Twenty of the largest pharmaceutical companies, ranked by how much of their first-half 2026 revenue came from a single molecule. The range runs from 76.8% to 5.6%, one drug appears twice at wildly different weights, and two companies changed their largest product within the year.
The largest sectors and companies of the S&P 500 by market capitalization have changed over time. Prior to the dot-com bubble bursting in March 2000 the technology sector made up a third of the S&P 500 thanks to companies such as Microsoft, Cisco, Intel, Lucent Technologies, IBM, America Onl