.34 1.33 1.24 1.21 1.05 1.06 1.12 0.80 1.34 1.71 1.91 1.99 2.11 1.98 1.18 1.14 0.89 0.55 NA

Other Assets Noncurrent 0.50 0.50 0.50 0.63 0.00 9.54 18.17 21.93 13.97 13.48 0.50 0.49 0.49 0.53 0.74 0.73 0.74 1.00 0.82 0.82 0.79 0.77 0.88 0.88 NA

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Liabilities Current 5.05 24.17 32.87 16.04 28.17 9.48 60.18 9.31 10.06 20.86 18.19 15.99 17.46 7.79 13.36 21.00 20.36 18.86 21.74 17.78 14.33 13.36 11.77 8.69 NA

Long Term Debt Current NA 16.77 22.67 7.87 12.04 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Accounts Payable Current 1.48 1.39 1.98 1.37 1.46 0.71 1.27 0.59 0.61 4.42 1.52 0.08 0.23 0.42 0.89 1.17 0.98 1.51 4.25 1.47 1.98 1.73 2.16 1.78 NA

Other Accrued Liabilities Current NA 0.17 NA 0.17 NA 0.11 NA NA NA 0.22 NA NA NA 0.23 NA NA NA 0.90 NA NA NA 0.35 NA NA NA

Accrued Liabilities Current 3.23 5.45 7.67 6.08 13.96 8.76 9.38 8.66 8.88 9.91 10.11 9.35 10.69 6.36 11.57 18.97 18.52 16.52 16.68 15.50 11.53 10.82 8.79 6.08 NA

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Long Term Debt Noncurrent NA NA NA 16.25 12.17 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Other Liabilities Noncurrent NA 0.03 0.03 NA NA NA NA NA NA NA NA NA NA 0.02 NA 2.58 2.17 12.96 21.53 25.47 25.19 19.43 22.58 36.01 NA

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Stockholders Equity 21.65 38.55 32.11 58.06 68.71 85.56 -156.41 -139.24 -123.15 -96.81 -79.80 -64.27 -94.90 49.38 3.63 19.33 37.89 48.45 59.03 75.64 97.70 71.61 84.11 84.13 NA

Common Stock Value 0.24 0.24 0.22 0.22 0.22 0.16 0.14 0.14 0.14 0.14 0.14 0.14 0.13 0.10 0.08 0.08 0.08 0.08 0.08 0.08 0.08 0.07 0.07 0.07 NA

Additional Paid In Capital Common Stock 920.86 918.94 903.37 900.69 899.55 651.73 604.65 609.25 613.30 615.49 619.23 622.05 578.57 386.51 331.82 330.74 327.50 325.18 305.54 304.22 302.60 246.52 244.67 243.81 NA

Retained Earnings Accumulated Deficit -899.45 -880.63 -871.47 -842.85 -831.06 -566.33 -761.21 -748.62 -736.59 -712.44 -699.17 -686.47 -673.61 -340.83 NA NA NA NA NA NA NA NA NA NA NA

Stock Issued During Period Value New Issues 0.00 NA NA NA NA NA NA NA NA 0.00 0.00 NA NA NA NA NA NA NA 0.00 0.00 49.17 NA NA NA NA

Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value 0.91 0.88 0.81 0.92 2.37 0.68 1.48 1.71 3.66 2.29 2.08 2.06 2.02 1.02 0.81 0.13 1.54 1.40 1.19 1.08 1.21 0.86 0.59 NA NA

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Net Cash Provided By Used In Operating Activities -7.00 -7.13 -6.14 -15.13 -9.58 -11.82 -8.51 -10.17 -18.96 -12.16 -12.71 NA NA -9.04 -15.50 -16.72 -18.24 -21.50 -14.71 -16.77 -25.86 -13.75 -11.10 -5.82 -8.17

Net Cash Provided By Used In Investing Activities -0.14 -0.09 -0.01 -0.36 -0.37 0.09 -0.17 -0.23 -0.15 -0.28 -0.08 NA NA -0.01 -0.00 -0.00 -0.11 -0.08 -0.38 -0.95 -0.15 -0.35 -0.41 -0.17 -0.23

Net Cash Provided By Used In Financing Activities -11.98 8.47 NA -0.19 24.93 41.35 0.00 -0.30 -0.73 -1.03 0.00 NA NA 53.63 0.20 -0.00 0.71 -0.45 0.02 0.10 49.31 -0.12 0.16 12.23 72.04

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Net Cash Provided By Used In Operating Activities -7.00 -7.13 -6.14 -15.13 -9.58 -11.82 -8.51 -10.17 -18.96 -12.16 -12.71 NA NA -9.04 -15.50 -16.72 -18.24 -21.50 -14.71 -16.77 -25.86 -13.75 -11.10 -5.82 -8.17

Net Income Loss -8.77 -9.16 -8.85 -11.79 -22.73 194.54 -12.59 -12.03 -16.02 -18.27 -12.70 -12.86 -15.49 -8.90 -16.71 -18.69 -12.80 -30.23 -17.82 -23.61 -24.47 -13.24 -0.80 -10.72 -39.01

Increase Decrease In Accounts Payable 0.20 -0.64 1.51 -0.23 0.48 -0.56 0.68 -0.02 -3.81 2.89 1.44 -0.14 0.07 -0.47 -0.27 0.18 -0.53 -2.74 2.78 -0.52 0.26 -0.43 0.38 -0.07 0.82

Share Based Compensation 0.91 0.88 0.81 0.92 2.37 0.68 1.48 1.71 3.66 2.29 2.08 2.06 2.02 1.02 0.81 0.13 1.54 1.40 1.19 1.08 1.21 0.86 0.59 0.61 0.70

Amortization Of Financing Costs 0.87 0.35 0.23 0.23 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

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Net Cash Provided By Used In Investing Activities -0.14 -0.09 -0.01 -0.36 -0.37 0.09 -0.17 -0.23 -0.15 -0.28 -0.08 NA NA -0.01 -0.00 -0.00 -0.11 -0.08 -0.38 -0.95 -0.15 -0.35 -0.41 -0.17 -0.23

Payments To Acquire Property Plant And Equipment 0.14 0.12 0.01 0.36 0.37 -0.09 0.17 0.23 0.15 0.28 0.08 0.03 0.36 0.01 0.00 0.00 0.11 0.08 0.38 0.95 0.15 0.35 0.41 0.17 0.23

2023-06-30 2022-12-31 2022-09-30 2021-12-31 2021-09-30 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31

Net Cash Provided By Used In Financing Activities -11.98 8.47 NA -0.19 24.93 41.35 0.00 -0.30 -0.73 -1.03 0.00 NA NA 53.63 0.20 -0.00 0.71 -0.45 0.02 0.10 49.31 -0.12 0.16 12.23 72.04

Payments For Repurchase Of Common Stock NA 0.00 NA NA NA 0.35 0.00 NA NA NA NA NA NA 0.25 0.00 0.00 0.25 0.45 0.10 0.00 0.00 0.20 0.00 0.00 0.08

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Revenues 0.00 0.01 2.91 0.00 0.40 0.00 0.00 0.00 0.15 1.60 1.60 1.60 1.60 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.07

Revenue From Contract With Customer Excluding Assessed Tax 0.00 0.01 2.91 0.00 0.40 0.00 0.00 0.00 0.15 1.60 1.60 1.60 1.60 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.07

Collaboration Agreement With Solasia Pharma Kk 0.00 NA NA NA 0.40 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Revenue From Contract With Customer Including Assessed Tax 0.00 0.01 2.91 0.00 0.40 0.00 0.00 0.00 0.15 1.60 1.60 1.60 1.60 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.07

Plots across concepts

IncomeStatement

Net Income Loss

Balance Sheet

Operating Lease Right Of Use Asset

Assets

Operating Lease Right Of Use Asset

Current Assets

Prepaid Expense And Other Assets Current

NonCurrent Assets

Other Assets Noncurrent

PropertyPlantAndEquipmentNet

Property Plant And Equipment Net

Liabilities

Operating Lease Liability

Current Liabilities

Other Accrued Liabilities Current

Noncurrent Liabilities

Other Liabilities Noncurrent

Stockholders Equity

Retained Earnings Accumulated Deficit

CashFlow

Net Cash Provided By Used In Financing Activities

NetCashProvidedByUsedInOperatingActivities

Net Income Loss

NetCashProvidedByUsedInInvestingActivities

Net Cash Provided By Used In Investing Activities

NetCashProvidedByUsedInFinancingActivities

Net Cash Provided By Used In Financing Activities

Shares

Weighted Average Number Of Share Outstanding Basic And Diluted

NonoperatingIncomeExpense

Nonoperating Income Expense

LesseeOperatingLeaseLiabilityPaymentsDue

Lessee Operating Lease Liability Undiscounted Excess Amount

Line plots across dimensions of each concept

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